Result of FASTA (ccds) for
pF1KB5808
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5808, 454 aa
1>>>pF1KB5808 454 - 454 aa - 454 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3916+/-0.000699; mu= 10.1566+/- 0.043
mean_var=143.3517+/-28.637, 0's: 0 Z-trim(115.3): 123 B-trim: 16 in 1/54
Lambda= 0.107121
statistics sampled from 15733 (15857) to 15733 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.797), E-opt: 0.2 (0.487), width: 16
Scan time: 3.290
The best scores are: opt bits E(32554)
CCDS8850.1 RARG gene_id:5916|Hs108|chr12 ( 454) 3103 490.5 1.5e-138
CCDS41790.1 RARG gene_id:5916|Hs108|chr12 ( 443) 2700 428.2 8.1e-120
CCDS58236.1 RARG gene_id:5916|Hs108|chr12 ( 382) 2618 415.5 4.7e-116
CCDS58237.1 RARG gene_id:5916|Hs108|chr12 ( 432) 2325 370.3 2.2e-102
CCDS2642.1 RARB gene_id:5915|Hs108|chr3 ( 448) 2199 350.8 1.7e-96
CCDS11366.1 RARA gene_id:5914|Hs108|chr17 ( 462) 2167 345.9 5.2e-95
CCDS42317.1 RARA gene_id:5914|Hs108|chr17 ( 457) 2124 339.2 5.2e-93
CCDS46775.1 RARB gene_id:5915|Hs108|chr3 ( 336) 1777 285.5 5.7e-77
CCDS45671.1 RARA gene_id:5914|Hs108|chr17 ( 365) 1460 236.5 3.4e-62
CCDS35172.1 RXRA gene_id:6256|Hs108|chr9 ( 462) 739 125.2 1.4e-28
CCDS8818.1 NR4A1 gene_id:3164|Hs108|chr12 ( 598) 725 123.1 7.8e-28
CCDS4768.1 RXRB gene_id:6257|Hs108|chr6 ( 533) 724 122.9 7.9e-28
CCDS55828.1 NR4A1 gene_id:3164|Hs108|chr12 ( 611) 725 123.1 7.9e-28
CCDS73471.1 NR4A1 gene_id:3164|Hs108|chr12 ( 652) 725 123.1 8.4e-28
CCDS1517.1 ESRRG gene_id:2104|Hs108|chr1 ( 435) 712 121.0 2.4e-27
CCDS41468.1 ESRRG gene_id:2104|Hs108|chr1 ( 458) 712 121.0 2.5e-27
CCDS59007.1 RXRB gene_id:6257|Hs108|chr6 ( 537) 712 121.0 2.9e-27
CCDS2201.1 NR4A2 gene_id:4929|Hs108|chr2 ( 598) 709 120.6 4.3e-27
CCDS58061.1 ESRRG gene_id:2104|Hs108|chr1 ( 470) 701 119.3 8.4e-27
CCDS9850.2 ESRRB gene_id:2103|Hs108|chr14 ( 508) 669 114.4 2.8e-25
CCDS6743.1 NR4A3 gene_id:8013|Hs108|chr9 ( 626) 657 112.6 1.2e-24
CCDS6742.1 NR4A3 gene_id:8013|Hs108|chr9 ( 637) 657 112.6 1.2e-24
CCDS12352.1 NR2F6 gene_id:2063|Hs108|chr19 ( 404) 615 106.0 7.5e-23
CCDS10375.1 NR2F2 gene_id:7026|Hs108|chr15 ( 414) 608 104.9 1.6e-22
CCDS4068.1 NR2F1 gene_id:7025|Hs108|chr5 ( 423) 599 103.5 4.3e-22
CCDS60830.1 ESRRA gene_id:2101|Hs108|chr11 ( 422) 545 95.2 1.4e-19
CCDS42316.1 THRA gene_id:7067|Hs108|chr17 ( 410) 530 92.8 6.8e-19
CCDS2641.1 THRB gene_id:7068|Hs108|chr3 ( 461) 497 87.8 2.6e-17
CCDS58546.1 THRA gene_id:7067|Hs108|chr17 ( 451) 448 80.2 4.8e-15
CCDS11360.1 THRA gene_id:7067|Hs108|chr17 ( 490) 446 79.9 6.4e-15
CCDS58673.1 NR1H2 gene_id:7376|Hs108|chr19 ( 363) 443 79.4 6.9e-15
CCDS42593.1 NR1H2 gene_id:7376|Hs108|chr19 ( 460) 443 79.4 8.3e-15
CCDS1248.1 RXRG gene_id:6258|Hs108|chr1 ( 463) 430 77.4 3.4e-14
CCDS72970.1 RXRG gene_id:6258|Hs108|chr1 ( 340) 422 76.1 6.2e-14
CCDS10177.1 RORA gene_id:6095|Hs108|chr15 ( 523) 419 75.8 1.2e-13
CCDS45271.1 RORA gene_id:6095|Hs108|chr15 ( 468) 415 75.1 1.7e-13
CCDS10178.1 RORA gene_id:6095|Hs108|chr15 ( 548) 415 75.2 1.9e-13
CCDS10179.1 RORA gene_id:6095|Hs108|chr15 ( 556) 415 75.2 1.9e-13
CCDS33718.1 NR1D2 gene_id:9975|Hs108|chr3 ( 579) 412 74.7 2.8e-13
CCDS41821.1 NR2C1 gene_id:7181|Hs108|chr12 ( 467) 410 74.3 2.9e-13
CCDS44953.1 NR2C1 gene_id:7181|Hs108|chr12 ( 483) 410 74.3 3e-13
CCDS1004.1 RORC gene_id:6097|Hs108|chr1 ( 518) 410 74.4 3.1e-13
CCDS9051.1 NR2C1 gene_id:7181|Hs108|chr12 ( 603) 410 74.4 3.5e-13
CCDS74905.1 NR2C2 gene_id:7182|Hs108|chr3 ( 596) 406 73.8 5.4e-13
CCDS6646.1 RORB gene_id:6096|Hs108|chr9 ( 459) 404 73.4 5.4e-13
CCDS2621.1 NR2C2 gene_id:7182|Hs108|chr3 ( 615) 406 73.8 5.5e-13
CCDS30856.1 RORC gene_id:6097|Hs108|chr1 ( 497) 403 73.3 6.4e-13
CCDS6744.1 NR4A3 gene_id:8013|Hs108|chr9 ( 443) 402 73.1 6.5e-13
CCDS58060.1 ESRRG gene_id:2104|Hs108|chr1 ( 396) 396 72.1 1.1e-12
CCDS47298.1 NR3C1 gene_id:2908|Hs108|chr5 ( 742) 399 72.8 1.4e-12
>>CCDS8850.1 RARG gene_id:5916|Hs108|chr12 (454 aa)
initn: 3103 init1: 3103 opt: 3103 Z-score: 2601.0 bits: 490.5 E(32554): 1.5e-138
Smith-Waterman score: 3103; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KB5 MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
370 380 390 400 410 420
430 440 450
pF1KB5 MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
::::::::::::::::::::::::::::::::::
CCDS88 MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
430 440 450
>>CCDS41790.1 RARG gene_id:5916|Hs108|chr12 (443 aa)
initn: 2724 init1: 2692 opt: 2700 Z-score: 2264.6 bits: 428.2 E(32554): 8.1e-120
Smith-Waterman score: 2700; 92.3% identity (93.7% similar) in 442 aa overlap (13-454:9-443)
10 20 30 40 50 60
pF1KB5 MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
: :: : .:: : : : :: . . : :: . :. .
CCDS41 MYDCMETFAPGPRRLYGAAG-PGA--GLLRRATG----GSCFAGLESFAWPQPASL
10 20 30 40
70 80 90 100 110 120
pF1KB5 LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 QSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
350 360 370 380 390 400
430 440 450
pF1KB5 MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
::::::::::::::::::::::::::::::::::
CCDS41 MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
410 420 430 440
>>CCDS58236.1 RARG gene_id:5916|Hs108|chr12 (382 aa)
initn: 2618 init1: 2618 opt: 2618 Z-score: 2197.0 bits: 415.5 E(32554): 4.7e-116
Smith-Waterman score: 2618; 100.0% identity (100.0% similar) in 382 aa overlap (73-454:1-382)
50 60 70 80 90 100
pF1KB5 SPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHY
::::::::::::::::::::::::::::::
CCDS58 MVPSSPSPPPPPRVYKPCFVCNDKSSGYHY
10 20 30
110 120 130 140 150 160
pF1KB5 GVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRN
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB5 DRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB5 DLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB5 QDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 QDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRM
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB5 DLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKM
280 290 300 310 320 330
410 420 430 440 450
pF1KB5 EIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
340 350 360 370 380
>>CCDS58237.1 RARG gene_id:5916|Hs108|chr12 (432 aa)
initn: 2325 init1: 2325 opt: 2325 Z-score: 1951.5 bits: 370.3 E(32554): 2.2e-102
Smith-Waterman score: 2325; 99.7% identity (100.0% similar) in 345 aa overlap (110-454:88-432)
80 90 100 110 120 130
pF1KB5 PPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTR
:.::::::::::::::::::::::::::::
CCDS58 PGPGPACCAEPPAAPVSPDLNLLPGRNPPACNGFFRRSIQKNMVYTCHRDKNCIINKVTR
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB5 NRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 NRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQE
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB5 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB5 ITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLL
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB5 PLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 PLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRM
300 310 320 330 340 350
380 390 400 410 420 430
pF1KB5 LMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSED
360 370 380 390 400 410
440 450
pF1KB5 EVPGGQGKGGLKSPA
:::::::::::::::
CCDS58 EVPGGQGKGGLKSPA
420 430
>>CCDS2642.1 RARB gene_id:5915|Hs108|chr3 (448 aa)
initn: 2230 init1: 2193 opt: 2199 Z-score: 1846.1 bits: 350.8 E(32554): 1.7e-96
Smith-Waterman score: 2199; 78.0% identity (90.6% similar) in 413 aa overlap (42-453:33-445)
20 30 40 50 60 70
pF1KB5 GALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSE
:. : :: : . .. .. :.::::::::
CCDS26 DCMDVLSVSPGQILDFYTASPSSCMLQEKALKACFSGLTQTEWQHRHTAQSIETQSTSSE
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 EMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKN
:.::: ::: ::::::::::::.:::::::::::.::::::::::::::::.::::::::
CCDS26 ELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKN
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 CIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELIT
:.:::::::::::::::::::::::::.:::::::::::.... .:::.. .:..:
CCDS26 CVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 KVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGF
:. ::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
CCDS26 KIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGF
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB5 TGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLV
:::.::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
CCDS26 TGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLV
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB5 FAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPS
:.::.:::::::::::::::::::::::::.::::: :::::::::::::..: :.::::
CCDS26 FTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPS
310 320 330 340 350 360
380 390 400 410 420 430
pF1KB5 QPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGP
.:.:::..::::::::.::.:::::.::::::::: :::::.::::: : : . . .
CCDS26 KPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSG
370 380 390 400 410 420
440 450
pF1KB5 HPNASSEDEVPGGQGKGGL-KSPA
. : . :.. ..:. .::
CCDS26 NTAEHSPSISPSSVENSGVSQSPLVQ
430 440
>>CCDS11366.1 RARA gene_id:5914|Hs108|chr17 (462 aa)
initn: 2195 init1: 2121 opt: 2167 Z-score: 1819.2 bits: 345.9 E(32554): 5.2e-95
Smith-Waterman score: 2176; 72.1% identity (84.5% similar) in 458 aa overlap (1-453:1-440)
10 20 30 40 50
pF1KB5 MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRG-SPPFEMLSPSFR----GLGQPDLP
::.:. . :. : .::: . : :: : : ::: . . . . : . :. :
CCDS11 MASNSSSCPTPGG-GHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPS-P
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 KEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFR
..::::.::::.::: ::::: ::.:::::::.:::::::::::.:::::::::
CCDS11 A-----TIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 RSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEG
:::::::::::::::::::::::::::::::::::::::::::.:::::::::::: .
CCDS11 RSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 SPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELAT
.:: :.:.. ::: :: ::::::::.::::::::::.:...::.::. ::::::::.:
CCDS11 CSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELST
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 KCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLN
::::: :::::.::::: :.::::::::::::::::.:::::::::::::::::::::::
CCDS11 KCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 RTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQE
::::::::::::::::::::.:::::::::.:::::::::::::::.:::.:..:: :::
CCDS11 RTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQE
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 PLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREM
::::::..:.:.::::.:.:::.:::::::::.::.:::::.::::::::: :::::.::
CCDS11 PLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEM
360 370 380 390 400 410
420 430 440 450
pF1KB5 LENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
::: : .. :.::: ::. ::: :
CCDS11 LENSEGLDTLSGQPGG-----------GGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
420 430 440 450 460
>>CCDS42317.1 RARA gene_id:5914|Hs108|chr17 (457 aa)
initn: 2153 init1: 2124 opt: 2124 Z-score: 1783.3 bits: 339.2 E(32554): 5.2e-93
Smith-Waterman score: 2134; 73.4% identity (85.2% similar) in 440 aa overlap (14-453:28-435)
10 20 30 40
pF1KB5 MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSF
: : .: :. : :.. : :: .: .
CCDS42 MYESVEVGGPTPNPFLVVDFYNQNRACLLPEKGLPAPG-PYSTP--LR--------TPLW
10 20 30 40
50 60 70 80 90 100
pF1KB5 RGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSS
: .. :.::::.::::.::: ::::: ::.:::::::.:::::::::::.
CCDS42 NG----------SNHSIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSA
50 60 70 80 90
110 120 130 140 150 160
pF1KB5 CEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
CCDS42 CEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNK
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB5 KKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGL
::::: . .:: :.:.. ::: :: ::::::::.::::::::::.:...::.::. :
CCDS42 KKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDL
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB5 WDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTM
:::::::.:::::: :::::.::::: :.::::::::::::::::.::::::::::::::
CCDS42 WDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTM
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB5 TFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEE
:::::::::::::::::::::::::::::.:::::::::.:::::::::::::::.:::.
CCDS42 TFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQ
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB5 PEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPG
:..:: :::::::::..:.:.::::.:.:::.:::::::::.::.:::::.:::::::::
CCDS42 PDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG
340 350 360 370 380 390
410 420 430 440 450
pF1KB5 PMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
:::::.::::: : .. :.::: ::. ::: :
CCDS42 SMPPLIQEMLENSEGLDTLSGQPGG-----------GGRDGGGLAPPPGSCSPSLSPSSN
400 410 420 430 440
CCDS42 RSSPATHSP
450
>>CCDS46775.1 RARB gene_id:5915|Hs108|chr3 (336 aa)
initn: 1784 init1: 1760 opt: 1777 Z-score: 1495.4 bits: 285.5 E(32554): 5.7e-77
Smith-Waterman score: 1777; 79.0% identity (91.6% similar) in 333 aa overlap (122-453:1-333)
100 110 120 130 140 150
pF1KB5 VCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCF
:.:::::::::.::::::::::::::::::
CCDS46 MIYTCHRDKNCVINKVTRNRCQYCRLQKCF
10 20 30
160 170 180 190 200 210
pF1KB5 EVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYT
:::::::.:::::::::::.... .:::.. .:..: :. :::::::::::::::::
CCDS46 EVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYT
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB5 TNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDIL
:::::::::.:::::::::::::::::::::::::::::::::.::::::::::::::::
CCDS46 TNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDIL
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB5 MLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLL
.::::::::::::::::::::::::::::::::::::::::.::.:::::::::::::::
CCDS46 ILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLL
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 SAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGIST
::::::::::.::::: :::::::::::::..: :.::::.:.:::..::::::::.::.
CCDS46 SAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISA
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 KGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGL-
:::::.::::::::: :::::.::::: : : . . . . : . :.. ..:.
CCDS46 KGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNTAEHSPSISPSSVENSGVS
280 290 300 310 320 330
pF1KB5 KSPA
.::
CCDS46 QSPLVQ
>>CCDS45671.1 RARA gene_id:5914|Hs108|chr17 (365 aa)
initn: 1533 init1: 1460 opt: 1460 Z-score: 1230.1 bits: 236.5 E(32554): 3.4e-62
Smith-Waterman score: 1469; 75.2% identity (87.9% similar) in 298 aa overlap (156-453:57-343)
130 140 150 160 170 180
pF1KB5 CHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQ
: .:::::::::::: . .:: :.:.
CCDS45 FFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPATVRNDRNKKKKEVPKPECSESYTLTPE
30 40 50 60 70 80
190 200 210 220 230 240
pF1KB5 LEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFA
. ::: :: ::::::::.::::::::::.:...::.::. ::::::::.:::::: ::::
CCDS45 VGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFA
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB5 KRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG
:.::::: :.::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS45 KQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB5 PLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYA
::::::::::.:::::::::.:::::::::::::::.:::.:..:: :::::::::..:.
CCDS45 PLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYV
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB5 RRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDD
:.::::.:.:::.:::::::::.::.:::::.::::::::: :::::.::::: : ..
CCDS45 RKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTL
270 280 290 300 310 320
430 440 450
pF1KB5 SSQPGPHPNASSEDEVPGGQGKGGLKSPA
:.::: ::. ::: :
CCDS45 SGQPGG-----------GGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
330 340 350 360
>>CCDS35172.1 RXRA gene_id:6256|Hs108|chr9 (462 aa)
initn: 770 init1: 406 opt: 739 Z-score: 626.5 bits: 125.2 E(32554): 1.4e-28
Smith-Waterman score: 756; 32.6% identity (60.4% similar) in 432 aa overlap (13-419:36-458)
10 20 30
pF1KB5 MATNKERLFAAGALGPGSGYPGAGF-PFA-FPGALRG-SPPF
.:::: : :: :.. . . . : .:::
CCDS35 FLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPF
10 20 30 40 50 60
40 50 60 70 80
pF1KB5 EMLSPSF--RGLGQPDLPKEMASLSVETQST------SSEEM-----------VPSSPSP
..: . .... : : : . :. :::.. ::. ::
CCDS35 SVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSG
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB5 PPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRN
. . : .:.:.::: :::: :::::::::.:...:...:::. .:.:.:.: ::
CCDS35 NMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRN
130 140 150 160 170 180
150 160 170 180 190
pF1KB5 RCQYCRLQKCFEVGMSKEAVRNDRN--KKKKEVKEEGSPDSYELSPQLEELITKVSKAHQ
:::::: :::. .::..:::...:. : ..: . :.. .. : : : : .. : .
CCDS35 RCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPV--ERILEAELAVE
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB5 ETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIAD
. . . . :: . : .. . : : .. .::.:::.: :. : . :
CCDS35 PKTETYVEANMGLNPSSPNDPV-------TNICQAADKQLFTLVEWAKRIPHFSELPLDD
250 260 270 280 290
260 270 280 290 300 310
pF1KB5 QITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFA-FAGQ
:. ::.:. ..:. . : .: . .. :: ..:.. :.:: : . : :.. ....
CCDS35 QVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSK
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB5 LLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFP
. ..:: :: : : :: :. : : .: .:. :.: . .:. : ... : :: :
CCDS35 MRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFA
360 370 380 390 400 410
380 390 400 410 420 430
pF1KB5 RMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASS
..:... ::.:. : :. . .:. :. .. :::: :
CCDS35 KLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
420 430 440 450 460
440 450
pF1KB5 EDEVPGGQGKGGLKSPA
454 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:23:39 2016 done: Sat Nov 5 10:23:39 2016
Total Scan time: 3.290 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]