Result of FASTA (omim) for pF1KB6143
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6143, 595 aa
  1>>>pF1KB6143 595 - 595 aa - 595 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2159+/-0.000472; mu= 10.8470+/- 0.029
 mean_var=164.3339+/-36.120, 0's: 0 Z-trim(114.1): 113  B-trim: 1431 in 1/54
 Lambda= 0.100049
 statistics sampled from 23703 (23825) to 23703 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.279), width:  16
 Scan time: 10.360

The best scores are:                                      opt bits E(85289)
NP_057308 (OMIM: 605952) sorting nexin-9 [Homo sap ( 595) 4030 594.6 3.1e-169
XP_005267072 (OMIM: 605952) PREDICTED: sorting nex ( 588) 3990 588.8 1.7e-167
XP_011534188 (OMIM: 605952) PREDICTED: sorting nex ( 501) 3377 500.3 6.5e-141
XP_016867572 (OMIM: 614905) PREDICTED: sorting nex ( 412)  197 41.2  0.0084
XP_016867573 (OMIM: 614905) PREDICTED: sorting nex ( 412)  197 41.2  0.0084
XP_011513632 (OMIM: 614905) PREDICTED: sorting nex ( 451)  197 41.2   0.009
XP_011513631 (OMIM: 614905) PREDICTED: sorting nex ( 457)  197 41.2  0.0091
NP_037453 (OMIM: 614905) sorting nexin-8 [Homo sap ( 465)  197 41.2  0.0092


>>NP_057308 (OMIM: 605952) sorting nexin-9 [Homo sapiens  (595 aa)
 initn: 4030 init1: 4030 opt: 4030  Z-score: 3159.2  bits: 594.6 E(85289): 3.1e-169
Smith-Waterman score: 4030; 100.0% identity (100.0% similar) in 595 aa overlap (1-595:1-595)

               10        20        30        40        50        60
pF1KB6 MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR
              490       500       510       520       530       540

              550       560       570       580       590     
pF1KB6 VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
              550       560       570       580       590     

>>XP_005267072 (OMIM: 605952) PREDICTED: sorting nexin-9  (588 aa)
 initn: 3990 init1: 3990 opt: 3990  Z-score: 3128.1  bits: 588.8 E(85289): 1.7e-167
Smith-Waterman score: 3990; 100.0% identity (100.0% similar) in 588 aa overlap (8-595:1-588)

               10        20        30        40        50        60
pF1KB6 MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005        MYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL
                      10        20        30        40        50   

               70        80        90       100       110       120
pF1KB6 PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE
            60        70        80        90       100       110   

              130       140       150       160       170       180
pF1KB6 SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD
           120       130       140       150       160       170   

              190       200       210       220       230       240
pF1KB6 SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG
           180       190       200       210       220       230   

              250       260       270       280       290       300
pF1KB6 PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK
           240       250       260       270       280       290   

              310       320       330       340       350       360
pF1KB6 FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK
           300       310       320       330       340       350   

              370       380       390       400       410       420
pF1KB6 EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG
           360       370       380       390       400       410   

              430       440       450       460       470       480
pF1KB6 QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE
           420       430       440       450       460       470   

              490       500       510       520       530       540
pF1KB6 QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR
           480       490       500       510       520       530   

              550       560       570       580       590     
pF1KB6 VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
           540       550       560       570       580        

>>XP_011534188 (OMIM: 605952) PREDICTED: sorting nexin-9  (501 aa)
 initn: 3377 init1: 3377 opt: 3377  Z-score: 2650.8  bits: 500.3 E(85289): 6.5e-141
Smith-Waterman score: 3377; 100.0% identity (100.0% similar) in 495 aa overlap (101-595:7-501)

               80        90       100       110       120       130
pF1KB6 GNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWESSEGWGAQPE
                                     ::::::::::::::::::::::::::::::
XP_011                         MKHLSPVGSGNDPWSAWSASKSGNWESSEGWGAQPE
                                       10        20        30      

              140       150       160       170       180       190
pF1KB6 GAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKDSESADAGGAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKDSESADAGGAQ
         40        50        60        70        80        90      

              200       210       220       230       240       250
pF1KB6 RGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTF
        100       110       120       130       140       150      

              260       270       280       290       300       310
pF1KB6 DCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSL
        160       170       180       190       200       210      

              320       330       340       350       360       370
pF1KB6 PDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAE
        220       230       240       250       260       270      

              380       390       400       410       420       430
pF1KB6 RDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGP
        280       290       300       310       320       330      

              440       450       460       470       480       490
pF1KB6 LPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLM
        340       350       360       370       380       390      

              500       510       520       530       540       550
pF1KB6 ECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQA
        400       410       420       430       440       450      

              560       570       580       590     
pF1KB6 EMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
       :::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
        460       470       480       490       500 

>>XP_016867572 (OMIM: 614905) PREDICTED: sorting nexin-8  (412 aa)
 initn: 142 init1:  90 opt: 197  Z-score: 171.3  bits: 41.2 E(85289): 0.0084
Smith-Waterman score: 200; 23.7% identity (52.6% similar) in 359 aa overlap (269-590:39-388)

      240       250       260       270       280       290        
pF1KB6 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
                                     ..::...    . :: .::. :  . : ::
XP_016 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
       10        20        30        40        50        60        

      300       310       320       330       340       350        
pF1KB6 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
        ::   . .:.:: :.. :  ..:::. : . :. ... . :::..::. :.. ::.:  
XP_016 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
       70         80         90       100       110       120      

      360       370         380        390          400       410  
pF1KB6 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
           .  :..:.   ::. .  . .  .   : :..    .  :   .  ..: :  :  
XP_016 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
        130       140       150       160       170       180      

                      420         430              440       450   
pF1KB6 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
               :.. .::  :.:       : :::.        . .. .::..:.. :.   
XP_016 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
        190       200       210       220       230       240      

               460       470       480       490         500       
pF1KB6 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
        ... ::. . ::.. :  . . ..      :  :::    : .  :...  :  .  . 
XP_016 DKAAQQGKQEENDVV-EKLNLFLDLL-----QSYKDLCERHEKGVLHKHQRALHKYSLMK
        250       260        270            280       290       300

       510       520        530         540       550       560    
pF1KB6 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
           .:  . .: ...    :.:. :..  :.:  :  .  : :. : . .:   .   .
XP_016 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
              310       320       330       340       350          

          570       580          590                        
pF1KB6 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM                   
        ..: ....:.: .. ...    ::  ::                        
XP_016 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
     360       370       380       390       400       410  

>>XP_016867573 (OMIM: 614905) PREDICTED: sorting nexin-8  (412 aa)
 initn: 142 init1:  90 opt: 197  Z-score: 171.3  bits: 41.2 E(85289): 0.0084
Smith-Waterman score: 200; 23.7% identity (52.6% similar) in 359 aa overlap (269-590:39-388)

      240       250       260       270       280       290        
pF1KB6 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
                                     ..::...    . :: .::. :  . : ::
XP_016 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
       10        20        30        40        50        60        

      300       310       320       330       340       350        
pF1KB6 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
        ::   . .:.:: :.. :  ..:::. : . :. ... . :::..::. :.. ::.:  
XP_016 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
       70         80         90       100       110       120      

      360       370         380        390          400       410  
pF1KB6 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
           .  :..:.   ::. .  . .  .   : :..    .  :   .  ..: :  :  
XP_016 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
        130       140       150       160       170       180      

                      420         430              440       450   
pF1KB6 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
               :.. .::  :.:       : :::.        . .. .::..:.. :.   
XP_016 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
        190       200       210       220       230       240      

               460       470       480       490         500       
pF1KB6 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
        ... ::. . ::.. :  . . ..      :  :::    : .  :...  :  .  . 
XP_016 DKAAQQGKQEENDVV-EKLNLFLDLL-----QSYKDLCERHEKGVLHKHQRALHKYSLMK
        250       260        270            280       290       300

       510       520        530         540       550       560    
pF1KB6 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
           .:  . .: ...    :.:. :..  :.:  :  .  : :. : . .:   .   .
XP_016 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
              310       320       330       340       350          

          570       580          590                        
pF1KB6 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM                   
        ..: ....:.: .. ...    ::  ::                        
XP_016 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
     360       370       380       390       400       410  

>>XP_011513632 (OMIM: 614905) PREDICTED: sorting nexin-8  (451 aa)
 initn: 142 init1:  90 opt: 197  Z-score: 170.8  bits: 41.2 E(85289): 0.009
Smith-Waterman score: 200; 23.7% identity (52.6% similar) in 359 aa overlap (269-590:78-427)

      240       250       260       270       280       290        
pF1KB6 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
                                     ..::...    . :: .::. :  . : ::
XP_011 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
        50        60        70        80        90       100       

      300       310       320       330       340       350        
pF1KB6 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
        ::   . .:.:: :.. :  ..:::. : . :. ... . :::..::. :.. ::.:  
XP_011 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
       110        120        130       140       150       160     

      360       370         380        390          400       410  
pF1KB6 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
           .  :..:.   ::. .  . .  .   : :..    .  :   .  ..: :  :  
XP_011 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
         170       180       190       200       210       220     

                      420         430              440       450   
pF1KB6 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
               :.. .::  :.:       : :::.        . .. .::..:.. :.   
XP_011 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
         230       240       250       260       270       280     

               460       470       480       490         500       
pF1KB6 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
        ... ::. . ::.. :  . . ..      :  :::    : .  :...  :  .  . 
XP_011 DKAAQQGKQEENDVV-EKLNLFLDLL-----QSYKDLCERHEKGVLHKHQRALHKYSLMK
         290       300        310            320       330         

       510       520        530         540       550       560    
pF1KB6 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
           .:  . .: ...    :.:. :..  :.:  :  .  : :. : . .:   .   .
XP_011 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
     340       350       360       370       380       390         

          570       580          590                        
pF1KB6 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM                   
        ..: ....:.: .. ...    ::  ::                        
XP_011 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
      400       410       420       430       440       450 

>>XP_011513631 (OMIM: 614905) PREDICTED: sorting nexin-8  (457 aa)
 initn: 142 init1:  90 opt: 197  Z-score: 170.7  bits: 41.2 E(85289): 0.0091
Smith-Waterman score: 200; 23.7% identity (52.6% similar) in 359 aa overlap (269-590:84-433)

      240       250       260       270       280       290        
pF1KB6 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
                                     ..::...    . :: .::. :  . : ::
XP_011 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
            60        70        80        90       100       110   

      300       310       320       330       340       350        
pF1KB6 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
        ::   . .:.:: :.. :  ..:::. : . :. ... . :::..::. :.. ::.:  
XP_011 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
           120        130        140       150       160       170 

      360       370         380        390          400       410  
pF1KB6 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
           .  :..:.   ::. .  . .  .   : :..    .  :   .  ..: :  :  
XP_011 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
             180       190       200       210       220       230 

                      420         430              440       450   
pF1KB6 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
               :.. .::  :.:       : :::.        . .. .::..:.. :.   
XP_011 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
             240       250       260       270       280       290 

               460       470       480       490         500       
pF1KB6 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
        ... ::. . ::.. :  . . ..      :  :::    : .  :...  :  .  . 
XP_011 DKAAQQGKQEENDVV-EKLNLFLDLL-----QSYKDLCERHEKGVLHKHQRALHKYSLMK
             300        310            320       330       340     

       510       520        530         540       550       560    
pF1KB6 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
           .:  . .: ...    :.:. :..  :.:  :  .  : :. : . .:   .   .
XP_011 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
         350       360       370       380       390        400    

          570       580          590                        
pF1KB6 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM                   
        ..: ....:.: .. ...    ::  ::                        
XP_011 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
          410       420       430       440       450       

>>NP_037453 (OMIM: 614905) sorting nexin-8 [Homo sapiens  (465 aa)
 initn: 142 init1:  90 opt: 197  Z-score: 170.6  bits: 41.2 E(85289): 0.0092
Smith-Waterman score: 200; 23.7% identity (52.6% similar) in 359 aa overlap (269-590:92-441)

      240       250       260       270       280       290        
pF1KB6 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
                                     ..::...    . :: .::. :  . : ::
NP_037 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
              70        80        90       100       110       120 

      300       310       320       330       340       350        
pF1KB6 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
        ::   . .:.:: :.. :  ..:::. : . :. ... . :::..::. :.. ::.:  
NP_037 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
              130       140        150       160       170         

      360       370         380        390          400       410  
pF1KB6 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
           .  :..:.   ::. .  . .  .   : :..    .  :   .  ..: :  :  
NP_037 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
     180       190       200       210       220       230         

                      420         430              440       450   
pF1KB6 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
               :.. .::  :.:       : :::.        . .. .::..:.. :.   
NP_037 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
     240       250       260       270       280       290         

               460       470       480       490         500       
pF1KB6 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
        ... ::. . ::.. :  . . ..      :  :::    : .  :...  :  .  . 
NP_037 DKAAQQGKQEENDVV-EKLNLFLDLL-----QSYKDLCERHEKGVLHKHQRALHKYSLMK
     300       310        320            330       340       350   

       510       520        530         540       550       560    
pF1KB6 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
           .:  . .: ...    :.:. :..  :.:  :  .  : :. : . .:   .   .
NP_037 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
           360       370       380       390       400        410  

          570       580          590                        
pF1KB6 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM                   
        ..: ....:.: .. ...    ::  ::                        
NP_037 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
            420       430       440       450       460     




595 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:35:02 2016 done: Sat Nov  5 13:35:04 2016
 Total Scan time: 10.360 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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