Result of FASTA (omim) for
pF1KB6402
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6402, 333 aa
1>>>pF1KB6402 333 - 333 aa - 333 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4930+/-0.000399; mu= 14.6756+/- 0.025
mean_var=67.1104+/-13.494, 0's: 0 Z-trim(111.9): 59 B-trim: 44 in 1/49
Lambda= 0.156559
statistics sampled from 20570 (20630) to 20570 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.242), width: 16
Scan time: 7.220
The best scores are: opt bits E(85289)
NP_001903 (OMIM: 116880) cathepsin L1 isoform 1 pr ( 333) 2321 533.4 2.6e-151
XP_005251773 (OMIM: 116880) PREDICTED: cathepsin L ( 333) 2321 533.4 2.6e-151
NP_001244900 (OMIM: 116880) cathepsin L1 isoform 1 ( 333) 2321 533.4 2.6e-151
NP_666023 (OMIM: 116880) cathepsin L1 isoform 1 pr ( 333) 2321 533.4 2.6e-151
NP_001244901 (OMIM: 116880) cathepsin L1 isoform 1 ( 333) 2321 533.4 2.6e-151
NP_001324 (OMIM: 603308) cathepsin L2 preproprotei ( 334) 1836 423.8 2.5e-118
NP_001188504 (OMIM: 603308) cathepsin L2 prepropro ( 334) 1836 423.8 2.5e-118
XP_016869782 (OMIM: 116880) PREDICTED: cathepsin L ( 272) 1804 416.5 3.1e-116
XP_011516565 (OMIM: 116880) PREDICTED: cathepsin L ( 272) 1804 416.5 3.1e-116
NP_000387 (OMIM: 265800,601105) cathepsin K prepro ( 329) 1131 264.6 2.1e-70
NP_004070 (OMIM: 116845) cathepsin S isoform 1 pre ( 331) 1101 257.8 2.3e-68
NP_001244902 (OMIM: 116880) cathepsin L1 isoform 2 ( 151) 1041 244.1 1.4e-64
NP_001186668 (OMIM: 116845) cathepsin S isoform 2 ( 281) 796 188.9 1.1e-47
NP_004381 (OMIM: 116820) pro-cathepsin H isoform a ( 335) 796 188.9 1.3e-47
XP_016877440 (OMIM: 116820) PREDICTED: pro-catheps ( 317) 770 183.0 7.2e-46
XP_016877441 (OMIM: 116820) PREDICTED: pro-catheps ( 297) 767 182.3 1.1e-45
XP_005254238 (OMIM: 116820) PREDICTED: pro-catheps ( 297) 767 182.3 1.1e-45
XP_011543630 (OMIM: 603539,615362) PREDICTED: cath ( 424) 664 159.1 1.5e-38
NP_003784 (OMIM: 603539,615362) cathepsin F precur ( 484) 664 159.2 1.7e-38
NP_001325 (OMIM: 600550) cathepsin O preproprotein ( 321) 484 118.4 2e-26
NP_001306066 (OMIM: 116820) pro-cathepsin H isofor ( 201) 459 112.7 6.8e-25
NP_001326 (OMIM: 602364) cathepsin W preproprotein ( 376) 403 100.2 7.5e-21
NP_001805 (OMIM: 170650,245000,245010,602365) dipe ( 463) 386 96.4 1.3e-19
XP_011519578 (OMIM: 116820) PREDICTED: pro-catheps ( 169) 338 85.3 9.9e-17
NP_001327 (OMIM: 603169) cathepsin Z preproprotein ( 303) 305 78.0 2.9e-14
NP_001304166 (OMIM: 116810) cathepsin B isoform 2 ( 215) 223 59.4 8e-09
XP_016868590 (OMIM: 116810) PREDICTED: cathepsin B ( 245) 223 59.4 9e-09
XP_006716307 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 223 59.5 1.2e-08
XP_016868586 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 223 59.5 1.2e-08
NP_680092 (OMIM: 116810) cathepsin B isoform 1 pre ( 339) 223 59.5 1.2e-08
XP_006716308 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 223 59.5 1.2e-08
NP_001899 (OMIM: 116810) cathepsin B isoform 1 pre ( 339) 223 59.5 1.2e-08
XP_016868588 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 223 59.5 1.2e-08
NP_680091 (OMIM: 116810) cathepsin B isoform 1 pre ( 339) 223 59.5 1.2e-08
XP_016868589 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 223 59.5 1.2e-08
NP_680093 (OMIM: 116810) cathepsin B isoform 1 pre ( 339) 223 59.5 1.2e-08
XP_011542114 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 223 59.5 1.2e-08
NP_680090 (OMIM: 116810) cathepsin B isoform 1 pre ( 339) 223 59.5 1.2e-08
XP_016868587 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 223 59.5 1.2e-08
XP_005271164 (OMIM: 616064) PREDICTED: tubulointer ( 362) 196 53.4 8.6e-07
NP_001191344 (OMIM: 616064) tubulointerstitial nep ( 362) 196 53.4 8.6e-07
XP_011540248 (OMIM: 616064) PREDICTED: tubulointer ( 408) 196 53.4 9.6e-07
NP_001191343 (OMIM: 616064) tubulointerstitial nep ( 436) 196 53.4 1e-06
NP_071447 (OMIM: 616064) tubulointerstitial nephri ( 467) 196 53.5 1.1e-06
XP_016866237 (OMIM: 606749) PREDICTED: tubulointer ( 309) 178 49.3 1.3e-05
XP_016866236 (OMIM: 606749) PREDICTED: tubulointer ( 351) 178 49.3 1.4e-05
XP_016866235 (OMIM: 606749) PREDICTED: tubulointer ( 401) 178 49.4 1.6e-05
XP_011512799 (OMIM: 606749) PREDICTED: tubulointer ( 426) 178 49.4 1.7e-05
XP_006715125 (OMIM: 606749) PREDICTED: tubulointer ( 458) 178 49.4 1.8e-05
NP_055279 (OMIM: 606749) tubulointerstitial nephri ( 476) 178 49.4 1.8e-05
>>NP_001903 (OMIM: 116880) cathepsin L1 isoform 1 prepro (333 aa)
initn: 2321 init1: 2321 opt: 2321 Z-score: 2837.4 bits: 533.4 E(85289): 2.6e-151
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333)
10 20 30 40 50 60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
250 260 270 280 290 300
310 320 330
pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
:::::::::::::::::::::::::::::::::
NP_001 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
310 320 330
>>XP_005251773 (OMIM: 116880) PREDICTED: cathepsin L1 is (333 aa)
initn: 2321 init1: 2321 opt: 2321 Z-score: 2837.4 bits: 533.4 E(85289): 2.6e-151
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333)
10 20 30 40 50 60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
250 260 270 280 290 300
310 320 330
pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
:::::::::::::::::::::::::::::::::
XP_005 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
310 320 330
>>NP_001244900 (OMIM: 116880) cathepsin L1 isoform 1 pre (333 aa)
initn: 2321 init1: 2321 opt: 2321 Z-score: 2837.4 bits: 533.4 E(85289): 2.6e-151
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333)
10 20 30 40 50 60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
250 260 270 280 290 300
310 320 330
pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
:::::::::::::::::::::::::::::::::
NP_001 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
310 320 330
>>NP_666023 (OMIM: 116880) cathepsin L1 isoform 1 prepro (333 aa)
initn: 2321 init1: 2321 opt: 2321 Z-score: 2837.4 bits: 533.4 E(85289): 2.6e-151
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333)
10 20 30 40 50 60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_666 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_666 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_666 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_666 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_666 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
250 260 270 280 290 300
310 320 330
pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
:::::::::::::::::::::::::::::::::
NP_666 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
310 320 330
>>NP_001244901 (OMIM: 116880) cathepsin L1 isoform 1 pre (333 aa)
initn: 2321 init1: 2321 opt: 2321 Z-score: 2837.4 bits: 533.4 E(85289): 2.6e-151
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333)
10 20 30 40 50 60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
250 260 270 280 290 300
310 320 330
pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
:::::::::::::::::::::::::::::::::
NP_001 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
310 320 330
>>NP_001324 (OMIM: 603308) cathepsin L2 preproprotein [H (334 aa)
initn: 1824 init1: 1251 opt: 1836 Z-score: 2245.4 bits: 423.8 E(85289): 2.5e-118
Smith-Waterman score: 1836; 77.2% identity (91.0% similar) in 334 aa overlap (1-333:1-334)
10 20 30 40 50 60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
:: .:.:::::::::::. ::..:...: .::: : :::: ::::::::::::::::::
NP_001 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
::: :: .:::.::::::::::::.:::::.:. :.:.: ::::::.:::: . :.::::
NP_001 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
:.:::::::::: :::::::::::::::::::::::.:.::::::::::: ::::.::::
NP_001 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQEKALMKAV
:.: :::::..:::::::::::: :..: ::: :. ::::::::. . : .::::::::
NP_001 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK
:::::::::.:::: :: ::: ::::::::::...::::::::::::...:.:.::::::
NP_001 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
250 260 270 280 290 300
300 310 320 330
pF1KB6 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
:::: ::: .::::.:::. ::::::.:::::.:
NP_001 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
310 320 330
>>NP_001188504 (OMIM: 603308) cathepsin L2 preproprotein (334 aa)
initn: 1824 init1: 1251 opt: 1836 Z-score: 2245.4 bits: 423.8 E(85289): 2.5e-118
Smith-Waterman score: 1836; 77.2% identity (91.0% similar) in 334 aa overlap (1-333:1-334)
10 20 30 40 50 60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
:: .:.:::::::::::. ::..:...: .::: : :::: ::::::::::::::::::
NP_001 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
::: :: .:::.::::::::::::.:::::.:. :.:.: ::::::.:::: . :.::::
NP_001 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
:.:::::::::: :::::::::::::::::::::::.:.::::::::::: ::::.::::
NP_001 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQEKALMKAV
:.: :::::..:::::::::::: :..: ::: :. ::::::::. . : .::::::::
NP_001 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK
:::::::::.:::: :: ::: ::::::::::...::::::::::::...:.:.::::::
NP_001 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
250 260 270 280 290 300
300 310 320 330
pF1KB6 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
:::: ::: .::::.:::. ::::::.:::::.:
NP_001 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
310 320 330
>>XP_016869782 (OMIM: 116880) PREDICTED: cathepsin L1 is (272 aa)
initn: 1804 init1: 1804 opt: 1804 Z-score: 2207.7 bits: 416.5 E(85289): 3.1e-116
Smith-Waterman score: 1804; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)
10 20 30 40 50 60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
:::::::::::::::::::::
XP_016 TVGPISVAIDAGHESFLFYKEAGVKNGAWVAT
250 260 270
>>XP_011516565 (OMIM: 116880) PREDICTED: cathepsin L1 is (272 aa)
initn: 1804 init1: 1804 opt: 1804 Z-score: 2207.7 bits: 416.5 E(85289): 3.1e-116
Smith-Waterman score: 1804; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)
10 20 30 40 50 60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
:::::::::::::::::::::
XP_011 TVGPISVAIDAGHESFLFYKEAGVKNGAWVAT
250 260 270
>>NP_000387 (OMIM: 265800,601105) cathepsin K preproprot (329 aa)
initn: 887 init1: 321 opt: 1131 Z-score: 1384.9 bits: 264.6 E(85289): 2.1e-70
Smith-Waterman score: 1131; 50.9% identity (76.7% similar) in 330 aa overlap (7-331:4-327)
10 20 30 40 50
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMI
: .. : ..: .: .. :...: :: : . :. . .: :: .::::.:.:
NP_000 MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYI
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN--RKPRKGKVFQEPLFY-EAPR
.:: : : :.. .::: .::::::: : :.:.. . :.. .. : . .::
NP_000 SIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 SVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE
:::.:.::::::::::::::::::::..::::::. .:::.:..:: :::::: . :.
NP_000 SVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--ND
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKAL
::.:: : :::::: : :.:::..::: . :::: ::: ..:. :. .::. .::::
NP_000 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 MKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKY
.::: :::.::::::. :: ::..:.:.. .:.:....:.::.::::... .::.
NP_000 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK----GNKH
240 250 260 270 280 290
300 310 320 330
pF1KB6 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
:..::::::.:: ::. ::... : ::::. ::.:
NP_000 WIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
300 310 320
333 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:49:15 2016 done: Fri Nov 4 20:49:16 2016
Total Scan time: 7.220 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]