Result of FASTA (ccds) for
pF1KB6521
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6521, 363 aa
1>>>pF1KB6521 363 - 363 aa - 363 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9012+/-0.000882; mu= 13.4123+/- 0.053
mean_var=81.2246+/-15.836, 0's: 0 Z-trim(107.0): 28 B-trim: 0 in 0/52
Lambda= 0.142308
statistics sampled from 9310 (9331) to 9310 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.287), width: 16
Scan time: 2.330
The best scores are: opt bits E(32554)
CCDS3283.1 RFC4 gene_id:5984|Hs108|chr3 ( 363) 2321 486.3 1.8e-137
CCDS9185.1 RFC5 gene_id:5985|Hs108|chr12 ( 340) 738 161.2 1.2e-39
CCDS41843.2 RFC5 gene_id:5985|Hs108|chr12 ( 319) 706 154.7 1e-37
CCDS5568.1 RFC2 gene_id:5982|Hs108|chr7 ( 354) 673 147.9 1.2e-35
CCDS75618.1 RFC2 gene_id:5982|Hs108|chr7 ( 251) 443 100.6 1.5e-21
CCDS5567.1 RFC2 gene_id:5982|Hs108|chr7 ( 320) 349 81.4 1.2e-15
>>CCDS3283.1 RFC4 gene_id:5984|Hs108|chr3 (363 aa)
initn: 2321 init1: 2321 opt: 2321 Z-score: 2581.6 bits: 486.3 E(32554): 1.8e-137
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363)
10 20 30 40 50 60
pF1KB6 MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 EKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 NYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 AITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 HAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 HAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLS
310 320 330 340 350 360
pF1KB6 QNC
:::
CCDS32 QNC
>>CCDS9185.1 RFC5 gene_id:5985|Hs108|chr12 (340 aa)
initn: 714 init1: 388 opt: 738 Z-score: 825.6 bits: 161.2 E(32554): 1.2e-39
Smith-Waterman score: 738; 39.6% identity (70.7% similar) in 321 aa overlap (34-353:16-327)
10 20 30 40 50 60
pF1KB6 FLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLK
: . .::::::::. .... .........
CCDS91 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQ
10 20 30 40
70 80 90 100 110 120
pF1KB6 KSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKV
: .. ::.::.:::::::::::::: :..:. . : ::::::::.:::...: .
CCDS91 KFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 KNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYV
.::. .:. : ::.:::::::.::. :: ::::..:: ...:::::::::.
CCDS91 LSFAS-----TRTIFKK--GFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYL
110 120 130 140 150
190 200 210 220 230 240
pF1KB6 SRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAIT
:.:: : :::..::: ::. ... :: ....:.: ::..:. :: .: ::.:.:..
CCDS91 SKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALN
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 FLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLID-EGHA
.::: : .. :: .::... .: : ... . .: . .: .: :
CCDS91 ILQS-TNMAFGK-VTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLA
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 ATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLSQN
......: : . .. .. . . :.:... :. :..:..:: :: :
CCDS91 LHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLI
280 290 300 310 320 330
pF1KB6 C
CCDS91 VAEA
340
>>CCDS41843.2 RFC5 gene_id:5985|Hs108|chr12 (319 aa)
initn: 682 init1: 388 opt: 706 Z-score: 790.5 bits: 154.7 E(32554): 1e-37
Smith-Waterman score: 706; 39.5% identity (70.7% similar) in 314 aa overlap (41-353:2-306)
20 30 40 50 60 70
pF1KB6 STKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGAD
::::::. .... .........: ..
CCDS41 MVEKYRPQTLNDLISHQDILSTIQKFINEDR
10 20 30
80 90 100 110 120 130
pF1KB6 LPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLT
::.::.:::::::::::::: :..:. . : ::::::::.:::...: . .::
CCDS41 LPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFA---
40 50 60 70 80
140 150 160 170 180 190
pF1KB6 VSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPL
..:. : ::.:::::::.::. :: ::::..:: ...:::::::::.:.:: :
CCDS41 --STRTIFKK--GFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPAL
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB6 TSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATR
:::..::: ::. ... :: ....:.: ::..:. :: .: ::.:.:...::: :
CCDS41 QSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQS-TN
150 160 170 180 190 200
260 270 280 290 300
pF1KB6 LTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLID-EGHAATQLVNQ
.. :: .::... .: : ... . .: . .: .: : .....
CCDS41 MAFGK-VTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTE
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB6 LHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLSQNC
.: : . .. .. . . :.:... :. :..:..:: :: :
CCDS41 IHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA
270 280 290 300 310
>>CCDS5568.1 RFC2 gene_id:5982|Hs108|chr7 (354 aa)
initn: 639 init1: 347 opt: 673 Z-score: 753.2 bits: 147.9 E(32554): 1.2e-35
Smith-Waterman score: 676; 37.1% identity (67.1% similar) in 334 aa overlap (27-358:29-347)
10 20 30 40 50
pF1KB6 MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEV
::.:. . .:::::::: ..:.. .:..
CCDS55 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYE----LPWVEKYRPVKLNEIVGNEDT
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 VAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQV
:. :. . ...::... ::::::::..:: :: :.:: : . .::::::..:::.:
CCDS55 VSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPAL-KDAMLELNASNDRGIDV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 VREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCL
::.:.: ::: :. . :. ::.:::::::::..:: ::::::: :::::: :
CCDS55 VRNKIKMFAQQKVTLPK--GR----HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFAL
120 130 140 150 160
180 190 200 210 220 230
pF1KB6 ICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDL
:: ..::::. :::. .:. :.: ::... .:: : .:.:. .. ...::.
CCDS55 ACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDM
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 RKAITFLQSATRLTG--GKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDL
:.:.. :::. : ..: . :: . .. : :. : ....:. .. :
CCDS55 RQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQH----CVNANIDEAYKILAHL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB6 IDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVM
:.. ...... : .... : . .... . .:.:.. ::. .: : .
CCDS55 WHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLC
290 300 310 320 330 340
360
pF1KB6 QQLSQNC
:.
CCDS55 QKTMAPVAS
350
>>CCDS75618.1 RFC2 gene_id:5982|Hs108|chr7 (251 aa)
initn: 408 init1: 347 opt: 443 Z-score: 500.2 bits: 100.6 E(32554): 1.5e-21
Smith-Waterman score: 443; 33.1% identity (62.9% similar) in 248 aa overlap (111-358:5-244)
90 100 110 120 130 140
pF1KB6 GTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKP
:. :::.:::.:.: ::: :. :
CCDS75 MCPTSSLRGIDVVRNKIKMFAQQKVT------LP
10 20
150 160 170 180 190 200
pF1KB6 CPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFK
::.:::::::::..:: ::::::: :::::: : :: ..::::. :::. .:.
CCDS75 KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYT
30 40 50 60 70 80
210 220 230 240 250 260
pF1KB6 PLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEK
:.: ::... .:: : .:.:. .. ...::.:.:.. :::. ..: :. .
CCDS75 KLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQST--FSGFGFINSE
90 100 110 120 130 140
270 280 290 300 310 320
pF1KB6 VITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLS
. . . .. : ....:. .. : :.. ...... : ...
CCDS75 NVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMA
150 160 170 180 190 200
330 340 350 360
pF1KB6 DKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLSQNC
. : . .... . .:.:.. ::. .: : . :.
CCDS75 EYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
210 220 230 240 250
>>CCDS5567.1 RFC2 gene_id:5982|Hs108|chr7 (320 aa)
initn: 498 init1: 303 opt: 349 Z-score: 394.3 bits: 81.4 E(32554): 1.2e-15
Smith-Waterman score: 489; 31.1% identity (58.7% similar) in 334 aa overlap (27-358:29-313)
10 20 30 40 50
pF1KB6 MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEV
::.:. . .:::::::: ..:.. .:..
CCDS55 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYE----LPWVEKYRPVKLNEIVGNEDT
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 VAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQV
:. :. . ...::... ::::::::..:: :: :.:: : . .::::::.
CCDS55 VSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPAL-KDAMLELNASN------
60 70 80 90 100
120 130 140 150 160 170
pF1KB6 VREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCL
::::..:: ::::::: :::::: :
CCDS55 ----------------------------------DSMTDGAQQALRRTMEIYSKTTRFAL
110 120 130
180 190 200 210 220 230
pF1KB6 ICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDL
:: ..::::. :::. .:. :.: ::... .:: : .:.:. .. ...::.
CCDS55 ACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDM
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB6 RKAITFLQSATRLTG--GKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDL
:.:.. :::. : ..: . :: . .. : :. : ....:. .. :
CCDS55 RQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQH----CVNANIDEAYKILAHL
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB6 IDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVM
:.. ...... : .... : . .... . .:.:.. ::. .: : .
CCDS55 WHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLC
260 270 280 290 300 310
360
pF1KB6 QQLSQNC
:.
CCDS55 QKTMAPVAS
320
363 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:13:03 2016 done: Sat Nov 5 04:13:03 2016
Total Scan time: 2.330 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]