Result of FASTA (ccds) for
pF1KB6537
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6537, 367 aa
1>>>pF1KB6537 367 - 367 aa - 367 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1950+/-0.000742; mu= 8.9129+/- 0.045
mean_var=112.8601+/-22.071, 0's: 0 Z-trim(111.8): 11 B-trim: 0 in 0/55
Lambda= 0.120727
statistics sampled from 12671 (12680) to 12671 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.39), width: 16
Scan time: 2.480
The best scores are: opt bits E(32554)
CCDS3315.1 PCYT1A gene_id:5130|Hs108|chr3 ( 367) 2472 440.8 8.7e-124
CCDS55392.1 PCYT1B gene_id:9468|Hs108|chrX ( 351) 1654 298.4 6.5e-81
CCDS14213.1 PCYT1B gene_id:9468|Hs108|chrX ( 369) 1647 297.1 1.6e-80
CCDS55391.1 PCYT1B gene_id:9468|Hs108|chrX ( 330) 1533 277.3 1.4e-74
CCDS82220.1 PCYT2 gene_id:5833|Hs108|chr17 ( 367) 344 70.2 3.2e-12
CCDS11791.1 PCYT2 gene_id:5833|Hs108|chr17 ( 389) 344 70.2 3.4e-12
CCDS54178.1 PCYT2 gene_id:5833|Hs108|chr17 ( 407) 344 70.2 3.6e-12
>>CCDS3315.1 PCYT1A gene_id:5130|Hs108|chr3 (367 aa)
initn: 2472 init1: 2472 opt: 2472 Z-score: 2335.9 bits: 440.8 E(32554): 8.7e-124
Smith-Waterman score: 2472; 100.0% identity (100.0% similar) in 367 aa overlap (1-367:1-367)
10 20 30 40 50 60
pF1KB6 MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD
310 320 330 340 350 360
pF1KB6 ISEDEED
:::::::
CCDS33 ISEDEED
>>CCDS55392.1 PCYT1B gene_id:9468|Hs108|chrX (351 aa)
initn: 1606 init1: 1606 opt: 1654 Z-score: 1566.2 bits: 298.4 E(32554): 6.5e-81
Smith-Waterman score: 1654; 72.3% identity (87.6% similar) in 347 aa overlap (26-367:10-349)
10 20 30 40 50 60
pF1KB6 MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV
:::. .. : . : ::::.:: . . . :.
CCDS55 MVGHQECIMEEDNRAPQLWRKT--LTAPAPFADETNCQCQAPHE
10 20 30 40
70 80 90 100 110 120
pF1KB6 RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN
..:. .: ::: .::::::::::::::::::::::::::.::::.::.::::::.:::.
CCDS55 KLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD
::::::::: :::.:..::::::::.:.:::::::::: .:.::::::::::::::::::
CCDS55 FKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::.:
CCDS55 VYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK
..:..:::.:.:::.:::.:::::..::::: :::::::::::::::.:::.:::.:: :
CCDS55 RFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWK
230 240 250 260 270 280
310 320 330 340 350
pF1KB6 HMLKEGKGRMLQAISPKQSPSSSPTRERSPS----PSFRW-PFSGKTSPPCSPANLSRHK
.:..: ..:::::.:::::: ::::: :::: :.: : :. ::::: :: :
CCDS55 QMFQERSSRMLQALSPKQSPVSSPTRSRSPSRSPSPTFSWLPL--KTSPPSSPKAAS---
290 300 310 320 330
360
pF1KB6 AAAYDISEDEED
:. ..:: .::
CCDS55 ASISSMSEGDEDEK
340 350
>>CCDS14213.1 PCYT1B gene_id:9468|Hs108|chrX (369 aa)
initn: 1606 init1: 1606 opt: 1647 Z-score: 1559.3 bits: 297.1 E(32554): 1.6e-80
Smith-Waterman score: 1647; 74.4% identity (89.2% similar) in 332 aa overlap (41-367:41-367)
20 30 40 50 60 70
pF1KB6 ARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEASRG
: ::::.:: . . . :. ..:. .: :
CCDS14 ETGIPKSLSNEPPSETMEEIEHTCPQPRLTLTAPAPFADETNCQCQAPHEKLTIAQARLG
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB6 TPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNEN
:: .::::::::::::::::::::::::::.::::.::.::::::.:::.:::::::::
CCDS14 TPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEA
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB6 ERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGM
:::.:..::::::::.:.:::::::::: .:.::::::::::::::::::::::::::::
CCDS14 ERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGM
140 150 160 170 180 190
200 210 220 230 240 250
pF1KB6 FAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVK
:.::::::::::::::::::::::::::::::::::::::::::::::.:..:..:::.:
CCDS14 FVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMK
200 210 220 230 240 250
260 270 280 290 300 310
pF1KB6 KKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALKHMLKEGKGRM
.:::.:::.:::::..::::: :::::::::::::::.:::.:::.:: :.:..: ..::
CCDS14 EKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRM
260 270 280 290 300 310
320 330 340 350 360
pF1KB6 LQAISPKQSPSSSPTRERSPS----PSFRW-PFSGKTSPPCSPANLSRHKAAAYDISEDE
:::.:::::: ::::: :::: :.: : :. ::::: :: : :. ..:: .
CCDS14 LQALSPKQSPVSSPTRSRSPSRSPSPTFSWLPL--KTSPPSSPKAAS---ASISSMSEGD
320 330 340 350 360
pF1KB6 ED
::
CCDS14 EDEK
>>CCDS55391.1 PCYT1B gene_id:9468|Hs108|chrX (330 aa)
initn: 1622 init1: 1530 opt: 1533 Z-score: 1452.7 bits: 277.3 E(32554): 1.4e-74
Smith-Waterman score: 1533; 77.8% identity (93.4% similar) in 288 aa overlap (41-328:41-328)
20 30 40 50 60 70
pF1KB6 ARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEASRG
: ::::.:: . . . :. ..:. .: :
CCDS55 ETGIPKSLSNEPPSETMEEIEHTCPQPRLTLTAPAPFADETNCQCQAPHEKLTIAQARLG
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB6 TPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNEN
:: .::::::::::::::::::::::::::.::::.::.::::::.:::.:::::::::
CCDS55 TPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEA
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB6 ERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGM
:::.:..::::::::.:.:::::::::: .:.::::::::::::::::::::::::::::
CCDS55 ERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGM
140 150 160 170 180 190
200 210 220 230 240 250
pF1KB6 FAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVK
:.::::::::::::::::::::::::::::::::::::::::::::::.:..:..:::.:
CCDS55 FVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMK
200 210 220 230 240 250
260 270 280 290 300 310
pF1KB6 KKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALKHMLKEGKGRM
.:::.:::.:::::..::::: :::::::::::::::.:::.:::.:: :.:..: ..::
CCDS55 EKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRM
260 270 280 290 300 310
320 330 340 350 360
pF1KB6 LQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYDISEDEED
:::.:::::: .: .: :
CCDS55 LQALSPKQSPLKSWARCRDF
320 330
>>CCDS82220.1 PCYT2 gene_id:5833|Hs108|chr17 (367 aa)
initn: 359 init1: 254 opt: 344 Z-score: 332.8 bits: 70.2 E(32554): 3.2e-12
Smith-Waterman score: 344; 40.8% identity (66.9% similar) in 142 aa overlap (70-210:16-154)
40 50 60 70 80 90
pF1KB6 GLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQA
: .: :::. :: .:. : ::. : ::
CCDS82 MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQA
10 20 30 40
100 110 120 130 140 150
pF1KB6 KNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLA
. . . :::::: .:: . :: :....::: :: ..::::: ::.. : : :
CCDS82 RAM--GDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLD
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB6 EHRIDFVAH-DDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYAR
.. :: .: .:: . : : .:...:.:: . .::.:.::.:.. :..
CCDS82 KYNCDFCVHGNDITLTVDGRD-TYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHS
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB6 RNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKW
CCDS82 SQEMSSEYREYADSFGKCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAF
170 180 190 200 210 220
>>CCDS11791.1 PCYT2 gene_id:5833|Hs108|chr17 (389 aa)
initn: 359 init1: 254 opt: 344 Z-score: 332.4 bits: 70.2 E(32554): 3.4e-12
Smith-Waterman score: 344; 40.8% identity (66.9% similar) in 142 aa overlap (70-210:16-154)
40 50 60 70 80 90
pF1KB6 GLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQA
: .: :::. :: .:. : ::. : ::
CCDS11 MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQA
10 20 30 40
100 110 120 130 140 150
pF1KB6 KNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLA
. . . :::::: .:: . :: :....::: :: ..::::: ::.. : : :
CCDS11 RAM--GDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLD
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB6 EHRIDFVAH-DDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYAR
.. :: .: .:: . : : .:...:.:: . .::.:.::.:.. :..
CCDS11 KYNCDFCVHGNDITLTVDGRD-TYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHS
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB6 RNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKW
CCDS11 SQEMSSEYREYADSFGKCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAF
170 180 190 200 210 220
>>CCDS54178.1 PCYT2 gene_id:5833|Hs108|chr17 (407 aa)
initn: 337 init1: 254 opt: 344 Z-score: 332.1 bits: 70.2 E(32554): 3.6e-12
Smith-Waterman score: 344; 40.8% identity (66.9% similar) in 142 aa overlap (70-210:16-154)
40 50 60 70 80 90
pF1KB6 GLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQA
: .: :::. :: .:. : ::. : ::
CCDS54 MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQA
10 20 30 40
100 110 120 130 140 150
pF1KB6 KNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLA
. . . :::::: .:: . :: :....::: :: ..::::: ::.. : : :
CCDS54 RAM--GDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLD
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB6 EHRIDFVAH-DDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYAR
.. :: .: .:: . : : .:...:.:: . .::.:.::.:.. :..
CCDS54 KYNCDFCVHGNDITLTVDGRD-TYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHS
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB6 RNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKW
CCDS54 SQEMSSEYREYADSFGKPPHPIPAGDILSSEGCSQCPGGRNPWTGVSQFLQTSQKIIQFA
170 180 190 200 210 220
367 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:26:00 2016 done: Sat Nov 5 11:26:00 2016
Total Scan time: 2.480 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]