Result of FASTA (omim) for
pF1KB6256
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6256, 683 aa
1>>>pF1KB6256 683 - 683 aa - 683 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.5272+/-0.000514; mu= -35.3689+/- 0.032
mean_var=827.6137+/-167.713, 0's: 0 Z-trim(124.9): 58 B-trim: 0 in 0/61
Lambda= 0.044582
statistics sampled from 47304 (47426) to 47304 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.806), E-opt: 0.2 (0.556), width: 16
Scan time: 14.500
The best scores are: opt bits E(85289)
NP_009183 (OMIM: 601583,609062) POU domain, class ( 691) 4479 303.5 1.7e-81
XP_011513415 (OMIM: 601583,609062) PREDICTED: POU ( 720) 4479 303.5 1.8e-81
NP_001159490 (OMIM: 601583,609062) POU domain, cla ( 655) 3392 233.6 1.8e-60
>>NP_009183 (OMIM: 601583,609062) POU domain, class 6, t (691 aa)
initn: 4479 init1: 4479 opt: 4479 Z-score: 1584.0 bits: 303.5 E(85289): 1.7e-81
Smith-Waterman score: 4479; 100.0% identity (100.0% similar) in 683 aa overlap (1-683:9-691)
10 20 30 40 50
pF1KB6 MIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNEPLLAPVESNDSEDTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSALLQDPMIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNEPLLAPVESNDSEDTPS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 KLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 ILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 QLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 QLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 LASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB6 SGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB6 GQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB6 LEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB6 NTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB6 GSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQ
610 620 630 640 650 660
660 670 680
pF1KB6 ALKNTIKRLKQHEPATAVPLEPLTDSLEENS
:::::::::::::::::::::::::::::::
NP_009 ALKNTIKRLKQHEPATAVPLEPLTDSLEENS
670 680 690
>>XP_011513415 (OMIM: 601583,609062) PREDICTED: POU doma (720 aa)
initn: 4479 init1: 4479 opt: 4479 Z-score: 1583.7 bits: 303.5 E(85289): 1.8e-81
Smith-Waterman score: 4479; 100.0% identity (100.0% similar) in 683 aa overlap (1-683:38-720)
10 20 30
pF1KB6 MIAGQVSKPLLSVRSEMNAELRGEDKAATS
::::::::::::::::::::::::::::::
XP_011 SPFQRQHMMDCYLSAQQDTGTMQAVIGQDPMIAGQVSKPLLSVRSEMNAELRGEDKAATS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 DSELNEPLLAPVESNDSEDTPSKLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSELNEPLLAPVESNDSEDTPSKLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 AQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 GGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQ
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 PLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQ
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 SPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTN
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB6 AQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINT
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB6 QGITLSPIKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGITLSPIKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSS
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB6 ALSVGQLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALSVGQLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYS
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB6 QSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVL
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB6 ERWMAEAEARHRAGMQNLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERWMAEAEARHRAGMQNLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMT
610 620 630 640 650 660
640 650 660 670 680
pF1KB6 EIAEKLNYDREVVRVWFCNKRQALKNTIKRLKQHEPATAVPLEPLTDSLEENS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIAEKLNYDREVVRVWFCNKRQALKNTIKRLKQHEPATAVPLEPLTDSLEENS
670 680 690 700 710 720
>>NP_001159490 (OMIM: 601583,609062) POU domain, class 6 (655 aa)
initn: 3387 init1: 3387 opt: 3392 Z-score: 1206.4 bits: 233.6 E(85289): 1.8e-60
Smith-Waterman score: 4165; 94.7% identity (94.7% similar) in 683 aa overlap (1-683:9-655)
10 20 30 40 50
pF1KB6 MIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNEPLLAPVESNDSEDTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSALLQDPMIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNEPLLAPVESNDSEDTPS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 KLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 ILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 QLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 QLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 LASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB6 SGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB6 GQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB6 LEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQE
::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICR----------------
490 500 510 520
540 550 560 570 580 590
pF1KB6 NTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFI
::::::::::::::::::::::::::::::::::::::::
NP_001 --------------------FEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFI
530 540 550 560
600 610 620 630 640 650
pF1KB6 GSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQ
570 580 590 600 610 620
660 670 680
pF1KB6 ALKNTIKRLKQHEPATAVPLEPLTDSLEENS
:::::::::::::::::::::::::::::::
NP_001 ALKNTIKRLKQHEPATAVPLEPLTDSLEENS
630 640 650
683 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:22:24 2016 done: Sat Nov 5 08:22:26 2016
Total Scan time: 14.500 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]