FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6235, 749 aa 1>>>pF1KB6235 749 - 749 aa - 749 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3226+/-0.000417; mu= 15.9671+/- 0.026 mean_var=94.5560+/-19.209, 0's: 0 Z-trim(111.1): 61 B-trim: 0 in 0/59 Lambda= 0.131895 statistics sampled from 19551 (19611) to 19551 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.58), E-opt: 0.2 (0.23), width: 16 Scan time: 11.880 The best scores are: opt bits E(85289) NP_602304 (OMIM: 601337) transcription factor RFX3 ( 749) 4907 944.8 0 NP_001269045 (OMIM: 601337) transcription factor R ( 749) 4907 944.8 0 NP_002910 (OMIM: 601337) transcription factor RFX3 ( 707) 4299 829.1 0 XP_011516300 (OMIM: 601337) PREDICTED: transcripti ( 770) 4299 829.1 0 XP_006716908 (OMIM: 601337) PREDICTED: transcripti ( 770) 4299 829.1 0 XP_006716907 (OMIM: 601337) PREDICTED: transcripti ( 770) 4299 829.1 0 XP_006716906 (OMIM: 601337) PREDICTED: transcripti ( 770) 4299 829.1 0 XP_016870489 (OMIM: 601337) PREDICTED: transcripti ( 770) 4299 829.1 0 XP_011516301 (OMIM: 601337) PREDICTED: transcripti ( 770) 4299 829.1 0 XP_006716903 (OMIM: 601337) PREDICTED: transcripti ( 780) 4299 829.1 0 XP_016870490 (OMIM: 601337) PREDICTED: transcripti ( 724) 3801 734.3 4.1e-211 XP_011516303 (OMIM: 601337) PREDICTED: transcripti ( 687) 3781 730.5 5.5e-210 XP_011516302 (OMIM: 601337) PREDICTED: transcripti ( 745) 3193 618.6 2.8e-176 XP_011526473 (OMIM: 142765) PREDICTED: DNA-binding ( 723) 3016 584.9 3.8e-166 NP_000626 (OMIM: 142765) DNA-binding protein RFX2 ( 723) 3016 584.9 3.8e-166 XP_016882596 (OMIM: 142765) PREDICTED: DNA-binding ( 678) 3009 583.6 9.1e-166 XP_011526474 (OMIM: 142765) PREDICTED: DNA-binding ( 687) 2976 577.3 7.1e-164 NP_001269046 (OMIM: 601337) transcription factor R ( 413) 2609 507.4 4.9e-143 NP_602309 (OMIM: 142765) DNA-binding protein RFX2 ( 698) 2551 496.4 1.6e-139 XP_016882597 (OMIM: 142765) PREDICTED: DNA-binding ( 653) 2533 493.0 1.6e-138 XP_006716910 (OMIM: 601337) PREDICTED: transcripti ( 492) 2472 481.3 4e-135 XP_016870491 (OMIM: 601337) PREDICTED: transcripti ( 501) 2457 478.5 2.9e-134 NP_002909 (OMIM: 600006) MHC class II regulatory f ( 979) 2440 475.4 4.8e-133 XP_011526472 (OMIM: 600006) PREDICTED: MHC class I ( 980) 2435 474.5 9.3e-133 XP_011526471 (OMIM: 600006) PREDICTED: MHC class I ( 980) 2435 474.5 9.3e-133 XP_011526467 (OMIM: 600006) PREDICTED: MHC class I (1089) 2435 474.5 1e-132 XP_011526469 (OMIM: 600006) PREDICTED: MHC class I (1089) 2435 474.5 1e-132 XP_011526468 (OMIM: 600006) PREDICTED: MHC class I (1089) 2435 474.5 1e-132 XP_011526470 (OMIM: 600006) PREDICTED: MHC class I ( 991) 2389 465.7 4.1e-130 NP_115880 (OMIM: 603958) transcription factor RFX4 ( 641) 548 115.3 8.1e-25 NP_998759 (OMIM: 603958) transcription factor RFX4 ( 735) 347 77.1 3e-13 NP_001193620 (OMIM: 603958) transcription factor R ( 744) 347 77.1 3e-13 XP_016865966 (OMIM: 612659,615710) PREDICTED: DNA- ( 802) 319 71.8 1.3e-11 XP_011533891 (OMIM: 612659,615710) PREDICTED: DNA- ( 892) 319 71.8 1.4e-11 NP_775831 (OMIM: 612659,615710) DNA-binding protei ( 928) 319 71.8 1.4e-11 XP_005254660 (OMIM: 612660) PREDICTED: DNA-binding (1460) 231 55.2 2.3e-06 NP_073752 (OMIM: 612660) DNA-binding protein RFX7 (1460) 231 55.2 2.3e-06 XP_016877995 (OMIM: 612660) PREDICTED: DNA-binding (1460) 231 55.2 2.3e-06 XP_016877997 (OMIM: 612660) PREDICTED: DNA-binding (1363) 224 53.8 5.5e-06 XP_011520227 (OMIM: 612660) PREDICTED: DNA-binding (1363) 224 53.8 5.5e-06 XP_016877996 (OMIM: 612660) PREDICTED: DNA-binding (1363) 224 53.8 5.5e-06 XP_005245462 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 207 50.4 2.7e-05 XP_005245463 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 207 50.4 2.7e-05 XP_011508149 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 207 50.4 2.7e-05 XP_011508150 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 207 50.4 2.7e-05 XP_011508152 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 207 50.4 2.7e-05 NP_001020774 (OMIM: 209920,601863) DNA-binding pro ( 616) 207 50.4 2.7e-05 NP_000440 (OMIM: 209920,601863) DNA-binding protei ( 616) 207 50.4 2.7e-05 XP_011508151 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 207 50.4 2.7e-05 >>NP_602304 (OMIM: 601337) transcription factor RFX3 iso (749 aa) initn: 4907 init1: 4907 opt: 4907 Z-score: 5048.3 bits: 944.8 E(85289): 0 Smith-Waterman score: 4907; 100.0% identity (100.0% similar) in 749 aa overlap (1-749:1-749) 10 20 30 40 50 60 pF1KB6 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEFGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEFGDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 NAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_602 NAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSL 670 680 690 700 710 720 730 740 pF1KB6 LNPIHSEHIVTSTQTIRQCSATGNTYTAV ::::::::::::::::::::::::::::: NP_602 LNPIHSEHIVTSTQTIRQCSATGNTYTAV 730 740 >>NP_001269045 (OMIM: 601337) transcription factor RFX3 (749 aa) initn: 4907 init1: 4907 opt: 4907 Z-score: 5048.3 bits: 944.8 E(85289): 0 Smith-Waterman score: 4907; 100.0% identity (100.0% similar) in 749 aa overlap (1-749:1-749) 10 20 30 40 50 60 pF1KB6 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEFGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEFGDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 NAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSL 670 680 690 700 710 720 730 740 pF1KB6 LNPIHSEHIVTSTQTIRQCSATGNTYTAV ::::::::::::::::::::::::::::: NP_001 LNPIHSEHIVTSTQTIRQCSATGNTYTAV 730 740 >>NP_002910 (OMIM: 601337) transcription factor RFX3 iso (707 aa) initn: 4299 init1: 4299 opt: 4299 Z-score: 4423.4 bits: 829.1 E(85289): 0 Smith-Waterman score: 4299; 100.0% identity (100.0% similar) in 656 aa overlap (1-656:1-656) 10 20 30 40 50 60 pF1KB6 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB6 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEFGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEVREA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB6 NAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSL NP_002 ERAVTHWVIKNKPELHFSLNTLLIKTMVPNQVSLRARRDCGVIARVP 670 680 690 700 >>XP_011516300 (OMIM: 601337) PREDICTED: transcription f (770 aa) initn: 4299 init1: 4299 opt: 4299 Z-score: 4422.9 bits: 829.1 E(85289): 0 Smith-Waterman score: 4855; 97.3% identity (97.3% similar) in 770 aa overlap (1-749:1-770) 10 20 30 40 50 60 pF1KB6 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGE---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGETNLV 610 620 630 640 650 660 660 670 680 690 pF1KB6 -----------------FGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL ::::::::::::::::::::::::::::::::::::::::::: XP_011 DEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL 670 680 690 700 710 720 700 710 720 730 740 pF1KB6 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV 730 740 750 760 770 >>XP_006716908 (OMIM: 601337) PREDICTED: transcription f (770 aa) initn: 4299 init1: 4299 opt: 4299 Z-score: 4422.9 bits: 829.1 E(85289): 0 Smith-Waterman score: 4855; 97.3% identity (97.3% similar) in 770 aa overlap (1-749:1-770) 10 20 30 40 50 60 pF1KB6 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGE---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGETNLV 610 620 630 640 650 660 660 670 680 690 pF1KB6 -----------------FGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL ::::::::::::::::::::::::::::::::::::::::::: XP_006 DEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL 670 680 690 700 710 720 700 710 720 730 740 pF1KB6 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV 730 740 750 760 770 >>XP_006716907 (OMIM: 601337) PREDICTED: transcription f (770 aa) initn: 4299 init1: 4299 opt: 4299 Z-score: 4422.9 bits: 829.1 E(85289): 0 Smith-Waterman score: 4855; 97.3% identity (97.3% similar) in 770 aa overlap (1-749:1-770) 10 20 30 40 50 60 pF1KB6 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGE---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGETNLV 610 620 630 640 650 660 660 670 680 690 pF1KB6 -----------------FGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL ::::::::::::::::::::::::::::::::::::::::::: XP_006 DEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL 670 680 690 700 710 720 700 710 720 730 740 pF1KB6 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV 730 740 750 760 770 >>XP_006716906 (OMIM: 601337) PREDICTED: transcription f (770 aa) initn: 4299 init1: 4299 opt: 4299 Z-score: 4422.9 bits: 829.1 E(85289): 0 Smith-Waterman score: 4855; 97.3% identity (97.3% similar) in 770 aa overlap (1-749:1-770) 10 20 30 40 50 60 pF1KB6 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGE---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGETNLV 610 620 630 640 650 660 660 670 680 690 pF1KB6 -----------------FGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL ::::::::::::::::::::::::::::::::::::::::::: XP_006 DEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL 670 680 690 700 710 720 700 710 720 730 740 pF1KB6 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV 730 740 750 760 770 >>XP_016870489 (OMIM: 601337) PREDICTED: transcription f (770 aa) initn: 4299 init1: 4299 opt: 4299 Z-score: 4422.9 bits: 829.1 E(85289): 0 Smith-Waterman score: 4855; 97.3% identity (97.3% similar) in 770 aa overlap (1-749:1-770) 10 20 30 40 50 60 pF1KB6 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGE---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGETNLV 610 620 630 640 650 660 660 670 680 690 pF1KB6 -----------------FGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL ::::::::::::::::::::::::::::::::::::::::::: XP_016 DEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL 670 680 690 700 710 720 700 710 720 730 740 pF1KB6 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV 730 740 750 760 770 >>XP_011516301 (OMIM: 601337) PREDICTED: transcription f (770 aa) initn: 4299 init1: 4299 opt: 4299 Z-score: 4422.9 bits: 829.1 E(85289): 0 Smith-Waterman score: 4855; 97.3% identity (97.3% similar) in 770 aa overlap (1-749:1-770) 10 20 30 40 50 60 pF1KB6 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB6 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB6 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB6 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLK 550 560 570 580 590 600 610 620 630 640 650 pF1KB6 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGE---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGETNLV 610 620 630 640 650 660 660 670 680 690 pF1KB6 -----------------FGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL ::::::::::::::::::::::::::::::::::::::::::: XP_011 DEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTEL 670 680 690 700 710 720 700 710 720 730 740 pF1KB6 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV 730 740 750 760 770 >>XP_006716903 (OMIM: 601337) PREDICTED: transcription f (780 aa) initn: 4299 init1: 4299 opt: 4299 Z-score: 4422.8 bits: 829.1 E(85289): 0 Smith-Waterman score: 4855; 97.3% identity (97.3% similar) in 770 aa overlap (1-749:11-780) 10 20 30 40 50 pF1KB6 MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKVLNLKQTIMQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 HVYPAQVQYVEGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HVYPAQVQYVEGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SMVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SMVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 GLSTHRSSLLNSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLSTHRSSLLNSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 SIFMGLRTRRLGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SIFMGLRTRRLGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 VDGVADGFTGSGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VDGVADGFTGSGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDI 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 KSLQSLYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KSLQSLYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB6 PKAKLITLCKHESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PKAKLITLCKHESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB6 SNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVD 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB6 FANVQEQASWVCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FANVQEQASWVCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSF 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB6 PKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETP 610 620 630 640 650 660 660 670 680 pF1KB6 IAVMGE---------------------FGDLNAVSPGNLDKDEGSEVESEMDEELDDSSE :::::: ::::::::::::::::::::::::::::::::: XP_006 IAVMGETNLVDEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSE 670 680 690 700 710 720 690 700 710 720 730 740 pF1KB6 PQAKREKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PQAKREKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV 730 740 750 760 770 780 749 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:21:04 2016 done: Sat Nov 5 14:21:06 2016 Total Scan time: 11.880 Total Display time: 0.270 Function used was FASTA [36.3.4 Apr, 2011]