Result of FASTA (omim) for
pF1KB6588
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6588, 406 aa
1>>>pF1KB6588 406 - 406 aa - 406 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6052+/-0.000391; mu= 10.7122+/- 0.024
mean_var=101.2428+/-20.518, 0's: 0 Z-trim(114.3): 183 B-trim: 336 in 2/53
Lambda= 0.127465
statistics sampled from 23814 (24005) to 23814 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.281), width: 16
Scan time: 8.550
The best scores are: opt bits E(85289)
NP_002796 (OMIM: 601681) 26S protease regulatory s ( 406) 2613 491.2 1.9e-138
NP_001186092 (OMIM: 601681) 26S protease regulator ( 398) 2557 480.9 2.3e-135
NP_002794 (OMIM: 154365) 26S protease regulatory s ( 433) 1168 225.5 1.9e-58
NP_002793 (OMIM: 602706) 26S protease regulatory s ( 440) 1161 224.2 4.8e-58
XP_016876959 (OMIM: 602706) PREDICTED: 26S proteas ( 367) 1156 223.3 7.7e-58
NP_001317141 (OMIM: 602706) 26S protease regulator ( 367) 1156 223.3 7.7e-58
NP_002797 (OMIM: 602708) 26S protease regulatory s ( 403) 1141 220.5 5.7e-57
NP_002795 (OMIM: 186852) 26S protease regulatory s ( 439) 1055 204.8 3.5e-52
NP_006494 (OMIM: 602707) 26S protease regulatory s ( 418) 1052 204.2 4.9e-52
NP_694546 (OMIM: 602707) 26S protease regulatory s ( 387) 1051 204.0 5.3e-52
XP_016876961 (OMIM: 602708) PREDICTED: 26S proteas ( 288) 1008 196.0 9.8e-50
XP_016873515 (OMIM: 186852) PREDICTED: 26S proteas ( 461) 995 193.7 7.7e-49
XP_011523903 (OMIM: 604581,610246,614487) PREDICTE ( 730) 713 142.0 4.6e-33
NP_006787 (OMIM: 604581,610246,614487) AFG3-like p ( 797) 713 142.0 5e-33
NP_009057 (OMIM: 167320,601023,613954,616687) tran ( 806) 689 137.6 1.1e-31
NP_003110 (OMIM: 602783,607259) paraplegin isoform ( 795) 634 127.5 1.2e-28
XP_006721327 (OMIM: 602783,607259) PREDICTED: para ( 809) 634 127.5 1.2e-28
NP_001304728 (OMIM: 613940,616577) spermatogenesis ( 695) 631 126.9 1.5e-28
XP_011529981 (OMIM: 613940,616577) PREDICTED: sper ( 790) 631 126.9 1.7e-28
XP_016863317 (OMIM: 613940,616577) PREDICTED: sper ( 819) 631 126.9 1.8e-28
NP_001332785 (OMIM: 613940,616577) spermatogenesis ( 892) 631 126.9 1.9e-28
NP_660208 (OMIM: 613940,616577) spermatogenesis-as ( 893) 631 126.9 1.9e-28
XP_016879087 (OMIM: 602783,607259) PREDICTED: para ( 561) 626 125.9 2.4e-28
XP_016879086 (OMIM: 602783,607259) PREDICTED: para ( 618) 626 125.9 2.6e-28
NP_001303242 (OMIM: 601498,614862,614863,616617) p ( 892) 627 126.2 3.1e-28
XP_011512963 (OMIM: 601498,614862,614863,616617) P ( 952) 627 126.2 3.3e-28
NP_000278 (OMIM: 601498,614862,614863,616617) pero ( 980) 627 126.2 3.4e-28
NP_001240795 (OMIM: 607472) ATP-dependent zinc met ( 683) 619 124.7 7e-28
NP_055078 (OMIM: 607472) ATP-dependent zinc metall ( 716) 619 124.7 7.2e-28
XP_011517602 (OMIM: 607472) PREDICTED: ATP-depende ( 740) 619 124.7 7.4e-28
NP_647473 (OMIM: 607472) ATP-dependent zinc metall ( 773) 619 124.7 7.7e-28
XP_016863319 (OMIM: 613940,616577) PREDICTED: sper ( 593) 607 122.4 2.9e-27
XP_011515297 (OMIM: 611941) PREDICTED: ATPase fami ( 953) 610 123.1 2.9e-27
XP_011515296 (OMIM: 611941) PREDICTED: ATPase fami (1260) 610 123.2 3.7e-27
NP_054828 (OMIM: 611941) ATPase family AAA domain- (1390) 610 123.2 4e-27
XP_016863318 (OMIM: 613940,616577) PREDICTED: sper ( 765) 603 121.8 5.9e-27
XP_016863316 (OMIM: 613940,616577) PREDICTED: sper ( 823) 603 121.8 6.3e-27
XP_016863315 (OMIM: 613940,616577) PREDICTED: sper ( 859) 603 121.8 6.5e-27
XP_011529980 (OMIM: 613940,616577) PREDICTED: sper ( 916) 603 121.8 6.9e-27
XP_016863314 (OMIM: 613940,616577) PREDICTED: sper ( 917) 603 121.8 6.9e-27
XP_016867808 (OMIM: 214100,234580,601539,602136) P ( 700) 597 120.6 1.2e-26
NP_001269607 (OMIM: 214100,234580,601539,602136) p (1075) 597 120.7 1.7e-26
NP_001269606 (OMIM: 214100,234580,601539,602136) p (1226) 597 120.8 1.9e-26
NP_000457 (OMIM: 214100,234580,601539,602136) pero (1283) 597 120.8 2e-26
XP_011531234 (OMIM: 615347) PREDICTED: ATPase fami ( 791) 581 117.7 1e-25
XP_011531233 (OMIM: 615347) PREDICTED: ATPase fami ( 837) 581 117.7 1e-25
XP_011531232 (OMIM: 615347) PREDICTED: ATPase fami ( 841) 581 117.7 1.1e-25
XP_011531231 (OMIM: 615347) PREDICTED: ATPase fami ( 843) 581 117.7 1.1e-25
XP_011531230 (OMIM: 615347) PREDICTED: ATPase fami ( 849) 581 117.7 1.1e-25
XP_006712094 (OMIM: 615347) PREDICTED: ATPase fami (1067) 581 117.8 1.3e-25
>>NP_002796 (OMIM: 601681) 26S protease regulatory subun (406 aa)
initn: 2613 init1: 2613 opt: 2613 Z-score: 2606.7 bits: 491.2 E(85289): 1.9e-138
Smith-Waterman score: 2613; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406)
10 20 30 40 50 60
pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK
310 320 330 340 350 360
370 380 390 400
pF1KB6 GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
370 380 390 400
>>NP_001186092 (OMIM: 601681) 26S protease regulatory su (398 aa)
initn: 2557 init1: 2557 opt: 2557 Z-score: 2551.2 bits: 480.9 E(85289): 2.3e-135
Smith-Waterman score: 2557; 100.0% identity (100.0% similar) in 398 aa overlap (9-406:1-398)
10 20 30 40 50 60
pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB6 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK
300 310 320 330 340 350
370 380 390 400
pF1KB6 GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
360 370 380 390
>>NP_002794 (OMIM: 154365) 26S protease regulatory subun (433 aa)
initn: 1149 init1: 1149 opt: 1168 Z-score: 1170.2 bits: 225.5 E(85289): 1.9e-58
Smith-Waterman score: 1168; 50.8% identity (73.9% similar) in 372 aa overlap (22-392:53-418)
10 20 30 40 50
pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNE
: :.::.:: : : .. .
NP_002 RALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGI---KESDTGLAPPALWD
30 40 50 60 70
60 70 80 90 100 110
pF1KB6 LNAKVRLLREELQLLQEQGSYVGEVVRA-MDKKKVLVKVHPEGKFVVDVDKNIDINDVTP
: : . :. : : : . ... : . : ...:. .:::::.. .. .:.
NP_002 LAADKQTLQSEQPL---QVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEE
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB6 NCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVK
. ::.. ..: .: :: :.:: :..:.::. :: :: .:: .::....::.: :.
NP_002 GMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLL
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB6 HPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARM
::: : ::: ::::::.::::::::: :::::..:: :::: :::::::..::::::
NP_002 HPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARM
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB6 VRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIK
::::: ::: . .::.::::.::..:.. :.:::.:::::::::.::::::. :::
NP_002 VRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIK
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB6 VIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAEL
:.::::: : :: ::.::::.:::::: :. :.: :.:::.:.:.. : : .. .:.:
NP_002 VLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARL
320 330 340 350 360 370
360 370 380 390 400
pF1KB6 MPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
:...:::...:::::::.:.: :: .:..:: :: ::..
NP_002 CPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN
380 390 400 410 420 430
>>NP_002793 (OMIM: 602706) 26S protease regulatory subun (440 aa)
initn: 1096 init1: 1073 opt: 1161 Z-score: 1163.1 bits: 224.2 E(85289): 4.8e-58
Smith-Waterman score: 1161; 46.3% identity (74.8% similar) in 393 aa overlap (4-396:44-432)
10 20 30
pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQL
:. .. : .. :. : .:.. :
NP_002 GKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLL
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB6 IVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEG
. ... : : : . :. : . : ... :. :: . . .: ....:.. .
NP_002 M----EEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGS
80 90 100 110 120
100 110 120 130 140 150
pF1KB6 KFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGG
. :.. . .: . . :.: : : . ... .: . .::::..: :::.:. :: :::
NP_002 EHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 LDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIR
::.::.:::: .:::. ::: .: .:: ::::.:::::::::::::.:::..:. ::.:
NP_002 LDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLR
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 VSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTM
: ::::.::..:.: ..::::: .:.::::::.:.::::.::..: ...:::. :.::::
NP_002 VVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTM
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 LELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHS
::::::::::.. ..:::::::::. :: ::.:::::::::::: :.:... :..::.
NP_002 LELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHT
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB6 RKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQK
.:.:. ..: . :::..:..:::::..::::::..::.:::. . .:. :
NP_002 SRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYK
370 380 390 400 410 420
400
pF1KB6 DSEKNMSIKKLWK
.:
NP_002 KQEGTPEGLYL
430 440
>>XP_016876959 (OMIM: 602706) PREDICTED: 26S protease re (367 aa)
initn: 1096 init1: 1073 opt: 1156 Z-score: 1159.4 bits: 223.3 E(85289): 7.7e-58
Smith-Waterman score: 1156; 49.9% identity (77.9% similar) in 353 aa overlap (44-396:7-359)
20 30 40 50 60 70
pF1KB6 GKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYV
: : : . :. : . : ... :. :
XP_016 MEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSV
10 20 30
80 90 100 110 120 130
pF1KB6 GEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDP
: . . .: ....:.. .. :.. . .: . . :.: : : . ... .: . .::
XP_016 GTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDP
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 LVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPG
::..: :::.:. :: :::::.::.:::: .:::. ::: .: .:: ::::.::::::
XP_016 LVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPG
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB6 TGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDS
:::::::.:::..:. ::.:: ::::.::..:.: ..::::: .:.::::::.:.::::.
XP_016 TGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB6 IGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDR
::..: ...:::. :.::::::::::::::.. ..:::::::::. :: ::.:::::::
XP_016 IGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB6 KIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRE
::::: :.:... :..::. .:.:. ..: . :::..:..:::::..::::
XP_016 KIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRE
280 290 300 310 320 330
380 390 400
pF1KB6 RRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
::..::.:::. . .:. : .:
XP_016 RRMKVTNEDFKKSKENVLYKKQEGTPEGLYL
340 350 360
>>NP_001317141 (OMIM: 602706) 26S protease regulatory su (367 aa)
initn: 1096 init1: 1073 opt: 1156 Z-score: 1159.4 bits: 223.3 E(85289): 7.7e-58
Smith-Waterman score: 1156; 49.9% identity (77.9% similar) in 353 aa overlap (44-396:7-359)
20 30 40 50 60 70
pF1KB6 GKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYV
: : : . :. : . : ... :. :
NP_001 MEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSV
10 20 30
80 90 100 110 120 130
pF1KB6 GEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDP
: . . .: ....:.. .. :.. . .: . . :.: : : . ... .: . .::
NP_001 GTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDP
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 LVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPG
::..: :::.:. :: :::::.::.:::: .:::. ::: .: .:: ::::.::::::
NP_001 LVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPG
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB6 TGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDS
:::::::.:::..:. ::.:: ::::.::..:.: ..::::: .:.::::::.:.::::.
NP_001 TGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB6 IGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDR
::..: ...:::. :.::::::::::::::.. ..:::::::::. :: ::.:::::::
NP_001 IGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB6 KIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRE
::::: :.:... :..::. .:.:. ..: . :::..:..:::::..::::
NP_001 KIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRE
280 290 300 310 320 330
380 390 400
pF1KB6 RRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
::..::.:::. . .:. : .:
NP_001 RRMKVTNEDFKKSKENVLYKKQEGTPEGLYL
340 350 360
>>NP_002797 (OMIM: 602708) 26S protease regulatory subun (403 aa)
initn: 1136 init1: 1136 opt: 1141 Z-score: 1143.8 bits: 220.5 E(85289): 5.7e-57
Smith-Waterman score: 1141; 50.3% identity (76.1% similar) in 356 aa overlap (42-397:40-393)
20 30 40 50 60 70
pF1KB6 EEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGS
:..:. : .::. . . ...:. :: :.
NP_002 RRLLIMADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQ
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB6 YVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKV
::::.. . ..: .::. ..:: ...: . . :. :::: . :. . :: .:
NP_002 IVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREV
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB6 DPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGP
:::: : : . .: ::::..::.:..::::::. .::::. .:: ::: :::::
NP_002 DPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGP
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB6 PGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEI
::::::::::::: . ::.:..: .: .:.:.:::.::..::.: .::.: : :::::::
NP_002 PGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEI
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB6 DSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRI
:.::. :. :...: :.:::..:::::.:::.. . .:.:::::: : :: :::::::.
NP_002 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRL
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB6 DRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL
::::.. :::.:::::::::. .. :. . :..: : .::....:::::::.:.
NP_002 DRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAI
310 320 330 340 350 360
380 390 400
pF1KB6 RERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
: . :.:::: :: :: ::.:
NP_002 RADHDFVVQEDFMKAVRKVA--DSKKLESKLDYKPV
370 380 390 400
>>NP_002795 (OMIM: 186852) 26S protease regulatory subun (439 aa)
initn: 1041 init1: 1019 opt: 1055 Z-score: 1057.8 bits: 204.8 E(85289): 3.5e-52
Smith-Waterman score: 1055; 45.1% identity (73.7% similar) in 377 aa overlap (20-393:55-430)
10 20 30 40
pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQR
... : .::: . . ..: .......
NP_002 EQDGIGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNK
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB6 NE---LNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDIN
. .. ..:: . . .:.:. . .. : ...:. . . . : .: .
NP_002 TLPYLVSNVIELLDVDPNDQEEDGANI-DLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAE
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB6 DVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIE
. :. :.. .::: . . ::.. : :. : :.. : : ::::::::.:. :.:
NP_002 KLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIV
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB6 LPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGE
::..: : :: ::: :::::.:::::::::::::: : .: ::....: .::: :::.
NP_002 LPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGD
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB6 GARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEAT
::..::. :..:.:.::::::.::.:.::..:... ..:: ::::::::::::::::. .
NP_002 GAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPN
270 280 290 300 310 320
290 300 310 320 330 340
pF1KB6 KNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRK
..::: ::::.:::: :::: ::.::::::: :::::: :..:::::::.. .: ..
NP_002 TQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEE
330 340 350 360 370 380
350 360 370 380 390 400
pF1KB6 IAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
.:. .::. :.::.:::: :::. ...:.::. .. .:. :
NP_002 LARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA
390 400 410 420 430
>>NP_006494 (OMIM: 602707) 26S protease regulatory subun (418 aa)
initn: 1045 init1: 1003 opt: 1052 Z-score: 1055.1 bits: 204.2 E(85289): 4.9e-52
Smith-Waterman score: 1073; 42.5% identity (71.4% similar) in 398 aa overlap (1-398:27-414)
10 20 30
pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLI
... ::: .::. . : : .: .
NP_006 MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEY
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 VNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGK
..:...::.. . :.:. ::.. .: .:. ..:.:.. ..: ..
NP_006 IKDEQKNLKK-----EFLHAQ-----EEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSN
70 80 90 100 110
100 110 120 130 140 150
pF1KB6 FVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGL
. : . ..:: . . :: :::.. : .: .:: ..: . .. .. :: : :::.
NP_006 YYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGM
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 DKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRV
: : .:..:..:::. : ::.. .:: :.:::.::::: :::.::.:::::: .::::
NP_006 DIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 SGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTML
:::.:::..::: ::::..: .:.:.::.:::.::::.:...:... .:.: :::: .:
NP_006 VGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 ELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSR
:::::.:::. . :.:::::::: : :: :::::::.::::::: :... . :.. .
NP_006 ELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITS
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 KMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKD
::::.. ..:. . :::.....: :.:: :.:: : : .::: : :..::
NP_006 KMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKD
360 370 380 390 400 410
400
pF1KB6 SEKNMSIKKLWK
...
NP_006 EQEHEFYK
>>NP_694546 (OMIM: 602707) 26S protease regulatory subun (387 aa)
initn: 1026 init1: 1003 opt: 1051 Z-score: 1054.7 bits: 204.0 E(85289): 5.3e-52
Smith-Waterman score: 1051; 44.0% identity (72.7% similar) in 366 aa overlap (33-398:18-383)
10 20 30 40 50 60
pF1KB6 LDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREE
: :. . .: : . ..:. .::
NP_694 MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKEE
10 20 30 40
70 80 90 100 110 120
pF1KB6 LQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYT
.. .: .:. ..:.:.. ..: ... : . ..:: . . :: :::.. : .
NP_694 VKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 LHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQ
: .:: ..: . .. .. :: : :::.: : .:..:..:::. : ::.. .::
NP_694 LVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 PKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHA
:.:::.::::: :::.::.:::::: .:::: :::.:::..::: ::::..: .:.:.:
NP_694 PRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 PSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILD
:.:::.::::.:...:... .:.: :::: .::::::.:::. . :.:::::::: : ::
NP_694 PAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLD
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 SALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGV
:::::::.::::::: :... . :.. . ::::.. ..:. . :::.....
NP_694 PALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSI
290 300 310 320 330 340
370 380 390 400
pF1KB6 CTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
: :.:: :.:: : : .::: : :..:: ...
NP_694 CQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK
350 360 370 380
406 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:23:41 2016 done: Fri Nov 4 23:23:42 2016
Total Scan time: 8.550 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]