Result of FASTA (omim) for
pF1KB5884
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5884, 496 aa
1>>>pF1KB5884 496 - 496 aa - 496 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.5445+/-0.00039; mu= -0.6945+/- 0.024
mean_var=284.8863+/-60.524, 0's: 0 Z-trim(121.9): 16 B-trim: 1141 in 2/55
Lambda= 0.075987
statistics sampled from 39120 (39144) to 39120 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.459), width: 16
Scan time: 11.690
The best scores are: opt bits E(85289)
NP_542779 (OMIM: 608527) sialidase-4 isoform 1 [Ho ( 496) 3527 400.1 7.6e-111
NP_001161071 (OMIM: 608527) sialidase-4 isoform 2 ( 497) 3515 398.8 1.9e-110
NP_001161072 (OMIM: 608527) sialidase-4 isoform 3 ( 484) 3443 390.9 4.4e-108
NP_001161074 (OMIM: 608527) sialidase-4 isoform 3 ( 484) 3443 390.9 4.4e-108
NP_001161073 (OMIM: 608527) sialidase-4 isoform 3 ( 484) 3443 390.9 4.4e-108
NP_006647 (OMIM: 604617) sialidase-3 [Homo sapiens ( 461) 957 118.3 4.7e-26
NP_005374 (OMIM: 605528) sialidase-2 [Homo sapiens ( 380) 809 102.0 3.1e-21
>>NP_542779 (OMIM: 608527) sialidase-4 isoform 1 [Homo s (496 aa)
initn: 3527 init1: 3527 opt: 3527 Z-score: 2111.0 bits: 400.1 E(85289): 7.6e-111
Smith-Waterman score: 3527; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KB5 MMSSAAFPRWLSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MMSSAAFPRWLSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP
430 440 450 460 470 480
490
pF1KB5 KPPNLGDKPRGCCWPS
::::::::::::::::
NP_542 KPPNLGDKPRGCCWPS
490
>>NP_001161071 (OMIM: 608527) sialidase-4 isoform 2 [Hom (497 aa)
initn: 3513 init1: 3448 opt: 3515 Z-score: 2103.9 bits: 398.8 E(85289): 1.9e-110
Smith-Waterman score: 3515; 99.8% identity (99.8% similar) in 497 aa overlap (1-496:1-497)
10 20 30 40 50
pF1KB5 MMSSAAFPRWL-SMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPD
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMSSAAFPRWLQSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 DSHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 HTPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 PSGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 VDGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 PNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 GPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 EPWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPAS
430 440 450 460 470 480
480 490
pF1KB5 PKPPNLGDKPRGCCWPS
:::::::::::::::::
NP_001 PKPPNLGDKPRGCCWPS
490
>>NP_001161072 (OMIM: 608527) sialidase-4 isoform 3 [Hom (484 aa)
initn: 3443 init1: 3443 opt: 3443 Z-score: 2061.4 bits: 390.9 E(85289): 4.4e-108
Smith-Waterman score: 3443; 100.0% identity (100.0% similar) in 484 aa overlap (13-496:1-484)
10 20 30 40 50 60
pF1KB5 MMSSAAFPRWLSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD
10 20 30 40
70 80 90 100 110 120
pF1KB5 SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB5 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP
410 420 430 440 450 460
490
pF1KB5 KPPNLGDKPRGCCWPS
::::::::::::::::
NP_001 KPPNLGDKPRGCCWPS
470 480
>>NP_001161074 (OMIM: 608527) sialidase-4 isoform 3 [Hom (484 aa)
initn: 3443 init1: 3443 opt: 3443 Z-score: 2061.4 bits: 390.9 E(85289): 4.4e-108
Smith-Waterman score: 3443; 100.0% identity (100.0% similar) in 484 aa overlap (13-496:1-484)
10 20 30 40 50 60
pF1KB5 MMSSAAFPRWLSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD
10 20 30 40
70 80 90 100 110 120
pF1KB5 SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB5 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP
410 420 430 440 450 460
490
pF1KB5 KPPNLGDKPRGCCWPS
::::::::::::::::
NP_001 KPPNLGDKPRGCCWPS
470 480
>>NP_001161073 (OMIM: 608527) sialidase-4 isoform 3 [Hom (484 aa)
initn: 3443 init1: 3443 opt: 3443 Z-score: 2061.4 bits: 390.9 E(85289): 4.4e-108
Smith-Waterman score: 3443; 100.0% identity (100.0% similar) in 484 aa overlap (13-496:1-484)
10 20 30 40 50 60
pF1KB5 MMSSAAFPRWLSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDD
10 20 30 40
70 80 90 100 110 120
pF1KB5 SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTE
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB5 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASP
410 420 430 440 450 460
490
pF1KB5 KPPNLGDKPRGCCWPS
::::::::::::::::
NP_001 KPPNLGDKPRGCCWPS
470 480
>>NP_006647 (OMIM: 604617) sialidase-3 [Homo sapiens] (461 aa)
initn: 1160 init1: 657 opt: 957 Z-score: 588.8 bits: 118.3 E(85289): 4.7e-26
Smith-Waterman score: 1154; 42.6% identity (61.2% similar) in 469 aa overlap (24-489:46-455)
10 20 30 40 50
pF1KB5 MMSSAAFPRWLSMGVPRTPSRTVLFERERT-GLTYRVPSLLPVPPGPTLLAFV
::..: :.:::.:.:: .:: :.:::.
NP_006 ASSSAPTETEEPGSSAEVMEEVTTCSFNSPLFRQEDDRGITYRIPALLYIPPTHTFLAFA
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB5 EQRLSPDDSHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFL
:.: . : : .:::::: : :.:: :. : :.: ::.:::::: . .: :::
NP_006 EKRSTRRDEDALHLVLRRGLRIGQLVQWGPLKPLMEATLPGHRTMNPCPVWEQKSGCVFL
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB5 FFIAVLGHTPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVG
::: : ::. : ::..:::::::: . :.::: ::. .::::::.::. .. :::::::
NP_006 FFICVRGHVTERQQIVSGRNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVG
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB5 PGHGVQLPSGRLLVPAYTYRVDRRE-CFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLR
::::.:: ::::..::::: . :: :.: :::. .:::: : ::. : :. .
NP_006 PGHGIQLQSGRLVIPAYTYYIPSWFFCFQLPCKTRPHSLMIYSDDLGVTWHHGRLIRPMV
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB5 SGECQLAAVDGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGS
. ::..: : : . :::.::.: :..:::::.: .: .: : :::::
NP_006 TVECEVAEVTGRAGHPVLYCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGS
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB5 IVGF-PAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQ
.:.: : :.: .:.: :.
NP_006 VVSFRPLEIPHRCQDSS---------------------------------------SK--
320 330
360 370 380 390 400 410
pF1KB5 PRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQ
:.: :: : : . : : .:::::::..:. :. .:: :.:
NP_006 ---DAPTIQQSSPGSS---------LRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQ
340 350 360 370 380
420 430 440 450 460 470
pF1KB5 SPLDPRSWTEPWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLR
.::. :..::... :: ::::::.. : :: :.::.: :.. ..:.: :. :
NP_006 TPLEAACWSRPWILHCGPCGYSDLAAL---EEEGL-FGCLFECGTKQECEQIAFRLFTHR
390 400 410 420 430
480 490
pF1KB5 EVLENVPASPKPPNLGDKPRGCCWPS
:.: .. .. : : .:
NP_006 EILSHLQGDCTSP--GRNPSQFKSN
440 450 460
>>NP_005374 (OMIM: 605528) sialidase-2 [Homo sapiens] (380 aa)
initn: 966 init1: 363 opt: 809 Z-score: 502.2 bits: 102.0 E(85289): 3.1e-21
Smith-Waterman score: 880; 38.8% identity (56.6% similar) in 454 aa overlap (34-482:20-379)
10 20 30 40 50 60
pF1KB5 SAAFPRWLSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHA
::.:.:: .: .::::.::: : : ::
NP_005 MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHA
10 20 30 40
70 80 90 100 110 120
pF1KB5 HRLVLRRGTLAGGS--VRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHT
. .::::: . . :.: : .:.. : : ::::::::..:: :::.::::::. :..
NP_005 ELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 PEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPS
: :. : :..::: :.: : : .:.: ::::. ::: : ..:.:::::::: .:: .
NP_005 TEQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHD
110 120 130 140 150 160
190 200 210 220 230
pF1KB5 -GR-LLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAA
.: :.::::.:: . : : : .: : : :::::: : .: . . :::.:
NP_005 RARSLVVPAYAYRK-----LHPIQRPIPSAFCFLSHDHGRTWARGHFVAQ-DTLECQVAE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 VDGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETA-WGCQGSIVGFPAP
:. :. . :::: : .:::: ::..: .: .. : .: : :::::...::.:
NP_005 VETGEQ-RVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSP
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 APNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQ
:. ::::: :
NP_005 -----RS-----GPGSPAQ-----------------------------------------
290
360 370 380 390 400 410
pF1KB5 PGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSW
::::.::. : .: :. : :..:
NP_005 ------------------------------WLLYTHPTHSWQRADLGAYLNPRPPAPEAW
300 310 320
420 430 440 450 460 470
pF1KB5 TEPWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPA
.:: .. .: .:::: :.: .:.:. .:.::::.. .:.:: : :.:.... ::
NP_005 SEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEAN---DYEEIVFLMFTLKQAF---PA
330 340 350 360 370
480 490
pF1KB5 SPKPPNLGDKPRGCCWPS
:
NP_005 EYLPQ
380
496 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:06:07 2016 done: Sat Nov 5 21:06:08 2016
Total Scan time: 11.690 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]