Result of FASTA (omim) for
pF1KB6666
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6666, 453 aa
1>>>pF1KB6666 453 - 453 aa - 453 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9693+/-0.000441; mu= 8.7289+/- 0.027
mean_var=95.3657+/-18.671, 0's: 0 Z-trim(111.8): 80 B-trim: 605 in 1/53
Lambda= 0.131334
statistics sampled from 20449 (20531) to 20449 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.241), width: 16
Scan time: 7.270
The best scores are: opt bits E(85289)
NP_068656 (OMIM: 134850,202400,616004) fibrinogen ( 453) 3132 604.2 2.2e-172
NP_000500 (OMIM: 134850,202400,616004) fibrinogen ( 437) 2991 577.5 2.4e-164
XP_016868722 (OMIM: 605776) PREDICTED: fibrinogen- ( 282) 756 154.0 4.8e-37
NP_671736 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 756 154.0 5.3e-37
NP_963847 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 756 154.0 5.3e-37
NP_004458 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 756 154.0 5.3e-37
NP_963846 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 756 154.0 5.3e-37
XP_016868721 (OMIM: 605776) PREDICTED: fibrinogen- ( 312) 756 154.0 5.3e-37
NP_000499 (OMIM: 105200,134820,202400,616004) fibr ( 866) 705 144.5 1.1e-33
NP_005132 (OMIM: 134830,202400,616004) fibrinogen ( 491) 560 116.9 1.2e-25
NP_001171670 (OMIM: 134830,202400,616004) fibrinog ( 432) 526 110.5 9.3e-24
NP_006673 (OMIM: 605351) fibroleukin precursor [Ho ( 439) 485 102.7 2.1e-21
NP_004664 (OMIM: 603874) angiopoietin-related prot ( 491) 456 97.2 1e-19
XP_005245634 (OMIM: 603874) PREDICTED: angiopoieti ( 491) 456 97.2 1e-19
NP_001186788 (OMIM: 601667) angiopoietin-1 isoform ( 497) 454 96.8 1.4e-19
XP_005272541 (OMIM: 605910,615881) PREDICTED: angi ( 424) 450 96.1 2e-19
XP_011527541 (OMIM: 603705) PREDICTED: angiopoieti ( 451) 449 95.9 2.4e-19
NP_057069 (OMIM: 603705) angiopoietin-4 isoform 1 ( 503) 449 95.9 2.6e-19
NP_001137 (OMIM: 601667) angiopoietin-1 isoform 1 ( 498) 442 94.6 6.6e-19
NP_001994 (OMIM: 601252) ficolin-1 precursor [Homo ( 326) 438 93.8 7.5e-19
NP_036230 (OMIM: 605001) angiopoietin-related prot ( 493) 432 92.7 2.4e-18
NP_001309738 (OMIM: 603705) angiopoietin-4 isoform ( 410) 425 91.3 5.1e-18
NP_835228 (OMIM: 607666) angiopoietin-related prot ( 388) 423 90.9 6.3e-18
NP_001300980 (OMIM: 601667) angiopoietin-1 isoform ( 298) 420 90.3 7.4e-18
NP_116232 (OMIM: 613357) fibrinogen C domain-conta ( 461) 419 90.2 1.3e-17
NP_001138578 (OMIM: 613357) fibrinogen C domain-co ( 461) 419 90.2 1.3e-17
XP_006717078 (OMIM: 601624) PREDICTED: ficolin-2 i ( 264) 412 88.8 1.9e-17
NP_056652 (OMIM: 601624) ficolin-2 isoform b precu ( 275) 412 88.8 2e-17
XP_011516694 (OMIM: 601624) PREDICTED: ficolin-2 i ( 302) 412 88.8 2.1e-17
NP_004099 (OMIM: 601624) ficolin-2 isoform a precu ( 313) 412 88.8 2.2e-17
NP_775628 (OMIM: 604973,613860) ficolin-3 isoform ( 288) 407 87.9 3.9e-17
NP_003656 (OMIM: 604973,613860) ficolin-3 isoform ( 299) 407 87.9 4.1e-17
XP_016868807 (OMIM: 601922) PREDICTED: angiopoieti ( 443) 404 87.3 8.7e-17
NP_001112359 (OMIM: 601922) angiopoietin-2 isoform ( 495) 404 87.4 9.6e-17
NP_001112360 (OMIM: 601922) angiopoietin-2 isoform ( 444) 403 87.2 9.9e-17
NP_001138 (OMIM: 601922) angiopoietin-2 isoform a ( 496) 403 87.2 1.1e-16
NP_002395 (OMIM: 600596) microfibril-associated gl ( 255) 378 82.4 1.6e-15
NP_001185624 (OMIM: 600596) microfibril-associated ( 279) 378 82.4 1.7e-15
NP_055310 (OMIM: 604774,605019) angiopoietin-relat ( 460) 355 78.1 5.6e-14
NP_647475 (OMIM: 605910,615881) angiopoietin-relat ( 406) 352 77.5 7.4e-14
XP_011541037 (OMIM: 607666) PREDICTED: angiopoieti ( 323) 342 75.6 2.2e-13
XP_005272542 (OMIM: 605910,615881) PREDICTED: angi ( 386) 336 74.4 5.8e-13
NP_001315564 (OMIM: 601995) tenascin-R isoform 2 [ (1025) 310 69.6 4.3e-11
NP_115859 (OMIM: 600985,606408,615963) tenascin-X ( 673) 306 68.8 4.9e-11
XP_011508251 (OMIM: 601995) PREDICTED: tenascin-R (1199) 310 69.7 5e-11
NP_003276 (OMIM: 601995) tenascin-R isoform 1 prec (1358) 310 69.7 5.6e-11
XP_016857708 (OMIM: 601995) PREDICTED: tenascin-R (1358) 310 69.7 5.6e-11
XP_016857707 (OMIM: 601995) PREDICTED: tenascin-R (1358) 310 69.7 5.6e-11
XP_005252032 (OMIM: 187380,615629) PREDICTED: tena (1564) 300 67.8 2.4e-10
XP_005252031 (OMIM: 187380,615629) PREDICTED: tena (1655) 300 67.8 2.5e-10
>>NP_068656 (OMIM: 134850,202400,616004) fibrinogen gamm (453 aa)
initn: 3132 init1: 3132 opt: 3132 Z-score: 3215.7 bits: 604.2 E(85289): 2.2e-172
Smith-Waterman score: 3132; 100.0% identity (100.0% similar) in 453 aa overlap (1-453:1-453)
10 20 30 40 50 60
pF1KB6 MSWSLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MSWSLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 DIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 DIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 FGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 FGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 RLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 WMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 WMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
370 380 390 400 410 420
430 440 450
pF1KB6 GEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
:::::::::::::::::::::::::::::::::
NP_068 GEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
430 440 450
>>NP_000500 (OMIM: 134850,202400,616004) fibrinogen gamm (437 aa)
initn: 2991 init1: 2991 opt: 2991 Z-score: 3071.6 bits: 577.5 E(85289): 2.4e-164
Smith-Waterman score: 2991; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KB6 MSWSLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSWSLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 DIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 FGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 RLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 WMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
370 380 390 400 410 420
430 440 450
pF1KB6 GEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
:::::::::::::
NP_000 GEGQQHHLGGAKQAGDV
430
>>XP_016868722 (OMIM: 605776) PREDICTED: fibrinogen-like (282 aa)
initn: 549 init1: 262 opt: 756 Z-score: 786.1 bits: 154.0 E(85289): 4.8e-37
Smith-Waterman score: 756; 42.3% identity (71.9% similar) in 274 aa overlap (145-414:16-274)
120 130 140 150 160 170
pF1KB6 MLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDI
:. :..:. . . :.: . : . :.
XP_016 MRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDK-GDENTVIDL
10 20 30 40
180 190 200 210 220 230
pF1KB6 TGK----DCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDF
.: ::..: : : : ::.: ::::.. .: :::... .:.::::.:.: ::: .:
XP_016 GSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENF
50 60 70 80 90 100
240 250 260 270 280 290
pF1KB6 KKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAM
...: .:..:::.. :.::::...:...:: :.:...: :.. . :.:
XP_016 NRGWKDYENGFGNFVQKHG-EYWLGNKNLHFLTTQE--DYTLKIDLADFEKNSRYAQYKN
110 120 130 140 150 160
300 310 320 330 340 350
pF1KB6 FKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEG
:::: : . :.:. . ..: :::.. : .: : ....::. :.::::: :.:..::
XP_016 FKVGDEKNFYELNIGEYSG-TAGDSLAG-NF--HPEVQWWASHQRMKFSTWDRDHDNYEG
170 180 190 200 210
360 370 380 390 400 410
pF1KB6 NCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTM
::::.: ::::.:.::...::::::.: .:. ::::.: ::. :::.:...:
XP_016 NCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKT------DNGIVWYTWHGWWYSLKSVVM
220 230 240 250 260 270
420 430 440 450
pF1KB6 KIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
:: :
XP_016 KIRPNDFIPNVI
280
>>NP_671736 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa)
initn: 549 init1: 262 opt: 756 Z-score: 785.3 bits: 154.0 E(85289): 5.3e-37
Smith-Waterman score: 756; 42.3% identity (71.9% similar) in 274 aa overlap (145-414:46-304)
120 130 140 150 160 170
pF1KB6 MLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDI
:. :..:. . . :.: . : . :.
NP_671 MGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDK-GDENTVIDL
20 30 40 50 60 70
180 190 200 210 220 230
pF1KB6 TGK----DCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDF
.: ::..: : : : ::.: ::::.. .: :::... .:.::::.:.: ::: .:
NP_671 GSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENF
80 90 100 110 120 130
240 250 260 270 280 290
pF1KB6 KKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAM
...: .:..:::.. :.::::...:...:: :.:...: :.. . :.:
NP_671 NRGWKDYENGFGNFVQKHG-EYWLGNKNLHFLTTQE--DYTLKIDLADFEKNSRYAQYKN
140 150 160 170 180 190
300 310 320 330 340 350
pF1KB6 FKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEG
:::: : . :.:. . ..: :::.. : .: : ....::. :.::::: :.:..::
NP_671 FKVGDEKNFYELNIGEYSG-TAGDSLAG-NF--HPEVQWWASHQRMKFSTWDRDHDNYEG
200 210 220 230 240
360 370 380 390 400 410
pF1KB6 NCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTM
::::.: ::::.:.::...::::::.: .:. ::::.: ::. :::.:...:
NP_671 NCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKT------DNGIVWYTWHGWWYSLKSVVM
250 260 270 280 290 300
420 430 440 450
pF1KB6 KIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
:: :
NP_671 KIRPNDFIPNVI
310
>>NP_963847 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa)
initn: 549 init1: 262 opt: 756 Z-score: 785.3 bits: 154.0 E(85289): 5.3e-37
Smith-Waterman score: 756; 42.3% identity (71.9% similar) in 274 aa overlap (145-414:46-304)
120 130 140 150 160 170
pF1KB6 MLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDI
:. :..:. . . :.: . : . :.
NP_963 MGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDK-GDENTVIDL
20 30 40 50 60 70
180 190 200 210 220 230
pF1KB6 TGK----DCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDF
.: ::..: : : : ::.: ::::.. .: :::... .:.::::.:.: ::: .:
NP_963 GSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENF
80 90 100 110 120 130
240 250 260 270 280 290
pF1KB6 KKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAM
...: .:..:::.. :.::::...:...:: :.:...: :.. . :.:
NP_963 NRGWKDYENGFGNFVQKHG-EYWLGNKNLHFLTTQE--DYTLKIDLADFEKNSRYAQYKN
140 150 160 170 180 190
300 310 320 330 340 350
pF1KB6 FKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEG
:::: : . :.:. . ..: :::.. : .: : ....::. :.::::: :.:..::
NP_963 FKVGDEKNFYELNIGEYSG-TAGDSLAG-NF--HPEVQWWASHQRMKFSTWDRDHDNYEG
200 210 220 230 240
360 370 380 390 400 410
pF1KB6 NCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTM
::::.: ::::.:.::...::::::.: .:. ::::.: ::. :::.:...:
NP_963 NCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKT------DNGIVWYTWHGWWYSLKSVVM
250 260 270 280 290 300
420 430 440 450
pF1KB6 KIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
:: :
NP_963 KIRPNDFIPNVI
310
>>NP_004458 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa)
initn: 549 init1: 262 opt: 756 Z-score: 785.3 bits: 154.0 E(85289): 5.3e-37
Smith-Waterman score: 756; 42.3% identity (71.9% similar) in 274 aa overlap (145-414:46-304)
120 130 140 150 160 170
pF1KB6 MLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDI
:. :..:. . . :.: . : . :.
NP_004 MGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDK-GDENTVIDL
20 30 40 50 60 70
180 190 200 210 220 230
pF1KB6 TGK----DCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDF
.: ::..: : : : ::.: ::::.. .: :::... .:.::::.:.: ::: .:
NP_004 GSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENF
80 90 100 110 120 130
240 250 260 270 280 290
pF1KB6 KKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAM
...: .:..:::.. :.::::...:...:: :.:...: :.. . :.:
NP_004 NRGWKDYENGFGNFVQKHG-EYWLGNKNLHFLTTQE--DYTLKIDLADFEKNSRYAQYKN
140 150 160 170 180 190
300 310 320 330 340 350
pF1KB6 FKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEG
:::: : . :.:. . ..: :::.. : .: : ....::. :.::::: :.:..::
NP_004 FKVGDEKNFYELNIGEYSG-TAGDSLAG-NF--HPEVQWWASHQRMKFSTWDRDHDNYEG
200 210 220 230 240
360 370 380 390 400 410
pF1KB6 NCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTM
::::.: ::::.:.::...::::::.: .:. ::::.: ::. :::.:...:
NP_004 NCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKT------DNGIVWYTWHGWWYSLKSVVM
250 260 270 280 290 300
420 430 440 450
pF1KB6 KIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
:: :
NP_004 KIRPNDFIPNVI
310
>>NP_963846 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa)
initn: 549 init1: 262 opt: 756 Z-score: 785.3 bits: 154.0 E(85289): 5.3e-37
Smith-Waterman score: 756; 42.3% identity (71.9% similar) in 274 aa overlap (145-414:46-304)
120 130 140 150 160 170
pF1KB6 MLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDI
:. :..:. . . :.: . : . :.
NP_963 MGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDK-GDENTVIDL
20 30 40 50 60 70
180 190 200 210 220 230
pF1KB6 TGK----DCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDF
.: ::..: : : : ::.: ::::.. .: :::... .:.::::.:.: ::: .:
NP_963 GSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENF
80 90 100 110 120 130
240 250 260 270 280 290
pF1KB6 KKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAM
...: .:..:::.. :.::::...:...:: :.:...: :.. . :.:
NP_963 NRGWKDYENGFGNFVQKHG-EYWLGNKNLHFLTTQE--DYTLKIDLADFEKNSRYAQYKN
140 150 160 170 180 190
300 310 320 330 340 350
pF1KB6 FKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEG
:::: : . :.:. . ..: :::.. : .: : ....::. :.::::: :.:..::
NP_963 FKVGDEKNFYELNIGEYSG-TAGDSLAG-NF--HPEVQWWASHQRMKFSTWDRDHDNYEG
200 210 220 230 240
360 370 380 390 400 410
pF1KB6 NCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTM
::::.: ::::.:.::...::::::.: .:. ::::.: ::. :::.:...:
NP_963 NCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKT------DNGIVWYTWHGWWYSLKSVVM
250 260 270 280 290 300
420 430 440 450
pF1KB6 KIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
:: :
NP_963 KIRPNDFIPNVI
310
>>XP_016868721 (OMIM: 605776) PREDICTED: fibrinogen-like (312 aa)
initn: 549 init1: 262 opt: 756 Z-score: 785.3 bits: 154.0 E(85289): 5.3e-37
Smith-Waterman score: 756; 42.3% identity (71.9% similar) in 274 aa overlap (145-414:46-304)
120 130 140 150 160 170
pF1KB6 MLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDI
:. :..:. . . :.: . : . :.
XP_016 MGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDK-GDENTVIDL
20 30 40 50 60 70
180 190 200 210 220 230
pF1KB6 TGK----DCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDF
.: ::..: : : : ::.: ::::.. .: :::... .:.::::.:.: ::: .:
XP_016 GSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENF
80 90 100 110 120 130
240 250 260 270 280 290
pF1KB6 KKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAM
...: .:..:::.. :.::::...:...:: :.:...: :.. . :.:
XP_016 NRGWKDYENGFGNFVQKHG-EYWLGNKNLHFLTTQE--DYTLKIDLADFEKNSRYAQYKN
140 150 160 170 180 190
300 310 320 330 340 350
pF1KB6 FKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEG
:::: : . :.:. . ..: :::.. : .: : ....::. :.::::: :.:..::
XP_016 FKVGDEKNFYELNIGEYSG-TAGDSLAG-NF--HPEVQWWASHQRMKFSTWDRDHDNYEG
200 210 220 230 240
360 370 380 390 400 410
pF1KB6 NCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTM
::::.: ::::.:.::...::::::.: .:. ::::.: ::. :::.:...:
XP_016 NCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKT------DNGIVWYTWHGWWYSLKSVVM
250 260 270 280 290 300
420 430 440 450
pF1KB6 KIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
:: :
XP_016 KIRPNDFIPNVI
310
>>NP_000499 (OMIM: 105200,134820,202400,616004) fibrinog (866 aa)
initn: 697 init1: 266 opt: 705 Z-score: 725.8 bits: 144.5 E(85289): 1.1e-33
Smith-Waterman score: 705; 42.6% identity (71.9% similar) in 242 aa overlap (177-415:630-863)
150 160 170 180 190 200
pF1KB6 IVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDI--ANKGAKQSGLYFIKPLKANQQF
.::.:. .. .. :::.. :: ... :
NP_000 SYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIF
600 610 620 630 640 650
210 220 230 240 250 260
pF1KB6 LVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLIST
:::. . : .:: ..:.:.:::..:...: .::.::: :. : ::::::. .::..
NP_000 SVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQ
660 670 680 690 700 710
270 280 290 300 310 320
pF1KB6 QSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDD
.... :::::::: : . :.: :.:: ::. : : . . : ::::. :.
NP_000 RGSV---LRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEG-TAGDALIE---GSV
720 730 740 750 760 770
330 340 350 360 370 380
pF1KB6 PSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYS-KA
.::::.:::::.: : :..: :::: :.:::.:.:.:..:::.:: ::.:. .
NP_000 EEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRN
780 790 800 810 820 830
390 400 410 420 430 440
pF1KB6 STPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETE
..: .::..:.... ::.. . ::: :.
NP_000 NSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ
840 850 860
450
pF1KB6 YDSLYPEDDL
>>NP_005132 (OMIM: 134830,202400,616004) fibrinogen beta (491 aa)
initn: 779 init1: 295 opt: 560 Z-score: 581.4 bits: 116.9 E(85289): 1.2e-25
Smith-Waterman score: 827; 33.2% identity (64.2% similar) in 400 aa overlap (34-415:95-487)
10 20 30 40 50 60
pF1KB6 SLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQTKVD
: : .: ::: : . . : . .
NP_005 PISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQERPIR
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB6 KDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIMKYE
.... :.. .. : . .: : . .. .. ... . .... : .. .. . .
NP_005 NSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQLYID
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB6 ASILTH-DSSIRYLQEIYNSNNQKIVNLKEKV-AQLEAQCQEPCKDTVQIHDITGKDCQD
.. .. ...: :. : .. .:: .:. : ::.: :. :: . .: ..::.:..
NP_005 ETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQME-YCRTPCTVSCNIPVVSGKECEE
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB6 IANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGF
: ::.. : .:.:.: .. . . :::... ..::::.:.: :::::: ..: ::.::
NP_005 IIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGF
250 260 270 280 290 300
250 260 270 280 290
pF1KB6 GHLSPT--GTT------EFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKV
:... . : . :.::::.:: .. .. : : .:.:::.: : :. : :
NP_005 GNVATNTDGKNYCGLPGEYWLGNDKISQLTRMG--PTELLIEMEDWKGDKVKAHYGGFTV
310 320 330 340 350 360
300 310 320 330 340
pF1KB6 GPEADKYRLTYAYFAGGDAGDAF-DGFD--FGDDPSDKFFTSHNGMQFSTWDNDNDKF--
::.::... . : ::.:. :: . .:.. . .: :::: :::.: ::: .
NP_005 QNEANKYQISVNKYRG-TAGNALMDGASQLMGEN---RTMTIHNGMFFSTYDRDNDGWLT
370 380 390 400 410
350 360 370 380 390 400
pF1KB6 ---EGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSM
. .:...::.:::.:.:::.. :: :: :: :. . .: :.:..: .:: ::::
NP_005 SDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSM
420 430 440 450 460 470
410 420 430 440 450
pF1KB6 KKTTMKIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
.: .::: ::
NP_005 RKMSMKIRPFFPQQ
480 490
453 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:29:14 2016 done: Sat Nov 5 17:29:16 2016
Total Scan time: 7.270 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]