Result of FASTA (omim) for
pF1KB6630
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6630, 440 aa
1>>>pF1KB6630 440 - 440 aa - 440 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7655+/-0.000411; mu= 20.3577+/- 0.025
mean_var=75.3720+/-15.206, 0's: 0 Z-trim(113.1): 266 B-trim: 316 in 3/48
Lambda= 0.147730
statistics sampled from 21979 (22301) to 21979 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.261), width: 16
Scan time: 9.060
The best scores are: opt bits E(85289)
NP_002971 (OMIM: 182098) secretin receptor precurs ( 440) 3014 652.2 7.8e-187
XP_011509923 (OMIM: 182098) PREDICTED: secretin re ( 445) 2994 647.9 1.5e-185
XP_016860159 (OMIM: 182098) PREDICTED: secretin re ( 435) 2839 614.9 1.3e-175
XP_016860161 (OMIM: 182098) PREDICTED: secretin re ( 377) 2513 545.3 9.7e-155
XP_016860160 (OMIM: 182098) PREDICTED: secretin re ( 409) 2273 494.2 2.6e-139
XP_005263787 (OMIM: 182098) PREDICTED: secretin re ( 262) 1759 384.5 1.8e-106
XP_016860162 (OMIM: 182098) PREDICTED: secretin re ( 267) 1739 380.2 3.5e-105
XP_005265494 (OMIM: 192321) PREDICTED: vasoactive ( 456) 1448 318.4 2.4e-86
NP_004615 (OMIM: 192321) vasoactive intestinal pol ( 457) 1447 318.2 2.7e-86
NP_001238814 (OMIM: 192321) vasoactive intestinal ( 430) 1444 317.6 4.1e-86
NP_001186566 (OMIM: 102981) pituitary adenylate cy ( 447) 1437 316.1 1.2e-85
XP_011532381 (OMIM: 192321) PREDICTED: vasoactive ( 416) 1412 310.7 4.5e-84
NP_001238811 (OMIM: 192321) vasoactive intestinal ( 416) 1412 310.7 4.5e-84
XP_005265495 (OMIM: 192321) PREDICTED: vasoactive ( 416) 1412 310.7 4.5e-84
NP_001238813 (OMIM: 192321) vasoactive intestinal ( 409) 1405 309.2 1.3e-83
XP_005265496 (OMIM: 192321) PREDICTED: vasoactive ( 410) 1404 309.0 1.5e-83
NP_003373 (OMIM: 601970) vasoactive intestinal pol ( 438) 1328 292.8 1.2e-78
XP_005249618 (OMIM: 601970) PREDICTED: vasoactive ( 463) 1307 288.4 2.7e-77
XP_006716170 (OMIM: 601970) PREDICTED: vasoactive ( 455) 1298 286.5 9.9e-77
NP_001109 (OMIM: 102981) pituitary adenylate cycla ( 468) 1265 279.4 1.3e-74
XP_005249675 (OMIM: 102981) PREDICTED: pituitary a ( 411) 1264 279.2 1.4e-74
NP_000814 (OMIM: 139191,612781) growth hormone-rel ( 423) 1159 256.8 7.8e-68
XP_006716171 (OMIM: 601970) PREDICTED: vasoactive ( 392) 1136 251.9 2.2e-66
XP_011532382 (OMIM: 192321) PREDICTED: vasoactive ( 351) 1093 242.7 1.2e-63
XP_016867226 (OMIM: 102981) PREDICTED: pituitary a ( 475) 1087 241.5 3.5e-63
NP_001295188 (OMIM: 601970) vasoactive intestinal ( 422) 1054 234.4 4.3e-61
XP_011513565 (OMIM: 139191,612781) PREDICTED: grow ( 359) 1032 229.7 9.8e-60
XP_011514852 (OMIM: 601970) PREDICTED: vasoactive ( 439) 1024 228.1 3.7e-59
XP_016868069 (OMIM: 601970) PREDICTED: vasoactive ( 300) 1002 223.2 7.3e-58
NP_000155 (OMIM: 137241) gastric inhibitory polype ( 466) 984 219.6 1.4e-56
XP_016867225 (OMIM: 102981) PREDICTED: pituitary a ( 489) 915 204.9 3.9e-52
NP_001186565 (OMIM: 102981) pituitary adenylate cy ( 495) 915 204.9 3.9e-52
XP_006715708 (OMIM: 102981) PREDICTED: pituitary a ( 496) 915 204.9 3.9e-52
NP_001186564 (OMIM: 102981) pituitary adenylate cy ( 496) 915 204.9 3.9e-52
XP_016867227 (OMIM: 102981) PREDICTED: pituitary a ( 439) 914 204.6 4.2e-52
NP_001295347 (OMIM: 137241) gastric inhibitory pol ( 430) 904 202.5 1.8e-51
NP_001291451 (OMIM: 601970) vasoactive intestinal ( 358) 813 183.0 1.1e-45
XP_016879935 (OMIM: 125853,138033) PREDICTED: gluc ( 475) 742 168.0 4.8e-41
NP_001874 (OMIM: 602034) corticotropin-releasing f ( 411) 741 167.7 5e-41
NP_001189404 (OMIM: 602034) corticotropin-releasin ( 438) 740 167.5 6.1e-41
NP_001189410 (OMIM: 602034) corticotropin-releasin ( 397) 739 167.3 6.6e-41
XP_016867241 (OMIM: 602034) PREDICTED: corticotrop ( 397) 739 167.3 6.6e-41
XP_005265401 (OMIM: 125350,156400,168468,215045,60 ( 562) 734 166.4 1.8e-40
XP_016862422 (OMIM: 125350,156400,168468,215045,60 ( 593) 734 166.4 1.8e-40
NP_000307 (OMIM: 125350,156400,168468,215045,60000 ( 593) 734 166.4 1.8e-40
NP_001171673 (OMIM: 125350,156400,168468,215045,60 ( 593) 734 166.4 1.8e-40
XP_011532270 (OMIM: 125350,156400,168468,215045,60 ( 600) 734 166.4 1.9e-40
XP_016862421 (OMIM: 125350,156400,168468,215045,60 ( 606) 734 166.4 1.9e-40
XP_011532269 (OMIM: 125350,156400,168468,215045,60 ( 606) 734 166.4 1.9e-40
NP_001189411 (OMIM: 602034) corticotropin-releasin ( 410) 731 165.6 2.2e-40
>>NP_002971 (OMIM: 182098) secretin receptor precursor [ (440 aa)
initn: 3014 init1: 3014 opt: 3014 Z-score: 3475.3 bits: 652.2 E(85289): 7.8e-187
Smith-Waterman score: 3014; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KB6 MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 SPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFS
370 380 390 400 410 420
430 440
pF1KB6 NSTKASHLEQSQGTCRTSII
::::::::::::::::::::
NP_002 NSTKASHLEQSQGTCRTSII
430 440
>>XP_011509923 (OMIM: 182098) PREDICTED: secretin recept (445 aa)
initn: 1986 init1: 1986 opt: 2994 Z-score: 3452.2 bits: 647.9 E(85289): 1.5e-185
Smith-Waterman score: 2994; 98.9% identity (98.9% similar) in 445 aa overlap (1-440:1-445)
10 20 30 40 50 60
pF1KB6 MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL
190 200 210 220 230 240
250 260 270 280 290
pF1KB6 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGC-----WDINANASIW
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCPSLRCWDINANASIW
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 WIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHY
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB6 IVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHP
370 380 390 400 410 420
420 430 440
pF1KB6 VASFSNSTKASHLEQSQGTCRTSII
:::::::::::::::::::::::::
XP_011 VASFSNSTKASHLEQSQGTCRTSII
430 440
>>XP_016860159 (OMIM: 182098) PREDICTED: secretin recept (435 aa)
initn: 1831 init1: 1831 opt: 2839 Z-score: 3273.8 bits: 614.9 E(85289): 1.3e-175
Smith-Waterman score: 2839; 96.3% identity (97.7% similar) in 434 aa overlap (12-440:2-435)
10 20 30 40 50 60
pF1KB6 MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE
: .: .. . ..::::::::::::::::::::::::::::::::::::
XP_016 MLEFPETMGFSKNQTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL
180 190 200 210 220 230
250 260 270 280 290
pF1KB6 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGC-----WDINANASIW
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCPSLRCWDINANASIW
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 WIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHY
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB6 IVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHP
360 370 380 390 400 410
420 430 440
pF1KB6 VASFSNSTKASHLEQSQGTCRTSII
:::::::::::::::::::::::::
XP_016 VASFSNSTKASHLEQSQGTCRTSII
420 430
>>XP_016860161 (OMIM: 182098) PREDICTED: secretin recept (377 aa)
initn: 1505 init1: 1505 opt: 2513 Z-score: 2899.0 bits: 545.3 E(85289): 9.7e-155
Smith-Waterman score: 2513; 98.7% identity (98.7% similar) in 377 aa overlap (69-440:1-377)
40 50 60 70 80 90
pF1KB6 WEEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTS
::::::::::::::::::::::::::::::
XP_016 MWDNISCWPSSVPGRMVEVECPRFLRMLTS
10 20 30
100 110 120 130 140 150
pF1KB6 RNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB6 VALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLV
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB6 MVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARH
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB6 FLEDVGC-----WDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNE
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLEDVGCPSLRCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNE
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB6 VSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNG
280 290 300 310 320 330
400 410 420 430 440
pF1KB6 EVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLEQSQGTCRTSII
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLEQSQGTCRTSII
340 350 360 370
>>XP_016860160 (OMIM: 182098) PREDICTED: secretin recept (409 aa)
initn: 1481 init1: 1265 opt: 2273 Z-score: 2622.1 bits: 494.2 E(85289): 2.6e-139
Smith-Waterman score: 2637; 90.8% identity (90.8% similar) in 445 aa overlap (1-440:1-409)
10 20 30 40 50 60
pF1KB6 MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN
::::: :::::::::::::::::::
XP_016 QPVPG------------------------------------SLFRNCTQDGWSETFPRPN
70 80
130 140 150 160 170 180
pF1KB6 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB6 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL
150 160 170 180 190 200
250 260 270 280 290
pF1KB6 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGC-----WDINANASIW
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCPSLRCWDINANASIW
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB6 WIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHY
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB6 IVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHP
330 340 350 360 370 380
420 430 440
pF1KB6 VASFSNSTKASHLEQSQGTCRTSII
:::::::::::::::::::::::::
XP_016 VASFSNSTKASHLEQSQGTCRTSII
390 400
>>XP_005263787 (OMIM: 182098) PREDICTED: secretin recept (262 aa)
initn: 1759 init1: 1759 opt: 1759 Z-score: 2032.5 bits: 384.5 E(85289): 1.8e-106
Smith-Waterman score: 1759; 100.0% identity (100.0% similar) in 262 aa overlap (179-440:1-262)
150 160 170 180 190 200
pF1KB6 GYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYC
::::::::::::::::::::::::::::::
XP_005 MHLFVSFILRALSNFIKDAVLFSSDDVTYC
10 20 30
210 220 230 240 250 260
pF1KB6 DAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAI
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB6 FVALWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVALWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQE
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB6 TRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALGSFQGLVVAVLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALGSFQGLVVAVLY
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB6 CFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLEQSQGTCRTSII
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLEQSQGTCRTSII
220 230 240 250 260
>>XP_016860162 (OMIM: 182098) PREDICTED: secretin recept (267 aa)
initn: 1041 init1: 1041 opt: 1739 Z-score: 2009.4 bits: 380.2 E(85289): 3.5e-105
Smith-Waterman score: 1739; 98.1% identity (98.1% similar) in 267 aa overlap (179-440:1-267)
150 160 170 180 190 200
pF1KB6 GYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYC
::::::::::::::::::::::::::::::
XP_016 MHLFVSFILRALSNFIKDAVLFSSDDVTYC
10 20 30
210 220 230 240 250 260
pF1KB6 DAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAI
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB6 FVALWAIARHFLEDVGC-----WDINANASIWWIIRGPVILSILINFILFINILRILMRK
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 FVALWAIARHFLEDVGCPSLRCWDINANASIWWIIRGPVILSILINFILFINILRILMRK
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB6 LRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALGSFQGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALGSFQGLV
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB6 VAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLEQSQGTCRTSII
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLEQSQGTCRTSII
220 230 240 250 260
>>XP_005265494 (OMIM: 192321) PREDICTED: vasoactive inte (456 aa)
initn: 1402 init1: 867 opt: 1448 Z-score: 1671.3 bits: 318.4 E(85289): 2.4e-86
Smith-Waterman score: 1450; 49.2% identity (73.7% similar) in 457 aa overlap (1-438:1-447)
10 20 30 40 50
pF1KB6 MRPHLSPPLQQL-LLPVLLACAAHSTGA----LPRLCDVLQVLWEEQDQCLQELSREQTG
::: : . : .: :: : .:. : . :: .:.. .. :::.: .
XP_005 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQ-----
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 DLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNG-SLFRNCTQDGWSE
:. . :: ::::..:::.. :..: . :: ......: .: .. :.::..::..
XP_005 ---LENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 TFPRPN-LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCT
: : .:::.. . .: ... . ..:. ::.::. ::. :::: .:: ::.::::
XP_005 LEPGPYPIACGLDDKAASLDEQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 RNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWL
:::::::::.:::::: . :::: .::.: . :. .::: .::.::::.:::. ::
XP_005 RNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 LVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANAS
:::::::.::::.::::::::. :.. .::: :. :. .:.::: .:: :::: . :.:
XP_005 LVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWD-TINSS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 IWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGI
.::::.::.. :::.:::::: :.:::..::: . : .. : :.::::::::::::::.
XP_005 LWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB6 HYIVFAFSPED-AMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREF-
:::.::: :.. :... :::..:::::.:::.:::::::::: :...::..:::.
XP_005 HYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVL
360 370 380 390 400 410
420 430 440
pF1KB6 ---PL--HPVASFSN----STKASHLEQ-SQGTCRTSII
: :: .. :: ::..: : . : :. :.:
XP_005 GWNPKYRHPSGG-SNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
420 430 440 450
>>NP_004615 (OMIM: 192321) vasoactive intestinal polypep (457 aa)
initn: 1376 init1: 839 opt: 1447 Z-score: 1670.1 bits: 318.2 E(85289): 2.7e-86
Smith-Waterman score: 1449; 49.3% identity (73.8% similar) in 458 aa overlap (1-438:1-448)
10 20 30 40 50
pF1KB6 MRPHLSPPLQQL-LLPVLLACAAHSTGA----LPRLCDVLQVLWEEQDQCLQELSREQTG
::: : . : .: :: : .:. : . :: .:.. .. :::.: .
NP_004 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQ-----
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 DLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNG-SLFRNCTQDGWSE
:. . :: ::::..:::.. :..: . :: ......: .: .. :.::..::..
NP_004 ---LENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 TFPRPN-LACGVNVNDSS-NEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHC
: : .:::.. . .: .:.. . ..:. ::.::. ::. :::: .:: ::.:::
NP_004 LEPGPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 TRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSW
::::::::::.:::::: . :::: .::.: . :. .::: .::.::::.:::. :
NP_004 TRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFW
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 LLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANA
::::::::.::::.::::::::. :.. .::: :. :. .:.::: .:: :::: . :.
NP_004 LLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWD-TINS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 SIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFG
:.::::.::.. :::.:::::: :.:::..::: . : .. : :.::::::::::::::
NP_004 SLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFG
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB6 IHYIVFAFSPED-AMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREF
.:::.::: :.. :... :::..:::::.:::.:::::::::: :...::..:::.
NP_004 VHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGV
360 370 380 390 400 410
420 430 440
pF1KB6 ----PL--HPVASFSN----STKASHLEQ-SQGTCRTSII
: :: .. :: ::..: : . : :. :.:
NP_004 LGWNPKYRHPSGG-SNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
420 430 440 450
>>NP_001238814 (OMIM: 192321) vasoactive intestinal poly (430 aa)
initn: 1376 init1: 839 opt: 1444 Z-score: 1667.0 bits: 317.6 E(85289): 4.1e-86
Smith-Waterman score: 1446; 50.7% identity (75.9% similar) in 428 aa overlap (26-438:4-421)
10 20 30 40 50 60
pF1KB6 MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE
: : . :: .:.. .. :::.: . :
NP_001 MRAGRLQEECDYVQMIEVQHKQCLEEAQ--------LE
10 20 30
70 80 90 100 110
pF1KB6 QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNG-SLFRNCTQDGWSETFPRP
. . :: ::::..:::.. :..: . :: ......: .: .. :.::..::.. : :
NP_001 NETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGP
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB6 N-LACGVNVNDSS-NEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYI
.:::.. . .: .:.. . ..:. ::.::. ::. :::: .:: ::.::::::::
NP_001 YPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYI
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 HMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEG
:::::.:::::: . :::: .::.: . :. .::: .::.::::.:::. ::::::
NP_001 HMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 LYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWI
:::.::::.::::::::. :.. .::: :. :. .:.::: .:: :::: . :.:.:::
NP_001 LYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWD-TINSSLWWI
220 230 240 250 260
300 310 320 330 340 350
pF1KB6 IRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIV
:.::.. :::.:::::: :.:::..::: . : .. : :.::::::::::::::.:::.
NP_001 IKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIM
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB6 FAFSPED-AMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREF----P
::: :.. :... :::..:::::.:::.:::::::::: :...::..:::. :
NP_001 FAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNP
330 340 350 360 370 380
420 430 440
pF1KB6 L--HPVASFSN----STKASHLEQ-SQGTCRTSII
:: .. :: ::..: : . : :. :.:
NP_001 KYRHPSGG-SNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
390 400 410 420 430
440 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:37:17 2016 done: Sat Nov 5 11:37:18 2016
Total Scan time: 9.060 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]