Result of FASTA (omim) for
pF1KB5968
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5968, 556 aa
1>>>pF1KB5968 556 - 556 aa - 556 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4979+/-0.000377; mu= 13.6199+/- 0.023
mean_var=106.3847+/-21.710, 0's: 0 Z-trim(115.5): 409 B-trim: 14 in 1/52
Lambda= 0.124347
statistics sampled from 25646 (26058) to 25646 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.306), width: 16
Scan time: 6.480
The best scores are: opt bits E(85289)
NP_599022 (OMIM: 600825) nuclear receptor ROR-alph ( 556) 3807 693.9 3.4e-199
NP_002934 (OMIM: 600825) nuclear receptor ROR-alph ( 548) 3384 618.0 2.3e-176
XP_016877955 (OMIM: 600825) PREDICTED: nuclear rec ( 460) 3131 572.6 9.3e-163
NP_599024 (OMIM: 600825) nuclear receptor ROR-alph ( 468) 3124 571.4 2.3e-162
XP_011520177 (OMIM: 600825) PREDICTED: nuclear rec ( 504) 3124 571.4 2.4e-162
XP_011520179 (OMIM: 600825) PREDICTED: nuclear rec ( 467) 3119 570.5 4.2e-162
XP_011520176 (OMIM: 600825) PREDICTED: nuclear rec ( 525) 3117 570.1 5.9e-162
XP_005254641 (OMIM: 600825) PREDICTED: nuclear rec ( 477) 3113 569.4 9e-162
NP_599023 (OMIM: 600825) nuclear receptor ROR-alph ( 523) 3113 569.4 9.7e-162
XP_011520180 (OMIM: 600825) PREDICTED: nuclear rec ( 386) 2590 475.5 1.3e-133
XP_016877956 (OMIM: 600825) PREDICTED: nuclear rec ( 386) 2590 475.5 1.3e-133
XP_011520181 (OMIM: 600825) PREDICTED: nuclear rec ( 376) 2524 463.7 4.8e-130
NP_008845 (OMIM: 601972) nuclear receptor ROR-beta ( 459) 1967 363.8 6.7e-100
NP_001001523 (OMIM: 602943,616622) nuclear recepto ( 497) 950 181.4 6e-45
NP_005051 (OMIM: 602943,616622) nuclear receptor R ( 518) 950 181.4 6.2e-45
XP_006711547 (OMIM: 602943,616622) PREDICTED: nucl ( 651) 950 181.4 7.4e-45
NP_068370 (OMIM: 602408) nuclear receptor subfamil ( 614) 438 89.6 3.2e-17
XP_006713514 (OMIM: 602304) PREDICTED: nuclear rec ( 448) 428 87.7 8.5e-17
NP_001138897 (OMIM: 602304) nuclear receptor subfa ( 504) 428 87.7 9.4e-17
NP_005117 (OMIM: 602304) nuclear receptor subfamil ( 579) 428 87.8 1e-16
XP_005251928 (OMIM: 184757,612964,612965,613957) P ( 461) 419 86.1 2.7e-16
XP_011516757 (OMIM: 184757,612964,612965,613957) P ( 461) 419 86.1 2.7e-16
NP_004950 (OMIM: 184757,612964,612965,613957) ster ( 461) 419 86.1 2.7e-16
NP_001277195 (OMIM: 180220,615524) retinoic acid r ( 399) 417 85.7 3e-16
NP_001277206 (OMIM: 180220,615524) retinoic acid r ( 402) 417 85.7 3.1e-16
NP_001277229 (OMIM: 180220,615524) retinoic acid r ( 405) 417 85.7 3.1e-16
NP_000956 (OMIM: 180220,615524) retinoic acid rece ( 448) 417 85.7 3.3e-16
NP_001277145 (OMIM: 180220,615524) retinoic acid r ( 455) 417 85.7 3.4e-16
NP_001230659 (OMIM: 180190) retinoic acid receptor ( 382) 415 85.3 3.8e-16
NP_001036193 (OMIM: 180190) retinoic acid receptor ( 443) 415 85.4 4.2e-16
NP_000957 (OMIM: 180190) retinoic acid receptor ga ( 454) 415 85.4 4.3e-16
XP_011523398 (OMIM: 180240,612376) PREDICTED: reti ( 404) 407 83.9 1.1e-15
NP_001019980 (OMIM: 180240,612376) retinoic acid r ( 457) 407 83.9 1.2e-15
NP_001138773 (OMIM: 180240,612376) retinoic acid r ( 462) 407 83.9 1.2e-15
XP_011523397 (OMIM: 180240,612376) PREDICTED: reti ( 462) 407 83.9 1.2e-15
XP_005257611 (OMIM: 180240,612376) PREDICTED: reti ( 462) 407 83.9 1.2e-15
XP_005257610 (OMIM: 180240,612376) PREDICTED: reti ( 462) 407 83.9 1.2e-15
NP_000955 (OMIM: 180240,612376) retinoic acid rece ( 462) 407 83.9 1.2e-15
XP_005257609 (OMIM: 180240,612376) PREDICTED: reti ( 478) 407 83.9 1.2e-15
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 399 82.4 2.7e-15
NP_001317544 (OMIM: 125853,601487,601665,604367,60 ( 250) 396 81.8 2.8e-15
XP_011532146 (OMIM: 125853,601487,601665,604367,60 ( 250) 396 81.8 2.8e-15
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 399 82.5 3.1e-15
XP_011532145 (OMIM: 125853,601487,601665,604367,60 ( 278) 396 81.8 3.1e-15
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 399 82.5 3.2e-15
NP_001027458 (OMIM: 601529) nuclear receptor subfa ( 467) 399 82.5 3.2e-15
NP_001120834 (OMIM: 601529) nuclear receptor subfa ( 483) 399 82.5 3.3e-15
XP_011537019 (OMIM: 601529) PREDICTED: nuclear rec ( 507) 399 82.5 3.5e-15
XP_011537018 (OMIM: 601529) PREDICTED: nuclear rec ( 521) 399 82.5 3.5e-15
XP_006719647 (OMIM: 601529) PREDICTED: nuclear rec ( 557) 399 82.5 3.7e-15
>>NP_599022 (OMIM: 600825) nuclear receptor ROR-alpha is (556 aa)
initn: 3807 init1: 3807 opt: 3807 Z-score: 3697.2 bits: 693.9 E(85289): 3.4e-199
Smith-Waterman score: 3807; 100.0% identity (100.0% similar) in 556 aa overlap (1-556:1-556)
10 20 30 40 50 60
pF1KB5 MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
490 500 510 520 530 540
550
pF1KB5 KELFTSEFEPAMQIDG
::::::::::::::::
NP_599 KELFTSEFEPAMQIDG
550
>>NP_002934 (OMIM: 600825) nuclear receptor ROR-alpha is (548 aa)
initn: 3417 init1: 3117 opt: 3384 Z-score: 3287.2 bits: 618.0 E(85289): 2.3e-176
Smith-Waterman score: 3384; 91.5% identity (94.1% similar) in 556 aa overlap (1-556:1-548)
10 20 30 40 50 60
pF1KB5 MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
::::::::::::::::::::::::::::::::::::::::::::: . . :. : .
NP_002 MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARSSSTCSSLSRL---F
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
:. . . :. . : . .: . . .::::::::::::::::::::::
NP_002 WSQLEHINWDGATAKNFINLREFFS-----FLLPALRKAQIEIIPCKICGDKSSGIHYGV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB5 VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB5 KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
480 490 500 510 520 530
550
pF1KB5 KELFTSEFEPAMQIDG
::::::::::::::::
NP_002 KELFTSEFEPAMQIDG
540
>>XP_016877955 (OMIM: 600825) PREDICTED: nuclear recepto (460 aa)
initn: 3131 init1: 3131 opt: 3131 Z-score: 3043.0 bits: 572.6 E(85289): 9.3e-163
Smith-Waterman score: 3131; 100.0% identity (100.0% similar) in 460 aa overlap (97-556:1-460)
70 80 90 100 110 120
pF1KB5 FVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCEGC
::::::::::::::::::::::::::::::
XP_016 MNAQIEIIPCKICGDKSSGIHYGVITCEGC
10 20 30
130 140 150 160 170 180
pF1KB5 KGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB5 DSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB5 ADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAEL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB5 EHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQY
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB5 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKS
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB5 LGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLAL
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB5 QHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTS
400 410 420 430 440 450
550
pF1KB5 EFEPAMQIDG
::::::::::
XP_016 EFEPAMQIDG
460
>>NP_599024 (OMIM: 600825) nuclear receptor ROR-alpha is (468 aa)
initn: 3124 init1: 3124 opt: 3124 Z-score: 3036.1 bits: 571.4 E(85289): 2.3e-162
Smith-Waterman score: 3124; 99.8% identity (100.0% similar) in 460 aa overlap (97-556:9-468)
70 80 90 100 110 120
pF1KB5 FVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCEGC
:.::::::::::::::::::::::::::::
NP_599 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGC
10 20 30
130 140 150 160 170 180
pF1KB5 KGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 KGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB5 DSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 DSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB5 ADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 ADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAEL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB5 EHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 EHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQY
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB5 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKS
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB5 LGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 LGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLAL
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB5 QHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 QHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTS
400 410 420 430 440 450
550
pF1KB5 EFEPAMQIDG
::::::::::
NP_599 EFEPAMQIDG
460
>>XP_011520177 (OMIM: 600825) PREDICTED: nuclear recepto (504 aa)
initn: 3139 init1: 3113 opt: 3124 Z-score: 3035.6 bits: 571.4 E(85289): 2.4e-162
Smith-Waterman score: 3124; 97.1% identity (97.7% similar) in 476 aa overlap (81-556:30-504)
60 70 80 90 100 110
pF1KB5 GILQILHQCILSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICG
::: . : : ..:::::::::::
XP_011 MADVLLEGAVSSSKWETEAIRTTHAVLLKKPP-GWKSGISVTKKTHTSQIEIIPCKICG
10 20 30 40 50
120 130 140 150 160 170
pF1KB5 DKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVG
60 70 80 90 100 110
180 190 200 210 220 230
pF1KB5 MSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELH
120 130 140 150 160 170
240 250 260 270 280 290
pF1KB5 DDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYC
180 190 200 210 220 230
300 310 320 330 340 350
pF1KB5 SFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQRE
240 250 260 270 280 290
360 370 380 390 400 410
pF1KB5 VMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNN
300 310 320 330 340 350
420 430 440 450 460 470
pF1KB5 TVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQ
360 370 380 390 400 410
480 490 500 510 520 530
pF1KB5 EKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPD
420 430 440 450 460 470
540 550
pF1KB5 IVRLHFPPLYKELFTSEFEPAMQIDG
::::::::::::::::::::::::::
XP_011 IVRLHFPPLYKELFTSEFEPAMQIDG
480 490 500
>>XP_011520179 (OMIM: 600825) PREDICTED: nuclear recepto (467 aa)
initn: 3117 init1: 3117 opt: 3119 Z-score: 3031.3 bits: 570.5 E(85289): 4.2e-162
Smith-Waterman score: 3119; 99.4% identity (99.4% similar) in 462 aa overlap (95-556:6-467)
70 80 90 100 110 120
pF1KB5 DAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCE
: ::::::::::::::::::::::::::
XP_011 MKFREGTAIAQIEIIPCKICGDKSSGIHYGVITCE
10 20 30
130 140 150 160 170 180
pF1KB5 GCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKK
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB5 QRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEG
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB5 SKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMA
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB5 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAI
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB5 QYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVF
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB5 KSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB5 ALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF
400 410 420 430 440 450
550
pF1KB5 TSEFEPAMQIDG
::::::::::::
XP_011 TSEFEPAMQIDG
460
>>XP_011520176 (OMIM: 600825) PREDICTED: nuclear recepto (525 aa)
initn: 3117 init1: 3117 opt: 3117 Z-score: 3028.6 bits: 570.1 E(85289): 5.9e-162
Smith-Waterman score: 3117; 100.0% identity (100.0% similar) in 458 aa overlap (99-556:68-525)
70 80 90 100 110 120
pF1KB5 LTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCEGCKG
::::::::::::::::::::::::::::::
XP_011 RASCPTEWGQKVVRGAFRGALRAEKRPAATAQIEIIPCKICGDKSSGIHYGVITCEGCKG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB5 VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF
460 470 480 490 500 510
550
pF1KB5 EPAMQIDG
::::::::
XP_011 EPAMQIDG
520
>>XP_005254641 (OMIM: 600825) PREDICTED: nuclear recepto (477 aa)
initn: 3113 init1: 3113 opt: 3113 Z-score: 3025.3 bits: 569.4 E(85289): 9e-162
Smith-Waterman score: 3113; 99.8% identity (100.0% similar) in 458 aa overlap (99-556:20-477)
70 80 90 100 110 120
pF1KB5 LTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCEGCKG
.:::::::::::::::::::::::::::::
XP_005 MLTGSQSTFGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKG
10 20 30 40
130 140 150 160 170 180
pF1KB5 FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS
50 60 70 80 90 100
190 200 210 220 230 240
pF1KB5 LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD
110 120 130 140 150 160
250 260 270 280 290 300
pF1KB5 SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB5 LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB5 EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG
290 300 310 320 330 340
430 440 450 460 470 480
pF1KB5 CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH
350 360 370 380 390 400
490 500 510 520 530 540
pF1KB5 VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF
410 420 430 440 450 460
550
pF1KB5 EPAMQIDG
::::::::
XP_005 EPAMQIDG
470
>>NP_599023 (OMIM: 600825) nuclear receptor ROR-alpha is (523 aa)
initn: 3113 init1: 3113 opt: 3113 Z-score: 3024.7 bits: 569.4 E(85289): 9.7e-162
Smith-Waterman score: 3113; 99.8% identity (100.0% similar) in 458 aa overlap (99-556:66-523)
70 80 90 100 110 120
pF1KB5 LTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCEGCKG
.:::::::::::::::::::::::::::::
NP_599 ARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB5 VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF
460 470 480 490 500 510
550
pF1KB5 EPAMQIDG
::::::::
NP_599 EPAMQIDG
520
>>XP_011520180 (OMIM: 600825) PREDICTED: nuclear recepto (386 aa)
initn: 2590 init1: 2590 opt: 2590 Z-score: 2519.6 bits: 475.5 E(85289): 1.3e-133
Smith-Waterman score: 2590; 100.0% identity (100.0% similar) in 386 aa overlap (171-556:1-386)
150 160 170 180 190 200
pF1KB5 SCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQ
::::::::::::::::::::::::::::::
XP_011 MSRDAVKFGRMSKKQRDSLYAEVQKHRMQQ
10 20 30
210 220 230 240 250 260
pF1KB5 QQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQP
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB5 SPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLET
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB5 CQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMEL
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB5 CQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFG
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB5 KSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGIL
280 290 300 310 320 330
510 520 530 540 550
pF1KB5 TKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
340 350 360 370 380
556 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:38:43 2016 done: Tue Nov 8 17:38:44 2016
Total Scan time: 6.480 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]