Result of FASTA (omim) for
pF1KB6569
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6569, 375 aa
1>>>pF1KB6569 375 - 375 aa - 375 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4167+/-0.000483; mu= 4.9197+/- 0.031
mean_var=507.3270+/-104.474, 0's: 0 Z-trim(122.7): 430 B-trim: 719 in 1/60
Lambda= 0.056942
statistics sampled from 40830 (41289) to 40830 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.484), width: 16
Scan time: 10.400
The best scores are: opt bits E(85289)
NP_003010 (OMIM: 178635) pulmonary surfactant-asso ( 375) 2603 227.8 3.1e-59
XP_011538389 (OMIM: 178635) PREDICTED: pulmonary s ( 375) 2603 227.8 3.1e-59
XP_011538390 (OMIM: 178635) PREDICTED: pulmonary s ( 336) 1772 159.5 1e-38
XP_005257115 (OMIM: 114000,120150,130000,130060,16 (1374) 660 69.1 7e-11
XP_011522643 (OMIM: 114000,120150,130000,130060,16 (1398) 660 69.1 7.1e-11
NP_000079 (OMIM: 114000,120150,130000,130060,16620 (1464) 660 69.1 7.3e-11
XP_011532990 (OMIM: 610043) PREDICTED: collagen al ( 557) 630 66.0 2.4e-10
NP_000081 (OMIM: 120180,130020,130050) collagen al (1466) 638 67.3 2.6e-10
XP_011532994 (OMIM: 610043) PREDICTED: collagen al ( 472) 625 65.5 2.9e-10
NP_775736 (OMIM: 610043) collagen alpha-1(XXIII) c ( 540) 625 65.6 3.1e-10
XP_006714996 (OMIM: 610043) PREDICTED: collagen al ( 566) 625 65.6 3.2e-10
XP_011526344 (OMIM: 120216) PREDICTED: collagen al (1744) 633 67.0 3.7e-10
NP_056534 (OMIM: 120216) collagen alpha-3(V) chain (1745) 633 67.0 3.7e-10
XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 630 66.8 4.4e-10
NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838) 630 66.8 4.5e-10
NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838) 630 66.8 4.5e-10
XP_006714997 (OMIM: 610043) PREDICTED: collagen al ( 557) 608 64.2 8.4e-10
XP_016865740 (OMIM: 120290,184840,215150,277610,60 (1342) 615 65.4 9e-10
XP_011512604 (OMIM: 120290,184840,215150,277610,60 (1365) 615 65.4 9.1e-10
XP_011512602 (OMIM: 120290,184840,215150,277610,60 (1438) 615 65.4 9.4e-10
XP_011512601 (OMIM: 120290,184840,215150,277610,60 (1498) 615 65.4 9.6e-10
NP_542410 (OMIM: 120290,184840,215150,277610,60186 (1629) 615 65.5 1e-09
NP_542412 (OMIM: 120290,184840,215150,277610,60186 (1650) 615 65.5 1e-09
XP_016865739 (OMIM: 120290,184840,215150,277610,60 (1736) 615 65.5 1e-09
NP_542411 (OMIM: 120290,184840,215150,277610,60186 (1736) 615 65.5 1e-09
XP_016883155 (OMIM: 120270,600969,603932) PREDICTE ( 486) 602 63.6 1.1e-09
XP_011526847 (OMIM: 120270,600969,603932) PREDICTE ( 552) 602 63.7 1.2e-09
NP_001844 (OMIM: 120270,600969,603932) collagen al ( 684) 602 63.8 1.3e-09
XP_006714999 (OMIM: 610043) PREDICTED: collagen al ( 545) 594 63.0 1.8e-09
XP_011515191 (OMIM: 610026) PREDICTED: collagen al (1058) 600 64.0 1.9e-09
NP_542992 (OMIM: 120350,616720) collagen alpha-1(X ( 668) 595 63.3 1.9e-09
NP_065084 (OMIM: 120251) collagen alpha-1(VIII) ch ( 744) 596 63.4 1.9e-09
NP_001841 (OMIM: 120251) collagen alpha-1(VIII) ch ( 744) 596 63.4 1.9e-09
XP_011532991 (OMIM: 610043) PREDICTED: collagen al ( 548) 593 63.0 2e-09
NP_001307880 (OMIM: 120350,616720) collagen alpha- ( 680) 595 63.3 2e-09
XP_011537597 (OMIM: 120350,616720) PREDICTED: coll ( 701) 595 63.3 2e-09
XP_011515189 (OMIM: 610026) PREDICTED: collagen al (1264) 600 64.1 2.1e-09
XP_016868641 (OMIM: 610026) PREDICTED: collagen al (1264) 600 64.1 2.1e-09
XP_016868640 (OMIM: 610026) PREDICTED: collagen al (1552) 600 64.2 2.3e-09
XP_016868639 (OMIM: 610026) PREDICTED: collagen al (1564) 600 64.2 2.3e-09
XP_011515188 (OMIM: 610026) PREDICTED: collagen al (1577) 600 64.2 2.3e-09
XP_011515187 (OMIM: 610026) PREDICTED: collagen al (1588) 600 64.2 2.3e-09
XP_011515186 (OMIM: 610026) PREDICTED: collagen al (1593) 600 64.2 2.3e-09
XP_011515185 (OMIM: 610026) PREDICTED: collagen al (1606) 600 64.3 2.3e-09
XP_011508875 (OMIM: 120190,130000) PREDICTED: coll (1453) 599 64.1 2.3e-09
NP_690848 (OMIM: 610026) collagen alpha-1(XXII) ch (1626) 600 64.3 2.3e-09
XP_016874320 (OMIM: 108300,120140,132450,150600,15 (1305) 595 63.7 2.8e-09
NP_149162 (OMIM: 108300,120140,132450,150600,15121 (1418) 595 63.8 2.9e-09
XP_016871174 (OMIM: 120350,616720) PREDICTED: coll ( 678) 588 62.7 2.9e-09
XP_016874319 (OMIM: 108300,120140,132450,150600,15 (1465) 595 63.8 3e-09
>>NP_003010 (OMIM: 178635) pulmonary surfactant-associat (375 aa)
initn: 2603 init1: 2603 opt: 2603 Z-score: 1184.4 bits: 227.8 E(85289): 3.1e-59
Smith-Waterman score: 2603; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KB6 MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGRE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 GAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 QQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKW
310 320 330 340 350 360
370
pF1KB6 NDRACGEKRLVVCEF
:::::::::::::::
NP_003 NDRACGEKRLVVCEF
370
>>XP_011538389 (OMIM: 178635) PREDICTED: pulmonary surfa (375 aa)
initn: 2603 init1: 2603 opt: 2603 Z-score: 1184.4 bits: 227.8 E(85289): 3.1e-59
Smith-Waterman score: 2603; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KB6 MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGRE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 GAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 QQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKW
310 320 330 340 350 360
370
pF1KB6 NDRACGEKRLVVCEF
:::::::::::::::
XP_011 NDRACGEKRLVVCEF
370
>>XP_011538390 (OMIM: 178635) PREDICTED: pulmonary surfa (336 aa)
initn: 1758 init1: 1758 opt: 1772 Z-score: 815.9 bits: 159.5 E(85289): 1e-38
Smith-Waterman score: 2212; 89.6% identity (89.6% similar) in 375 aa overlap (1-375:1-336)
10 20 30 40 50 60
pF1KB6 MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGRE
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSG--------------
70 80 90 100
130 140 150 160 170 180
pF1KB6 GPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNT
:::::::::::::::::::::::::::::::::::
XP_011 -------------------------EVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNT
110 120 130 140
190 200 210 220 230 240
pF1KB6 GAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQH
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB6 LQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAAL
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB6 QQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKW
270 280 290 300 310 320
370
pF1KB6 NDRACGEKRLVVCEF
:::::::::::::::
XP_011 NDRACGEKRLVVCEF
330
>>XP_005257115 (OMIM: 114000,120150,130000,130060,166200 (1374 aa)
initn: 1636 init1: 618 opt: 660 Z-score: 316.3 bits: 69.1 E(85289): 7e-11
Smith-Waterman score: 660; 51.3% identity (60.3% similar) in 199 aa overlap (44-236:531-728)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAG
:.:::: : : : : : : :: ::
XP_005 VAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAG
510 520 530 540 550 560
80 90 100 110 120 130
pF1KB6 QAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQG
: : :: :: : .:. : .: ::::: .: : : ::::: : :: ::.:. : ::
XP_005 QDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG
570 580 590 600 610 620
140 150 160 170 180 190
pF1KB6 KPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQG
::: : :: .:: : : : : : ::: :: : :::.::::. :: : .:: : .:
XP_005 PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG
630 640 650 660 670 680
200 210 220 230 240
pF1KB6 SPGARG---PPGLKGDKGI---PGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQ
:: :: ::: : .: ::. ::::..: : : : . .:::
XP_005 FPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPG-APGSQGAPGLQGMPGERGAAGLP
690 700 710 720 730
250 260 270 280 290 300
pF1KB6 YKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAK
XP_005 GPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP
740 750 760 770 780 790
>--
initn: 2080 init1: 597 opt: 603 Z-score: 291.0 bits: 64.4 E(85289): 1.8e-09
Smith-Waterman score: 604; 48.6% identity (59.9% similar) in 177 aa overlap (46-222:755-928)
20 30 40 50 60 70
pF1KB6 LGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQA
: ::.:: : :: : : : :: :..
XP_005 GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGES
730 740 750 760 770 780
80 90 100 110 120 130
pF1KB6 GMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKP
: : :::.: .: :. ::::: : .: .:::: : :: :. : : .:. :: :
XP_005 GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA
790 800 810 820 830 840
140 150 160 170 180 190
pF1KB6 GPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSP
:: : :: :.::::: .: ::: ::: : : :: : : : .: : .::.:.
XP_005 GPAGPPGPIGNVGAPGAKG---ARGSAGPPGATGFPGAAGRVGPPGPSGEPGKQGPSGAS
850 860 870 880 890 900
200 210 220 230 240 250
pF1KB6 GARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFP
: ::::: : :. : : .:. : :
XP_005 GERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAP
910 920 930 940 950 960
>--
initn: 1116 init1: 570 opt: 593 Z-score: 286.5 bits: 63.6 E(85289): 3.2e-09
Smith-Waterman score: 594; 50.3% identity (61.4% similar) in 189 aa overlap (44-220:234-413)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPG---LPG
:.: ::: :. : ::.: .: :: :::
XP_005 PPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPG
210 220 230 240 250 260
80 90 100 110 120
pF1KB6 AAGQAGMPG------QAGPVGPKGDNGSVGEPGPKGDTGPSGPPGP---PGVPGPAGREG
:. :. : .:::.::::. :: :: : :. :: : :: ::.::::: .:
XP_005 MKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARG
270 280 290 300 310 320
130 140 150 160 170 180
pF1KB6 PLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTG
: : :: ::: : ::: ::. :..::.: :::.: :: : .:: :. :
XP_005 NDGATGAAGP---PGPTGPAGP------PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPG
330 340 350 360 370
190 200 210 220 230 240
pF1KB6 AAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHL
: ::: :: :.::: : :: :: .: :: :: : :
XP_005 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSG
380 390 400 410 420 430
250 260 270 280 290 300
pF1KB6 QAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQ
XP_005 EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRG
440 450 460 470 480 490
>--
initn: 2437 init1: 545 opt: 567 Z-score: 275.0 bits: 61.4 E(85289): 1.4e-08
Smith-Waterman score: 567; 48.6% identity (58.2% similar) in 177 aa overlap (46-222:932-1102)
20 30 40 50 60 70
pF1KB6 LGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQA
: ::::: : .: ::: : : ::: :
XP_005 GERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAP
910 920 930 940 950 960
80 90 100 110 120 130
pF1KB6 GMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKP
: :: .::.: .:: : .: :: : .:: : :: : :: : .: :.::. : .:.
XP_005 GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR
970 980 990 1000 1010 1020
140 150 160 170 180 190
pF1KB6 GPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSP
: .: :: : :.:: :: .:: : ::: :: :: :.::. : : : .:: :
XP_005 GFSGLQGPPGPPGSPGEQGPSGASGPAGP---RGPPGSAGAPGKDGLNGLPGPIGP---P
1030 1040 1050 1060 1070
200 210 220 230 240 250
pF1KB6 GARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFP
: :: : : : :: : : : :
XP_005 GPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVR
1080 1090 1100 1110 1120 1130
>--
initn: 405 init1: 405 opt: 418 Z-score: 208.8 bits: 49.2 E(85289): 6.8e-05
Smith-Waterman score: 440; 51.5% identity (62.1% similar) in 132 aa overlap (71-202:414-530)
50 60 70 80 90 100
pF1KB6 SSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKG
: : .: : .:: ::::..: : :: ::
XP_005 PAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKG
390 400 410 420 430 440
110 120 130 140 150 160
pF1KB6 DTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARG
::: .: ::: :: :: :: :..:. : .:.::: : :: :: :.:: .: :: :
XP_005 DTGAKGEPGPVGVQGP---PGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG
450 460 470 480 490 500
170 180 190 200 210 220
pF1KB6 LAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESG
.::::: :::: : : ::.:::: : ::
XP_005 VAGPKGP---AGERGSP---------GPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG
510 520 530 540
230 240 250 260 270 280
pF1KB6 LPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLL
XP_005 PDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVG
550 560 570 580 590 600
>>XP_011522643 (OMIM: 114000,120150,130000,130060,166200 (1398 aa)
initn: 2179 init1: 618 opt: 660 Z-score: 316.2 bits: 69.1 E(85289): 7.1e-11
Smith-Waterman score: 660; 51.3% identity (60.3% similar) in 199 aa overlap (44-236:465-662)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAG
:.:::: : : : : : : :: ::
XP_011 VAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAG
440 450 460 470 480 490
80 90 100 110 120 130
pF1KB6 QAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQG
: : :: :: : .:. : .: ::::: .: : : ::::: : :: ::.:. : ::
XP_011 QDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG
500 510 520 530 540 550
140 150 160 170 180 190
pF1KB6 KPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQG
::: : :: .:: : : : : : ::: :: : :::.::::. :: : .:: : .:
XP_011 PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG
560 570 580 590 600 610
200 210 220 230 240
pF1KB6 SPGARG---PPGLKGDKGI---PGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQ
:: :: ::: : .: ::. ::::..: : : : . .:::
XP_011 FPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPG-APGSQGAPGLQGMPGERGAAGLP
620 630 640 650 660 670
250 260 270 280 290 300
pF1KB6 YKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAK
XP_011 GPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP
680 690 700 710 720 730
>--
initn: 2131 init1: 579 opt: 585 Z-score: 282.9 bits: 62.9 E(85289): 5.1e-09
Smith-Waterman score: 607; 50.0% identity (60.9% similar) in 184 aa overlap (46-220:743-926)
20 30 40 50 60 70
pF1KB6 LGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQA
: : : : .: : ::.:: :: :.:
XP_011 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDA
720 730 740 750 760 770
80 90 100 110 120 130
pF1KB6 GMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKP
: :: :::.:: : :.:: :: :: : .:::: : :: ::: :: : .:: :: : :
XP_011 GPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP
780 790 800 810 820 830
140 150 160 170 180
pF1KB6 GPKGEAG---PKGEVGAPGMQGSAGARGLAGPKGERGVPGERG------VPGNTGAAGSA
:: :. : :.::.: : : .: : :: ::.: :: : .:: : ::.
XP_011 GPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQR
840 850 860 870 880 890
190 200 210 220 230 240
pF1KB6 GAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFS
:..: :. : :: ::: : .: :: .: .: ::
XP_011 GVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAP
900 910 920 930 940 950
250 260 270 280 290 300
pF1KB6 QYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVA
XP_011 GAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPV
960 970 980 990 1000 1010
>--
initn: 2112 init1: 567 opt: 582 Z-score: 281.6 bits: 62.7 E(85289): 6e-09
Smith-Waterman score: 593; 50.3% identity (60.5% similar) in 177 aa overlap (44-211:288-464)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAG
: : ::..: :. :::: :. : ::: :
XP_011 TAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPG
260 270 280 290 300 310
80 90 100 110 120
pF1KB6 QAGMPGQAGPVGPKGDNGS---VGEPGPKGDTGPSGPPGPPGVPGP---AGREGPLGKQG
:: :: : : :: ::. .: :: : ::::: :: : ::: .:. : :..:
XP_011 PAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKG
320 330 340 350 360 370
130 140 150 160 170 180
pF1KB6 NIGPQGKPGP---KGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAG
. : .:.::: .: :: :: : : .: : :: :: :::: :: :: :: :.::
XP_011 DTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAG
380 390 400 410 420 430
190 200 210 220 230 240
pF1KB6 SAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAA
: : .:::: :: : :. : ::
XP_011 PKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDG
440 450 460 470 480 490
>--
initn: 3511 init1: 545 opt: 567 Z-score: 274.9 bits: 61.5 E(85289): 1.4e-08
Smith-Waterman score: 567; 48.6% identity (58.2% similar) in 177 aa overlap (46-222:956-1126)
20 30 40 50 60 70
pF1KB6 LGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQA
: ::::: : .: ::: : : ::: :
XP_011 GERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAP
930 940 950 960 970 980
80 90 100 110 120 130
pF1KB6 GMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKP
: :: .::.: .:: : .: :: : .:: : :: : :: : .: :.::. : .:.
XP_011 GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR
990 1000 1010 1020 1030 1040
140 150 160 170 180 190
pF1KB6 GPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSP
: .: :: : :.:: :: .:: : ::: :: :: :.::. : : : .:: :
XP_011 GFSGLQGPPGPPGSPGEQGPSGASGPAGP---RGPPGSAGAPGKDGLNGLPGPIGP---P
1050 1060 1070 1080 1090
200 210 220 230 240 250
pF1KB6 GARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFP
: :: : : : :: : : : :
XP_011 GPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVR
1100 1110 1120 1130 1140 1150
>--
initn: 731 init1: 386 opt: 396 Z-score: 199.0 bits: 47.4 E(85289): 0.00024
Smith-Waterman score: 534; 45.8% identity (57.6% similar) in 177 aa overlap (45-220:108-281)
20 30 40 50 60 70
pF1KB6 PLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQ
.:. : : : .:::: : :: : ::
XP_011 TKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQ
80 90 100 110 120 130
80 90 100 110 120 130
pF1KB6 AGMPGQAGPVGPKGDNGSVGEPGPKGDTG-PSGPPGPPGVPGPAGREGPLGKQGNIGPQG
:.:: :: :: : : :. .:. . : : .:::: : : : .: :: :
XP_011 PGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMG---PSGPRGLPGPPG
140 150 160 170 180 190
140 150 160 170 180 190
pF1KB6 KPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQG
:::.: :: :: : :: .: : :: :: :. : :: : :: : : : .: .:
XP_011 APGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARG
200 210 220 230 240 250
200 210 220 230 240 250
pF1KB6 SPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVEL
::. : ::.:: .:. : ::::..:
XP_011 LPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPG
260 270 280 290 300 310
>>NP_000079 (OMIM: 114000,120150,130000,130060,166200,16 (1464 aa)
initn: 2177 init1: 618 opt: 660 Z-score: 316.0 bits: 69.1 E(85289): 7.3e-11
Smith-Waterman score: 660; 51.3% identity (60.3% similar) in 199 aa overlap (44-236:531-728)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAG
:.:::: : : : : : : :: ::
NP_000 VAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAG
510 520 530 540 550 560
80 90 100 110 120 130
pF1KB6 QAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQG
: : :: :: : .:. : .: ::::: .: : : ::::: : :: ::.:. : ::
NP_000 QDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG
570 580 590 600 610 620
140 150 160 170 180 190
pF1KB6 KPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQG
::: : :: .:: : : : : : ::: :: : :::.::::. :: : .:: : .:
NP_000 PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG
630 640 650 660 670 680
200 210 220 230 240
pF1KB6 SPGARG---PPGLKGDKGI---PGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQ
:: :: ::: : .: ::. ::::..: : : : . .:::
NP_000 FPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPG-APGSQGAPGLQGMPGERGAAGLP
690 700 710 720 730
250 260 270 280 290 300
pF1KB6 YKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAK
NP_000 GPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP
740 750 760 770 780 790
>--
initn: 1116 init1: 570 opt: 593 Z-score: 286.3 bits: 63.6 E(85289): 3.3e-09
Smith-Waterman score: 594; 50.3% identity (61.4% similar) in 189 aa overlap (44-220:234-413)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPG---LPG
:.: ::: :. : ::.: .: :: :::
NP_000 PPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPG
210 220 230 240 250 260
80 90 100 110 120
pF1KB6 AAGQAGMPG------QAGPVGPKGDNGSVGEPGPKGDTGPSGPPGP---PGVPGPAGREG
:. :. : .:::.::::. :: :: : :. :: : :: ::.::::: .:
NP_000 MKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARG
270 280 290 300 310 320
130 140 150 160 170 180
pF1KB6 PLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTG
: : :: ::: : ::: ::. :..::.: :::.: :: : .:: :. :
NP_000 NDGATGAAGP---PGPTGPAGP------PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPG
330 340 350 360 370
190 200 210 220 230 240
pF1KB6 AAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHL
: ::: :: :.::: : :: :: .: :: :: : :
NP_000 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSG
380 390 400 410 420 430
250 260 270 280 290 300
pF1KB6 QAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQ
NP_000 EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRG
440 450 460 470 480 490
>--
initn: 2131 init1: 579 opt: 585 Z-score: 282.7 bits: 63.0 E(85289): 5.2e-09
Smith-Waterman score: 607; 50.0% identity (60.9% similar) in 184 aa overlap (46-220:809-992)
20 30 40 50 60 70
pF1KB6 LGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQA
: : : : .: : ::.:: :: :.:
NP_000 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDA
780 790 800 810 820 830
80 90 100 110 120 130
pF1KB6 GMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKP
: :: :::.:: : :.:: :: :: : .:::: : :: ::: :: : .:: :: : :
NP_000 GPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP
840 850 860 870 880 890
140 150 160 170 180
pF1KB6 GPKGEAG---PKGEVGAPGMQGSAGARGLAGPKGERGVPGERG------VPGNTGAAGSA
:: :. : :.::.: : : .: : :: ::.: :: : .:: : ::.
NP_000 GPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQR
900 910 920 930 940 950
190 200 210 220 230 240
pF1KB6 GAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFS
:..: :. : :: ::: : .: :: .: .: ::
NP_000 GVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAP
960 970 980 990 1000 1010
250 260 270 280 290 300
pF1KB6 QYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVA
NP_000 GAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPV
1020 1030 1040 1050 1060 1070
>--
initn: 3511 init1: 545 opt: 567 Z-score: 274.7 bits: 61.5 E(85289): 1.5e-08
Smith-Waterman score: 567; 48.6% identity (58.2% similar) in 177 aa overlap (46-222:1022-1192)
20 30 40 50 60 70
pF1KB6 LGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQA
: ::::: : .: ::: : : ::: :
NP_000 GERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAP
1000 1010 1020 1030 1040 1050
80 90 100 110 120 130
pF1KB6 GMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKP
: :: .::.: .:: : .: :: : .:: : :: : :: : .: :.::. : .:.
NP_000 GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR
1060 1070 1080 1090 1100 1110
140 150 160 170 180 190
pF1KB6 GPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSP
: .: :: : :.:: :: .:: : ::: :: :: :.::. : : : .:: :
NP_000 GFSGLQGPPGPPGSPGEQGPSGASGPAGP---RGPPGSAGAPGKDGLNGLPGPIGP---P
1120 1130 1140 1150 1160
200 210 220 230 240 250
pF1KB6 GARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFP
: :: : : : :: : : : :
NP_000 GPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVR
1170 1180 1190 1200 1210 1220
>--
initn: 405 init1: 405 opt: 418 Z-score: 208.6 bits: 49.2 E(85289): 7e-05
Smith-Waterman score: 440; 51.5% identity (62.1% similar) in 132 aa overlap (71-202:414-530)
50 60 70 80 90 100
pF1KB6 SSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKG
: : .: : .:: ::::..: : :: ::
NP_000 PAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKG
390 400 410 420 430 440
110 120 130 140 150 160
pF1KB6 DTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARG
::: .: ::: :: :: :: :..:. : .:.::: : :: :: :.:: .: :: :
NP_000 DTGAKGEPGPVGVQGP---PGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG
450 460 470 480 490 500
170 180 190 200 210 220
pF1KB6 LAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESG
.::::: :::: : : ::.:::: : ::
NP_000 VAGPKGP---AGERGSP---------GPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG
510 520 530 540
230 240 250 260 270 280
pF1KB6 LPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLL
NP_000 PDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVG
550 560 570 580 590 600
>>XP_011532990 (OMIM: 610043) PREDICTED: collagen alpha- (557 aa)
initn: 1078 init1: 586 opt: 630 Z-score: 306.7 bits: 66.0 E(85289): 2.4e-10
Smith-Waterman score: 630; 43.6% identity (59.2% similar) in 218 aa overlap (19-236:100-312)
10 20 30 40
pF1KB6 MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLP
:.. : . : :: :. . : :
XP_011 EERELLRRAGPPGALDAWAEPHLERLLREKLDGLAKIRTAREAPSECVCPPGPPGRRGKP
70 80 90 100 110 120
50 60 70 80 90 100
pF1KB6 GRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPP
:: : : :: : : ::::: :. : ::. :: : .:..:..: ::: : : :::
XP_011 GRRGDPGPPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPP
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB6 GPPGVPGPAGREGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGER
: : :: : .:: : .:. : .:. :::: ::::: :.:: .:. :. . :: : .
XP_011 GDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPK
190 200 210 220 230 240
170 180 190 200 210 220
pF1KB6 GVPGERGVPGNTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLR
: :: : : : : :: ::.: :: :: : : .: :: :: .:.. . : .
XP_011 GEPGSMG-P--RGENGVDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVVIDYDG--
250 260 270 280 290 300
230 240 250 260 270 280
pF1KB6 QQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQL
. ..::.:
XP_011 RILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGE
310 320 330 340 350 360
>--
initn: 641 init1: 344 opt: 433 Z-score: 219.3 bits: 49.8 E(85289): 1.8e-05
Smith-Waterman score: 529; 43.9% identity (59.2% similar) in 196 aa overlap (44-229:331-514)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAG
: :::: : ::..::.:.::::: ::
XP_011 DYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGP--
310 320 330 340 350
80 90 100 110 120
pF1KB6 QAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSG----------PPGPPGVPGPAGREGPL
::. :.:: .: .: :. : : ::... .. ::::: ::: : :.
XP_011 -AGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPG---PM
360 370 380 390 400 410
130 140 150 160 170 180
pF1KB6 GKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAA
: :: ::.: : ::: : .:: : :. : .: : : :.:: .: : :
XP_011 GLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVG------PPGLIGLPGTKGEKGRPGEP
420 430 440 450 460
190 200 210 220 230 240
pF1KB6 GSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQA
: : ::.: : :. : ::..:.:: ::.::..: : .: :
XP_011 GLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVENPTCGGRRG
470 480 490 500 510 520
250 260 270 280 290 300
pF1KB6 AFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQL
XP_011 APGWRGPARGNGPCPAGPDGLPVPGCWHK
530 540 550
>>NP_000081 (OMIM: 120180,130020,130050) collagen alpha- (1466 aa)
initn: 3316 init1: 629 opt: 638 Z-score: 306.2 bits: 67.3 E(85289): 2.6e-10
Smith-Waterman score: 638; 49.7% identity (62.3% similar) in 183 aa overlap (46-222:531-713)
20 30 40 50 60 70
pF1KB6 LGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQA
: :: : : : : : :: ::. :..
NP_000 GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES
510 520 530 540 550 560
80 90 100 110 120 130
pF1KB6 GMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKP
: :: :: ::.:. : .: :::::. : : : : :: : .:: ::.:. :::: :
NP_000 GRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPP
570 580 590 600 610 620
140 150 160 170 180 190
pF1KB6 GPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSP
:: : .: ::..: :: :: : : .:: :: : ::: : :..:: :. :. : :.:
NP_000 GPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAP
630 640 650 660 670 680
200 210 220 230 240
pF1KB6 GARGPPGLKGDKGI------PGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYK
: :::::: : :. :: .:.:: .: :
NP_000 GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPK
690 700 710 720 730 740
250 260 270 280 290 300
pF1KB6 KVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNE
NP_000 GDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGER
750 760 770 780 790 800
>--
initn: 2545 init1: 562 opt: 611 Z-score: 294.3 bits: 65.1 E(85289): 1.2e-09
Smith-Waterman score: 611; 50.8% identity (60.5% similar) in 185 aa overlap (45-220:170-354)
20 30 40 50 60 70
pF1KB6 PLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQ
.: :: : : :: : .: :: ::. :
NP_000 ICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGY
140 150 160 170 180 190
80 90 100 110 120
pF1KB6 AG---MPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPG---VPGPAGREGPLGKQGN
: :::::: :: : :..: :: : : :: :: :: .::: : .:: : :
NP_000 QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF
200 210 220 230 240 250
130 140 150 160 170 180
pF1KB6 IGPQGKPGPKGEAGPKGEVGAPGMQGSAG---ARGLAGPKGERGVPGERGVPGNTGAAGS
: .:. : :. : :::.::::..: : : :: : ::.::::: :: ::::.
NP_000 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA
260 270 280 290 300 310
190 200 210 220 230 240
pF1KB6 AGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAF
: : .:: : :::: : :.::. ::::: :
NP_000 RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGA
320 330 340 350 360 370
250 260 270 280 290 300
pF1KB6 SQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVV
NP_000 QGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGA
380 390 400 410 420 430
>--
initn: 1621 init1: 598 opt: 598 Z-score: 288.5 bits: 64.0 E(85289): 2.5e-09
Smith-Waterman score: 598; 48.6% identity (61.5% similar) in 179 aa overlap (44-222:979-1157)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAG
::: :: .: .:..:: : .: ::: :.::
NP_000 IAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAG
950 960 970 980 990 1000
80 90 100 110 120 130
pF1KB6 QAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQG
. : :. : : : .:: : : .:..: : :: :: ::: : :: ::.:. : .:
NP_000 EPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESG
1010 1020 1030 1040 1050 1060
140 150 160 170 180 190
pF1KB6 KPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQG
:: : :: : :::: :: : .: .: .: :. :.:: ::: :: :: : : ::
NP_000 PAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQG
1070 1080 1090 1100 1110 1120
200 210 220 230 240 250
pF1KB6 SPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVEL
. :. :: : .: : : : : :: :
NP_000 AIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPG
1130 1140 1150 1160 1170 1180
>--
initn: 3482 init1: 559 opt: 587 Z-score: 283.6 bits: 63.1 E(85289): 4.7e-09
Smith-Waterman score: 614; 48.6% identity (61.1% similar) in 185 aa overlap (44-222:745-929)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAG
: : :: :: :..:::: : : :: ::
NP_000 PPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG
720 730 740 750 760 770
80 90 100 110 120 130
pF1KB6 QAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQG
: : :..: : : : : :: .:.::: :: : ::.:: :. : :..: : .:
NP_000 QPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKG
780 790 800 810 820 830
140 150 160 170 180 190
pF1KB6 KPGPKGEAGP---KGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMG
. :: : ::: .: .: :: :: : :: : : : :: ::.:: :. :. : :
NP_000 EGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG
840 850 860 870 880 890
200 210 220 230 240
pF1KB6 PQGSPGARGPPGLKGDKGIPGDKGA---KGESGLPDVASLRQQVEALQGQVQHLQAAFSQ
:.:::: :::: :. : ::. :. ::..: :
NP_000 PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITG
900 910 920 930 940 950
250 260 270 280 290 300
pF1KB6 YKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAK
NP_000 ARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG
960 970 980 990 1000 1010
>--
initn: 1713 init1: 467 opt: 524 Z-score: 255.6 bits: 58.0 E(85289): 1.7e-07
Smith-Waterman score: 524; 46.8% identity (57.3% similar) in 171 aa overlap (59-220:355-525)
30 40 50 60 70 80
pF1KB6 RTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKG
: : :. : :: :. : :.:: :: :
NP_000 ARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG
330 340 350 360 370 380
90 100 110 120 130 140
pF1KB6 DNGSVGEPGPKGDTGPSGPPGPPGV------PGPAGREGPLGKQGNIGPQGKPGPKGEAG
: : :: ::. ::.: :: ::. ::::: .: : .:. : :: : ::: :
NP_000 PPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPG
390 400 410 420 430 440
150 160 170 180 190
pF1KB6 PKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTG---AAGSAGAMGPQGSPGARG
:.:: : :. : ::.: : : : :: :.:: .: : : : ::.: :: .:
NP_000 PRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKG
450 460 470 480 490 500
200 210 220 230 240 250
pF1KB6 PPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQS
: : .: : : .:: :: :
NP_000 PAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPG
510 520 530 540 550 560
>>XP_011532994 (OMIM: 610043) PREDICTED: collagen alpha- (472 aa)
initn: 1058 init1: 581 opt: 625 Z-score: 305.2 bits: 65.5 E(85289): 2.9e-10
Smith-Waterman score: 626; 42.4% identity (57.6% similar) in 231 aa overlap (15-236:2-227)
10 20 30 40 50
pF1KB6 MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGR---------D
: :.. : . : :: :. . : ::: .
XP_011 MPNQKLDGLAKIRTAREAPSECVCPPGPPGRRGKPGRRGDPGPPGQS
10 20 30 40
60 70 80 90 100 110
pF1KB6 GRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPP
:::: :: : : ::::: :. : ::. :: : .:..:..: ::: : : ::::
XP_011 GRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 GVPGPAGREGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVP
: :: : .:: : .:. : .:. :::: ::::: :.:: .:. :. . :: : .: :
XP_011 GKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 GERGVPGNTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQV
: : : : : :: ::.: :: :: : : .: :: :: .:.. . : . . .
XP_011 GSMG-P--RGENGVDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVVIDYDG--RIL
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 EALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASP
.::.:
XP_011 DALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGE
230 240 250 260 270 280
>--
initn: 641 init1: 344 opt: 433 Z-score: 220.0 bits: 49.7 E(85289): 1.6e-05
Smith-Waterman score: 529; 43.9% identity (59.2% similar) in 196 aa overlap (44-229:246-429)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAG
: :::: : ::..::.:.::::: ::
XP_011 DYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGP--
220 230 240 250 260 270
80 90 100 110 120
pF1KB6 QAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSG----------PPGPPGVPGPAGREGPL
::. :.:: .: .: :. : : ::... .. ::::: ::: : :.
XP_011 -AGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPG---PM
280 290 300 310 320
130 140 150 160 170 180
pF1KB6 GKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAA
: :: ::.: : ::: : .:: : :. : .: : : :.:: .: : :
XP_011 GLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVG------PPGLIGLPGTKGEKGRPGEP
330 340 350 360 370 380
190 200 210 220 230 240
pF1KB6 GSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQA
: : ::.: : :. : ::..:.:: ::.::..: : .: :
XP_011 GLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVENPTCGGRRG
390 400 410 420 430 440
250 260 270 280 290 300
pF1KB6 AFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQL
XP_011 APGWRGPARGNGPCPAGPDGLPVPGCWHK
450 460 470
>>NP_775736 (OMIM: 610043) collagen alpha-1(XXIII) chain (540 aa)
initn: 1058 init1: 581 opt: 625 Z-score: 304.7 bits: 65.6 E(85289): 3.1e-10
Smith-Waterman score: 625; 46.6% identity (63.2% similar) in 193 aa overlap (44-236:134-321)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAG
. : ::..:::: :: : : ::::: :
NP_775 AKIRTAREAPSECVCPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKG
110 120 130 140 150 160
80 90 100 110 120 130
pF1KB6 QAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQG
. : ::. :: : .:..:..: ::: : : :::: : :: : .:: : .:. : .:
NP_775 EKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDG
170 180 190 200 210 220
140 150 160 170 180 190
pF1KB6 KPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQG
. :::: ::::: :.:: .:. :. . :: : .: :: : : : : :: ::.:
NP_775 EMGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMG-P--RGENGVDGAPGPKG
230 240 250 260 270 280
200 210 220 230 240 250
pF1KB6 SPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVEL
:: :: : : .: :: :: .:.. . : . . ..::.:
NP_775 EPGHRGTDGAAGPRGAPGLKGEQGDTVVIDYDG--RILDALKGPPGPQGPPGPPGIPGAK
290 300 310 320 330
260 270 280 290 300 310
pF1KB6 FPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFL
NP_775 GELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASD
340 350 360 370 380 390
>--
initn: 982 init1: 341 opt: 429 Z-score: 217.6 bits: 49.5 E(85289): 2.2e-05
Smith-Waterman score: 529; 43.9% identity (59.2% similar) in 196 aa overlap (44-229:340-523)
20 30 40 50 60 70
pF1KB6 QPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAG
: :::: : ::..::.:.::::: ::
NP_775 DYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGP--
310 320 330 340 350 360
80 90 100 110 120
pF1KB6 QAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSG----------PPGPPGVPGPAGREGPL
::. :.:: .: .: :. : : ::... .. ::::: ::: : :.
NP_775 -AGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPG---PM
370 380 390 400 410 420
130 140 150 160 170 180
pF1KB6 GKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAA
: :: ::.: : ::: : .:: : :. : .: : : :.:: .: : :
NP_775 GLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVG------PPGLIGLPGTKGEKGRPGEP
430 440 450 460 470
190 200 210 220 230 240
pF1KB6 GSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQA
: : ::.: : :. : ::..:.:: ::.::..: : .: :
NP_775 GLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVPGC
480 490 500 510 520 530
250 260 270 280 290 300
pF1KB6 AFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQL
NP_775 WHK
540
375 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:47:22 2016 done: Fri Nov 4 15:47:24 2016
Total Scan time: 10.400 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]