Result of FASTA (omim) for
pF1KB6176
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6176, 606 aa
1>>>pF1KB6176 606 - 606 aa - 606 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9828+/-0.000486; mu= 5.8857+/- 0.030
mean_var=693.1709+/-160.168, 0's: 0 Z-trim(119.8): 1271 B-trim: 0 in 0/57
Lambda= 0.048714
statistics sampled from 32441 (34328) to 32441 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.402), width: 16
Scan time: 11.050
The best scores are: opt bits E(85289)
XP_011542210 (OMIM: 311010) PREDICTED: serine/thre ( 606) 4125 306.1 2.3e-82
NP_001645 (OMIM: 311010) serine/threonine-protein ( 606) 4125 306.1 2.3e-82
NP_001243125 (OMIM: 311010) serine/threonine-prote ( 609) 4109 305.0 5e-82
XP_006724592 (OMIM: 311010) PREDICTED: serine/thre ( 611) 4105 304.7 6.1e-82
XP_011542208 (OMIM: 311010) PREDICTED: serine/thre ( 611) 4105 304.7 6.1e-82
XP_011542211 (OMIM: 311010) PREDICTED: serine/thre ( 387) 2586 197.6 6.8e-50
XP_005265412 (OMIM: 164760,611553,611554,615916) P ( 648) 2457 188.9 4.6e-47
NP_002871 (OMIM: 164760,611553,611554,615916) RAF ( 648) 2457 188.9 4.6e-47
XP_011532276 (OMIM: 164760,611553,611554,615916) P ( 648) 2457 188.9 4.6e-47
XP_005265415 (OMIM: 164760,611553,611554,615916) P ( 567) 2221 172.2 4.2e-42
XP_011532277 (OMIM: 164760,611553,611554,615916) P ( 567) 2221 172.2 4.2e-42
XP_005265416 (OMIM: 164760,611553,611554,615916) P ( 534) 1825 144.3 9.8e-34
XP_005265414 (OMIM: 164760,611553,611554,615916) P ( 615) 1825 144.4 1e-33
XP_016862455 (OMIM: 164760,611553,611554,615916) P ( 615) 1825 144.4 1e-33
NP_004324 (OMIM: 115150,163950,164757,211980,61370 ( 766) 1781 141.5 9.8e-33
XP_005250102 (OMIM: 115150,163950,164757,211980,61 ( 767) 1781 141.5 9.8e-33
XP_016868047 (OMIM: 115150,163950,164757,211980,61 ( 807) 1672 133.9 2e-30
XP_016868048 (OMIM: 115150,163950,164757,211980,61 ( 798) 1538 124.5 1.4e-27
NP_001243126 (OMIM: 311010) serine/threonine-prote ( 186) 1287 105.7 1.5e-22
XP_006722217 (OMIM: 601132) PREDICTED: kinase supp ( 887) 557 55.6 8.2e-07
XP_016874699 (OMIM: 610737) PREDICTED: kinase supp ( 515) 547 54.5 1.1e-06
XP_011536530 (OMIM: 610737) PREDICTED: kinase supp ( 647) 547 54.7 1.2e-06
XP_011536527 (OMIM: 610737) PREDICTED: kinase supp ( 829) 547 54.9 1.3e-06
XP_016880757 (OMIM: 601132) PREDICTED: kinase supp ( 901) 547 54.9 1.3e-06
NP_775869 (OMIM: 610737) kinase suppressor of Ras ( 921) 547 55.0 1.4e-06
XP_011536526 (OMIM: 610737) PREDICTED: kinase supp ( 948) 547 55.0 1.4e-06
XP_016880758 (OMIM: 601132) PREDICTED: kinase supp ( 876) 540 54.4 1.9e-06
XP_016880756 (OMIM: 601132) PREDICTED: kinase supp ( 909) 531 53.8 3e-06
XP_016880767 (OMIM: 601132) PREDICTED: kinase supp ( 587) 514 52.3 5.6e-06
XP_016880766 (OMIM: 601132) PREDICTED: kinase supp ( 605) 514 52.3 5.7e-06
XP_016866141 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 511 52.0 6.2e-06
XP_016866143 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 511 52.0 6.2e-06
XP_016866140 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 511 52.0 6.2e-06
NP_002028 (OMIM: 137025) tyrosine-protein kinase F ( 537) 511 52.0 6.2e-06
XP_016866139 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 511 52.0 6.2e-06
XP_016866142 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 511 52.0 6.2e-06
XP_016880760 (OMIM: 601132) PREDICTED: kinase supp ( 786) 514 52.5 6.3e-06
XP_016880762 (OMIM: 601132) PREDICTED: kinase supp ( 786) 514 52.5 6.3e-06
XP_016880765 (OMIM: 601132) PREDICTED: kinase supp ( 786) 514 52.5 6.3e-06
XP_016880763 (OMIM: 601132) PREDICTED: kinase supp ( 786) 514 52.5 6.3e-06
XP_016880761 (OMIM: 601132) PREDICTED: kinase supp ( 786) 514 52.5 6.3e-06
XP_016880764 (OMIM: 601132) PREDICTED: kinase supp ( 786) 514 52.5 6.3e-06
XP_016880759 (OMIM: 601132) PREDICTED: kinase supp ( 804) 514 52.5 6.4e-06
XP_011523731 (OMIM: 601132) PREDICTED: kinase supp ( 923) 514 52.6 6.8e-06
NP_055053 (OMIM: 601132) kinase suppressor of Ras ( 762) 511 52.3 7.2e-06
XP_011523732 (OMIM: 601132) PREDICTED: kinase supp ( 899) 511 52.4 7.8e-06
XP_011523733 (OMIM: 601132) PREDICTED: kinase supp ( 898) 507 52.1 9.5e-06
XP_011533958 (OMIM: 606573) PREDICTED: tyrosine-pr ( 392) 498 50.8 1e-05
XP_016866134 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 498 51.0 1.1e-05
NP_002022 (OMIM: 606573) tyrosine-protein kinase F ( 505) 498 51.0 1.1e-05
>>XP_011542210 (OMIM: 311010) PREDICTED: serine/threonin (606 aa)
initn: 4125 init1: 4125 opt: 4125 Z-score: 1599.8 bits: 306.1 E(85289): 2.3e-82
Smith-Waterman score: 4125; 100.0% identity (100.0% similar) in 606 aa overlap (1-606:1-606)
10 20 30 40 50 60
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 TPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 YYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 TRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 HAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 QDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 AMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLS
550 560 570 580 590 600
pF1KB6 AARLVP
::::::
XP_011 AARLVP
>>NP_001645 (OMIM: 311010) serine/threonine-protein kina (606 aa)
initn: 4125 init1: 4125 opt: 4125 Z-score: 1599.8 bits: 306.1 E(85289): 2.3e-82
Smith-Waterman score: 4125; 100.0% identity (100.0% similar) in 606 aa overlap (1-606:1-606)
10 20 30 40 50 60
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 TPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 YYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 TRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 HAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 QDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 AMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLS
550 560 570 580 590 600
pF1KB6 AARLVP
::::::
NP_001 AARLVP
>>NP_001243125 (OMIM: 311010) serine/threonine-protein k (609 aa)
initn: 3063 init1: 3063 opt: 4109 Z-score: 1593.7 bits: 305.0 E(85289): 5e-82
Smith-Waterman score: 4109; 99.5% identity (99.5% similar) in 609 aa overlap (1-606:1-609)
10 20 30 40 50 60
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQ---FYHSVQDLSGGSRQHEAPSNRPLN
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQPSRFYHSVQDLSGGSRQHEAPSNRPLN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 ELLTPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLTPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 SFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYR
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 DSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB6 LRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGM
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB6 DYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB6 IRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSN
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB6 CPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPAC
550 560 570 580 590 600
600
pF1KB6 LLSAARLVP
:::::::::
NP_001 LLSAARLVP
>>XP_006724592 (OMIM: 311010) PREDICTED: serine/threonin (611 aa)
initn: 2838 init1: 2838 opt: 4105 Z-score: 1592.1 bits: 304.7 E(85289): 6.1e-82
Smith-Waterman score: 4105; 99.2% identity (99.2% similar) in 611 aa overlap (1-606:1-611)
10 20 30 40 50 60
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 TPQGPS-----PRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLT
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPQGPSLSPGSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 GQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLG
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEM
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB6 QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB6 GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB6 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKIS
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB6 SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
550 560 570 580 590 600
600
pF1KB6 ACLLSAARLVP
:::::::::::
XP_006 ACLLSAARLVP
610
>>XP_011542208 (OMIM: 311010) PREDICTED: serine/threonin (611 aa)
initn: 2838 init1: 2838 opt: 4105 Z-score: 1592.1 bits: 304.7 E(85289): 6.1e-82
Smith-Waterman score: 4105; 99.2% identity (99.2% similar) in 611 aa overlap (1-606:1-611)
10 20 30 40 50 60
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 TPQGPS-----PRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLT
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPQGPSLSPGSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 GQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLG
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEM
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB6 QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB6 GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB6 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKIS
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB6 SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
550 560 570 580 590 600
600
pF1KB6 ACLLSAARLVP
:::::::::::
XP_011 ACLLSAARLVP
610
>>XP_011542211 (OMIM: 311010) PREDICTED: serine/threonin (387 aa)
initn: 2586 init1: 2586 opt: 2586 Z-score: 1016.8 bits: 197.6 E(85289): 6.8e-50
Smith-Waterman score: 2586; 100.0% identity (100.0% similar) in 387 aa overlap (220-606:1-387)
190 200 210 220 230 240
pF1KB6 QHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGG
::::::::::::::::::::::::::::::
XP_011 MVSTTAPMDSNLIQLTGQSFSTDAAGSRGG
10 20 30
250 260 270 280 290 300
pF1KB6 SDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSE
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB6 VQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLF
100 110 120 130 140 150
370 380 390 400 410 420
pF1KB6 MGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRD
160 170 180 190 200 210
430 440 450 460 470 480
pF1KB6 LKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQ
220 230 240 250 260 270
490 500 510 520 530 540
pF1KB6 SDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDC
280 290 300 310 320 330
550 560 570 580 590 600
pF1KB6 LKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
340 350 360 370 380
>>XP_005265412 (OMIM: 164760,611553,611554,615916) PREDI (648 aa)
initn: 2208 init1: 1617 opt: 2457 Z-score: 966.0 bits: 188.9 E(85289): 4.6e-47
Smith-Waterman score: 2457; 61.9% identity (81.1% similar) in 607 aa overlap (13-606:50-646)
10 20 30 40
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVY
.::.. .:..:.:::::::::.::.:::..
XP_005 AVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLH
20 30 40 50 60 70
50 60 70 80 90
pF1KB6 DSLDKALKVRGLNQDCCVVYRLI---KGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMH
: : ::::::::. .::.:.::. ::.:. :.: : : :::: :. :. :::: :
XP_005 DCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB6 NFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQ
::.::::..:::::.: :::..::::::::::::.:::.::::.::: :. :: . .
XP_005 NFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNS
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB6 DLSGGSRQHEAPS--NRPLNELLTPQGPSPRTQHCDPEHFPF----PAPANAPLQRIRST
. : : :: : . : .. . : . .. :. : : :. .. :: :::
XP_005 TI-GDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRST
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB6 STPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVS-SGRKSPHS
::::::::::: :.:: .:. :: :.. : . : :: ..: .: ..:..
XP_005 STPNVHMVSTTLPVDSRMIE--------DAIRSHSESASPSALSSSPNNLSPTGWSQPKT
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB6 KSPAEQRERKSLA--DDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWH
:: :::: .. ..:.:.. : :::.::::. :::.: :::.::::::..:.::
XP_005 PVPA-QRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWH
320 330 340 350 360
340 350 360 370 380 390
pF1KB6 GDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSL
::::::.::: .:: :: :::.::. :::::::::::::::.::. ..::.:::::::::
XP_005 GDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB6 YHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGL
:.:::: .:.:.: ::::.::::::::::::::::::::.::::::::::::::::::::
XP_005 YKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB6 ATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYS
::::.::::.: .:::.::::::: ::::::: ::.:::::::.::.:::::::: ::::
XP_005 ATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYS
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB6 HIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELL
::. :::::::::::: ::::::. .::::::.::..::.: .::::::::::..::::
XP_005 HINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELL
550 560 570 580 590 600
580 590 600
pF1KB6 QRSLPKIERSASEPSLHRT-QADELPACLLSAARLVP
:.:::::.::::::::::. ..... :: :... .:
XP_005 QHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
610 620 630 640
>>NP_002871 (OMIM: 164760,611553,611554,615916) RAF prot (648 aa)
initn: 2208 init1: 1617 opt: 2457 Z-score: 966.0 bits: 188.9 E(85289): 4.6e-47
Smith-Waterman score: 2457; 61.9% identity (81.1% similar) in 607 aa overlap (13-606:50-646)
10 20 30 40
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVY
.::.. .:..:.:::::::::.::.:::..
NP_002 AVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLH
20 30 40 50 60 70
50 60 70 80 90
pF1KB6 DSLDKALKVRGLNQDCCVVYRLI---KGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMH
: : ::::::::. .::.:.::. ::.:. :.: : : :::: :. :. :::: :
NP_002 DCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB6 NFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQ
::.::::..:::::.: :::..::::::::::::.:::.::::.::: :. :: . .
NP_002 NFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNS
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB6 DLSGGSRQHEAPS--NRPLNELLTPQGPSPRTQHCDPEHFPF----PAPANAPLQRIRST
. : : :: : . : .. . : . .. :. : : :. .. :: :::
NP_002 TI-GDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRST
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB6 STPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVS-SGRKSPHS
::::::::::: :.:: .:. :: :.. : . : :: ..: .: ..:..
NP_002 STPNVHMVSTTLPVDSRMIE--------DAIRSHSESASPSALSSSPNNLSPTGWSQPKT
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB6 KSPAEQRERKSLA--DDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWH
:: :::: .. ..:.:.. : :::.::::. :::.: :::.::::::..:.::
NP_002 PVPA-QRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWH
320 330 340 350 360
340 350 360 370 380 390
pF1KB6 GDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSL
::::::.::: .:: :: :::.::. :::::::::::::::.::. ..::.:::::::::
NP_002 GDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB6 YHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGL
:.:::: .:.:.: ::::.::::::::::::::::::::.::::::::::::::::::::
NP_002 YKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB6 ATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYS
::::.::::.: .:::.::::::: ::::::: ::.:::::::.::.:::::::: ::::
NP_002 ATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYS
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB6 HIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELL
::. :::::::::::: ::::::. .::::::.::..::.: .::::::::::..::::
NP_002 HINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELL
550 560 570 580 590 600
580 590 600
pF1KB6 QRSLPKIERSASEPSLHRT-QADELPACLLSAARLVP
:.:::::.::::::::::. ..... :: :... .:
NP_002 QHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
610 620 630 640
>>XP_011532276 (OMIM: 164760,611553,611554,615916) PREDI (648 aa)
initn: 2208 init1: 1617 opt: 2457 Z-score: 966.0 bits: 188.9 E(85289): 4.6e-47
Smith-Waterman score: 2457; 61.9% identity (81.1% similar) in 607 aa overlap (13-606:50-646)
10 20 30 40
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVY
.::.. .:..:.:::::::::.::.:::..
XP_011 AVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLH
20 30 40 50 60 70
50 60 70 80 90
pF1KB6 DSLDKALKVRGLNQDCCVVYRLI---KGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMH
: : ::::::::. .::.:.::. ::.:. :.: : : :::: :. :. :::: :
XP_011 DCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB6 NFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQ
::.::::..:::::.: :::..::::::::::::.:::.::::.::: :. :: . .
XP_011 NFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNS
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB6 DLSGGSRQHEAPS--NRPLNELLTPQGPSPRTQHCDPEHFPF----PAPANAPLQRIRST
. : : :: : . : .. . : . .. :. : : :. .. :: :::
XP_011 TI-GDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRST
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB6 STPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVS-SGRKSPHS
::::::::::: :.:: .:. :: :.. : . : :: ..: .: ..:..
XP_011 STPNVHMVSTTLPVDSRMIE--------DAIRSHSESASPSALSSSPNNLSPTGWSQPKT
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB6 KSPAEQRERKSLA--DDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWH
:: :::: .. ..:.:.. : :::.::::. :::.: :::.::::::..:.::
XP_011 PVPA-QRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWH
320 330 340 350 360
340 350 360 370 380 390
pF1KB6 GDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSL
::::::.::: .:: :: :::.::. :::::::::::::::.::. ..::.:::::::::
XP_011 GDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB6 YHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGL
:.:::: .:.:.: ::::.::::::::::::::::::::.::::::::::::::::::::
XP_011 YKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB6 ATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYS
::::.::::.: .:::.::::::: ::::::: ::.:::::::.::.:::::::: ::::
XP_011 ATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYS
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB6 HIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELL
::. :::::::::::: ::::::. .::::::.::..::.: .::::::::::..::::
XP_011 HINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELL
550 560 570 580 590 600
580 590 600
pF1KB6 QRSLPKIERSASEPSLHRT-QADELPACLLSAARLVP
:.:::::.::::::::::. ..... :: :... .:
XP_011 QHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
610 620 630 640
>>XP_005265415 (OMIM: 164760,611553,611554,615916) PREDI (567 aa)
initn: 2205 init1: 1617 opt: 2221 Z-score: 876.8 bits: 172.2 E(85289): 4.2e-42
Smith-Waterman score: 2221; 62.1% identity (80.3% similar) in 549 aa overlap (68-606:27-565)
40 50 60 70 80 90
pF1KB6 GMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLT
.:. :.: : : :::: :. :. ::::
XP_005 MMANSQILLRQATLSVFSCRTSKEQCKKARLDWNTDAASLIGEELQVDFLDHVPLT
10 20 30 40 50
100 110 120 130 140 150
pF1KB6 MHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHS
:::.::::..:::::.: :::..::::::::::::.:::.::::.::: :. :: .
XP_005 THNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFP
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB6 VQDLSGGSRQHEAPS--NRPLNELLTPQGPSPRTQHCDPEHFPF----PAPANAPLQRIR
. . : : :: : . : .. . : . .. :. : : :. .. :: :
XP_005 NSTI-GDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQR
120 130 140 150 160 170
220 230 240 250 260 270
pF1KB6 STSTPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVS-SGRKSP
::::::::::::: :.:: .:. :: :.. : . : :: ..: .: ..:
XP_005 STSTPNVHMVSTTLPVDSRMIE--------DAIRSHSESASPSALSSSPNNLSPTGWSQP
180 190 200 210 220
280 290 300 310 320
pF1KB6 HSKSPAEQRERKSLA--DDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGR
.. :: :::: .. ..:.:.. : :::.::::. :::.: :::.::::::..:.
XP_005 KTPVPA-QRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGK
230 240 250 260 270 280
330 340 350 360 370 380
pF1KB6 WHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGS
::::::::.::: .:: :: :::.::. :::::::::::::::.::. ..::.:::::::
XP_005 WHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGS
290 300 310 320 330 340
390 400 410 420 430 440
pF1KB6 SLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDF
:::.:::: .:.:.: ::::.::::::::::::::::::::.::::::::::::::::::
XP_005 SLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDF
350 360 370 380 390 400
450 460 470 480 490 500
pF1KB6 GLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLP
::::::.::::.: .:::.::::::: ::::::: ::.:::::::.::.:::::::: ::
XP_005 GLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELP
410 420 430 440 450 460
510 520 530 540 550 560
pF1KB6 YSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIE
::::. :::::::::::: ::::::. .::::::.::..::.: .::::::::::..::
XP_005 YSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIE
470 480 490 500 510 520
570 580 590 600
pF1KB6 LLQRSLPKIERSASEPSLHRT-QADELPACLLSAARLVP
:::.:::::.::::::::::. ..... :: :... .:
XP_005 LLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
530 540 550 560
606 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:33:30 2016 done: Sat Nov 5 20:33:32 2016
Total Scan time: 11.050 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]