Result of FASTA (omim) for
pF1KB6143
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6143, 595 aa
1>>>pF1KB6143 595 - 595 aa - 595 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2159+/-0.000472; mu= 10.8470+/- 0.029
mean_var=164.3339+/-36.120, 0's: 0 Z-trim(114.1): 113 B-trim: 1431 in 1/54
Lambda= 0.100049
statistics sampled from 23703 (23825) to 23703 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.279), width: 16
Scan time: 10.360
The best scores are: opt bits E(85289)
NP_057308 (OMIM: 605952) sorting nexin-9 [Homo sap ( 595) 4030 594.6 3.1e-169
XP_005267072 (OMIM: 605952) PREDICTED: sorting nex ( 588) 3990 588.8 1.7e-167
XP_011534188 (OMIM: 605952) PREDICTED: sorting nex ( 501) 3377 500.3 6.5e-141
XP_016867572 (OMIM: 614905) PREDICTED: sorting nex ( 412) 197 41.2 0.0084
XP_016867573 (OMIM: 614905) PREDICTED: sorting nex ( 412) 197 41.2 0.0084
XP_011513632 (OMIM: 614905) PREDICTED: sorting nex ( 451) 197 41.2 0.009
XP_011513631 (OMIM: 614905) PREDICTED: sorting nex ( 457) 197 41.2 0.0091
NP_037453 (OMIM: 614905) sorting nexin-8 [Homo sap ( 465) 197 41.2 0.0092
>>NP_057308 (OMIM: 605952) sorting nexin-9 [Homo sapiens (595 aa)
initn: 4030 init1: 4030 opt: 4030 Z-score: 3159.2 bits: 594.6 E(85289): 3.1e-169
Smith-Waterman score: 4030; 100.0% identity (100.0% similar) in 595 aa overlap (1-595:1-595)
10 20 30 40 50 60
pF1KB6 MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR
490 500 510 520 530 540
550 560 570 580 590
pF1KB6 VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
550 560 570 580 590
>>XP_005267072 (OMIM: 605952) PREDICTED: sorting nexin-9 (588 aa)
initn: 3990 init1: 3990 opt: 3990 Z-score: 3128.1 bits: 588.8 E(85289): 1.7e-167
Smith-Waterman score: 3990; 100.0% identity (100.0% similar) in 588 aa overlap (8-595:1-588)
10 20 30 40 50 60
pF1KB6 MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB6 FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB6 EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB6 QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB6 QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR
480 490 500 510 520 530
550 560 570 580 590
pF1KB6 VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
540 550 560 570 580
>>XP_011534188 (OMIM: 605952) PREDICTED: sorting nexin-9 (501 aa)
initn: 3377 init1: 3377 opt: 3377 Z-score: 2650.8 bits: 500.3 E(85289): 6.5e-141
Smith-Waterman score: 3377; 100.0% identity (100.0% similar) in 495 aa overlap (101-595:7-501)
80 90 100 110 120 130
pF1KB6 GNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWESSEGWGAQPE
::::::::::::::::::::::::::::::
XP_011 MKHLSPVGSGNDPWSAWSASKSGNWESSEGWGAQPE
10 20 30
140 150 160 170 180 190
pF1KB6 GAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKDSESADAGGAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKDSESADAGGAQ
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB6 RGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTF
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB6 DCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSL
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB6 PDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAE
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB6 RDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGP
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB6 LPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLM
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB6 ECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQA
400 410 420 430 440 450
560 570 580 590
pF1KB6 EMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
460 470 480 490 500
>>XP_016867572 (OMIM: 614905) PREDICTED: sorting nexin-8 (412 aa)
initn: 142 init1: 90 opt: 197 Z-score: 171.3 bits: 41.2 E(85289): 0.0084
Smith-Waterman score: 200; 23.7% identity (52.6% similar) in 359 aa overlap (269-590:39-388)
240 250 260 270 280 290
pF1KB6 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
..::... . :: .::. : . : ::
XP_016 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
10 20 30 40 50 60
300 310 320 330 340 350
pF1KB6 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
:: . .:.:: :.. : ..:::. : . :. ... . :::..::. :.. ::.:
XP_016 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
70 80 90 100 110 120
360 370 380 390 400 410
pF1KB6 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
. :..:. ::. . . . . : :.. . : . ..: : :
XP_016 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
130 140 150 160 170 180
420 430 440 450
pF1KB6 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
:.. .:: :.: : :::. . .. .::..:.. :.
XP_016 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
190 200 210 220 230 240
460 470 480 490 500
pF1KB6 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
... ::. . ::.. : . . .. : ::: : . :... : . .
XP_016 DKAAQQGKQEENDVV-EKLNLFLDLL-----QSYKDLCERHEKGVLHKHQRALHKYSLMK
250 260 270 280 290 300
510 520 530 540 550 560
pF1KB6 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
.: . .: ... :.:. :.. :.: : . : :. : . .: . .
XP_016 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
310 320 330 340 350
570 580 590
pF1KB6 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM
..: ....:.: .. ... :: ::
XP_016 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
360 370 380 390 400 410
>>XP_016867573 (OMIM: 614905) PREDICTED: sorting nexin-8 (412 aa)
initn: 142 init1: 90 opt: 197 Z-score: 171.3 bits: 41.2 E(85289): 0.0084
Smith-Waterman score: 200; 23.7% identity (52.6% similar) in 359 aa overlap (269-590:39-388)
240 250 260 270 280 290
pF1KB6 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
..::... . :: .::. : . : ::
XP_016 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
10 20 30 40 50 60
300 310 320 330 340 350
pF1KB6 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
:: . .:.:: :.. : ..:::. : . :. ... . :::..::. :.. ::.:
XP_016 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
70 80 90 100 110 120
360 370 380 390 400 410
pF1KB6 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
. :..:. ::. . . . . : :.. . : . ..: : :
XP_016 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
130 140 150 160 170 180
420 430 440 450
pF1KB6 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
:.. .:: :.: : :::. . .. .::..:.. :.
XP_016 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
190 200 210 220 230 240
460 470 480 490 500
pF1KB6 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
... ::. . ::.. : . . .. : ::: : . :... : . .
XP_016 DKAAQQGKQEENDVV-EKLNLFLDLL-----QSYKDLCERHEKGVLHKHQRALHKYSLMK
250 260 270 280 290 300
510 520 530 540 550 560
pF1KB6 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
.: . .: ... :.:. :.. :.: : . : :. : . .: . .
XP_016 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
310 320 330 340 350
570 580 590
pF1KB6 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM
..: ....:.: .. ... :: ::
XP_016 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
360 370 380 390 400 410
>>XP_011513632 (OMIM: 614905) PREDICTED: sorting nexin-8 (451 aa)
initn: 142 init1: 90 opt: 197 Z-score: 170.8 bits: 41.2 E(85289): 0.009
Smith-Waterman score: 200; 23.7% identity (52.6% similar) in 359 aa overlap (269-590:78-427)
240 250 260 270 280 290
pF1KB6 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
..::... . :: .::. : . : ::
XP_011 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
50 60 70 80 90 100
300 310 320 330 340 350
pF1KB6 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
:: . .:.:: :.. : ..:::. : . :. ... . :::..::. :.. ::.:
XP_011 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
110 120 130 140 150 160
360 370 380 390 400 410
pF1KB6 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
. :..:. ::. . . . . : :.. . : . ..: : :
XP_011 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
170 180 190 200 210 220
420 430 440 450
pF1KB6 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
:.. .:: :.: : :::. . .. .::..:.. :.
XP_011 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
230 240 250 260 270 280
460 470 480 490 500
pF1KB6 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
... ::. . ::.. : . . .. : ::: : . :... : . .
XP_011 DKAAQQGKQEENDVV-EKLNLFLDLL-----QSYKDLCERHEKGVLHKHQRALHKYSLMK
290 300 310 320 330
510 520 530 540 550 560
pF1KB6 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
.: . .: ... :.:. :.. :.: : . : :. : . .: . .
XP_011 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
340 350 360 370 380 390
570 580 590
pF1KB6 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM
..: ....:.: .. ... :: ::
XP_011 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
400 410 420 430 440 450
>>XP_011513631 (OMIM: 614905) PREDICTED: sorting nexin-8 (457 aa)
initn: 142 init1: 90 opt: 197 Z-score: 170.7 bits: 41.2 E(85289): 0.0091
Smith-Waterman score: 200; 23.7% identity (52.6% similar) in 359 aa overlap (269-590:84-433)
240 250 260 270 280 290
pF1KB6 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
..::... . :: .::. : . : ::
XP_011 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
60 70 80 90 100 110
300 310 320 330 340 350
pF1KB6 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
:: . .:.:: :.. : ..:::. : . :. ... . :::..::. :.. ::.:
XP_011 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
120 130 140 150 160 170
360 370 380 390 400 410
pF1KB6 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
. :..:. ::. . . . . : :.. . : . ..: : :
XP_011 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
180 190 200 210 220 230
420 430 440 450
pF1KB6 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
:.. .:: :.: : :::. . .. .::..:.. :.
XP_011 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
240 250 260 270 280 290
460 470 480 490 500
pF1KB6 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
... ::. . ::.. : . . .. : ::: : . :... : . .
XP_011 DKAAQQGKQEENDVV-EKLNLFLDLL-----QSYKDLCERHEKGVLHKHQRALHKYSLMK
300 310 320 330 340
510 520 530 540 550 560
pF1KB6 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
.: . .: ... :.:. :.. :.: : . : :. : . .: . .
XP_011 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
350 360 370 380 390 400
570 580 590
pF1KB6 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM
..: ....:.: .. ... :: ::
XP_011 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
410 420 430 440 450
>>NP_037453 (OMIM: 614905) sorting nexin-8 [Homo sapiens (465 aa)
initn: 142 init1: 90 opt: 197 Z-score: 170.6 bits: 41.2 E(85289): 0.0092
Smith-Waterman score: 200; 23.7% identity (52.6% similar) in 359 aa overlap (269-590:92-441)
240 250 260 270 280 290
pF1KB6 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
..::... . :: .::. : . : ::
NP_037 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
70 80 90 100 110 120
300 310 320 330 340 350
pF1KB6 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
:: . .:.:: :.. : ..:::. : . :. ... . :::..::. :.. ::.:
NP_037 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
130 140 150 160 170
360 370 380 390 400 410
pF1KB6 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
. :..:. ::. . . . . : :.. . : . ..: : :
NP_037 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
180 190 200 210 220 230
420 430 440 450
pF1KB6 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
:.. .:: :.: : :::. . .. .::..:.. :.
NP_037 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
240 250 260 270 280 290
460 470 480 490 500
pF1KB6 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
... ::. . ::.. : . . .. : ::: : . :... : . .
NP_037 DKAAQQGKQEENDVV-EKLNLFLDLL-----QSYKDLCERHEKGVLHKHQRALHKYSLMK
300 310 320 330 340 350
510 520 530 540 550 560
pF1KB6 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
.: . .: ... :.:. :.. :.: : . : :. : . .: . .
NP_037 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
360 370 380 390 400 410
570 580 590
pF1KB6 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM
..: ....:.: .. ... :: ::
NP_037 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
420 430 440 450 460
595 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:35:02 2016 done: Sat Nov 5 13:35:04 2016
Total Scan time: 10.360 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]