Result of FASTA (omim) for
pF1KB6355
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6355, 266 aa
1>>>pF1KB6355 266 - 266 aa - 266 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4290+/-0.000424; mu= 6.7910+/- 0.027
mean_var=215.6739+/-48.529, 0's: 0 Z-trim(116.7): 143 B-trim: 1727 in 1/55
Lambda= 0.087332
statistics sampled from 27891 (28083) to 27891 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.329), width: 16
Scan time: 7.290
The best scores are: opt bits E(85289)
NP_057174 (OMIM: 612413) RNA-binding protein 7 iso ( 266) 1820 241.8 1e-63
NP_001272974 (OMIM: 612413) RNA-binding protein 7 ( 267) 1808 240.3 2.9e-63
NP_001272977 (OMIM: 612413) RNA-binding protein 7 ( 146) 1030 141.9 6.2e-34
NP_001272976 (OMIM: 612413) RNA-binding protein 7 ( 146) 1030 141.9 6.2e-34
NP_001272975 (OMIM: 612413) RNA-binding protein 7 ( 146) 1030 141.9 6.2e-34
NP_005841 (OMIM: 154400,605593) splicing factor 3B ( 424) 255 44.8 0.00031
XP_011529739 (OMIM: 400006,415000) PREDICTED: RNA- ( 422) 242 43.2 0.00096
NP_001307873 (OMIM: 400006,415000) RNA-binding mot ( 459) 242 43.2 0.001
NP_005049 (OMIM: 400006,415000) RNA-binding motif ( 496) 242 43.3 0.0011
XP_011529740 (OMIM: 400006,415000) PREDICTED: RNA- ( 385) 235 42.3 0.0017
NP_002130 (OMIM: 300199,300238) RNA-binding motif ( 391) 216 39.9 0.0088
>>NP_057174 (OMIM: 612413) RNA-binding protein 7 isoform (266 aa)
initn: 1820 init1: 1820 opt: 1820 Z-score: 1265.1 bits: 241.8 E(85289): 1e-63
Smith-Waterman score: 1820; 100.0% identity (100.0% similar) in 266 aa overlap (1-266:1-266)
10 20 30 40 50 60
pF1KB6 MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPSRYERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPSRYERT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 MDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYGGKFGSSPLDQSGFSPSVQSHSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYGGKFGSSPLDQSGFSPSVQSHSHS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 FNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGKRDDFFYEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGKRDDFFYEDR
190 200 210 220 230 240
250 260
pF1KB6 NHDDWSHDYDNRRDSSRDGKWRSSRH
::::::::::::::::::::::::::
NP_057 NHDDWSHDYDNRRDSSRDGKWRSSRH
250 260
>>NP_001272974 (OMIM: 612413) RNA-binding protein 7 isof (267 aa)
initn: 1076 init1: 1076 opt: 1808 Z-score: 1256.9 bits: 240.3 E(85289): 2.9e-63
Smith-Waterman score: 1808; 99.6% identity (99.6% similar) in 267 aa overlap (1-266:1-267)
10 20 30 40 50 60
pF1KB6 MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHE
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 VSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPS-RYER
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 VSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPSSRYER
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 TMDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYGGKFGSSPLDQSGFSPSVQSHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYGGKFGSSPLDQSGFSPSVQSHSH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 SFNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGKRDDFFYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGKRDDFFYED
190 200 210 220 230 240
240 250 260
pF1KB6 RNHDDWSHDYDNRRDSSRDGKWRSSRH
:::::::::::::::::::::::::::
NP_001 RNHDDWSHDYDNRRDSSRDGKWRSSRH
250 260
>>NP_001272977 (OMIM: 612413) RNA-binding protein 7 isof (146 aa)
initn: 1030 init1: 1030 opt: 1030 Z-score: 730.2 bits: 141.9 E(85289): 6.2e-34
Smith-Waterman score: 1030; 100.0% identity (100.0% similar) in 146 aa overlap (121-266:1-146)
100 110 120 130 140 150
pF1KB6 APQDVSLSYPQHHVGNSSPTSTSPSRYERTMDNMTSSAQIIQRSFSSPENFQRQAVMNSA
::::::::::::::::::::::::::::::
NP_001 MDNMTSSAQIIQRSFSSPENFQRQAVMNSA
10 20 30
160 170 180 190 200 210
pF1KB6 LRQMSYGGKFGSSPLDQSGFSPSVQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRQMSYGGKFGSSPLDQSGFSPSVQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLAD
40 50 60 70 80 90
220 230 240 250 260
pF1KB6 RHYSREQRYTDHGSDHHYRGKRDDFFYEDRNHDDWSHDYDNRRDSSRDGKWRSSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHYSREQRYTDHGSDHHYRGKRDDFFYEDRNHDDWSHDYDNRRDSSRDGKWRSSRH
100 110 120 130 140
>>NP_001272976 (OMIM: 612413) RNA-binding protein 7 isof (146 aa)
initn: 1030 init1: 1030 opt: 1030 Z-score: 730.2 bits: 141.9 E(85289): 6.2e-34
Smith-Waterman score: 1030; 100.0% identity (100.0% similar) in 146 aa overlap (121-266:1-146)
100 110 120 130 140 150
pF1KB6 APQDVSLSYPQHHVGNSSPTSTSPSRYERTMDNMTSSAQIIQRSFSSPENFQRQAVMNSA
::::::::::::::::::::::::::::::
NP_001 MDNMTSSAQIIQRSFSSPENFQRQAVMNSA
10 20 30
160 170 180 190 200 210
pF1KB6 LRQMSYGGKFGSSPLDQSGFSPSVQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRQMSYGGKFGSSPLDQSGFSPSVQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLAD
40 50 60 70 80 90
220 230 240 250 260
pF1KB6 RHYSREQRYTDHGSDHHYRGKRDDFFYEDRNHDDWSHDYDNRRDSSRDGKWRSSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHYSREQRYTDHGSDHHYRGKRDDFFYEDRNHDDWSHDYDNRRDSSRDGKWRSSRH
100 110 120 130 140
>>NP_001272975 (OMIM: 612413) RNA-binding protein 7 isof (146 aa)
initn: 1030 init1: 1030 opt: 1030 Z-score: 730.2 bits: 141.9 E(85289): 6.2e-34
Smith-Waterman score: 1030; 100.0% identity (100.0% similar) in 146 aa overlap (121-266:1-146)
100 110 120 130 140 150
pF1KB6 APQDVSLSYPQHHVGNSSPTSTSPSRYERTMDNMTSSAQIIQRSFSSPENFQRQAVMNSA
::::::::::::::::::::::::::::::
NP_001 MDNMTSSAQIIQRSFSSPENFQRQAVMNSA
10 20 30
160 170 180 190 200 210
pF1KB6 LRQMSYGGKFGSSPLDQSGFSPSVQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRQMSYGGKFGSSPLDQSGFSPSVQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLAD
40 50 60 70 80 90
220 230 240 250 260
pF1KB6 RHYSREQRYTDHGSDHHYRGKRDDFFYEDRNHDDWSHDYDNRRDSSRDGKWRSSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHYSREQRYTDHGSDHHYRGKRDDFFYEDRNHDDWSHDYDNRRDSSRDGKWRSSRH
100 110 120 130 140
>>NP_005841 (OMIM: 154400,605593) splicing factor 3B sub (424 aa)
initn: 254 init1: 148 opt: 255 Z-score: 197.1 bits: 44.8 E(85289): 0.00031
Smith-Waterman score: 255; 41.7% identity (75.7% similar) in 103 aa overlap (9-109:12-109)
10 20 30 40 50
pF1KB6 MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDK-DGKPKQFAFVN
: :..::.:. ::.: ::.::: :::::.....:::. :. . ..::.
NP_005 MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 FKHEVSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQ-DVSLSYPQHHVGNSSPTSTSPS
: : .. ::....: :::::.::... ..:.: . ::. . .:: .:
NP_005 FLSEEDADYAIKIMNMIKLYGKPIRVN--KASAHNKNLDVGANI---FIGNLDPEIDEKL
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RYERTMDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYGGKFGSSPLDQSGFSPSVQ
NP_005 LYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS
120 130 140 150 160 170
>>XP_011529739 (OMIM: 400006,415000) PREDICTED: RNA-bind (422 aa)
initn: 192 init1: 170 opt: 242 Z-score: 188.2 bits: 43.2 E(85289): 0.00096
Smith-Waterman score: 242; 25.0% identity (57.5% similar) in 268 aa overlap (7-265:3-263)
10 20 30 40 50
pF1KB6 MGAAAAEADRT--LFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFK
:::. ::.:.:. ...:..: .: . ::. .: . ::. .: . :::..:.
XP_011 MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRGFAFITFE
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 HEVSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPT-STSPSRY
. ... : . .:: .:.:. ::.. .... . :. . : : ::. : .:
XP_011 NPADAKNAAKDMNGKSLHGKAIKVE--QAKKPSFQSGGRRRPPASSRNRSPSGSLRSARG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ER--TMDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYG--GKFGSSPLDQSGFSPS
: : . : .. . .:. . .. .: .. : .. :. : .:. :
XP_011 SRGGTRGWLPSHEGHLDDGGYTPD---LKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 VQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGKRD
..:.: .:. :: :.. :.. ..:. :: .:.. :. . ..: .
XP_011 ARSNSWMGSQGPMSQRRENYGVPPRRATISSWR--NDRMSTRHDGYATNDGNHPSCQETR
180 190 200 210 220
240 250 260
pF1KB6 DFFYEDRNHDDWSHDYDNRRDSSRDG--KWRSSRH
:. .:.. .. ..:: . : : . ::::
XP_011 DYAPPSRGYAYRDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESY
230 240 250 260 270 280
XP_011 SRGYRNRRSSRETREYAPPSRGHGYRDYGHSRRHESYSRGYRNHPSSRETRDYAPPHRDY
290 300 310 320 330 340
>>NP_001307873 (OMIM: 400006,415000) RNA-binding motif p (459 aa)
initn: 224 init1: 170 opt: 242 Z-score: 187.8 bits: 43.2 E(85289): 0.001
Smith-Waterman score: 242; 25.0% identity (57.5% similar) in 268 aa overlap (7-265:3-263)
10 20 30 40 50
pF1KB6 MGAAAAEADRT--LFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFK
:::. ::.:.:. ...:..: .: . ::. .: . ::. .: . :::..:.
NP_001 MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRGFAFITFE
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 HEVSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPT-STSPSRY
. ... : . .:: .:.:. ::.. .... . :. . : : ::. : .:
NP_001 NPADAKNAAKDMNGKSLHGKAIKVE--QAKKPSFQSGGRRRPPASSRNRSPSGSLRSARG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ER--TMDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYG--GKFGSSPLDQSGFSPS
: : . : .. . .:. . .. .: .. : .. :. : .:. :
NP_001 SRGGTRGWLPSHEGHLDDGGYTPD---LKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 VQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGKRD
..:.: .:. :: :.. :.. ..:. :: .:.. :. . ..: .
NP_001 ARSNSWMGSQGPMSQRRENYGVPPRRATISSWR--NDRMSTRHDGYATNDGNHPSCQETR
180 190 200 210 220
240 250 260
pF1KB6 DFFYEDRNHDDWSHDYDNRRDSSRDG--KWRSSRH
:. .:.. .. ..:: . : : . ::::
NP_001 DYAPPSRGYAYRDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESY
230 240 250 260 270 280
NP_001 SRGYRNRRSSRETREYAPPSRGHGYRDYGHSRRHESYSRGYSYHDGYGEALGRDHSEHLS
290 300 310 320 330 340
>>NP_005049 (OMIM: 400006,415000) RNA-binding motif prot (496 aa)
initn: 224 init1: 170 opt: 242 Z-score: 187.4 bits: 43.3 E(85289): 0.0011
Smith-Waterman score: 242; 25.0% identity (57.5% similar) in 268 aa overlap (7-265:3-263)
10 20 30 40 50
pF1KB6 MGAAAAEADRT--LFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFK
:::. ::.:.:. ...:..: .: . ::. .: . ::. .: . :::..:.
NP_005 MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRGFAFITFE
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 HEVSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPT-STSPSRY
. ... : . .:: .:.:. ::.. .... . :. . : : ::. : .:
NP_005 NPADAKNAAKDMNGKSLHGKAIKVE--QAKKPSFQSGGRRRPPASSRNRSPSGSLRSARG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ER--TMDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYG--GKFGSSPLDQSGFSPS
: : . : .. . .:. . .. .: .. : .. :. : .:. :
NP_005 SRGGTRGWLPSHEGHLDDGGYTPD---LKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 VQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGKRD
..:.: .:. :: :.. :.. ..:. :: .:.. :. . ..: .
NP_005 ARSNSWMGSQGPMSQRRENYGVPPRRATISSWR--NDRMSTRHDGYATNDGNHPSCQETR
180 190 200 210 220
240 250 260
pF1KB6 DFFYEDRNHDDWSHDYDNRRDSSRDG--KWRSSRH
:. .:.. .. ..:: . : : . ::::
NP_005 DYAPPSRGYAYRDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESY
230 240 250 260 270 280
NP_005 SRGYRNRRSSRETREYAPPSRGHGYRDYGHSRRHESYSRGYRNHPSSRETRDYAPPHRDY
290 300 310 320 330 340
>>XP_011529740 (OMIM: 400006,415000) PREDICTED: RNA-bind (385 aa)
initn: 224 init1: 170 opt: 235 Z-score: 183.9 bits: 42.3 E(85289): 0.0017
Smith-Waterman score: 235; 24.6% identity (56.2% similar) in 260 aa overlap (7-259:3-255)
10 20 30 40 50
pF1KB6 MGAAAAEADRT--LFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFK
:::. ::.:.:. ...:..: .: . ::. .: . ::. .: . :::..:.
XP_011 MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRGFAFITFE
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 HEVSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPT-STSPSRY
. ... : . .:: .:.:. ::.. . : :. . : : ::. : .:
XP_011 NPADAKNAAKDMNGKSLHGKAIKVEQAKKPSF--QSGGRRRPPASSRNRSPSGSLRSARG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ER--TMDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYG--GKFGSSPLDQSGFSPS
: : . : .. . .:. . .. .: .. : .. :. : .:. :
XP_011 SRGGTRGWLPSHEGHLDDGGYTPD---LKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 VQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGKRD
..:.: .:. :: :.. :.. ..:. :: .:.. :. . ..: .
XP_011 ARSNSWMGSQGPMSQRRENYGVPPRRATISSW--RNDRMSTRHDGYATNDGNHPSCQETR
180 190 200 210 220
240 250 260
pF1KB6 DFFYEDRNHDDWSHDYDNRRDSSRDGKWRSSRH
:. .:.. .. ..:: . : :
XP_011 DYAPPSRGYAYRDNGHSNRDEHSSRGYSYHDGYGEALGRDHSEHLSGSSYRDALQRYGTS
230 240 250 260 270 280
266 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:37:02 2016 done: Fri Nov 4 20:37:03 2016
Total Scan time: 7.290 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]