FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6494, 270 aa
  1>>>pF1KB6494 270 - 270 aa - 270 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6852+/-0.000307; mu= 14.3004+/- 0.019
 mean_var=79.6107+/-16.179, 0's: 0 Z-trim(116.9): 12  B-trim: 0 in 0/55
 Lambda= 0.143744
 statistics sampled from 28388 (28399) to 28388 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.333), width:  16
 Scan time:  6.630

The best scores are:                                      opt bits E(85289)
NP_002937 (OMIM: 179836) replication protein A 32  ( 270) 1776 377.3 1.6e-104
NP_001284487 (OMIM: 179836) replication protein A  ( 278) 1742 370.3 2.2e-102
NP_001273005 (OMIM: 179836) replication protein A  ( 174) 1145 246.3 2.8e-65
NP_037479 (OMIM: 300767) replication protein A 30  ( 261)  708 155.8 7.4e-38


>>NP_002937 (OMIM: 179836) replication protein A 32 kDa   (270 aa)
 initn: 1776 init1: 1776 opt: 1776  Z-score: 1997.4  bits: 377.3 E(85289): 1.6e-104
Smith-Waterman score: 1776; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)

               10        20        30        40        50        60
pF1KB6 MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 DEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 PPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 APISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 APISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVS
              190       200       210       220       230       240

              250       260       270
pF1KB6 SIKQAVDFLSNEGHIYSTVDDDHFKSTDAE
       ::::::::::::::::::::::::::::::
NP_002 SIKQAVDFLSNEGHIYSTVDDDHFKSTDAE
              250       260       270

>>NP_001284487 (OMIM: 179836) replication protein A 32 k  (278 aa)
 initn: 1742 init1: 1742 opt: 1742  Z-score: 1959.1  bits: 370.3 E(85289): 2.2e-102
Smith-Waterman score: 1742; 100.0% identity (100.0% similar) in 266 aa overlap (5-270:13-278)

                       10        20        30        40        50  
pF1KB6         MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTIS
                   ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRGDRNKRSIRGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTIS
               10        20        30        40        50        60

             60        70        80        90       100       110  
pF1KB6 QLLSATLVDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLSATLVDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDD
               70        80        90       100       110       120

            120       130       140       150       160       170  
pF1KB6 TSSENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSSENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKA
              130       140       150       160       170       180

            180       190       200       210       220       230  
pF1KB6 NSQPSAGRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSQPSAGRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKN
              190       200       210       220       230       240

            240       250       260       270
pF1KB6 QLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKSTDAE
       ::::::::::::::::::::::::::::::::::::::
NP_001 QLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKSTDAE
              250       260       270        

>>NP_001273005 (OMIM: 179836) replication protein A 32 k  (174 aa)
 initn: 1145 init1: 1145 opt: 1145  Z-score: 1292.9  bits: 246.3 E(85289): 2.8e-65
Smith-Waterman score: 1145; 100.0% identity (100.0% similar) in 174 aa overlap (97-270:1-174)

         70        80        90       100       110       120      
pF1KB6 GNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVVPPETYV
                                     ::::::::::::::::::::::::::::::
NP_001                               MTAAPMDVRQWVDTDDTSSENTVVPPETYV
                                             10        20        30

        130       140       150       160       170       180      
pF1KB6 KVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGRAPISNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGRAPISNP
               40        50        60        70        80        90

        190       200       210       220       230       240      
pF1KB6 GMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAV
              100       110       120       130       140       150

        250       260       270
pF1KB6 DFLSNEGHIYSTVDDDHFKSTDAE
       ::::::::::::::::::::::::
NP_001 DFLSNEGHIYSTVDDDHFKSTDAE
              160       170    

>>NP_037479 (OMIM: 300767) replication protein A 30 kDa   (261 aa)
 initn: 702 init1: 315 opt: 708  Z-score: 800.6  bits: 155.8 E(85289): 7.4e-38
Smith-Waterman score: 708; 45.9% identity (72.2% similar) in 270 aa overlap (1-268:1-261)

               10          20        30        40        50        
pF1KB6 MWNSGFESYGSSSY--GGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSAT
       : .::: :::: :   :..::  :     ..:: .   .. ..: : .:::...::::.:
NP_037 MSKSGFGSYGSISAADGASGGSDQLCERDATPAIK--TQRPKVRIQDVVPCNVNQLLSST
               10        20        30          40        50        

       60        70        80        90       100       110        
pF1KB6 LVDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENT
       . : ::.. .. .:::.:::.:: :::: ..: :::::::: :...:::   . .. . :
NP_037 VFDPVFKVRGIIVSQVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKVK-QVT
       60        70        80        90       100       110        

      120       130       140       150       160       170        
pF1KB6 VVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSA
        .   .:::: : :.   . ::: ..::  ::::::::.::::..::::.:.::  . ..
NP_037 PLSVGVYVKVFGILKCPTGTKSLEVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTV
       120       130       140       150       160       170       

      180       190       200       210       220       230        
pF1KB6 GRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMS
         .:.: :  ::... : :.    : .   :..:: ::. ::. :: ....:. ::  .:
NP_037 ESVPVS-P--SEVNDAGDNDESHRNFI---QDEVLRLIHECPHQEGKSIHELRAQLCDLS
       180          190       200          210       220       230 

      240       250       260       270
pF1KB6 VSSIKQAVDFLSNEGHIYSTVDDDHFKSTDAE
       :..::.:.:.:. ::::: ::: .::::.:  
NP_037 VKAIKEAIDYLTVEGHIYPTVDREHFKSAD  
             240       250       260   




270 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:34:56 2016 done: Sat Nov  5 07:34:57 2016
 Total Scan time:  6.630 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]