Result of FASTA (omim) for
pF1KB6702
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6702, 128 aa
1>>>pF1KB6702 128 - 128 aa - 128 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6065+/-0.000311; mu= 14.4144+/- 0.019
mean_var=60.4300+/-11.610, 0's: 0 Z-trim(116.1): 31 B-trim: 43 in 1/54
Lambda= 0.164986
statistics sampled from 26972 (27004) to 26972 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.317), width: 16
Scan time: 5.080
The best scores are: opt bits E(85289)
NP_002695 (OMIM: 121010) platelet basic protein pr ( 128) 821 203.2 9.7e-53
NP_001502 (OMIM: 155730) growth-regulated alpha pr ( 107) 299 78.8 2.1e-15
NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 p ( 114) 284 75.3 2.7e-14
NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 p ( 107) 275 73.1 1.1e-13
NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 p ( 107) 264 70.5 6.9e-13
NP_002610 (OMIM: 173460) platelet factor 4 precurs ( 101) 255 68.4 2.9e-12
XP_005265753 (OMIM: 173460) PREDICTED: platelet fa ( 110) 253 67.9 4.3e-12
NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 p ( 114) 251 67.4 6.2e-12
NP_002611 (OMIM: 173461) platelet factor 4 variant ( 104) 237 64.1 5.8e-11
NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 221 60.3 7.9e-10
NP_002407 (OMIM: 601704) C-X-C motif chemokine 9 p ( 125) 179 50.3 9.6e-07
NP_001556 (OMIM: 147310) C-X-C motif chemokine 10 ( 98) 158 45.3 2.5e-05
XP_006714126 (OMIM: 605149) PREDICTED: C-X-C motif ( 109) 140 41.0 0.00054
NP_006410 (OMIM: 605149) C-X-C motif chemokine 13 ( 109) 140 41.0 0.00054
NP_005400 (OMIM: 604852) C-X-C motif chemokine 11 ( 94) 126 37.6 0.0048
NP_001289052 (OMIM: 604852) C-X-C motif chemokine ( 106) 123 37.0 0.0087
>>NP_002695 (OMIM: 121010) platelet basic protein prepro (128 aa)
initn: 821 init1: 821 opt: 821 Z-score: 1067.8 bits: 203.2 E(85289): 9.7e-53
Smith-Waterman score: 821; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128)
10 20 30 40 50 60
pF1KB6 MSLRLDTTPSCNSARPLHALQVLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSLRLDTTPSCNSARPLHALQVLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKK
70 80 90 100 110 120
pF1KB6 LAGDESAD
::::::::
NP_002 LAGDESAD
>>NP_001502 (OMIM: 155730) growth-regulated alpha protei (107 aa)
initn: 350 init1: 296 opt: 299 Z-score: 397.4 bits: 78.8 E(85289): 2.1e-15
Smith-Waterman score: 299; 52.4% identity (81.7% similar) in 82 aa overlap (45-126:26-106)
20 30 40 50 60 70
pF1KB6 RPLHALQVLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAELRCMCIKTTSGIHP
.: :.. . ... .::::.:..: .::::
NP_001 MARAALSAAPSNPRLLRVALLLLLLVAAGRRAA-GASVATELRCQCLQTLQGIHP
10 20 30 40 50
80 90 100 110 120
pF1KB6 KNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
:::::..: . : :: :.:::::::.::: ::.: .: .:::..: : .:.:
NP_001 KNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN
60 70 80 90 100
>>NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 precu (114 aa)
initn: 327 init1: 284 opt: 284 Z-score: 377.7 bits: 75.3 E(85289): 2.7e-14
Smith-Waterman score: 284; 56.2% identity (90.6% similar) in 64 aa overlap (60-123:46-109)
30 40 50 60 70 80
pF1KB6 LTALASSTKGQTKRNLAKGKEESLDSDLYAELRCMCIKTTSGIHPKNIQSLEVIGKGTHC
::::.:..::.:.::: :..:.:.. : .:
NP_002 SSLCALLVLLLLLTQPGPIASAGPAAAVLRELRCVCLQTTQGVHPKMISNLQVFAIGPQC
20 30 40 50 60 70
90 100 110 120
pF1KB6 NQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
..:::.:.::.:..:::::.:: .::..:: : :
NP_002 SKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN
80 90 100 110
>>NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 precu (107 aa)
initn: 306 init1: 270 opt: 275 Z-score: 366.5 bits: 73.1 E(85289): 1.1e-13
Smith-Waterman score: 275; 48.8% identity (79.3% similar) in 82 aa overlap (45-126:25-106)
20 30 40 50 60 70
pF1KB6 RPLHALQVLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAELRCMCIKTTSGIHP
:. ..... . : .::::.:..: .:::
NP_002 MARATLSAAPSNPRLLRVALLLLLLVAASRRAAGAPLATELRCQCLQTLQGIHL
10 20 30 40 50
80 90 100 110 120
pF1KB6 KNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
:::::..: . : :: :.:::::::.:.: ::.: .: .:::..: : . .:
NP_002 KNIQSVKVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN
60 70 80 90 100
>>NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 precu (107 aa)
initn: 315 init1: 261 opt: 264 Z-score: 352.3 bits: 70.5 E(85289): 6.9e-13
Smith-Waterman score: 264; 48.1% identity (81.8% similar) in 77 aa overlap (45-121:25-101)
20 30 40 50 60 70
pF1KB6 RPLHALQVLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAELRCMCIKTTSGIHP
:. ..... ... .::::.:..: .:::
NP_002 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHL
10 20 30 40 50
80 90 100 110 120
pF1KB6 KNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
:::::..: . : :: :.:::::::.:.: ::.: .: ..::..: :
NP_002 KNIQSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
60 70 80 90 100
>>NP_002610 (OMIM: 173460) platelet factor 4 precursor [ (101 aa)
initn: 245 init1: 212 opt: 255 Z-score: 341.1 bits: 68.4 E(85289): 2.9e-12
Smith-Waterman score: 255; 52.9% identity (80.0% similar) in 70 aa overlap (52-121:30-99)
30 40 50 60 70 80
pF1KB6 VLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAELRCMCIKTTSGIHPKNIQSLE
: ... ..:.:.:.:::: ..:..: :::
NP_002 MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLE
10 20 30 40 50
90 100 110 120
pF1KB6 VIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
:: : :: ...:::::.::::::: .:: :::..: :
NP_002 VIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
60 70 80 90 100
>>XP_005265753 (OMIM: 173460) PREDICTED: platelet factor (110 aa)
initn: 225 init1: 212 opt: 253 Z-score: 338.0 bits: 67.9 E(85289): 4.3e-12
Smith-Waterman score: 253; 58.1% identity (82.3% similar) in 62 aa overlap (60-121:47-108)
30 40 50 60 70 80
pF1KB6 LTALASSTKGQTKRNLAKGKEESLDSDLYAELRCMCIKTTSGIHPKNIQSLEVIGKGTHC
.:.:.:.:::: ..:..: ::::: : ::
XP_005 VPGAAPAPPTWLEQLLSGGGVIYAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHC
20 30 40 50 60 70
90 100 110 120
pF1KB6 NQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
...:::::.::::::: .:: :::..: :
XP_005 PTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
80 90 100 110
>>NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 precu (114 aa)
initn: 297 init1: 248 opt: 251 Z-score: 335.2 bits: 67.4 E(85289): 6.2e-12
Smith-Waterman score: 256; 40.5% identity (65.3% similar) in 121 aa overlap (7-121:2-107)
10 20 30 40 50
pF1KB6 MSLRLDTTPSCNSAR---PLHALQVLLLLSLLLTA---LASSTKGQTKRNLAKGKEESLD
. :: .:: : .: .:: : :::: :::. : .
NP_002 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASA--GPV-------------
10 20 30 40
60 70 80 90 100 110
pF1KB6 SDLYAELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIK
: . .:::: :...: ..::.: .:.:. : .:..:::.:.::.:...::::.:: .:
NP_002 SAVLTELRCTCLRVTLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLK
50 60 70 80 90 100
120
pF1KB6 KIVQKKLAGDESAD
:..:: :
NP_002 KVIQKILDSGNKKN
110
>>NP_002611 (OMIM: 173461) platelet factor 4 variant pre (104 aa)
initn: 209 init1: 196 opt: 237 Z-score: 317.8 bits: 64.1 E(85289): 5.8e-11
Smith-Waterman score: 241; 43.6% identity (70.3% similar) in 101 aa overlap (21-121:15-102)
10 20 30 40 50 60
pF1KB6 MSLRLDTTPSCNSARPLHALQVLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAE
: .:.:.::: .. . .:... : :.::
NP_002 MSSAARSRLTRATRQEMLFLALLLLPVVVA--------FARAEAEE-DGDL---
10 20 30 40
70 80 90 100 110 120
pF1KB6 LRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKK
.:.:.:::: ..:..: ::::: : :: ...:::::.::::::: .: :::....
NP_002 -QCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEH
50 60 70 80 90 100
pF1KB6 LAGDESAD
:
NP_002 LES
>>NP_000575 (OMIM: 146930) interleukin-8 precursor [Homo (99 aa)
initn: 199 init1: 150 opt: 221 Z-score: 297.5 bits: 60.3 E(85289): 7.9e-10
Smith-Waterman score: 221; 47.8% identity (75.4% similar) in 69 aa overlap (60-127:31-99)
30 40 50 60 70 80
pF1KB6 LTALASSTKGQTKRNLAKGKEESLDSDLYAELRCMCIKTTSG-IHPKNIQSLEVIGKGTH
::::.:::: : .::: :. :.:: .: :
NP_000 MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPH
10 20 30 40 50 60
90 100 110 120
pF1KB6 CNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
: ..:.:. :.:::..:::: ....:.: : :..
NP_000 CANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
70 80 90
128 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:26:13 2016 done: Fri Nov 4 23:26:14 2016
Total Scan time: 5.080 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]