Result of FASTA (omim) for
pF1KB6611
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6611, 412 aa
1>>>pF1KB6611 412 - 412 aa - 412 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8462+/-0.000365; mu= 20.4479+/- 0.023
mean_var=82.0725+/-16.085, 0's: 0 Z-trim(115.1): 241 B-trim: 66 in 1/53
Lambda= 0.141571
statistics sampled from 25008 (25266) to 25008 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.296), width: 16
Scan time: 7.160
The best scores are: opt bits E(85289)
NP_003164 (OMIM: 300254) histone-lysine N-methyltr ( 412) 2894 600.9 1.9e-171
NP_001269095 (OMIM: 300254) histone-lysine N-methy ( 423) 2870 596.0 5.7e-170
NP_001180353 (OMIM: 606503) histone-lysine N-methy ( 410) 1590 334.6 2.8e-91
XP_016872126 (OMIM: 606503) PREDICTED: histone-lys ( 350) 1398 295.3 1.6e-79
NP_001180354 (OMIM: 606503) histone-lysine N-methy ( 350) 1398 295.3 1.6e-79
XP_006717566 (OMIM: 606503) PREDICTED: histone-lys ( 350) 1398 295.3 1.6e-79
XP_011517964 (OMIM: 606503) PREDICTED: histone-lys ( 350) 1398 295.3 1.6e-79
NP_078946 (OMIM: 606503) histone-lysine N-methyltr ( 350) 1398 295.3 1.6e-79
XP_011517333 (OMIM: 607001,610253) PREDICTED: hist ( 488) 537 119.6 1.7e-26
XP_011517332 (OMIM: 607001,610253) PREDICTED: hist ( 559) 537 119.6 1.9e-26
XP_011517331 (OMIM: 607001,610253) PREDICTED: hist ( 775) 537 119.8 2.4e-26
NP_001180355 (OMIM: 606503) histone-lysine N-methy ( 230) 530 117.8 2.8e-26
XP_011517335 (OMIM: 607001,610253) PREDICTED: hist (1246) 537 120.0 3.3e-26
XP_011517328 (OMIM: 607001,610253) PREDICTED: hist (1253) 537 120.0 3.3e-26
XP_016870626 (OMIM: 607001,610253) PREDICTED: hist (1260) 537 120.0 3.3e-26
XP_016870627 (OMIM: 607001,610253) PREDICTED: hist (1260) 537 120.0 3.3e-26
XP_016870625 (OMIM: 607001,610253) PREDICTED: hist (1265) 537 120.0 3.3e-26
XP_011517327 (OMIM: 607001,610253) PREDICTED: hist (1267) 537 120.0 3.3e-26
XP_005266167 (OMIM: 607001,610253) PREDICTED: hist (1267) 537 120.0 3.3e-26
XP_011517326 (OMIM: 607001,610253) PREDICTED: hist (1275) 537 120.0 3.3e-26
XP_016870624 (OMIM: 607001,610253) PREDICTED: hist (1291) 537 120.0 3.4e-26
XP_006717351 (OMIM: 607001,610253) PREDICTED: hist (1292) 537 120.0 3.4e-26
XP_016870623 (OMIM: 607001,610253) PREDICTED: hist (1293) 537 120.0 3.4e-26
XP_011517325 (OMIM: 607001,610253) PREDICTED: hist (1294) 537 120.0 3.4e-26
XP_005266162 (OMIM: 607001,610253) PREDICTED: hist (1295) 537 120.0 3.4e-26
NP_079033 (OMIM: 607001,610253) histone-lysine N-m (1298) 537 120.0 3.4e-26
XP_011517324 (OMIM: 607001,610253) PREDICTED: hist (1300) 537 120.0 3.4e-26
XP_011517323 (OMIM: 607001,610253) PREDICTED: hist (1301) 537 120.0 3.4e-26
NP_001180356 (OMIM: 606503) histone-lysine N-methy ( 170) 526 116.9 4e-26
NP_001305762 (OMIM: 604599) histone-lysine N-methy (1008) 531 118.7 6.6e-26
NP_079532 (OMIM: 604599) histone-lysine N-methyltr (1176) 531 118.8 7.4e-26
XP_016865691 (OMIM: 604599) PREDICTED: histone-lys (1183) 531 118.8 7.4e-26
NP_006700 (OMIM: 604599) histone-lysine N-methyltr (1210) 531 118.8 7.5e-26
XP_006715039 (OMIM: 604599) PREDICTED: histone-lys (1217) 531 118.8 7.6e-26
NP_001276342 (OMIM: 604599) histone-lysine N-methy (1233) 531 118.8 7.6e-26
XP_006715038 (OMIM: 604599) PREDICTED: histone-lys (1240) 531 118.8 7.6e-26
XP_005248881 (OMIM: 604599) PREDICTED: histone-lys (1267) 531 118.8 7.8e-26
XP_006715037 (OMIM: 604599) PREDICTED: histone-lys (1274) 531 118.8 7.8e-26
NP_001263254 (OMIM: 609834) histone-lysine N-methy ( 365) 467 105.2 2.8e-22
NP_006506 (OMIM: 609834) histone-lysine N-methyltr ( 684) 467 105.4 4.4e-22
XP_016879841 (OMIM: 601674) PREDICTED: histone-lys ( 410) 347 80.7 7.4e-15
XP_016879840 (OMIM: 601674) PREDICTED: histone-lys ( 637) 347 80.9 1e-14
XP_016879839 (OMIM: 601674) PREDICTED: histone-lys ( 668) 347 80.9 1e-14
NP_001308011 (OMIM: 601674) histone-lysine N-methy ( 707) 347 80.9 1.1e-14
XP_005257202 (OMIM: 601674) PREDICTED: histone-lys ( 713) 347 80.9 1.1e-14
NP_001308010 (OMIM: 601674) histone-lysine N-methy ( 738) 347 81.0 1.1e-14
XP_011522819 (OMIM: 601674) PREDICTED: histone-lys ( 744) 347 81.0 1.1e-14
NP_001982 (OMIM: 601674) histone-lysine N-methyltr ( 747) 347 81.0 1.1e-14
NP_001308008 (OMIM: 601674) histone-lysine N-methy ( 753) 347 81.0 1.1e-14
XP_016867310 (OMIM: 277590,601573) PREDICTED: hist ( 637) 334 78.2 6.3e-14
>>NP_003164 (OMIM: 300254) histone-lysine N-methyltransf (412 aa)
initn: 2894 init1: 2894 opt: 2894 Z-score: 3199.2 bits: 600.9 E(85289): 1.9e-171
Smith-Waterman score: 2894; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KB6 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE
310 320 330 340 350 360
370 380 390 400 410
pF1KB6 LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
370 380 390 400 410
>>NP_001269095 (OMIM: 300254) histone-lysine N-methyltra (423 aa)
initn: 2870 init1: 2870 opt: 2870 Z-score: 3172.5 bits: 596.0 E(85289): 5.7e-170
Smith-Waterman score: 2870; 99.0% identity (99.5% similar) in 412 aa overlap (1-412:12-423)
10 20 30 40
pF1KB6 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLC
.:. : :::::::::::::::::::::::::::::::::::::::::::
NP_001 MVGMSRLRNDRLADPLTGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLC
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 DYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 LDPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB6 EGITLNQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGITLNQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB6 YDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB6 YDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK
370 380 390 400 410 420
410
pF1KB6 YLF
:::
NP_001 YLF
>>NP_001180353 (OMIM: 606503) histone-lysine N-methyltra (410 aa)
initn: 1620 init1: 925 opt: 1590 Z-score: 1759.8 bits: 334.6 E(85289): 2.8e-91
Smith-Waterman score: 1658; 59.3% identity (78.0% similar) in 410 aa overlap (8-411:13-409)
10 20 30 40 50
pF1KB6 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIR
: : : : . ::.::: ::.: ..::.:::: ..::::::::: ..
NP_001 MAAVGAEARGAWC-VPCLVSLDTLQELCRKEKLTCKSIGITKRNLNNYEVEYLCDYKVVK
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 EQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLR-RHHRSKTPRH----L
..:::::::.:.::: .:::: ::::: .:.:: .: . : . .. .. ::. :
NP_001 DMEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 DPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGE
:..:.:.:.::::: ::.::..::: ...: : : ::: :::.::: : :::::. .
NP_001 KPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAP
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 GITL-NQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCG
::.: :... :: : ::.. :::. . .::: . :... : :::::::::.::
NP_001 GISLVNEATFGCSCTDCFFQK---CCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 YDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQI
:::::.:::: .:.::::::..::::::.:: ::.. :::::::::.:::::::::::.
NP_001 PDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQF
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB6 YDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF
:: .: :::::::: : .::::: :::.::::::::::::::.:::::::: ::::::.
NP_001 YDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIAL
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK
:.:::: :::::::::.:. :. : .: . :. ::::: ::::. .::
NP_001 FSTRTINAGEELTFDYQMK-GSGDISSDSIDHS------PA--KKRVRTVCKCGAVTCRG
360 370 380 390 400
410
pF1KB6 YLF
::
NP_001 YLN
410
>>XP_016872126 (OMIM: 606503) PREDICTED: histone-lysine (350 aa)
initn: 1429 init1: 925 opt: 1398 Z-score: 1548.7 bits: 295.3 E(85289): 1.6e-79
Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349)
30 40 50 60 70 80
pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK
:::::::.:.::: .:::: ::::: .:.
XP_016 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ
10 20 30
90 100 110 120 130 140
pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL
:: .: . : . .. .. ::. : :..:.:.:.::::: ::.::..::: ...:
XP_016 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH
: : ::: :::.::: : :::::. . ::.: :... :: : ::.. :::. .
XP_016 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV
100 110 120 130 140
210 220 230 240 250 260
pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL
.::: . :... : :::::::::.:: :::::.:::: .:.::::::..::::::.::
XP_016 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF
::.. :::::::::.:::::::::::.:: .: :::::::: : .::::: :::.:::
XP_016 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS
:::::::::::.:::::::: ::::::.:.:::: :::::::::.:. . :. : .:
XP_016 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH
270 280 290 300 310 320
390 400 410
pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF
. :. ::::: ::::. .:: ::
XP_016 S------PA--KKRVRTVCKCGAVTCRGYLN
330 340 350
>>NP_001180354 (OMIM: 606503) histone-lysine N-methyltra (350 aa)
initn: 1429 init1: 925 opt: 1398 Z-score: 1548.7 bits: 295.3 E(85289): 1.6e-79
Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349)
30 40 50 60 70 80
pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK
:::::::.:.::: .:::: ::::: .:.
NP_001 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ
10 20 30
90 100 110 120 130 140
pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL
:: .: . : . .. .. ::. : :..:.:.:.::::: ::.::..::: ...:
NP_001 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH
: : ::: :::.::: : :::::. . ::.: :... :: : ::.. :::. .
NP_001 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV
100 110 120 130 140
210 220 230 240 250 260
pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL
.::: . :... : :::::::::.:: :::::.:::: .:.::::::..::::::.::
NP_001 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF
::.. :::::::::.:::::::::::.:: .: :::::::: : .::::: :::.:::
NP_001 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS
:::::::::::.:::::::: ::::::.:.:::: :::::::::.:. . :. : .:
NP_001 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH
270 280 290 300 310 320
390 400 410
pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF
. :. ::::: ::::. .:: ::
NP_001 S------PA--KKRVRTVCKCGAVTCRGYLN
330 340 350
>>XP_006717566 (OMIM: 606503) PREDICTED: histone-lysine (350 aa)
initn: 1429 init1: 925 opt: 1398 Z-score: 1548.7 bits: 295.3 E(85289): 1.6e-79
Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349)
30 40 50 60 70 80
pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK
:::::::.:.::: .:::: ::::: .:.
XP_006 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ
10 20 30
90 100 110 120 130 140
pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL
:: .: . : . .. .. ::. : :..:.:.:.::::: ::.::..::: ...:
XP_006 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH
: : ::: :::.::: : :::::. . ::.: :... :: : ::.. :::. .
XP_006 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV
100 110 120 130 140
210 220 230 240 250 260
pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL
.::: . :... : :::::::::.:: :::::.:::: .:.::::::..::::::.::
XP_006 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF
::.. :::::::::.:::::::::::.:: .: :::::::: : .::::: :::.:::
XP_006 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS
:::::::::::.:::::::: ::::::.:.:::: :::::::::.:. . :. : .:
XP_006 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH
270 280 290 300 310 320
390 400 410
pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF
. :. ::::: ::::. .:: ::
XP_006 S------PA--KKRVRTVCKCGAVTCRGYLN
330 340 350
>>XP_011517964 (OMIM: 606503) PREDICTED: histone-lysine (350 aa)
initn: 1429 init1: 925 opt: 1398 Z-score: 1548.7 bits: 295.3 E(85289): 1.6e-79
Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349)
30 40 50 60 70 80
pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK
:::::::.:.::: .:::: ::::: .:.
XP_011 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ
10 20 30
90 100 110 120 130 140
pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL
:: .: . : . .. .. ::. : :..:.:.:.::::: ::.::..::: ...:
XP_011 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH
: : ::: :::.::: : :::::. . ::.: :... :: : ::.. :::. .
XP_011 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV
100 110 120 130 140
210 220 230 240 250 260
pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL
.::: . :... : :::::::::.:: :::::.:::: .:.::::::..::::::.::
XP_011 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF
::.. :::::::::.:::::::::::.:: .: :::::::: : .::::: :::.:::
XP_011 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS
:::::::::::.:::::::: ::::::.:.:::: :::::::::.:. . :. : .:
XP_011 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH
270 280 290 300 310 320
390 400 410
pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF
. :. ::::: ::::. .:: ::
XP_011 S------PA--KKRVRTVCKCGAVTCRGYLN
330 340 350
>>NP_078946 (OMIM: 606503) histone-lysine N-methyltransf (350 aa)
initn: 1429 init1: 925 opt: 1398 Z-score: 1548.7 bits: 295.3 E(85289): 1.6e-79
Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349)
30 40 50 60 70 80
pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK
:::::::.:.::: .:::: ::::: .:.
NP_078 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ
10 20 30
90 100 110 120 130 140
pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL
:: .: . : . .. .. ::. : :..:.:.:.::::: ::.::..::: ...:
NP_078 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH
: : ::: :::.::: : :::::. . ::.: :... :: : ::.. :::. .
NP_078 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV
100 110 120 130 140
210 220 230 240 250 260
pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL
.::: . :... : :::::::::.:: :::::.:::: .:.::::::..::::::.::
NP_078 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF
::.. :::::::::.:::::::::::.:: .: :::::::: : .::::: :::.:::
NP_078 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS
:::::::::::.:::::::: ::::::.:.:::: :::::::::.:. . :. : .:
NP_078 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH
270 280 290 300 310 320
390 400 410
pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF
. :. ::::: ::::. .:: ::
NP_078 S------PA--KKRVRTVCKCGAVTCRGYLN
330 340 350
>>XP_011517333 (OMIM: 607001,610253) PREDICTED: histone- (488 aa)
initn: 583 init1: 255 opt: 537 Z-score: 596.6 bits: 119.6 E(85289): 1.7e-26
Smith-Waterman score: 537; 41.2% identity (64.6% similar) in 226 aa overlap (149-365:217-432)
120 130 140 150 160 170
pF1KB6 VQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVA
: :: . : . :... : .....
XP_011 DSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNI
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB6 VG---CEC-QDCLWAPTGGCCPGASLHKFAYNDQGQV--RLRAGLP--IYECNSRCRCGY
. : : .:: ...: : . :. .:.. .. . : :.::: : :
XP_011 THLQYCVCIDDC---SSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWR
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB6 DCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIY
.: :::::.:.: : ..:: : :::::.:. : ..:: :::::.:.. ::. : .
XP_011 NCRNRVVQNGLRARLQLYRTRD-MGWGVRSLQDIPPGTFVCEYVGELISDSEADVREE--
310 320 330 340 350 360
300 310 320 330 340
pF1KB6 DRQGATYLFDLDYVE-DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF
: .:::::: . .:: .:: .:::.:.:.:: :.::: ::. . : :.:::::
XP_011 D----SYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAF
370 380 390 400 410
350 360 370 380 390 400
pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK
:.:: :.:::.: :::
XP_011 FSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHSSAALAQRQASAAQEAQEDGL
420 430 440 450 460 470
>>XP_011517332 (OMIM: 607001,610253) PREDICTED: histone- (559 aa)
initn: 583 init1: 255 opt: 537 Z-score: 595.8 bits: 119.6 E(85289): 1.9e-26
Smith-Waterman score: 537; 41.2% identity (64.6% similar) in 226 aa overlap (149-365:288-503)
120 130 140 150 160 170
pF1KB6 VQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVA
: :: . : . :... : .....
XP_011 DSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNI
260 270 280 290 300 310
180 190 200 210 220 230
pF1KB6 VG---CEC-QDCLWAPTGGCCPGASLHKFAYNDQGQV--RLRAGLP--IYECNSRCRCGY
. : : .:: ...: : . :. .:.. .. . : :.::: : :
XP_011 THLQYCVCIDDC---SSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWR
320 330 340 350 360 370
240 250 260 270 280 290
pF1KB6 DCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIY
.: :::::.:.: : ..:: : :::::.:. : ..:: :::::.:.. ::. : .
XP_011 NCRNRVVQNGLRARLQLYRTRD-MGWGVRSLQDIPPGTFVCEYVGELISDSEADVREE--
380 390 400 410 420 430
300 310 320 330 340
pF1KB6 DRQGATYLFDLDYVE-DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF
: .:::::: . .:: .:: .:::.:.:.:: :.::: ::. . : :.:::::
XP_011 D----SYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAF
440 450 460 470 480
350 360 370 380 390 400
pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK
:.:: :.:::.: :::
XP_011 FSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHSSAALAQRQASAAQEAQEDGL
490 500 510 520 530 540
412 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:05:00 2016 done: Sat Nov 5 11:05:01 2016
Total Scan time: 7.160 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]