Result of FASTA (omim) for
pF1KB5957
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5957, 513 aa
1>>>pF1KB5957 513 - 513 aa - 513 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6884+/-0.000428; mu= 13.6298+/- 0.026
mean_var=193.2419+/-41.487, 0's: 0 Z-trim(116.8): 272 B-trim: 1510 in 1/55
Lambda= 0.092262
statistics sampled from 27931 (28338) to 27931 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.332), width: 16
Scan time: 9.000
The best scores are: opt bits E(85289)
NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 3570 488.2 2.4e-137
NP_000234 (OMIM: 134610,249100,608107) pyrin isofo ( 781) 1187 171.3 9.4e-42
XP_016878725 (OMIM: 134610,249100,608107) PREDICTE ( 780) 1174 169.6 3.1e-41
NP_976038 (OMIM: 609315) tripartite motif-containi ( 511) 788 117.9 7e-26
NP_006769 (OMIM: 605701) tripartite motif-containi ( 481) 746 112.3 3.2e-24
NP_660215 (OMIM: 607868) E3 ubiquitin-protein liga ( 468) 735 110.8 8.8e-24
NP_006065 (OMIM: 606559) E3 ubiquitin-protein liga ( 498) 697 105.8 3e-22
NP_001723 (OMIM: 601610) butyrophilin subfamily 1 ( 526) 695 105.6 3.8e-22
XP_005249397 (OMIM: 601610) PREDICTED: butyrophili ( 626) 695 105.7 4.2e-22
XP_011512524 (OMIM: 605701) PREDICTED: tripartite ( 499) 689 104.8 6.4e-22
XP_011512523 (OMIM: 605701) PREDICTED: tripartite ( 499) 689 104.8 6.4e-22
XP_011512525 (OMIM: 605701) PREDICTED: tripartite ( 499) 689 104.8 6.4e-22
XP_011538873 (OMIM: 111620,111750,609017) PREDICTE ( 468) 688 104.6 6.7e-22
NP_001017922 (OMIM: 111620,111750,609017) erythroi ( 475) 688 104.6 6.8e-22
XP_006710376 (OMIM: 111620,111750,609017) PREDICTE ( 475) 688 104.6 6.8e-22
NP_061008 (OMIM: 111620,111750,609017) erythroid m ( 475) 688 104.6 6.8e-22
XP_011538872 (OMIM: 111620,111750,609017) PREDICTE ( 475) 688 104.6 6.8e-22
NP_976042 (OMIM: 609315) tripartite motif-containi ( 329) 683 103.7 8.6e-22
NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 685 104.2 9.5e-22
NP_001186502 (OMIM: 606559) E3 ubiquitin-protein l ( 494) 681 103.7 1.3e-21
NP_477514 (OMIM: 607564) tripartite motif-containi ( 488) 680 103.5 1.4e-21
NP_001003818 (OMIM: 607564) tripartite motif-conta ( 516) 680 103.6 1.5e-21
XP_016865392 (OMIM: 609315) PREDICTED: tripartite ( 303) 676 102.7 1.6e-21
NP_976041 (OMIM: 609315) tripartite motif-containi ( 303) 676 102.7 1.6e-21
NP_976039 (OMIM: 609315) tripartite motif-containi ( 303) 676 102.7 1.6e-21
NP_976040 (OMIM: 609315) tripartite motif-containi ( 303) 676 102.7 1.6e-21
NP_001184168 (OMIM: 613591) butyrophilin subfamily ( 313) 675 102.6 1.7e-21
XP_011512533 (OMIM: 613591) PREDICTED: butyrophili ( 313) 675 102.6 1.7e-21
NP_001184162 (OMIM: 613590) butyrophilin subfamily ( 466) 677 103.1 1.9e-21
NP_008980 (OMIM: 613590) butyrophilin subfamily 2 ( 527) 677 103.2 2e-21
NP_853509 (OMIM: 613591) butyrophilin subfamily 2 ( 407) 675 102.8 2e-21
XP_005248855 (OMIM: 613591) PREDICTED: butyrophili ( 407) 675 102.8 2e-21
XP_016865656 (OMIM: 613591) PREDICTED: butyrophili ( 407) 675 102.8 2e-21
XP_011512531 (OMIM: 613591) PREDICTED: butyrophili ( 461) 675 102.8 2.2e-21
XP_016865655 (OMIM: 613591) PREDICTED: butyrophili ( 461) 675 102.8 2.2e-21
XP_005248854 (OMIM: 613591) PREDICTED: butyrophili ( 523) 675 102.9 2.4e-21
XP_011512530 (OMIM: 613591) PREDICTED: butyrophili ( 523) 675 102.9 2.4e-21
NP_001184166 (OMIM: 613591) butyrophilin subfamily ( 523) 675 102.9 2.4e-21
NP_008926 (OMIM: 613591) butyrophilin subfamily 2 ( 523) 675 102.9 2.4e-21
XP_006715016 (OMIM: 613591) PREDICTED: butyrophili ( 523) 675 102.9 2.4e-21
NP_001128327 (OMIM: 606123) E3 ubiquitin-protein l ( 343) 672 102.3 2.4e-21
XP_005253240 (OMIM: 608487) PREDICTED: tripartite ( 493) 674 102.7 2.5e-21
NP_149023 (OMIM: 608487) tripartite motif-containi ( 493) 674 102.7 2.5e-21
XP_011542512 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 672 102.5 3e-21
XP_011542511 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 672 102.5 3e-21
NP_057186 (OMIM: 606123) E3 ubiquitin-protein liga ( 477) 672 102.5 3e-21
NP_001020111 (OMIM: 606123) E3 ubiquitin-protein l ( 477) 672 102.5 3e-21
XP_006711842 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 672 102.5 3e-21
NP_067629 (OMIM: 605684) tripartite motif-containi ( 488) 672 102.5 3e-21
NP_001003827 (OMIM: 605684) tripartite motif-conta ( 488) 672 102.5 3e-21
>>NP_006501 (OMIM: 602165) zinc finger protein RFP [Homo (513 aa)
initn: 3570 init1: 3570 opt: 3570 Z-score: 2586.9 bits: 488.2 E(85289): 2.4e-137
Smith-Waterman score: 3570; 100.0% identity (100.0% similar) in 513 aa overlap (1-513:1-513)
10 20 30 40 50 60
pF1KB5 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSG
430 440 450 460 470 480
490 500 510
pF1KB5 GKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
:::::::::::::::::::::::::::::::::
NP_006 GKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
490 500 510
>>NP_000234 (OMIM: 134610,249100,608107) pyrin isoform 1 (781 aa)
initn: 761 init1: 619 opt: 1187 Z-score: 870.6 bits: 171.3 E(85289): 9.4e-42
Smith-Waterman score: 1191; 38.6% identity (68.7% similar) in 485 aa overlap (17-494:313-777)
10 20 30 40
pF1KB5 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICC---ACLARC
: : ..:. : .. : : ..
NP_000 PDGGASADLKEGPGNPEHSVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHP
290 300 310 320 330 340
50 60 70 80 90 100
pF1KB5 WGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPL
... . .::.:... : : :. . :. : . :..: . .
NP_000 QASGSRSPGCPRCQDS----HER------------KSPGSLSPQ-P---LPQCKRHLKQV
350 360 370 380
110 120 130 140 150 160
pF1KB5 KL-YCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRA
.: .::. . :::..:. :.::.:: : :.::.. :..::.::.:::... ...:.
NP_000 QLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRS
390 400 410 420 430 440
170 180 190 200 210 220
pF1KB5 QGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQF
::. . .:. :. .... ..::.:. :...:. ..: ::.. . . .. :.
NP_000 YGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRV
450 460 470 480 490 500
230 240 250 260 270 280
pF1KB5 SCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQ
: .:. :..::..:: :. : :::::::: : ::. . .:: : :: ....::... :
NP_000 SQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQ
510 520 530 540 550 560
290 300 310 320 330 340
pF1KB5 KCLFLTESLKQFTEKMQSDME--KIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRY
: :. .: : :.: ..:.:: .. :: :: ..:.: :: .::::.::.::.:..::
NP_000 KSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRL
570 580 590 600 610 620
350 360 370 380 390 400
pF1KB5 SYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTS
. . :::.:.::. ::::: :..::.:::::::::. : .:.:. :. :::..:
NP_000 GNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTL
630 640 650 660 670 680
410 420 430 440 450 460
pF1KB5 APQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFT
.:.::.:.: . .:: : . : : : .. : .:::::.:: .: .:::::: : : .:
NP_000 SPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYT
690 700 710 720 730 740
470 480 490 500 510
pF1KB5 FSHATFCGPVRPYFSL-SYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
:. .: ::..: :: . .:::..::: :::..:
NP_000 FASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
750 760 770 780
>>XP_016878725 (OMIM: 134610,249100,608107) PREDICTED: p (780 aa)
initn: 836 init1: 619 opt: 1174 Z-score: 861.3 bits: 169.6 E(85289): 3.1e-41
Smith-Waterman score: 1178; 38.6% identity (68.5% similar) in 485 aa overlap (17-494:313-776)
10 20 30 40
pF1KB5 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICC---ACLARC
: : ..:. : .. : : ..
XP_016 PDGGASADLKEGPGNPEHSVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHP
290 300 310 320 330 340
50 60 70 80 90 100
pF1KB5 WGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPL
... . .::.:... : : :. . :. : . :..: . .
XP_016 QASGSRSPGCPRCQDS----HER------------KSPGSLSPQ-P---LPQCKRHLKQV
350 360 370 380
110 120 130 140 150 160
pF1KB5 KL-YCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRA
.: .::. . :::..:. :.::.:: : :.::.. : .::.::.:::... ...:.
XP_016 QLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHK-KIQKQLEHLKKLRKSGEEQRS
390 400 410 420 430 440
170 180 190 200 210 220
pF1KB5 QGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQF
::. . .:. :. .... ..::.:. :...:. ..: ::.. . . .. :.
XP_016 YGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRV
450 460 470 480 490 500
230 240 250 260 270 280
pF1KB5 SCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQ
: .:. :..::..:: :. : :::::::: : ::. . .:: : :: ....::... :
XP_016 SQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQ
510 520 530 540 550 560
290 300 310 320 330 340
pF1KB5 KCLFLTESLKQFTEKMQSDME--KIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRY
: :. .: : :.: ..:.:: .. :: :: ..:.: :: .::::.::.::.:..::
XP_016 KSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRL
570 580 590 600 610 620
350 360 370 380 390 400
pF1KB5 SYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTS
. . :::.:.::. ::::: :..::.:::::::::. : .:.:. :. :::..:
XP_016 GNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTL
630 640 650 660 670 680
410 420 430 440 450 460
pF1KB5 APQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFT
.:.::.:.: . .:: : . : : : .. : .:::::.:: .: .:::::: : : .:
XP_016 SPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYT
690 700 710 720 730 740
470 480 490 500 510
pF1KB5 FSHATFCGPVRPYFSL-SYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
:. .: ::..: :: . .:::..::: :::..:
XP_016 FASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
750 760 770 780
>>NP_976038 (OMIM: 609315) tripartite motif-containing p (511 aa)
initn: 1151 init1: 488 opt: 788 Z-score: 585.6 bits: 117.9 E(85289): 7e-26
Smith-Waterman score: 1149; 40.3% identity (65.3% similar) in 501 aa overlap (5-480:18-504)
10 20 30 40
pF1KB5 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCW---
..: :: :.:: .::. : ::. ..:::..: ::..:::
NP_976 MAAVGPRTGPGTGAEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERP
10 20 30 40 50 60
50 60 70 80 90
pF1KB5 -----GTAETN----VSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGV
:.: . :::::: ..::::.:: :. :.. : :.. :: :
NP_976 GAGSVGAATRAPPFPLPCPQCREPARPSQLRPNRQLAAVATLLR--RFSLPAAAPGEHGS
70 80 90 100 110
100 110 120 130 140
pF1KB5 -----------CEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQ
: .: ::.::::..: :::::::.:::: :.::::.:::. :: ..
NP_976 QAAAARAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLE
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB5 NQLDHLKR-VKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLAR
..: ::. ..: . : .. .... :::. :.::. ::. : : :.: :::.:
NP_976 SRLRVLKKELEDCEVFRSTEKKESK-ELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGR
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB5 LEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRI
::::. . .. : ..:.. .:..::.: .:..: :.: ..::.. .:::: .
NP_976 LEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPG
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB5 PEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPD
:.: . ....:. . : . : ::.: : .....:: .. :..:::::
NP_976 PKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEK--------VELTLDPD
300 310 320 330 340
330 340 350 360 370 380
pF1KB5 TAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKW
:: : :::: .:. :: . ::::..: ::. ::.: : .:::.::::::.: :
NP_976 TANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGW
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB5 TIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTP-LQRVGIFLDY
..:: ..:: ::: . .:..: ::..: : .:::.::: . :: :.:: . ::
NP_976 AFGVARESVRRKGLTPFTPEEGVWALQL-NGGQYWAVTSPERS-PLSCGHLSRVRVALDL
410 420 430 440 450 460
450 460 470 480 490 500
pF1KB5 DAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHV
..: :::: : . : .:: ...: : : ::. .:
NP_976 EVGAVSFYAVEDMRHLYTF-RVNFQERVFPLFSVCSTGTYLRIWP
470 480 490 500 510
510
pF1KB5 GNHGHSMETSP
>>NP_006769 (OMIM: 605701) tripartite motif-containing p (481 aa)
initn: 896 init1: 416 opt: 746 Z-score: 555.7 bits: 112.3 E(85289): 3.2e-24
Smith-Waterman score: 963; 34.7% identity (64.1% similar) in 487 aa overlap (1-476:1-470)
10 20 30 40 50
pF1KB5 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLAR-CWGTA---ETNVSCPQC
:::.. . : .:..::.: . ::. .:::::.: :::.: : . : . .:: :
NP_006 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 RETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICV
.: : .::: .::::.. ...:. : : : ::..: : . ..::.:.: .::
NP_006 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLG-EEDVCQEHGEKIYFFCEDDEMQLCV
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 VCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQ
:: .. :: :.. ::.:. ..:::.. : :.. .. .. ... .. ::. ..
NP_006 VCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 MEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQL
.:.... :: .: . :.:.. :::.:: : : . . . .: ..:.:: .:
NP_006 TKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEEL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 EEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTE
:::...:.:::: :: .:: : : . .: . :.: ..:. : :. : : . .:.: :
NP_006 EEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 KMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNL
:. ... . ..:::.:..:.:.::.. .....:: :. ::::.::.
NP_006 KLCFELD---------YEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 FPCVLGSPCFIAGRHYWEVEVGDKAKW---TIGVCEDSVCRKGGVTSAPQNGFWAVSLWY
:::. . .::: : : . : :. :.:: ..: ::: . :..: ::: :
NP_006 ATCVLAHTGITGGRHTWVVSI-DLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRL--
360 370 380 390 400
420 430 440 450 460
pF1KB5 GKEYWALTSPMTALPLRTPLQ----RVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGP
:...: . ..: : :. .: . :::..: :.: :.. : .::. :.:
NP_006 ---AWGFVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFT-ASFTRK
410 420 430 440 450 460
470 480 490 500 510
pF1KB5 VRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
: :.:.:
NP_006 VIPFFGLWGRGSSFSLSS
470 480
>>NP_660215 (OMIM: 607868) E3 ubiquitin-protein ligase T (468 aa)
initn: 1261 init1: 401 opt: 735 Z-score: 547.9 bits: 110.8 E(85289): 8.8e-24
Smith-Waterman score: 1238; 40.6% identity (67.8% similar) in 500 aa overlap (1-497:1-462)
10 20 30 40 50 60
pF1KB5 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF
::. ... ::.:.:: .::.::..:.: :::::.: :. :::: : .::.:::
NP_660 MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR
:::..:::: ::........:. : .: . ::: ::::: .: .. .:..:.:
NP_660 PQRNLRPNRPLAKMAEMARRLH---PPSPVPQ-GVCPAHREPLAAFCGDELRLLCAACER
70 80 90 100 110
130 140 150 160 170 180
pF1KB5 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE
: :: .: : ::..:.: .: .....:.::.. . .::.... . .... .:.
NP_660 SGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ
... :::.: . : :.: .:: :::: .: . . . .... . .::. :::.:: .
NP_660 NVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS
: :. ::::: :.: :.. ... : ..: .:. .. . :.:.:..:
NP_660 QLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPG-----LVETLRRFRG----
240 250 260 270 280
310 320 330 340 350 360
pF1KB5 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV
::::::::: : ::::.. :.:. . :.: :::.::::. :::
NP_660 ----------------DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCV
290 300 310 320 330
370 380 390 400 410
pF1KB5 LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRK-GGVTSAPQNGFWAVSLWYGKEYWA
::. : .:::::::::::...:..:::...: :: : :: :::: . .. :. :
NP_660 LGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEKGELSAG-NGFW-ILVFLGSYY--
340 350 360 370 380
420 430 440 450 460 470
pF1KB5 LTSPMTAL-PLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFS-LS
.: :: ::: : .::::::::.::..:::..:. : : . : : .:: :: ::
NP_660 -NSSERALAPLRDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLS
390 400 410 420 430 440
480 490 500 510
pF1KB5 YSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
.: .:. :: .: .:
NP_660 ----SSPTPMTICRPKGGSGDTLAPQ
450 460
>>NP_006065 (OMIM: 606559) E3 ubiquitin-protein ligase T (498 aa)
initn: 822 init1: 327 opt: 697 Z-score: 520.3 bits: 105.8 E(85289): 3e-22
Smith-Waterman score: 852; 30.9% identity (60.5% similar) in 517 aa overlap (5-493:4-497)
10 20 30 40 50
pF1KB5 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACL-ARCWGT---AETNVSCPQC
:: ...:.:::.::. ..::. :::::..: ::. :. . .. . ::: :
NP_006 MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVC
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 RETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICV
. : ..::::::::... ::... :. : . :::.: . :...:.:: ::
NP_006 QTRFQPGNLRPNRHLANIVERVKEVKMS-PQ-EGQKRDVCEHHGKKLQIFCKEDGKVICW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 VCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQ
::. :.::.::... ..:.:. .:..: :..: . . .. . . .: :. . :
NP_006 VCELSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 MEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQL
.::.::. :... : ..: : : .::: .. . ... .: :. . . :.::..:
NP_006 IERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 EEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTE
... . . :.:::. :...:.: . . : ....:. : .: . .:. .
NP_006 QRRLRGSSVEMLQDVIDVMKRSESWTLKK----PKSVSKKL-----KSVFRVPDLSGM--
240 250 260 270 280
300 310 320 330 340 350
pF1KB5 KMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNL
.. ..:: ..: : ::: :.: .: .. .: . :::. .:: :.
NP_006 -----LQVLKELTDVQYYWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSA
290 300 310 320 330 340
360 370 380 390 400
pF1KB5 FPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCE--DSVCRKGGVTSA-------------
: :.: : .:..::::.:. : : .:: .:. .. . :
NP_006 FG-VFGCQYFSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSR
350 360 370 380 390 400
410 420 430 440 450
pF1KB5 --PQNGFWAVSLWYGKEYWALTSPMTALP------LRTPLQRVGIFLDYDAGEVSFYNVT
:: :.:...: :: :. . .. : . .: :.:.::::.:: :::.:::
NP_006 YRPQYGYWVIGLQNTCEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVT
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB5 ER-CHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETS
.. . :: : :. :::. . .:. .:: :
NP_006 NHGALIYKFSGCRFSRPAYPYFN----PWNCLVPMTVCPPSS
470 480 490
pF1KB5 P
>>NP_001723 (OMIM: 601610) butyrophilin subfamily 1 memb (526 aa)
initn: 675 init1: 393 opt: 695 Z-score: 518.6 bits: 105.6 E(85289): 3.8e-22
Smith-Waterman score: 695; 50.7% identity (75.6% similar) in 209 aa overlap (289-497:278-478)
260 270 280 290 300 310
pF1KB5 ERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDV
: ..:. : . .:... ..: :..:::
NP_001 VAVAVILMVLGLLTIGSIFFTWRLYNERPRERRNEFSSK-ERLLEELK-WKKATLHAVDV
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB5 TLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVG
:::::::.: :.: .. ..:: .: ::.. :::. .::::: : .::::::::::
NP_001 TLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKTERFDSWPCVLGRETFTSGRHYWEVEVG
310 320 330 340 350 360
380 390 400 410 420 430
pF1KB5 DKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGI
:.. :.::::...: .:: .:.:::::: : ::. ::::: : ::: : .::::
NP_001 DRTDWAIGVCRENVMKKGFDPMTPENGFWAVEL-YGNGYWALTPLRTPLPLAGPPRRVGI
370 380 390 400 410 420
440 450 460 470 480 490
pF1KB5 FLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGF
::::..:..::::... .:::..:: ::.::.: : .:.::. :: :::.. ::
NP_001 FLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFFCL-WSSGKK--PLTICPIA--DGP
430 440 450 460 470
500 510
pF1KB5 SGHVGNHGHSMETSP
NP_001 ERVTVIANAQDLSKEIPLSPMGEDSAPRDADTLHSKLIPTQPSQGAP
480 490 500 510 520
>>XP_005249397 (OMIM: 601610) PREDICTED: butyrophilin su (626 aa)
initn: 675 init1: 393 opt: 695 Z-score: 517.8 bits: 105.7 E(85289): 4.2e-22
Smith-Waterman score: 695; 50.7% identity (75.6% similar) in 209 aa overlap (289-497:378-578)
260 270 280 290 300 310
pF1KB5 ERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDV
: ..:. : . .:... ..: :..:::
XP_005 VAVAVILMVLGLLTIGSIFFTWRLYNERPRERRNEFSSK-ERLLEELK-WKKATLHAVDV
350 360 370 380 390 400
320 330 340 350 360 370
pF1KB5 TLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVG
:::::::.: :.: .. ..:: .: ::.. :::. .::::: : .::::::::::
XP_005 TLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKTERFDSWPCVLGRETFTSGRHYWEVEVG
410 420 430 440 450 460
380 390 400 410 420 430
pF1KB5 DKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGI
:.. :.::::...: .:: .:.:::::: : ::. ::::: : ::: : .::::
XP_005 DRTDWAIGVCRENVMKKGFDPMTPENGFWAVEL-YGNGYWALTPLRTPLPLAGPPRRVGI
470 480 490 500 510 520
440 450 460 470 480 490
pF1KB5 FLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGF
::::..:..::::... .:::..:: ::.::.: : .:.::. :: :::.. ::
XP_005 FLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFFCL-WSSGKK--PLTICPIA--DGP
530 540 550 560 570
500 510
pF1KB5 SGHVGNHGHSMETSP
XP_005 ERVTVIANAQDLSKEIPLSPMGEDSAPRDADTLHSKLIPTQPSQGAP
580 590 600 610 620
>>XP_011512524 (OMIM: 605701) PREDICTED: tripartite moti (499 aa)
initn: 839 init1: 416 opt: 689 Z-score: 514.5 bits: 104.8 E(85289): 6.4e-22
Smith-Waterman score: 906; 34.8% identity (63.9% similar) in 463 aa overlap (25-476:43-488)
10 20 30 40 50
pF1KB5 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLAR-CWGTA---ETN
::. .:::::.: :::.: : . : .
XP_011 TQSPTCPQKNISSDSGQLTYHHFPSTGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEES
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB5 VSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEED
.:: :.: : .::: .::::.. ...:. : : : ::..: : . ..::.:
XP_011 PTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLG-EEDVCQEHGEKIYFFCEDD
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB5 QMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAE
.: .:::: .. :: :.. ::.:. ..:::.. : :.. .. .. ... ..
XP_011 EMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQV
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB5 LLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLS
::. .. .:.... :: .: . :.:.. :::.:: : : . . . .: ..:
XP_011 LLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFS
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB5 SLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTES
.:: .::::...:.:::: :: .:: : : . .: . :.: ..:. : :. : : .
XP_011 ALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQRE
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB5 LKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDN
.:.: ::. ... . ..:::.:..:.:.::.. .....:: :. :::
XP_011 MKMFLEKLCFELD---------YEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDN
320 330 340 350 360
360 370 380 390 400
pF1KB5 PERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKW---TIGVCEDSVCRKGGVTSAPQNGFW
:.::. :::. . .::: : : . : :. :.:: ..: ::: . :..: :
XP_011 PQRFDRATCVLAHTGITGGRHTWVVSI-DLAHGGSCTVGVVSEDVQRKGELRLRPEEGVW
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB5 AVSLWYGKEYWALTSPMTALPLRTPLQ----RVGIFLDYDAGEVSFYNVTERCHTFTFSH
:: : :...: . ..: : :. .: . :::..: :.: :.. : .::.
XP_011 AVRL-----AWGFVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFT-
430 440 450 460 470
470 480 490 500 510
pF1KB5 ATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
:.: : :.:.:
XP_011 ASFTRKVIPFFGLWGRGSSFSLSS
480 490
513 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:45:58 2016 done: Sat Nov 5 10:45:59 2016
Total Scan time: 9.000 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]