FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6592, 406 aa
  1>>>pF1KB6592 406 - 406 aa - 406 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9166+/-0.000513; mu= 14.0855+/- 0.032
 mean_var=79.4739+/-16.579, 0's: 0 Z-trim(108.0): 77  B-trim: 381 in 1/50
 Lambda= 0.143867
 statistics sampled from 15976 (16022) to 15976 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.535), E-opt: 0.2 (0.188), width:  16
 Scan time:  8.400

The best scores are:                                      opt bits E(85289)
NP_057213 (OMIM: 616008) COP9 signalosome complex  ( 406) 2594 548.7 9.5e-156
NP_001317656 (OMIM: 616008) COP9 signalosome compl ( 420) 2305 488.7 1.1e-137
NP_001244935 (OMIM: 616008) COP9 signalosome compl ( 352) 2139 454.2 2.3e-127


>>NP_057213 (OMIM: 616008) COP9 signalosome complex subu  (406 aa)
 initn: 2594 init1: 2594 opt: 2594  Z-score: 2917.1  bits: 548.7 E(85289): 9.5e-156
Smith-Waterman score: 2594; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406)

               10        20        30        40        50        60
pF1KB6 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
              310       320       330       340       350       360

              370       380       390       400      
pF1KB6 FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ
              370       380       390       400      

>>NP_001317656 (OMIM: 616008) COP9 signalosome complex s  (420 aa)
 initn: 2305 init1: 2305 opt: 2305  Z-score: 2592.7  bits: 488.7 E(85289): 1.1e-137
Smith-Waterman score: 2305; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363)

               10        20        30        40        50        60
pF1KB6 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
              310       320       330       340       350       360

              370       380       390       400                    
pF1KB6 FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ              
       :::                                                         
NP_001 FETSGNHQSIFCLWIYLVWIVHINGIIQYVTCDLLADSTQHSIFRVHPCHGSTRSPANVG
              370       380       390       400       410       420

>>NP_001244935 (OMIM: 616008) COP9 signalosome complex s  (352 aa)
 initn: 2128 init1: 2128 opt: 2139  Z-score: 2407.7  bits: 454.2 E(85289): 2.3e-127
Smith-Waterman score: 2139; 96.0% identity (97.7% similar) in 354 aa overlap (1-354:1-352)

               10        20        30        40        50        60
pF1KB6 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
       :::::::::::::::::::::::::::::::::: ::  .. :.  : : :...      
NP_001 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKHEKPCQRGIS--RSNHFVSK      
              310       320       330       340         350        

              370       380       390       400      
pF1KB6 FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ




406 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 20:41:50 2016 done: Sat Nov  5 20:41:51 2016
 Total Scan time:  8.400 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]