Result of FASTA (omim) for
pF1KB5960
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5960, 551 aa
1>>>pF1KB5960 551 - 551 aa - 551 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.7773+/-0.000437; mu= -24.0844+/- 0.027
mean_var=639.4099+/-131.486, 0's: 0 Z-trim(124.9): 68 B-trim: 0 in 0/61
Lambda= 0.050721
statistics sampled from 47444 (47536) to 47444 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.817), E-opt: 0.2 (0.557), width: 16
Scan time: 11.630
The best scores are: opt bits E(85289)
XP_011525183 (OMIM: 607262) PREDICTED: epsin-1 iso ( 551) 3813 293.8 9.1e-79
XP_016882214 (OMIM: 607262) PREDICTED: epsin-1 iso ( 611) 3813 293.9 9.8e-79
NP_001123543 (OMIM: 607262) epsin-1 isoform a [Hom ( 662) 3813 293.9 1e-78
NP_037465 (OMIM: 607262) epsin-1 isoform c [Homo s ( 550) 3796 292.6 2.2e-78
XP_016882211 (OMIM: 607262) PREDICTED: epsin-1 iso ( 550) 3796 292.6 2.2e-78
XP_005258886 (OMIM: 607262) PREDICTED: epsin-1 iso ( 576) 2609 205.8 3.1e-52
NP_001123544 (OMIM: 607262) epsin-1 isoform b [Hom ( 576) 2609 205.8 3.1e-52
XP_016882212 (OMIM: 607262) PREDICTED: epsin-1 iso ( 636) 2609 205.8 3.4e-52
XP_016882213 (OMIM: 607262) PREDICTED: epsin-1 iso ( 636) 2609 205.8 3.4e-52
NP_001308192 (OMIM: 607262) epsin-1 isoform d [Hom ( 575) 1698 139.1 3.6e-32
XP_011525182 (OMIM: 607262) PREDICTED: epsin-1 iso ( 575) 1698 139.1 3.6e-32
NP_683723 (OMIM: 607263) epsin-2 isoform a [Homo s ( 584) 1318 111.3 8.6e-24
NP_055779 (OMIM: 607263) epsin-2 isoform b [Homo s ( 641) 939 83.6 2.1e-15
NP_060427 (OMIM: 607264) epsin-3 [Homo sapiens] ( 632) 938 83.5 2.2e-15
XP_016865577 (OMIM: 607265) PREDICTED: clathrin in ( 468) 559 55.7 3.8e-07
XP_016865576 (OMIM: 607265) PREDICTED: clathrin in ( 518) 559 55.7 4.1e-07
XP_011533003 (OMIM: 607265) PREDICTED: clathrin in ( 536) 559 55.7 4.2e-07
NP_055481 (OMIM: 607265) clathrin interactor 1 iso ( 625) 559 55.8 4.8e-07
NP_001182484 (OMIM: 607265) clathrin interactor 1 ( 643) 559 55.8 4.9e-07
NP_001182485 (OMIM: 607265) clathrin interactor 1 ( 625) 544 54.7 1e-06
NP_001096134 (OMIM: 607263) epsin-2 isoform c [Hom ( 356) 406 44.4 0.00073
>>XP_011525183 (OMIM: 607262) PREDICTED: epsin-1 isoform (551 aa)
initn: 3813 init1: 3813 opt: 3813 Z-score: 1535.1 bits: 293.8 E(85289): 9.1e-79
Smith-Waterman score: 3813; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551)
10 20 30 40 50 60
pF1KB5 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG
490 500 510 520 530 540
550
pF1KB5 PPAPNTNPFLL
:::::::::::
XP_011 PPAPNTNPFLL
550
>>XP_016882214 (OMIM: 607262) PREDICTED: epsin-1 isoform (611 aa)
initn: 3813 init1: 3813 opt: 3813 Z-score: 1534.5 bits: 293.9 E(85289): 9.8e-79
Smith-Waterman score: 3813; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:61-611)
10 20 30
pF1KB5 MSTSSLRRQMKNIVHNYSEAEIKVREATSN
::::::::::::::::::::::::::::::
XP_016 CQHLPQPSSGSRPISPRIGALCPLLLQPGTMSTSSLRRQMKNIVHNYSEAEIKVREATSN
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB5 DPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSE
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB5 RVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKT
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB5 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDD
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB5 LRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDP
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB5 WGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSD
340 350 360 370 380 390
340 350 360 370 380 390
pF1KB5 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP
400 410 420 430 440 450
400 410 420 430 440 450
pF1KB5 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL
460 470 480 490 500 510
460 470 480 490 500 510
pF1KB5 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL
520 530 540 550 560 570
520 530 540 550
pF1KB5 SPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
:::::::::::::::::::::::::::::::::::::::::
XP_016 SPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
580 590 600 610
>>NP_001123543 (OMIM: 607262) epsin-1 isoform a [Homo sa (662 aa)
initn: 3813 init1: 3813 opt: 3813 Z-score: 1534.0 bits: 293.9 E(85289): 1e-78
Smith-Waterman score: 3813; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:112-662)
10 20 30
pF1KB5 MSTSSLRRQMKNIVHNYSEAEIKVREATSN
::::::::::::::::::::::::::::::
NP_001 CQHLPQPSSGSRPISPRIGALCPLLLQPGTMSTSSLRRQMKNIVHNYSEAEIKVREATSN
90 100 110 120 130 140
40 50 60 70 80 90
pF1KB5 DPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSE
150 160 170 180 190 200
100 110 120 130 140 150
pF1KB5 RVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKT
210 220 230 240 250 260
160 170 180 190 200 210
pF1KB5 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQEERIRRGDD
270 280 290 300 310 320
220 230 240 250 260 270
pF1KB5 LRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDP
330 340 350 360 370 380
280 290 300 310 320 330
pF1KB5 WGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSD
390 400 410 420 430 440
340 350 360 370 380 390
pF1KB5 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP
450 460 470 480 490 500
400 410 420 430 440 450
pF1KB5 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFL
510 520 530 540 550 560
460 470 480 490 500 510
pF1KB5 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL
570 580 590 600 610 620
520 530 540 550
pF1KB5 SPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
:::::::::::::::::::::::::::::::::::::::::
NP_001 SPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
630 640 650 660
>>NP_037465 (OMIM: 607262) epsin-1 isoform c [Homo sapie (550 aa)
initn: 2542 init1: 2542 opt: 3796 Z-score: 1528.4 bits: 292.6 E(85289): 2.2e-78
Smith-Waterman score: 3796; 99.8% identity (99.8% similar) in 551 aa overlap (1-551:1-550)
10 20 30 40 50 60
pF1KB5 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PSTNGTTA-GGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR
370 380 390 400 410
430 440 450 460 470 480
pF1KB5 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB5 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG
480 490 500 510 520 530
550
pF1KB5 PPAPNTNPFLL
:::::::::::
NP_037 PPAPNTNPFLL
540 550
>>XP_016882211 (OMIM: 607262) PREDICTED: epsin-1 isoform (550 aa)
initn: 2542 init1: 2542 opt: 3796 Z-score: 1528.4 bits: 292.6 E(85289): 2.2e-78
Smith-Waterman score: 3796; 99.8% identity (99.8% similar) in 551 aa overlap (1-551:1-550)
10 20 30 40 50 60
pF1KB5 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGEEELQLQLALAMSKEEADQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTNGTTA-GGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVR
370 380 390 400 410
430 440 450 460 470 480
pF1KB5 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB5 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPG
480 490 500 510 520 530
550
pF1KB5 PPAPNTNPFLL
:::::::::::
XP_016 PPAPNTNPFLL
540 550
>>XP_005258886 (OMIM: 607262) PREDICTED: epsin-1 isoform (576 aa)
initn: 2594 init1: 2594 opt: 2609 Z-score: 1058.7 bits: 205.8 E(85289): 3.1e-52
Smith-Waterman score: 3753; 95.7% identity (95.7% similar) in 576 aa overlap (1-551:1-576)
10 20 30 40 50 60
pF1KB5 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
130 140 150 160 170 180
190 200 210
pF1KB5 SGEEELQLQLALAMSKEEADQ-------------------------EERIRRGDDLRLQM
::::::::::::::::::::: ::::::::::::::
XP_005 SGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQM
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB5 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP
490 500 510 520 530 540
520 530 540 550
pF1KB5 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
::::::::::::::::::::::::::::::::::::
XP_005 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
550 560 570
>>NP_001123544 (OMIM: 607262) epsin-1 isoform b [Homo sa (576 aa)
initn: 2594 init1: 2594 opt: 2609 Z-score: 1058.7 bits: 205.8 E(85289): 3.1e-52
Smith-Waterman score: 3753; 95.7% identity (95.7% similar) in 576 aa overlap (1-551:1-576)
10 20 30 40 50 60
pF1KB5 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
130 140 150 160 170 180
190 200 210
pF1KB5 SGEEELQLQLALAMSKEEADQ-------------------------EERIRRGDDLRLQM
::::::::::::::::::::: ::::::::::::::
NP_001 SGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQM
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB5 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP
490 500 510 520 530 540
520 530 540 550
pF1KB5 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
::::::::::::::::::::::::::::::::::::
NP_001 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
550 560 570
>>XP_016882212 (OMIM: 607262) PREDICTED: epsin-1 isoform (636 aa)
initn: 2594 init1: 2594 opt: 2609 Z-score: 1058.1 bits: 205.8 E(85289): 3.4e-52
Smith-Waterman score: 3753; 95.7% identity (95.7% similar) in 576 aa overlap (1-551:61-636)
10 20 30
pF1KB5 MSTSSLRRQMKNIVHNYSEAEIKVREATSN
::::::::::::::::::::::::::::::
XP_016 CQHLPQPSSGSRPISPRIGALCPLLLQPGTMSTSSLRRQMKNIVHNYSEAEIKVREATSN
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB5 DPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSE
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB5 RVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKT
160 170 180 190 200 210
160 170 180 190 200
pF1KB5 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQ---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQPPSCGPEDD
220 230 240 250 260 270
210 220 230 240
pF1KB5 ----------------EERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPA
::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPA
280 290 300 310 320 330
250 260 270 280 290 300
pF1KB5 PTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPS
340 350 360 370 380 390
310 320 330 340 350 360
pF1KB5 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNG
400 410 420 430 440 450
370 380 390 400 410 420
pF1KB5 TTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAE
460 470 480 490 500 510
430 440 450 460 470 480
pF1KB5 AVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP
520 530 540 550 560 570
490 500 510 520 530 540
pF1KB5 ATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPN
580 590 600 610 620 630
550
pF1KB5 TNPFLL
::::::
XP_016 TNPFLL
>>XP_016882213 (OMIM: 607262) PREDICTED: epsin-1 isoform (636 aa)
initn: 2594 init1: 2594 opt: 2609 Z-score: 1058.1 bits: 205.8 E(85289): 3.4e-52
Smith-Waterman score: 3753; 95.7% identity (95.7% similar) in 576 aa overlap (1-551:61-636)
10 20 30
pF1KB5 MSTSSLRRQMKNIVHNYSEAEIKVREATSN
::::::::::::::::::::::::::::::
XP_016 CQHLPQPSSGSRPISPRIGALCPLLLQPGTMSTSSLRRQMKNIVHNYSEAEIKVREATSN
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB5 DPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSE
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB5 RVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKT
160 170 180 190 200 210
160 170 180 190 200
pF1KB5 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQ---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQPPSCGPEDD
220 230 240 250 260 270
210 220 230 240
pF1KB5 ----------------EERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPA
::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPA
280 290 300 310 320 330
250 260 270 280 290 300
pF1KB5 PTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPS
340 350 360 370 380 390
310 320 330 340 350 360
pF1KB5 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNG
400 410 420 430 440 450
370 380 390 400 410 420
pF1KB5 TTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAE
460 470 480 490 500 510
430 440 450 460 470 480
pF1KB5 AVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGP
520 530 540 550 560 570
490 500 510 520 530 540
pF1KB5 ATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPN
580 590 600 610 620 630
550
pF1KB5 TNPFLL
::::::
XP_016 TNPFLL
>>NP_001308192 (OMIM: 607262) epsin-1 isoform d [Homo sa (575 aa)
initn: 2709 init1: 1337 opt: 1698 Z-score: 698.5 bits: 139.1 E(85289): 3.6e-32
Smith-Waterman score: 3736; 95.5% identity (95.5% similar) in 576 aa overlap (1-551:1-575)
10 20 30 40 50 60
pF1KB5 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQS
130 140 150 160 170 180
190 200 210
pF1KB5 SGEEELQLQLALAMSKEEADQ-------------------------EERIRRGDDLRLQM
::::::::::::::::::::: ::::::::::::::
NP_001 SGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQM
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPV
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSS
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
NP_001 SGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTA-GGFDTEPDEFSDFDRLRTALPTSGSS
370 380 390 400 410
400 410 420 430 440 450
pF1KB5 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAA
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB5 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPP
480 490 500 510 520 530
520 530 540 550
pF1KB5 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
::::::::::::::::::::::::::::::::::::
NP_001 VPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
540 550 560 570
551 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:47:18 2016 done: Sat Nov 5 10:47:19 2016
Total Scan time: 11.630 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]