Result of FASTA (omim) for
pF1KB6532
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6532, 389 aa
1>>>pF1KB6532 389 - 389 aa - 389 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8637+/-0.000365; mu= 9.4577+/- 0.023
mean_var=101.3513+/-19.712, 0's: 0 Z-trim(115.1): 184 B-trim: 94 in 1/54
Lambda= 0.127397
statistics sampled from 25086 (25273) to 25086 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.296), width: 16
Scan time: 7.360
The best scores are: opt bits E(85289)
NP_002797 (OMIM: 602708) 26S protease regulatory s ( 403) 2549 479.0 8.4e-135
XP_016876961 (OMIM: 602708) PREDICTED: 26S proteas ( 288) 1904 360.4 3e-99
NP_001186092 (OMIM: 601681) 26S protease regulator ( 398) 1141 220.2 6.6e-57
NP_002796 (OMIM: 601681) 26S protease regulatory s ( 406) 1141 220.3 6.7e-57
NP_002794 (OMIM: 154365) 26S protease regulatory s ( 433) 1077 208.5 2.5e-53
NP_006494 (OMIM: 602707) 26S protease regulatory s ( 418) 1029 199.7 1.1e-50
NP_002793 (OMIM: 602706) 26S protease regulatory s ( 440) 1021 198.2 3.1e-50
NP_001317141 (OMIM: 602706) 26S protease regulator ( 367) 1019 197.8 3.5e-50
XP_016876959 (OMIM: 602706) PREDICTED: 26S proteas ( 367) 1019 197.8 3.5e-50
NP_694546 (OMIM: 602707) 26S protease regulatory s ( 387) 1000 194.3 4.1e-49
NP_002795 (OMIM: 186852) 26S protease regulatory s ( 439) 944 184.1 5.7e-46
XP_016873515 (OMIM: 186852) PREDICTED: 26S proteas ( 461) 880 172.3 2.1e-42
NP_009057 (OMIM: 167320,601023,613954,616687) tran ( 806) 678 135.3 5.1e-31
XP_011523903 (OMIM: 604581,610246,614487) PREDICTE ( 730) 659 131.8 5.2e-30
NP_006787 (OMIM: 604581,610246,614487) AFG3-like p ( 797) 659 131.8 5.6e-30
NP_003110 (OMIM: 602783,607259) paraplegin isoform ( 795) 627 125.9 3.3e-28
XP_006721327 (OMIM: 602783,607259) PREDICTED: para ( 809) 627 125.9 3.4e-28
XP_016879087 (OMIM: 602783,607259) PREDICTED: para ( 561) 619 124.4 6.8e-28
XP_016879086 (OMIM: 602783,607259) PREDICTED: para ( 618) 619 124.4 7.4e-28
NP_001304728 (OMIM: 613940,616577) spermatogenesis ( 695) 619 124.4 8.2e-28
XP_011529981 (OMIM: 613940,616577) PREDICTED: sper ( 790) 619 124.4 9.1e-28
XP_016863317 (OMIM: 613940,616577) PREDICTED: sper ( 819) 619 124.4 9.4e-28
NP_001332785 (OMIM: 613940,616577) spermatogenesis ( 892) 619 124.5 1e-27
NP_660208 (OMIM: 613940,616577) spermatogenesis-as ( 893) 619 124.5 1e-27
XP_016863319 (OMIM: 613940,616577) PREDICTED: sper ( 593) 604 121.6 4.8e-27
XP_016863318 (OMIM: 613940,616577) PREDICTED: sper ( 765) 603 121.5 6.8e-27
XP_016863316 (OMIM: 613940,616577) PREDICTED: sper ( 823) 603 121.5 7.3e-27
XP_016863315 (OMIM: 613940,616577) PREDICTED: sper ( 859) 603 121.5 7.6e-27
XP_011529980 (OMIM: 613940,616577) PREDICTED: sper ( 916) 603 121.5 8e-27
XP_016863314 (OMIM: 613940,616577) PREDICTED: sper ( 917) 603 121.5 8e-27
XP_011515297 (OMIM: 611941) PREDICTED: ATPase fami ( 953) 602 121.3 9.4e-27
XP_016856875 (OMIM: 602426) PREDICTED: nuclear val ( 738) 599 120.7 1.1e-26
NP_996671 (OMIM: 602426) nuclear valosin-containin ( 750) 599 120.7 1.1e-26
NP_001230076 (OMIM: 602426) nuclear valosin-contai ( 765) 599 120.7 1.1e-26
XP_016856872 (OMIM: 602426) PREDICTED: nuclear val ( 812) 599 120.8 1.2e-26
XP_011515296 (OMIM: 611941) PREDICTED: ATPase fami (1260) 602 121.4 1.2e-26
NP_002524 (OMIM: 602426) nuclear valosin-containin ( 856) 599 120.8 1.3e-26
XP_016856868 (OMIM: 602426) PREDICTED: nuclear val ( 890) 599 120.8 1.3e-26
NP_054828 (OMIM: 611941) ATPase family AAA domain- (1390) 602 121.4 1.3e-26
XP_016867808 (OMIM: 214100,234580,601539,602136) P ( 700) 594 119.8 2e-26
XP_011531234 (OMIM: 615347) PREDICTED: ATPase fami ( 791) 593 119.7 2.5e-26
XP_011531233 (OMIM: 615347) PREDICTED: ATPase fami ( 837) 593 119.7 2.6e-26
XP_011531232 (OMIM: 615347) PREDICTED: ATPase fami ( 841) 593 119.7 2.7e-26
XP_011531231 (OMIM: 615347) PREDICTED: ATPase fami ( 843) 593 119.7 2.7e-26
XP_011531230 (OMIM: 615347) PREDICTED: ATPase fami ( 849) 593 119.7 2.7e-26
NP_001269607 (OMIM: 214100,234580,601539,602136) p (1075) 594 119.9 2.9e-26
NP_001269606 (OMIM: 214100,234580,601539,602136) p (1226) 594 119.9 3.2e-26
XP_006712094 (OMIM: 615347) PREDICTED: ATPase fami (1067) 593 119.7 3.3e-26
XP_011531227 (OMIM: 615347) PREDICTED: ATPase fami (1079) 593 119.7 3.3e-26
XP_011531226 (OMIM: 615347) PREDICTED: ATPase fami (1083) 593 119.7 3.3e-26
>>NP_002797 (OMIM: 602708) 26S protease regulatory subun (403 aa)
initn: 2549 init1: 2549 opt: 2549 Z-score: 2541.1 bits: 479.0 E(85289): 8.4e-135
Smith-Waterman score: 2549; 100.0% identity (100.0% similar) in 389 aa overlap (1-389:15-403)
10 20 30 40
pF1KB6 MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSEND
::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAIPGIPYERRLLIMADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSEND
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 LKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLT
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 IMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB6 PKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQ
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB6 PCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB6 PALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNV
310 320 330 340 350 360
350 360 370 380
pF1KB6 CTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
:::::::::::::::::::::::::::::::::::::::::::
NP_002 CTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
370 380 390 400
>>XP_016876961 (OMIM: 602708) PREDICTED: 26S protease re (288 aa)
initn: 1904 init1: 1904 opt: 1904 Z-score: 1902.7 bits: 360.4 E(85289): 3e-99
Smith-Waterman score: 1904; 100.0% identity (100.0% similar) in 288 aa overlap (102-389:1-288)
80 90 100 110 120 130
pF1KB6 KATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVS
::::::::::::::::::::::::::::::
XP_016 MTTLTIMRYLPREVDPLVYNMSHEDPGNVS
10 20 30
140 150 160 170 180 190
pF1KB6 YSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQL
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB6 DCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADR
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB6 EIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLD
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB6 ILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAV
220 230 240 250 260 270
380
pF1KB6 RKVADSKKLESKLDYKPV
::::::::::::::::::
XP_016 RKVADSKKLESKLDYKPV
280
>>NP_001186092 (OMIM: 601681) 26S protease regulatory su (398 aa)
initn: 1136 init1: 1136 opt: 1141 Z-score: 1142.6 bits: 220.2 E(85289): 6.6e-57
Smith-Waterman score: 1141; 50.3% identity (76.1% similar) in 356 aa overlap (26-379:34-389)
10 20 30 40 50
pF1KB6 MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQ
:..:. : .::. . . ...:. :: :.
NP_001 EEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 IVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREV
::::.. . ..: .::. ..:: ...: . . :. :::: . :. . :: .:
NP_001 YVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 DPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGP
:::: : : . .: ::::..::.:..::::::. .::::. .:: ::: :::::
NP_001 DPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 PGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEI
::::::::::::: . ::.:..: .: .:.:.:::.::..::.: .::.: : :::::::
NP_001 PGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEI
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRL
:.::. :. :...: :.:::..:::::.:::.. . .:.:::::: : :: :::::::.
NP_001 DSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 DRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAI
::::.. :::.:::::::::. .. :. . :..: : .::....:::::::.:.
NP_001 DRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL
310 320 330 340 350 360
360 370 380
pF1KB6 RADHDFVVQEDFMKAVRKVA--DSKKLESKLDYKPV
: . :.:::: :: :: ::.:
NP_001 RERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
370 380 390
>>NP_002796 (OMIM: 601681) 26S protease regulatory subun (406 aa)
initn: 1136 init1: 1136 opt: 1141 Z-score: 1142.5 bits: 220.3 E(85289): 6.7e-57
Smith-Waterman score: 1141; 50.3% identity (76.1% similar) in 356 aa overlap (26-379:42-397)
10 20 30 40 50
pF1KB6 MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQ
:..:. : .::. . . ...:. :: :.
NP_002 EEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGS
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB6 IVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREV
::::.. . ..: .::. ..:: ...: . . :. :::: . :. . :: .:
NP_002 YVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKV
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB6 DPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGP
:::: : : . .: ::::..::.:..::::::. .::::. .:: ::: :::::
NP_002 DPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGP
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB6 PGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEI
::::::::::::: . ::.:..: .: .:.:.:::.::..::.: .::.: : :::::::
NP_002 PGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEI
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB6 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRL
:.::. :. :...: :.:::..:::::.:::.. . .:.:::::: : :: :::::::.
NP_002 DSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRI
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB6 DRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAI
::::.. :::.:::::::::. .. :. . :..: : .::....:::::::.:.
NP_002 DRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL
320 330 340 350 360 370
360 370 380
pF1KB6 RADHDFVVQEDFMKAVRKVA--DSKKLESKLDYKPV
: . :.:::: :: :: ::.:
NP_002 RERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
380 390 400
>>NP_002794 (OMIM: 154365) 26S protease regulatory subun (433 aa)
initn: 1104 init1: 1052 opt: 1077 Z-score: 1078.5 bits: 208.5 E(85289): 2.5e-53
Smith-Waterman score: 1078; 45.5% identity (75.1% similar) in 374 aa overlap (20-377:46-419)
10 20 30 40
pF1KB6 MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSEN----
:... ...: ....::: :.. .
NP_002 EKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPP
20 30 40 50 60 70
50 60 70 80 90
pF1KB6 ---DLKA----LQSVG--QIV--GEVLKQLTEE-KFIVKATNGPRYVVGCRRQLDKSKLK
:: : ::: :.. .... .:. :.:... . ..:: :. . ..
NP_002 ALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIE
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB6 PGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPL
: ::..: . : :: ..:: : :. :. .:.::..:: .:::..::::.: ::
NP_002 EGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB6 TNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESAR
.:: : .:: :::: ::.::::::::: :::::.. : :..:..: .:.::.::.::
NP_002 LHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGAR
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB6 LIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRV
..::.:..:: .. :.::.:::::::: ::..:...: :.:::..::.::.:::: .
NP_002 MVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNI
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB6 KMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVK
:..:::::::::::::.:::::::::...::. ..: :.:::: .. . .: .: ...
NP_002 KVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLAR
320 330 340 350 360 370
340 350 360 370 380
pF1KB6 LSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
: . .::..:.:::::::::::: . .....::..:: :: :
NP_002 LCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN
380 390 400 410 420 430
>>NP_006494 (OMIM: 602707) 26S protease regulatory subun (418 aa)
initn: 1025 init1: 975 opt: 1029 Z-score: 1031.1 bits: 199.7 E(85289): 1.1e-50
Smith-Waterman score: 1029; 41.6% identity (72.9% similar) in 387 aa overlap (3-387:33-418)
10 20 30
pF1KB6 MADPRD-KALQDYRKKLLEHKE-IDGRLKELR
.:.: . : . ::: .. : .. . . ..
NP_006 EIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 EQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKS
.. :.: :.. ......: .::. ..:. :. . .. :: .:.: : : .:.
NP_006 DEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 KLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIE
:::.. ::: . ... :: :.: .. .. .. .: :..:::.. : .:.::..:
NP_006 LLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 LPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGE
::::. ::....:: ::.: :.::::: :::.::.::: . :..::.: .:.::.::
NP_006 LPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 SARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTL
. :..:..: :... : :::.::::::. .::. :.::::.:: :.::::::::::
NP_006 GPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQN
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 HRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEA
::.:::::: :::::::::::::::::.. ::... . :.. .. .. :.: :
NP_006 VNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLED
310 320 330 340 350 360
340 350 360 370 380
pF1KB6 IVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
: : ..:::. ..: :.::.:.: .. .:. .:: :: . : . . : .. ::
NP_006 YVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEF-YK
370 380 390 400 410
>>NP_002793 (OMIM: 602706) 26S protease regulatory subun (440 aa)
initn: 1015 init1: 1015 opt: 1021 Z-score: 1022.8 bits: 198.2 E(85289): 3.1e-50
Smith-Waterman score: 1021; 42.6% identity (75.9% similar) in 373 aa overlap (13-379:59-431)
10 20 30
pF1KB6 MADPRDKALQDYRKKLLEHKEIDGRL---KEL---REQLKEL
: :::. ..: : .:. .::.: :
NP_002 VPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPL
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB6 TKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGT
.. :. .. . :... . :: . . . ... ::... : .. :. .::. :.::
NP_002 EEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGC
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 RVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNP
: :. . ... : ..:::: :. : . .:..::::..::.:..: .:::::.:
NP_002 SVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHP
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB6 ELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIR
: ....:: :::: .:::::::::::::.:::.: . .::.::.: ...::.:.. .:.:
NP_002 EYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVR
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB6 EMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMI
:.: :..: : :.:.::::::: .:.. .....::::::..:::::.::::. ::.:
NP_002 ELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVI
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB6 MATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSD
::::: .::::::.::::.::::.. ::.:... :..::.. .: .. . .. .:
NP_002 MATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKD
330 340 350 360 370 380
340 350 360 370 380
pF1KB6 GFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
..:::.. .:::::..:.: . :..::: :. ..: .:.
NP_002 DLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL
390 400 410 420 430 440
>>NP_001317141 (OMIM: 602706) 26S protease regulatory su (367 aa)
initn: 1015 init1: 1015 opt: 1019 Z-score: 1022.0 bits: 197.8 E(85289): 3.5e-50
Smith-Waterman score: 1019; 43.4% identity (77.4% similar) in 350 aa overlap (30-379:9-358)
10 20 30 40 50 60
pF1KB6 MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEV
.::.: : .. :. .. . :... . :: .
NP_001 MEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTL
10 20 30
70 80 90 100 110 120
pF1KB6 LKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVY
. . ... ::... : .. :. .::. :.:: : :. . ... : ..::::
NP_001 EEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 NMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGK
:. : . .:..::::..::.:..: .:::::.:: ....:: :::: .:::::::::
NP_001 VMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 TLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGG
::::.:::.: . .::.::.: ...::.:.. .:.::.: :..: : :.:.:::::::
NP_001 TLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 RRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIH
.:.. .....::::::..:::::.::::. ::.:::::: .::::::.::::.::::.
NP_001 KRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 IDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHD
. ::.:... :..::.. .: .. . .. .: ..:::.. .:::::..:.: .
NP_001 FPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRM
280 290 300 310 320 330
370 380
pF1KB6 FVVQEDFMKAVRKVADSKKLESKLDYKPV
:..::: :. ..: .:.
NP_001 KVTNEDFKKSKENVLYKKQEGTPEGLYL
340 350 360
>>XP_016876959 (OMIM: 602706) PREDICTED: 26S protease re (367 aa)
initn: 1015 init1: 1015 opt: 1019 Z-score: 1022.0 bits: 197.8 E(85289): 3.5e-50
Smith-Waterman score: 1019; 43.4% identity (77.4% similar) in 350 aa overlap (30-379:9-358)
10 20 30 40 50 60
pF1KB6 MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEV
.::.: : .. :. .. . :... . :: .
XP_016 MEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTL
10 20 30
70 80 90 100 110 120
pF1KB6 LKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVY
. . ... ::... : .. :. .::. :.:: : :. . ... : ..::::
XP_016 EEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 NMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGK
:. : . .:..::::..::.:..: .:::::.:: ....:: :::: .:::::::::
XP_016 VMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 TLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGG
::::.:::.: . .::.::.: ...::.:.. .:.::.: :..: : :.:.:::::::
XP_016 TLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 RRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIH
.:.. .....::::::..:::::.::::. ::.:::::: .::::::.::::.::::.
XP_016 KRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 IDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHD
. ::.:... :..::.. .: .. . .. .: ..:::.. .:::::..:.: .
XP_016 FPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRM
280 290 300 310 320 330
370 380
pF1KB6 FVVQEDFMKAVRKVADSKKLESKLDYKPV
:..::: :. ..: .:.
XP_016 KVTNEDFKKSKENVLYKKQEGTPEGLYL
340 350 360
>>NP_694546 (OMIM: 602707) 26S protease regulatory subun (387 aa)
initn: 1025 init1: 975 opt: 1000 Z-score: 1002.8 bits: 194.3 E(85289): 4.1e-49
Smith-Waterman score: 1000; 42.8% identity (72.4% similar) in 362 aa overlap (26-387:27-387)
10 20 30 40 50
pF1KB6 MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGE
:. : . ..: : . ....: .::. ..:.
NP_694 MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKEEVKRIQSIPLVIGQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 VLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLV
:. . .. :: .:.: : : .:. :::.. ::: . ... :: :.: .
NP_694 FLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 YNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTG
. .. .. .: :..:::.. : .:.::..:::::. ::....:: ::.: :.::::: :
NP_694 MMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 KTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIG
::.::.::: . :..::.: .:.::.::. :..:..: :... : :::.::::::.
NP_694 KTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 GRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKI
.::. :.::::.:: :.:::::::::: ::.:::::: :::::::::::::::::
NP_694 TKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 HIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADH
.. ::... . :.. .. .. :.: : : : ..:::. ..: :.::.:.: ..
NP_694 EFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENR
310 320 330 340 350 360
360 370 380
pF1KB6 DFVVQEDFMKAVRKVADSKKLESKLDYKPV
.:. .:: :: . : . . : .. ::
NP_694 YIVLAKDFEKAYKTVIKKDEQEHEF-YK
370 380
389 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:15:56 2016 done: Fri Nov 4 23:15:57 2016
Total Scan time: 7.360 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]