Result of FASTA (ccds) for
pF1KB6608
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6608, 431 aa
1>>>pF1KB6608 431 - 431 aa - 431 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6708+/-0.000983; mu= 15.7914+/- 0.059
mean_var=102.9233+/-19.363, 0's: 0 Z-trim(107.9): 190 B-trim: 22 in 2/48
Lambda= 0.126420
statistics sampled from 9659 (9875) to 9659 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.303), width: 16
Scan time: 2.910
The best scores are: opt bits E(32554)
CCDS7339.1 PLAU gene_id:5328|Hs108|chr10 ( 431) 3066 570.1 1.5e-162
CCDS44442.1 PLAU gene_id:5328|Hs108|chr10 ( 414) 2886 537.3 1.1e-152
CCDS3369.1 HGFAC gene_id:3083|Hs108|chr4 ( 655) 982 190.2 5.2e-48
CCDS34302.1 F12 gene_id:2161|Hs108|chr5 ( 615) 676 134.3 3.1e-31
CCDS75098.1 HGFAC gene_id:3083|Hs108|chr4 ( 662) 659 131.3 2.8e-30
CCDS3709.1 PRSS12 gene_id:8492|Hs108|chr4 ( 875) 623 124.8 3.3e-28
CCDS83291.1 PLAT gene_id:5327|Hs108|chr8 ( 473) 619 123.8 3.5e-28
CCDS42110.1 PRSS33 gene_id:260429|Hs108|chr16 ( 280) 599 120.0 3e-27
CCDS12088.1 TMPRSS9 gene_id:360200|Hs108|chr19 (1059) 550 111.6 3.8e-24
CCDS45469.1 PRSS8 gene_id:5652|Hs108|chr16 ( 343) 541 109.5 5.3e-24
CCDS32993.1 HPN gene_id:3249|Hs108|chr19 ( 417) 534 108.3 1.5e-23
CCDS58452.1 PRSS36 gene_id:146547|Hs108|chr16 ( 752) 520 106.0 1.3e-22
CCDS58453.1 PRSS36 gene_id:146547|Hs108|chr16 ( 850) 520 106.0 1.4e-22
CCDS32436.1 PRSS36 gene_id:146547|Hs108|chr16 ( 855) 520 106.0 1.5e-22
CCDS34120.1 KLKB1 gene_id:3818|Hs108|chr4 ( 638) 515 105.0 2.2e-22
CCDS55788.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 532) 498 101.8 1.7e-21
CCDS58185.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 563) 498 101.8 1.7e-21
CCDS41721.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 567) 498 101.8 1.7e-21
CCDS73391.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 413) 491 100.4 3.4e-21
CCDS73392.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 448) 491 100.5 3.6e-21
CCDS44735.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 457) 491 100.5 3.6e-21
CCDS10430.1 TPSG1 gene_id:25823|Hs108|chr16 ( 321) 487 99.6 4.7e-21
CCDS8487.1 ST14 gene_id:6768|Hs108|chr11 ( 855) 486 99.8 1.1e-20
CCDS10431.1 TPSAB1 gene_id:7177|Hs108|chr16 ( 275) 477 97.7 1.5e-20
CCDS10481.1 PRSS22 gene_id:64063|Hs108|chr16 ( 317) 476 97.6 1.9e-20
CCDS30605.1 CELA2B gene_id:51032|Hs108|chr1 ( 269) 474 97.2 2.1e-20
CCDS2145.1 PROC gene_id:5624|Hs108|chr2 ( 461) 476 97.7 2.4e-20
CCDS13686.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 454) 475 97.6 2.7e-20
CCDS3518.1 TMPRSS11D gene_id:9407|Hs108|chr4 ( 418) 468 96.2 6.2e-20
CCDS3847.1 F11 gene_id:2160|Hs108|chr4 ( 625) 467 96.2 9.4e-20
CCDS10476.1 PRSS27 gene_id:83886|Hs108|chr16 ( 290) 457 94.1 1.9e-19
CCDS14101.1 ACR gene_id:49|Hs108|chr22 ( 421) 455 93.9 3.2e-19
CCDS73602.1 F7 gene_id:2155|Hs108|chr13 ( 382) 452 93.3 4.4e-19
CCDS43129.2 TMPRSS7 gene_id:344805|Hs108|chr3 ( 717) 455 94.1 4.8e-19
CCDS9529.1 F7 gene_id:2155|Hs108|chr13 ( 444) 452 93.4 4.9e-19
CCDS9528.1 F7 gene_id:2155|Hs108|chr13 ( 466) 452 93.4 5.1e-19
CCDS219.1 CELA3B gene_id:23436|Hs108|chr1 ( 270) 447 92.2 6.5e-19
CCDS6126.1 PLAT gene_id:5327|Hs108|chr8 ( 562) 451 93.3 6.6e-19
CCDS10478.1 PRSS21 gene_id:10942|Hs108|chr16 ( 314) 444 91.8 1.1e-18
CCDS44881.1 TMPRSS12 gene_id:283471|Hs108|chr12 ( 348) 444 91.8 1.1e-18
CCDS157.1 CELA2A gene_id:63036|Hs108|chr1 ( 269) 442 91.3 1.2e-18
CCDS6127.1 PLAT gene_id:5327|Hs108|chr8 ( 516) 441 91.4 2.2e-18
CCDS220.1 CELA3A gene_id:10136|Hs108|chr1 ( 270) 437 90.4 2.3e-18
CCDS73251.1 OVCH2 gene_id:341277|Hs108|chr11 ( 565) 439 91.1 3e-18
CCDS12822.1 KLK13 gene_id:26085|Hs108|chr19 ( 277) 434 89.9 3.4e-18
CCDS156.1 CTRC gene_id:11330|Hs108|chr1 ( 268) 433 89.7 3.8e-18
CCDS33564.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 492) 424 88.3 1.8e-17
CCDS54486.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 529) 424 88.3 1.9e-17
CCDS12808.1 KLK2 gene_id:3817|Hs108|chr19 ( 261) 419 87.1 2.2e-17
CCDS12804.1 KLK1 gene_id:3816|Hs108|chr19 ( 262) 419 87.1 2.2e-17
>>CCDS7339.1 PLAU gene_id:5328|Hs108|chr10 (431 aa)
initn: 3066 init1: 3066 opt: 3066 Z-score: 3032.0 bits: 570.1 E(32554): 1.5e-162
Smith-Waterman score: 3066; 99.8% identity (99.8% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KB6 MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 YCRNPDNRRRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
CCDS73 YCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
370 380 390 400 410 420
430
pF1KB6 SHTKEENGLAL
:::::::::::
CCDS73 SHTKEENGLAL
430
>>CCDS44442.1 PLAU gene_id:5328|Hs108|chr10 (414 aa)
initn: 2886 init1: 2886 opt: 2886 Z-score: 2854.8 bits: 537.3 E(32554): 1.1e-152
Smith-Waterman score: 2886; 99.5% identity (99.8% similar) in 403 aa overlap (29-431:12-414)
10 20 30 40 50 60
pF1KB6 MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
.:::::::::::::::::::::::::::::::
CCDS44 MVFHLRTRYEQANCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
10 20 30 40
70 80 90 100 110 120
pF1KB6 HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 YCRNPDNRRRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
CCDS44 YCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
350 360 370 380 390 400
430
pF1KB6 SHTKEENGLAL
:::::::::::
CCDS44 SHTKEENGLAL
410
>>CCDS3369.1 HGFAC gene_id:3083|Hs108|chr4 (655 aa)
initn: 988 init1: 416 opt: 982 Z-score: 975.4 bits: 190.2 E(32554): 5.2e-48
Smith-Waterman score: 986; 38.7% identity (61.8% similar) in 419 aa overlap (25-424:242-646)
10 20 30 40 50
pF1KB6 MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCP
: . . ::::::: .. : ::
CCDS33 EGGDRWARVRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTC-HLIVATGTTVCACP
220 230 240 250 260 270
60 70 80 90 100 110
pF1KB6 KKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQL
:.:. :.:. .. :. ::: ::: :::.. : :: ::: . :. . . : :
CCDS33 PGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALL
280 290 300 310 320 330
120 130 140 150 160
pF1KB6 GLGKHNYCRNPDNRRRPWCYVQVGLKPLVQE-CMVHDC-------------ADGKKPSSP
::: : ::::::: .:::::: : . : : : .. : : .:.::
CCDS33 GLGPHAYCRNPDNDERPWCYV-VKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASP
340 350 360 370 380
170 180 190 200 210
pF1KB6 PEELKFQCGQKT-----LRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLIS
.. ::.. :::: :::: . ..::.:::: : : :.:::.
CCDS33 GRQ---ACGRRHKKRTFLRPR--IIGGSSSLPGSHPWLAAIYI---GDSF---CAGSLVH
390 400 410 420 430
220 230 240 250 260 270
pF1KB6 PCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHND
:::.::.::: : ... : ::. .: .:. . : .:. : . ::. . . : :
CCDS33 TCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDH-D
440 450 460 470 480 490
280 290 300 310 320 330
pF1KB6 IALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMT
..:.....: ::: :. .: :::: . : .:.:.:.:. . . : .:. .
CCDS33 LVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREA
500 510 520 530 540 550
340 350 360 370 380 390
pF1KB6 VVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVS
.: :.. ..:..:. ::.... .::::. . :.:.:::::::::.: .: : ::.:
CCDS33 LVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIIS
560 570 580 590 600 610
400 410 420 430
pF1KB6 WGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
:: ::. ::::::::.... :: .. .
CCDS33 WGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS
620 630 640 650
>>CCDS34302.1 F12 gene_id:2161|Hs108|chr5 (615 aa)
initn: 955 init1: 260 opt: 676 Z-score: 674.2 bits: 134.3 E(32554): 3.1e-31
Smith-Waterman score: 896; 35.2% identity (54.7% similar) in 446 aa overlap (33-423:183-613)
10 20 30 40 50 60
pF1KB6 ALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHC
::.:: :. . . :.:: . : :
CCDS34 TEQAAVARCQCKGPDAHCQRLASQACRTNPCLHGGRCLE---VEGHRLCHCPVGYTGAFC
160 170 180 190 200
70 80 90 100 110 120
pF1KB6 EIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSD-ALQLGLGKHNY
..: . .::.: : ::: : : : :: :: : . ::. .. : . ::: : .
CCDS34 DVDTKASCYDGRGLSYRGLARTTLSGAPCQPWAS----EATYRNVTAEQARNWGLGGHAF
210 220 230 240 250 260
130 140 150 160
pF1KB6 CRNPDNRRRPWCYVQVGLKPLVQECMVHDC-----ADGKKPSSP----------PEELKF
:::::: ::::.: . . : . .: : : :: : :
CCDS34 CRNPDNDIRPWCFVLNRDRLSWEYCDLAQCQTPTQAAPPTPVSPRLHVPLMPAQPAPPKP
270 280 290 300 310 320
170 180 190
pF1KB6 Q--------------------------------CGQ---KTLRPRFKIIGGEFTTIENQP
: ::: :.: ...:: . .:
CCDS34 QPTTRTPPQSQTPGALPAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHP
330 340 350 360 370 380
200 210 220 230 240 250
pF1KB6 WFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGE
..::.: : :.::::.::::..:.::. : : :: : ::. : : . .
CCDS34 YIAALYWGHS------FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHSCEPC
390 400 410 420 430
260 270 280 290 300 310
pF1KB6 MKFEVENLILHKDYSADTLAHHNDIALLKIR-SKEGRCAQPSRTIQTICLPSMYNDPQFG
. . :.. ::. .: .....:.:::... . .: :: : .: .:::: :.
CCDS34 QTLAVRSYRLHEAFSP--VSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSGAARPSET
440 450 460 470 480 490
320 330 340 350 360 370
pF1KB6 TSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTD
: :...:.:.. : :. . : ..: ..:. : .:: . ::::. . ::
CCDS34 TLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTD
500 510 520 530 540 550
380 390 400 410 420
pF1KB6 SCQGDSGGPLVCSLQG---RMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEEN
.::::::::::: :. :.:: ::.::: ::. ..:::::: :...: ::: ::
CCDS34 ACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWIREHTVS
560 570 580 590 600 610
430
pF1KB6 GLAL
>>CCDS75098.1 HGFAC gene_id:3083|Hs108|chr4 (662 aa)
initn: 988 init1: 416 opt: 659 Z-score: 657.0 bits: 131.3 E(32554): 2.8e-30
Smith-Waterman score: 976; 38.0% identity (61.5% similar) in 426 aa overlap (25-424:242-653)
10 20 30 40 50
pF1KB6 MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCP
: . . ::::::: .. : ::
CCDS75 EGGDRWARVRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTC-HLIVATGTTVCACP
220 230 240 250 260 270
60 70 80 90 100 110
pF1KB6 KKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQL
:.:. :.:. .. :. ::: ::: :::.. : :: ::: . :. . . : :
CCDS75 PGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALL
280 290 300 310 320 330
120 130 140 150
pF1KB6 GLGKHNYCRNPDNRRRPWCYVQVGLKPLVQE-CMVHDC---ADGKK--------------
::: : ::::::: .:::::: : . : : : .. : ..:..
CCDS75 GLGPHAYCRNPDNDERPWCYV-VKDSALSWEYCRLEACDLETEGRESLTRVQLSPDLLAT
340 350 360 370 380
160 170 180 190 200
pF1KB6 ---PSSPPEELKFQCGQKT-----LRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYV
:.:: .. ::.. :::: :::: . ..::.:::: : :
CCDS75 LPEPASPGRQ---ACGRRHKKRTFLRPR--IIGGSSSLPGSHPWLAAIYI---GDSF---
390 400 410 420 430
210 220 230 240 250 260
pF1KB6 CGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSAD
:.:::. :::.::.::: : ... : ::. .: .:. . : .:. : . ::.
CCDS75 CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVF
440 450 460 470 480 490
270 280 290 300 310 320
pF1KB6 TLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLY
. . : :..:.....: ::: :. .: :::: . : .:.:.:.:. . . :
CCDS75 NPSDH-DLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGY
500 510 520 530 540 550
330 340 350 360 370 380
pF1KB6 PEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRM
.:. ..: :.. ..:..:. ::.... .::::. . :.:.:::::::::.: .:
CCDS75 SSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVA
560 570 580 590 600 610
390 400 410 420 430
pF1KB6 TLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
: ::.::: ::. ::::::::.... :: .. .
CCDS75 YLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS
620 630 640 650 660
>>CCDS3709.1 PRSS12 gene_id:8492|Hs108|chr4 (875 aa)
initn: 568 init1: 176 opt: 623 Z-score: 620.0 bits: 124.8 E(32554): 3.3e-28
Smith-Waterman score: 628; 33.5% identity (60.1% similar) in 358 aa overlap (78-424:543-874)
50 60 70 80 90 100
pF1KB6 IHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTM---GRPCLPWNSATVLQQTY
:.: : . :: :. : . .:
CCDS37 VEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGN
520 530 540 550 560 570
110 120 130 140 150 160
pF1KB6 HAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPLVQECMVHDCADGKKPS--SPPE
. .: .. .:.:: ::. .. .:. : ::: : : :
CCDS37 ERSLADCIKQDIGRHN-CRHSED---------AGVI-----CDYF----GKKASGNSNKE
580 590 600 610
170 180 190 200 210 220
pF1KB6 ELKFQCGQKTLRPRFK-IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVIS
:. :: . :. : : ::::. . . :: ... . :. .::..:.: :::..
CCDS37 SLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLT
620 630 640 650 660 670
230 240 250 260 270 280
pF1KB6 ATHCFIDYPKK-EDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLK
:.::: : .. ..: : .: . . : .. :.....:..: : . ::::..
CCDS37 AAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDY--DIALVR
680 690 700 710 720 730
290 300 310 320 330
pF1KB6 IRSKEGRCAQPSRTIQTICLPSMYNDPQ-FGTSCEITGFGKENSTDYLYPEQLKMTVVKL
... : .::. : . ::: . :: ...: :::.: .: : . :..... :
CCDS37 LQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWG---DTGRAYSRTLQQAAIPL
740 750 760 770 780
340 350 360 370 380 390
pF1KB6 ISHRECQQPHYYGSEVTTKMLCAAD--PQWKTDSCQGDSGGPLVCSLQGR-MTLTGIVSW
. .: :.. : .. : .::::.. . ..:::::::::::.: :. .. :..::
CCDS37 LPKRFCEE--RYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSW
790 800 810 820 830 840
400 410 420 430
pF1KB6 GRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
: ::..::.:::::.:: :.:::.: ::
CCDS37 GYGCGVKDSPGVYTKVSAFVPWIKSVTKL
850 860 870
>>CCDS83291.1 PLAT gene_id:5327|Hs108|chr8 (473 aa)
initn: 1153 init1: 276 opt: 619 Z-score: 619.5 bits: 123.8 E(32554): 3.5e-28
Smith-Waterman score: 1178; 43.3% identity (66.4% similar) in 420 aa overlap (18-424:72-472)
10 20 30 40
pF1KB6 MRALLARLLLCVLVVSDSKGSNELHQVP-SNCD---CLNGGTCVSNK
..: . :.:: ..:. :.::::: .
CCDS83 RDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQAL
50 60 70 80 90 100
50 60 70 80 90 100
pF1KB6 YFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQT
:::.. :.::. :.:. ::: .: :: ::: ::: : : :::::: .. ..
CCDS83 YFSDF-VCQCPEGFAGKCCEIGNSD-CYFGNGSAYRGTHSLTESGASCLPWNSMILIGKV
110 120 130 140 150
110 120 130 140 150 160
pF1KB6 YHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEE
: :. .: :::::::::::::. .:::.: . . . : : .:.
CCDS83 YTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCST----------
160 170 180 190 200
170 180 190 200 210 220
pF1KB6 LKFQCGQKTL-RPRFKIIGGEFTTIENQPWFAAIYRRHR-GGSVTYVCGGSLISPCWVIS
:: . .:.:.: :: :. : ..:: :::. .:: . . ..::: ::: ::..:
CCDS83 ----CGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILS
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB6 ATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKI
:.::: . . : :::. . :.:::::. :.::... :: . ::::::..
CCDS83 AAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDT--YDNDIALLQL
270 280 290 300 310 320
290 300 310 320 330 340
pF1KB6 RSKEGRCAQPSRTIQTICLPSM-YNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLI
.: .:::: : ...:.::: . :.. : ::..:.::... . .: :.:: . :.:
CCDS83 KSDSSRCAQESSVVRTVCLPPADLQLPDW-TECELSGYGKHEALSPFYSERLKEAHVRLY
330 340 350 360 370 380
350 360 370 380 390
pF1KB6 SHRECQQPHYYGSEVTTKMLCAAD-----PQWKT-DSCQGDSGGPLVCSLQGRMTLTGIV
.: . : . :: .::::.: :: . :.::::::::::: .:::::.::.
CCDS83 PSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGII
390 400 410 420 430 440
400 410 420 430
pF1KB6 SWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
::: ::. :: :::::.:...: :::.. .
CCDS83 SWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP
450 460 470
>>CCDS42110.1 PRSS33 gene_id:260429|Hs108|chr16 (280 aa)
initn: 550 init1: 288 opt: 599 Z-score: 602.7 bits: 120.0 E(32554): 3e-27
Smith-Waterman score: 605; 39.9% identity (62.0% similar) in 263 aa overlap (168-421:28-276)
140 150 160 170 180 190
pF1KB6 GLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIY
::: . : :.::. . :: :.:
CCDS42 MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSR--IVGGRDGRDGEWPWQASI-
10 20 30 40 50
200 210 220 230 240 250
pF1KB6 RRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVE
.:::. .:::::::.: ::..:.::: .: : :: ::.:.. .. :.
CCDS42 -QHRGA---HVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVR
60 70 80 90 100 110
260 270 280 290 300 310
pF1KB6 NLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITG
..: ::: : . ..:.:::..: : . : .: .::: : :: :..::
CCDS42 RVLLPPDYSED--GARGDLALLQLR----RPVPLSARVQPVCLPVPGARPPPGTPCRVTG
120 130 140 150 160
320 330 340 350 360
pF1KB6 FGKENSTDYLYPEQ--LKMTVVKLISHRECQQPHYYGSEVTTKM-------LCAADPQWK
.:. : :: :. . : :.. : :. .. :..: :::. :: .
CCDS42 WGSLRPGVPL-PEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGH
170 180 190 200 210 220
370 380 390 400 410 420
pF1KB6 TDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENG
:.:::::::::.: .: .:.:.::::.:::: ..::::: :. . :::..
CCDS42 KDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
230 240 250 260 270 280
430
pF1KB6 LAL
>>CCDS12088.1 TMPRSS9 gene_id:360200|Hs108|chr19 (1059 aa)
initn: 558 init1: 158 opt: 550 Z-score: 546.9 bits: 111.6 E(32554): 3.8e-24
Smith-Waterman score: 550; 35.4% identity (63.2% similar) in 288 aa overlap (150-430:173-443)
120 130 140 150 160 170
pF1KB6 NYCRNPDNRRRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCG-QKTLRPRFK
.: : . :. .: . .:: : . : .
CCDS12 PLAERDFKSGRCPGNSFSCGNSQCVTKVNPECDDQEDCSDGSDEAHCECGLQPAWRMAGR
150 160 170 180 190 200
180 190 200 210 220 230
pF1KB6 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVY
:.:: .. . :: :.. :... . ::...:. :..::.::: .. ...:
CCDS12 IVGGMEASPGEFPWQASL-RENK----EHFCGAAIINARWLVSAAHCFNEFQDPTKWVAY
210 220 230 240 250
240 250 260 270 280 290
pF1KB6 LGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQP-SRTIQT
.: . :... . .. .: ... : :.::: :.:.:.. : : .: ::
CCDS12 VGATYLSGSEASTVRAQVVQIVKHPLYNADTADF--DVAVLELTSP-----LPFGRHIQP
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB6 ICLPSMYNDPQFGTSCEITGFG--KENSTDYLY-PEQLKMTVVKLISHRECQQPHYYGSE
.:::. . . .: :.:.: :: :.: :: :. ..:.:... : . ::
CCDS12 VCLPAATHIFPPSKKCLISGWGYLKE---DFLVKPEVLQKATVELLDQALCAS--LYGHS
320 330 340 350 360
360 370 380 390 400 410
pF1KB6 VTTKMLCAADPQWKTDSCQGDSGGPLVCSL-QGRMTLTGIVSWGRGCALKDKPGVYTRVS
.: .:.::. . :.::::::::::::: .::. :.:::::: ::: .::::.::.
CCDS12 LTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVT
370 380 390 400 410 420
420 430
pF1KB6 HFLPWI-RSHTKEENGLAL
.. :: .. :: ::
CCDS12 RLRDWILEATTKASMPLAPTMAPAPAAPSTAWPTSPESPVVSTPTKSMQALSTVPLDWVT
430 440 450 460 470 480
>--
initn: 536 init1: 150 opt: 532 Z-score: 529.2 bits: 108.3 E(32554): 3.7e-23
Smith-Waterman score: 532; 35.0% identity (62.8% similar) in 274 aa overlap (157-425:803-1059)
130 140 150 160 170 180
pF1KB6 NRRRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPR--FKIIGGEF
:..: . : . : : .:.::
CCDS12 TPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAPAALTRIVGGSA
780 790 800 810 820 830
190 200 210 220 230 240
pF1KB6 TTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRL
. . :: .... :.: . ::. :.. :..::.::: : ... ..:: :
CCDS12 AGRGEWPWQVSLWLRRR----EHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFL
840 850 860 870 880
250 260 270 280 290 300
pF1KB6 NSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMY
:...:... .: . : :. :: . :.:::.. . : :: .. ::::
CCDS12 -SGAEGQLE-RVARIYKHPFYNLYTLDY--DVALLELAGPVRR----SRLVRPICLPEPA
890 900 910 920 930 940
310 320 330 340 350 360
pF1KB6 NDPQFGTSCEITGFG--KENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCA
: :: : :::.: .:... . .::. ..:.:.:.. :.. .: .....::::
CCDS12 PRPPDGTRCVITGWGSVREGGS---MARQLQKAAVRLLSEQTCRR--FYPVQISSRMLCA
950 960 970 980 990
370 380 390 400 410 420
pF1KB6 ADPQWKTDSCQGDSGGPLVCSL-QGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRS
. :: .:::.::.::::.: .:: .:::..::: ::. :::::::. :: .
CCDS12 GFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQ
1000 1010 1020 1030 1040 1050
430
pF1KB6 HTKEENGLAL
: .:
CCDS12 HIQE
>--
initn: 422 init1: 138 opt: 477 Z-score: 475.0 bits: 98.3 E(32554): 3.9e-20
Smith-Waterman score: 477; 32.9% identity (62.4% similar) in 255 aa overlap (167-419:491-731)
140 150 160 170 180 190
pF1KB6 VGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQK-TLRPRFKIIGGEFTTIENQPWFAA
.:: . ... ...:: .. . :: ..
CCDS12 PESPVVSTPTKSMQALSTVPLDWVTVPKLQECGARPAMEKPTRVVGGFGAASGEVPWQVS
470 480 490 500 510 520
200 210 220 230 240 250
pF1KB6 IYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFE
. . :: . ::..... :..::.::: .. : :. ..:: . : . . .:.
CCDS12 L----KEGS-RHFCGATVVGDRWLLSAAHCF-NHTKVEQVRAHLGTASLLGLGGSPVKIG
530 540 550 560 570
260 270 280 290 300 310
pF1KB6 VENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEI
.. ..:: :. : :.:.:.. : . .. :: .::: . : .: :
CCDS12 LRRVVLHPLYNPGILDF--DLAVLELASPLAF----NKYIQPVCLPLAIQKFPVGRKCMI
580 590 600 610 620
320 330 340 350 360 370
pF1KB6 TGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGD
.:.:. . . :: :. . : .:... :. :. .: .:.::. . :.::::::
CCDS12 SGWGNTQEGNATKPELLQKASVGIIDQKTCSV--LYNFSLTDRMICAGFLEGKVDSCQGD
630 640 650 660 670 680
380 390 400 410 420 430
pF1KB6 SGGPLVCS-LQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
:::::.: : . :.:::::: ::: :::::::.... ::
CCDS12 SGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPMSPPS
690 700 710 720 730 740
CCDS12 TTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAP
750 760 770 780 790 800
>>CCDS45469.1 PRSS8 gene_id:5652|Hs108|chr16 (343 aa)
initn: 445 init1: 246 opt: 541 Z-score: 544.4 bits: 109.5 E(32554): 5.3e-24
Smith-Waterman score: 541; 36.8% identity (61.0% similar) in 269 aa overlap (168-425:37-287)
140 150 160 170 180 190
pF1KB6 GLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIY
:: . :. .: :: .. . :: ..:
CCDS45 LGPGQLGAVAILLYLGLLRSGTGAEGAEAPCG---VAPQARITGGSSAVAGQWPWQVSI-
10 20 30 40 50 60
200 210 220 230 240 250
pF1KB6 RRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVE
..: ..::::::.: ::.::.::: . .:: : : :: .:.: .. ..
CCDS45 -TYEG---VHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLK
70 80 90 100 110
260 270 280 290 300 310
pF1KB6 NLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITG
..: : .: . . ..:::::.. .: :: :. ::::. . : : .::
CCDS45 DIIPHPSYLQE--GSQGDIALLQL----SRPITFSRYIRPICLPAANASFPNGLHCTVTG
120 130 140 150 160 170
320 330 340 350 360
pF1KB6 FGK-ENSTDYLYPEQLKMTVVKLISHREC----------QQPHYYGSEVTTKMLCAADPQ
.:. :.. : :. :.. : :::.. : ..::. : :.::. .
CCDS45 WGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHF----VQEDMVCAGYVE
180 190 200 210 220
370 380 390 400 410 420
pF1KB6 WKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEE
:.::::::::: : ..: :::::::: .:. ...::::: .: . ::.:.. :
CCDS45 GGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTEL
230 240 250 260 270 280
430
pF1KB6 NGLAL
CCDS45 QPRVVPQTQESQPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH
290 300 310 320 330 340
431 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:33:42 2016 done: Sat Nov 5 11:33:42 2016
Total Scan time: 2.910 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]