Result of FASTA (omim) for
pF1KB6517
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6517, 362 aa
1>>>pF1KB6517 362 - 362 aa - 362 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0194+/-0.000446; mu= 15.0603+/- 0.027
mean_var=154.6609+/-29.782, 0's: 0 Z-trim(115.5): 83 B-trim: 101 in 1/53
Lambda= 0.103130
statistics sampled from 25985 (26068) to 25985 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.306), width: 16
Scan time: 6.020
The best scores are: opt bits E(85289)
XP_011538068 (OMIM: 134637,601859) PREDICTED: tumo ( 362) 2475 380.3 3.8e-105
XP_006717882 (OMIM: 134637,601859) PREDICTED: tumo ( 362) 2475 380.3 3.8e-105
XP_011538066 (OMIM: 134637,601859) PREDICTED: tumo ( 389) 2475 380.3 3.9e-105
XP_011538069 (OMIM: 134637,601859) PREDICTED: tumo ( 350) 2238 345.0 1.5e-94
NP_000034 (OMIM: 134637,601859) tumor necrosis fac ( 335) 2224 342.9 6.3e-94
NP_690611 (OMIM: 134637,601859) tumor necrosis fac ( 220) 1492 233.7 2.9e-61
XP_011538067 (OMIM: 134637,601859) PREDICTED: tumo ( 368) 1408 221.5 2.3e-57
NP_001307548 (OMIM: 134637,601859) tumor necrosis ( 197) 1299 205.0 1.2e-52
NP_690610 (OMIM: 134637,601859) tumor necrosis fac ( 314) 1157 184.1 3.7e-46
NP_003835 (OMIM: 603611) tumor necrosis factor rec ( 468) 256 50.3 1.1e-05
XP_006719046 (OMIM: 600979) PREDICTED: tumor necro ( 255) 251 49.2 1.2e-05
XP_005253745 (OMIM: 600979) PREDICTED: tumor necro ( 399) 251 49.4 1.6e-05
NP_001257916 (OMIM: 600979) tumor necrosis factor ( 416) 251 49.4 1.7e-05
NP_002333 (OMIM: 600979) tumor necrosis factor rec ( 435) 251 49.5 1.7e-05
NP_001284534 (OMIM: 602746) tumor necrosis factor ( 184) 239 47.2 3.5e-05
XP_006711082 (OMIM: 602746) PREDICTED: tumor necro ( 197) 239 47.3 3.6e-05
NP_003833 (OMIM: 275355,603612) tumor necrosis fac ( 440) 243 48.3 4e-05
NP_001034753 (OMIM: 603366) tumor necrosis factor ( 181) 237 46.9 4.2e-05
NP_003811 (OMIM: 602746) tumor necrosis factor rec ( 283) 239 47.5 4.5e-05
NP_001233 (OMIM: 186711,615122) CD27 antigen precu ( 260) 236 47.0 5.9e-05
NP_690593 (OMIM: 109535,606843) tumor necrosis fac ( 203) 234 46.5 6.2e-05
NP_671716 (OMIM: 275355,603612) tumor necrosis fac ( 411) 238 47.5 6.4e-05
XP_016883626 (OMIM: 109535,606843) PREDICTED: tumo ( 222) 234 46.6 6.5e-05
NP_683867 (OMIM: 603366) tumor necrosis factor rec ( 380) 237 47.3 6.7e-05
NP_001289682 (OMIM: 109535,606843) tumor necrosis ( 237) 234 46.6 6.8e-05
NP_003781 (OMIM: 603366) tumor necrosis factor rec ( 417) 237 47.4 7.1e-05
XP_016875723 (OMIM: 186711,615122) PREDICTED: CD27 ( 358) 236 47.1 7.2e-05
NP_683866 (OMIM: 603366) tumor necrosis factor rec ( 426) 237 47.4 7.2e-05
NP_001241 (OMIM: 109535,606843) tumor necrosis fac ( 277) 234 46.7 7.5e-05
NP_001309350 (OMIM: 109535,606843) tumor necrosis ( 281) 234 46.7 7.6e-05
XP_016883625 (OMIM: 109535,606843) PREDICTED: tumo ( 289) 234 46.7 7.7e-05
XP_016875721 (OMIM: 186711,615122) PREDICTED: CD27 ( 405) 236 47.2 7.7e-05
XP_016883624 (OMIM: 109535,606843) PREDICTED: tumo ( 323) 234 46.8 8.3e-05
NP_002537 (OMIM: 239000,602643) tumor necrosis fac ( 401) 235 47.0 8.5e-05
XP_011527411 (OMIM: 109535,606843) PREDICTED: tumo ( 166) 225 45.1 0.00014
NP_003832 (OMIM: 603613) tumor necrosis factor rec ( 259) 224 45.2 0.0002
NP_001309351 (OMIM: 109535,606843) tumor necrosis ( 225) 223 44.9 0.00021
XP_005260676 (OMIM: 109535,606843) PREDICTED: tumo ( 229) 223 45.0 0.00021
NP_003831 (OMIM: 603614) tumor necrosis factor rec ( 386) 226 45.7 0.00021
XP_016869433 (OMIM: 275355,603612) PREDICTED: tumo ( 375) 224 45.4 0.00025
NP_001057 (OMIM: 191191) tumor necrosis factor rec ( 461) 212 43.7 0.001
XP_011540365 (OMIM: 191191) PREDICTED: tumor necro ( 462) 212 43.7 0.001
XP_011540362 (OMIM: 191191) PREDICTED: tumor necro ( 484) 212 43.7 0.001
XP_016857700 (OMIM: 191191) PREDICTED: tumor necro ( 491) 212 43.7 0.001
NP_003814 (OMIM: 603361) tumor necrosis factor rec ( 300) 209 43.0 0.001
NP_001257878 (OMIM: 174810,602080,603499,612301) t ( 263) 203 42.1 0.0018
NP_001257880 (OMIM: 174810,602080,603499,612301) t ( 299) 203 42.1 0.0019
NP_001257879 (OMIM: 174810,602080,603499,612301) t ( 337) 203 42.2 0.0021
XP_016857701 (OMIM: 191191) PREDICTED: tumor necro ( 440) 204 42.5 0.0022
XP_016857702 (OMIM: 191191) PREDICTED: tumor necro ( 440) 204 42.5 0.0022
>>XP_011538068 (OMIM: 134637,601859) PREDICTED: tumor ne (362 aa)
initn: 2475 init1: 2475 opt: 2475 Z-score: 2008.8 bits: 380.3 E(85289): 3.8e-105
Smith-Waterman score: 2475; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362)
10 20 30 40 50 60
pF1KB6 MLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARLSSKSVNAQVTDINSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARLSSKSVNAQVTDINSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 IKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 KVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQS
310 320 330 340 350 360
pF1KB6 LV
::
XP_011 LV
>>XP_006717882 (OMIM: 134637,601859) PREDICTED: tumor ne (362 aa)
initn: 2475 init1: 2475 opt: 2475 Z-score: 2008.8 bits: 380.3 E(85289): 3.8e-105
Smith-Waterman score: 2475; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362)
10 20 30 40 50 60
pF1KB6 MLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARLSSKSVNAQVTDINSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARLSSKSVNAQVTDINSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 IKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 KVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQS
310 320 330 340 350 360
pF1KB6 LV
::
XP_006 LV
>>XP_011538066 (OMIM: 134637,601859) PREDICTED: tumor ne (389 aa)
initn: 2475 init1: 2475 opt: 2475 Z-score: 2008.4 bits: 380.3 E(85289): 3.9e-105
Smith-Waterman score: 2475; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:28-389)
10 20 30
pF1KB6 MLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTP
:::::::::::::::::::::::::::::::::
XP_011 MSGFPEQRLLLLHVSFPERGINITWELMLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTP
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 TRLVVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRLVVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 ERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 CRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 IVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVK
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 GFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTL
310 320 330 340 350 360
340 350 360
pF1KB6 AEKIQTIILKDITSDSENSNFRNEIQSLV
:::::::::::::::::::::::::::::
XP_011 AEKIQTIILKDITSDSENSNFRNEIQSLV
370 380
>>XP_011538069 (OMIM: 134637,601859) PREDICTED: tumor ne (350 aa)
initn: 2230 init1: 2230 opt: 2238 Z-score: 1818.4 bits: 345.0 E(85289): 1.5e-94
Smith-Waterman score: 2238; 95.1% identity (96.8% similar) in 348 aa overlap (15-362:6-350)
10 20 30 40 50 60
pF1KB6 MLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARLSSKSVNAQVTDINSK
: : . :. ..:: : .. :::::::::::::::::::::::
XP_011 MRSADPAGQAGQLRRSSET---TALHVEVLTSVARLSSKSVNAQVTDINSK
10 20 30 40
70 80 90 100 110 120
pF1KB6 GLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 KAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 IKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 TLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 KVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQS
290 300 310 320 330 340
pF1KB6 LV
::
XP_011 LV
350
>>NP_000034 (OMIM: 134637,601859) tumor necrosis factor (335 aa)
initn: 2224 init1: 2224 opt: 2224 Z-score: 1807.3 bits: 342.9 E(85289): 6.3e-94
Smith-Waterman score: 2224; 99.7% identity (100.0% similar) in 326 aa overlap (37-362:10-335)
10 20 30 40 50 60
pF1KB6 QGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARLSSKSVNAQVTDINSKGLELRK
.:::::::::::::::::::::::::::::
NP_000 MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRK
10 20 30
70 80 90 100 110 120
pF1KB6 TVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 KCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 TSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPET
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 VAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLR
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 NWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV
280 290 300 310 320 330
>>NP_690611 (OMIM: 134637,601859) tumor necrosis factor (220 aa)
initn: 1492 init1: 1492 opt: 1492 Z-score: 1220.7 bits: 233.7 E(85289): 2.9e-61
Smith-Waterman score: 1492; 99.5% identity (100.0% similar) in 208 aa overlap (37-244:10-217)
10 20 30 40 50 60
pF1KB6 QGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARLSSKSVNAQVTDINSKGLELRK
.:::::::::::::::::::::::::::::
NP_690 MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRK
10 20 30
70 80 90 100 110 120
pF1KB6 TVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 TVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 KCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 TSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 TSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPML
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 VAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLR
NP_690 T
220
>>XP_011538067 (OMIM: 134637,601859) PREDICTED: tumor ne (368 aa)
initn: 1408 init1: 1408 opt: 1408 Z-score: 1150.7 bits: 221.5 E(85289): 2.3e-57
Smith-Waterman score: 2270; 94.2% identity (94.2% similar) in 362 aa overlap (1-362:28-368)
10 20 30
pF1KB6 MLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTP
:::::::::::::::::::::::::::::::::
XP_011 MSGFPEQRLLLLHVSFPERGINITWELMLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTP
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 TRLVVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRLVVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 ERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 CRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPL
::::::::::::::::::::::::::::::::::::::::::
XP_011 CRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEE------------------
190 200 210 220
220 230 240 250 260 270
pF1KB6 IVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ---VKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVK
230 240 250 260 270
280 290 300 310 320 330
pF1KB6 GFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTL
280 290 300 310 320 330
340 350 360
pF1KB6 AEKIQTIILKDITSDSENSNFRNEIQSLV
:::::::::::::::::::::::::::::
XP_011 AEKIQTIILKDITSDSENSNFRNEIQSLV
340 350 360
>>NP_001307548 (OMIM: 134637,601859) tumor necrosis fact (197 aa)
initn: 1299 init1: 1299 opt: 1299 Z-score: 1066.1 bits: 205.0 E(85289): 1.2e-52
Smith-Waterman score: 1299; 99.4% identity (100.0% similar) in 180 aa overlap (37-216:10-189)
10 20 30 40 50 60
pF1KB6 QGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARLSSKSVNAQVTDINSKGLELRK
.:::::::::::::::::::::::::::::
NP_001 MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRK
10 20 30
70 80 90 100 110 120
pF1KB6 TVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 KCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 TSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPET
::::::::::::::::::::::::::::::
NP_001 TSNTKCKEEGSRSNLGWLCLLLLPIPLIVWGNSGNKFI
160 170 180 190
>>NP_690610 (OMIM: 134637,601859) tumor necrosis factor (314 aa)
initn: 1157 init1: 1157 opt: 1157 Z-score: 949.6 bits: 184.1 E(85289): 3.7e-46
Smith-Waterman score: 2019; 93.3% identity (93.6% similar) in 326 aa overlap (37-362:10-314)
10 20 30 40 50 60
pF1KB6 QGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARLSSKSVNAQVTDINSKGLELRK
.:::::::::::::::::::::::::::::
NP_690 MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRK
10 20 30
70 80 90 100 110 120
pF1KB6 TVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 TVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 KCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 TSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPET
::::::::: ::::::::::::::::::::::::::::::
NP_690 TSNTKCKEE---------------------VKRKEVQKTCRKHRKENQGSHESPTLNPET
160 170 180 190
250 260 270 280 290 300
pF1KB6 VAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 VAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLR
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB6 NWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 NWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV
260 270 280 290 300 310
>>NP_003835 (OMIM: 603611) tumor necrosis factor recepto (468 aa)
initn: 232 init1: 116 opt: 256 Z-score: 223.2 bits: 50.3 E(85289): 1.1e-05
Smith-Waterman score: 256; 33.6% identity (56.6% similar) in 143 aa overlap (84-215:122-254)
60 70 80 90 100
pF1KB6 VTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKP----CPPGERKARDCTVNGDEPD-
:. :.: :::: ... ..:
NP_003 FKFVVVGVLLQVVPSSAATIKLHDQSIGTQQWEHSPLGELCPPGSHRS-------EHPGA
100 110 120 130 140
110 120 130 140 150 160
pF1KB6 CVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCE
: : :: ::. .. : : : . : . :: :.:: :.:::. : :.. :
NP_003 CNRCTEGVGYTNASNNLFACLPCTACKSDE--EERSPCTTTRNTACQCKPGTFRNDNSAE
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB6 HCDPCTK-CEHGIIK--ECTLTSNTKC--KEEGSRSNLGWLCLLL-LPIPLIVWVKRKEV
: :.. : .:..: .:: :. .: :: :. :. :. :.. : .::..
NP_003 MCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNI-WVILVVTLVVPLLLVAVLIVC
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB6 QKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVN
NP_003 CCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQEPA
270 280 290 300 310 320
362 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:12:45 2016 done: Fri Nov 4 23:12:47 2016
Total Scan time: 6.020 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]