Result of FASTA (omim) for
pF1KB5798
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5798, 781 aa
1>>>pF1KB5798 781 - 781 aa - 781 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7166+/-0.000437; mu= 7.0769+/- 0.027
mean_var=265.5383+/-53.106, 0's: 0 Z-trim(119.2): 206 B-trim: 0 in 0/58
Lambda= 0.078707
statistics sampled from 32787 (33014) to 32787 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.387), width: 16
Scan time: 14.060
The best scores are: opt bits E(85289)
NP_000234 (OMIM: 134610,249100,608107) pyrin isofo ( 781) 5267 612.1 2.9e-174
XP_016878725 (OMIM: 134610,249100,608107) PREDICTE ( 780) 5249 610.0 1.2e-173
NP_001185465 (OMIM: 134610,249100,608107) pyrin is ( 445) 1937 233.7 1.3e-60
NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 1187 148.6 6.2e-35
NP_001017922 (OMIM: 111620,111750,609017) erythroi ( 475) 720 95.6 5.4e-19
XP_006710376 (OMIM: 111620,111750,609017) PREDICTE ( 475) 720 95.6 5.4e-19
XP_011538872 (OMIM: 111620,111750,609017) PREDICTE ( 475) 720 95.6 5.4e-19
NP_061008 (OMIM: 111620,111750,609017) erythroid m ( 475) 720 95.6 5.4e-19
XP_011538873 (OMIM: 111620,111750,609017) PREDICTE ( 468) 712 94.6 1e-18
NP_003132 (OMIM: 109092) E3 ubiquitin-protein liga ( 475) 684 91.5 9.2e-18
NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 680 91.1 1.3e-17
NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 666 89.4 3.9e-17
NP_060543 (OMIM: 613184) E3 ubiquitin-protein liga ( 485) 640 86.5 3e-16
NP_001291425 (OMIM: 613184) E3 ubiquitin-protein l ( 262) 610 82.8 2.1e-15
NP_001723 (OMIM: 601610) butyrophilin subfamily 1 ( 526) 589 80.7 1.8e-14
XP_005249397 (OMIM: 601610) PREDICTED: butyrophili ( 626) 589 80.8 2e-14
XP_011512533 (OMIM: 613591) PREDICTED: butyrophili ( 313) 567 78.0 6.9e-14
NP_001184168 (OMIM: 613591) butyrophilin subfamily ( 313) 567 78.0 6.9e-14
XP_006715046 (OMIM: 613593) PREDICTED: butyrophili ( 419) 569 78.4 7.2e-14
NP_001138480 (OMIM: 613593) butyrophilin subfamily ( 461) 569 78.4 7.7e-14
NP_853509 (OMIM: 613591) butyrophilin subfamily 2 ( 407) 567 78.1 8.3e-14
XP_005248855 (OMIM: 613591) PREDICTED: butyrophili ( 407) 567 78.1 8.3e-14
XP_016865656 (OMIM: 613591) PREDICTED: butyrophili ( 407) 567 78.1 8.3e-14
NP_008979 (OMIM: 613593) butyrophilin subfamily 3 ( 513) 569 78.4 8.3e-14
XP_016865655 (OMIM: 613591) PREDICTED: butyrophili ( 461) 567 78.2 9e-14
XP_011512531 (OMIM: 613591) PREDICTED: butyrophili ( 461) 567 78.2 9e-14
NP_008926 (OMIM: 613591) butyrophilin subfamily 2 ( 523) 567 78.2 9.9e-14
NP_001184166 (OMIM: 613591) butyrophilin subfamily ( 523) 567 78.2 9.9e-14
XP_006715016 (OMIM: 613591) PREDICTED: butyrophili ( 523) 567 78.2 9.9e-14
XP_011512530 (OMIM: 613591) PREDICTED: butyrophili ( 523) 567 78.2 9.9e-14
XP_005248854 (OMIM: 613591) PREDICTED: butyrophili ( 523) 567 78.2 9.9e-14
NP_001184162 (OMIM: 613590) butyrophilin subfamily ( 466) 555 76.8 2.3e-13
NP_008925 (OMIM: 613595) butyrophilin subfamily 3 ( 584) 556 77.0 2.5e-13
NP_008980 (OMIM: 613590) butyrophilin subfamily 2 ( 527) 555 76.9 2.5e-13
NP_001229732 (OMIM: 613595) butyrophilin subfamily ( 374) 552 76.4 2.6e-13
NP_932078 (OMIM: 613595) butyrophilin subfamily 3 ( 535) 552 76.5 3.3e-13
XP_005248890 (OMIM: 613593) PREDICTED: butyrophili ( 506) 548 76.1 4.3e-13
XP_011542587 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 391) 543 75.4 5.3e-13
XP_016857901 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 467) 541 75.2 7.1e-13
NP_660215 (OMIM: 607868) E3 ubiquitin-protein liga ( 468) 541 75.2 7.1e-13
NP_892030 (OMIM: 616017) E3 ubiquitin-protein liga ( 500) 526 73.5 2.4e-12
XP_016884390 (OMIM: 605968) PREDICTED: ret finger ( 288) 508 71.3 6.8e-12
XP_016884391 (OMIM: 605968) PREDICTED: ret finger ( 288) 508 71.3 6.8e-12
XP_016884389 (OMIM: 605968) PREDICTED: ret finger ( 288) 508 71.3 6.8e-12
XP_011528601 (OMIM: 605968) PREDICTED: ret finger ( 288) 508 71.3 6.8e-12
XP_011528600 (OMIM: 605968) PREDICTED: ret finger ( 288) 508 71.3 6.8e-12
NP_066306 (OMIM: 605968) ret finger protein-like 1 ( 317) 508 71.3 7.3e-12
NP_001288075 (OMIM: 616017) E3 ubiquitin-protein l ( 263) 504 70.8 8.8e-12
NP_001288074 (OMIM: 616017) E3 ubiquitin-protein l ( 279) 504 70.8 9.1e-12
NP_001288073 (OMIM: 616017) E3 ubiquitin-protein l ( 296) 504 70.8 9.5e-12
>>NP_000234 (OMIM: 134610,249100,608107) pyrin isoform 1 (781 aa)
initn: 5267 init1: 5267 opt: 5267 Z-score: 3249.6 bits: 612.1 E(85289): 2.9e-174
Smith-Waterman score: 5267; 100.0% identity (100.0% similar) in 781 aa overlap (1-781:1-781)
10 20 30 40 50 60
pF1KB5 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRREKASEGLDAQGKPRTRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRREKASEGLDAQGKPRTRSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ALPGGRSPGPCRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLPSGKMRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ALPGGRSPGPCRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLPSGKMRP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 RSLEVTISTGEKAPANPEILLTLEEKTAANLDSATEPRARPTPDGGASADLKEGPGNPEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RSLEVTISTGEKAPANPEILLTLEEKTAANLDSATEPRARPTPDGGASADLKEGPGNPEH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 RKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 VPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 ILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 DKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 FVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGP
730 740 750 760 770 780
pF1KB5 D
:
NP_000 D
>>XP_016878725 (OMIM: 134610,249100,608107) PREDICTED: p (780 aa)
initn: 2872 init1: 2872 opt: 5249 Z-score: 3238.6 bits: 610.0 E(85289): 1.2e-173
Smith-Waterman score: 5249; 99.9% identity (99.9% similar) in 781 aa overlap (1-781:1-780)
10 20 30 40 50 60
pF1KB5 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRREKASEGLDAQGKPRTRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRREKASEGLDAQGKPRTRSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ALPGGRSPGPCRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLPSGKMRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALPGGRSPGPCRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLPSGKMRP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 RSLEVTISTGEKAPANPEILLTLEEKTAANLDSATEPRARPTPDGGASADLKEGPGNPEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLEVTISTGEKAPANPEILLTLEEKTAANLDSATEPRARPTPDGGASADLKEGPGNPEH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 RKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 K-IQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF
430 440 450 460 470
490 500 510 520 530 540
pF1KB5 VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB5 VPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNV
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB5 ILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVG
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB5 DKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGI
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB5 FVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGP
720 730 740 750 760 770
pF1KB5 D
:
XP_016 D
780
>>NP_001185465 (OMIM: 134610,249100,608107) pyrin isofor (445 aa)
initn: 1937 init1: 1937 opt: 1937 Z-score: 1209.1 bits: 233.7 E(85289): 1.3e-60
Smith-Waterman score: 2078; 64.0% identity (64.0% similar) in 586 aa overlap (1-586:1-375)
10 20 30 40 50 60
pF1KB5 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT
::::::::::::::::::::::::::::::::
NP_001 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQ----------------------------
70 80 90
130 140 150 160 170 180
pF1KB5 PDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRREKASEGLDAQGKPRTRSP
NP_001 ------------------------------------------------------------
190 200 210 220 230 240
pF1KB5 ALPGGRSPGPCRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLPSGKMRP
NP_001 ------------------------------------------------------------
250 260 270 280 290 300
pF1KB5 RSLEVTISTGEKAPANPEILLTLEEKTAANLDSATEPRARPTPDGGASADLKEGPGNPEH
NP_001 ------------------------------------------------------------
310 320 330 340 350 360
pF1KB5 SVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---GRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHE
100 110 120 130 140
370 380 390 400 410 420
pF1KB5 RKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHK
150 160 170 180 190 200
430 440 450 460 470 480
pF1KB5 KKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF
210 220 230 240 250 260
490 500 510 520 530 540
pF1KB5 VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT
270 280 290 300 310 320
550 560 570 580 590 600
pF1KB5 VPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNV
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNDHSPQHGLGSWEER
330 340 350 360 370 380
610 620 630 640 650 660
pF1KB5 ILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVG
NP_001 DYTQHSMQGPKQGVPCLSLLSGQCNLAPLNANAQDFFPYLIFLRSSRADWRSGTCC
390 400 410 420 430 440
>>NP_006501 (OMIM: 602165) zinc finger protein RFP [Homo (513 aa)
initn: 761 init1: 619 opt: 1187 Z-score: 748.1 bits: 148.6 E(85289): 6.2e-35
Smith-Waterman score: 1191; 38.6% identity (68.7% similar) in 485 aa overlap (313-777:17-494)
290 300 310 320 330 340
pF1KB5 PDGGASADLKEGPGNPEHSVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHP
: : ..:. : .. : : ..
NP_006 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICC---ACLARC
10 20 30 40
350 360 370 380
pF1KB5 QASGSRSPGCPRCQDS----HER------------KSPGSLSPQ-P---LPQCKRHLKQV
... . .::.:... : : :. . :. : . :..: . .
NP_006 WGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPL
50 60 70 80 90 100
390 400 410 420 430 440
pF1KB5 QLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRS
.: .::. . :::..:. :.::.:: : :.::.. :..::.::.:::... ...:.
NP_006 KL-YCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRA
110 120 130 140 150 160
450 460 470 480 490 500
pF1KB5 YGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRV
::. . .:. :. .... ..::.:. :...:. ..: ::.. . . .. :.
NP_006 QGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQF
170 180 190 200 210 220
510 520 530 540 550 560
pF1KB5 SQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQ
: .:. :..::..:: :. : :::::::: : ::. . .:: : :: ....::... :
NP_006 SCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQ
230 240 250 260 270 280
570 580 590 600 610 620
pF1KB5 KSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRL
: :. .: : :.: ..:.:: .. :: :: ..:.: :: .::::.::.::.:..::
NP_006 KCLFLTESLKQFTEKMQSDME--KIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRY
290 300 310 320 330 340
630 640 650 660 670 680
pF1KB5 GNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTL
. . :::.:.::. ::::: :..::.:::::::::. : .:.:. :. :::..:
NP_006 SYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTS
350 360 370 380 390 400
690 700 710 720 730 740
pF1KB5 SPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYT
.:.::.:.: . .:: : . : : : .. : .:::::.:: .: .:::::: : : .:
NP_006 APQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFT
410 420 430 440 450 460
750 760 770 780
pF1KB5 FASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
:. .: ::..: :: . .:::..::: :::..:
NP_006 FSHATFCGPVRPYFSL-SYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
470 480 490 500 510
>>NP_001017922 (OMIM: 111620,111750,609017) erythroid me (475 aa)
initn: 711 init1: 584 opt: 720 Z-score: 461.9 bits: 95.6 E(85289): 5.4e-19
Smith-Waterman score: 720; 53.8% identity (76.9% similar) in 199 aa overlap (578-773:215-412)
550 560 570 580 590 600
pF1KB5 TTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIG---AQAHAVNVILDA
::::... . : :. : : : ::
NP_001 KLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAVTLDP
190 200 210 220 230 240
610 620 630 640 650 660
pF1KB5 ETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTA
.::.:.::.:.: . ::::.. . .::.::::: . .::: : .: .:::: :::::
NP_001 DTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTK
250 260 270 280 290 300
670 680 690 700 710 720
pF1KB5 WILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDY
::::.:. :.::::..: :: ::.:.. . . :::.: . : : . .::::. ::::.::
NP_001 WILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDY
310 320 330 340 350 360
730 740 750 760 770 780
pF1KB5 RVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
..: ::::::: .:::.::. .:::::.:.: : .:::::::::.::
NP_001 EAGVISFYNVTNKSHIFTFTH-NFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEESIV
370 380 390 400 410 420
NP_001 PRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
430 440 450 460 470
>>XP_006710376 (OMIM: 111620,111750,609017) PREDICTED: e (475 aa)
initn: 711 init1: 584 opt: 720 Z-score: 461.9 bits: 95.6 E(85289): 5.4e-19
Smith-Waterman score: 720; 53.8% identity (76.9% similar) in 199 aa overlap (578-773:215-412)
550 560 570 580 590 600
pF1KB5 TTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIG---AQAHAVNVILDA
::::... . : :. : : : ::
XP_006 KLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAVTLDP
190 200 210 220 230 240
610 620 630 640 650 660
pF1KB5 ETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTA
.::.:.::.:.: . ::::.. . .::.::::: . .::: : .: .:::: :::::
XP_006 DTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTK
250 260 270 280 290 300
670 680 690 700 710 720
pF1KB5 WILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDY
::::.:. :.::::..: :: ::.:.. . . :::.: . : : . .::::. ::::.::
XP_006 WILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDY
310 320 330 340 350 360
730 740 750 760 770 780
pF1KB5 RVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
..: ::::::: .:::.::. .:::::.:.: : .:::::::::.::
XP_006 EAGVISFYNVTNKSHIFTFTH-NFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEESIV
370 380 390 400 410 420
XP_006 PRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
430 440 450 460 470
>>XP_011538872 (OMIM: 111620,111750,609017) PREDICTED: e (475 aa)
initn: 711 init1: 584 opt: 720 Z-score: 461.9 bits: 95.6 E(85289): 5.4e-19
Smith-Waterman score: 720; 53.8% identity (76.9% similar) in 199 aa overlap (578-773:215-412)
550 560 570 580 590 600
pF1KB5 TTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIG---AQAHAVNVILDA
::::... . : :. : : : ::
XP_011 KLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAVTLDP
190 200 210 220 230 240
610 620 630 640 650 660
pF1KB5 ETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTA
.::.:.::.:.: . ::::.. . .::.::::: . .::: : .: .:::: :::::
XP_011 DTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTK
250 260 270 280 290 300
670 680 690 700 710 720
pF1KB5 WILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDY
::::.:. :.::::..: :: ::.:.. . . :::.: . : : . .::::. ::::.::
XP_011 WILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDY
310 320 330 340 350 360
730 740 750 760 770 780
pF1KB5 RVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
..: ::::::: .:::.::. .:::::.:.: : .:::::::::.::
XP_011 EAGVISFYNVTNKSHIFTFTH-NFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEESIV
370 380 390 400 410 420
XP_011 PRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
430 440 450 460 470
>>NP_061008 (OMIM: 111620,111750,609017) erythroid membr (475 aa)
initn: 711 init1: 584 opt: 720 Z-score: 461.9 bits: 95.6 E(85289): 5.4e-19
Smith-Waterman score: 720; 53.8% identity (76.9% similar) in 199 aa overlap (578-773:215-412)
550 560 570 580 590 600
pF1KB5 TTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIG---AQAHAVNVILDA
::::... . : :. : : : ::
NP_061 KLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAVTLDP
190 200 210 220 230 240
610 620 630 640 650 660
pF1KB5 ETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTA
.::.:.::.:.: . ::::.. . .::.::::: . .::: : .: .:::: :::::
NP_061 DTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTK
250 260 270 280 290 300
670 680 690 700 710 720
pF1KB5 WILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDY
::::.:. :.::::..: :: ::.:.. . . :::.: . : : . .::::. ::::.::
NP_061 WILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDY
310 320 330 340 350 360
730 740 750 760 770 780
pF1KB5 RVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
..: ::::::: .:::.::. .:::::.:.: : .:::::::::.::
NP_061 EAGVISFYNVTNKSHIFTFTH-NFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEESIV
370 380 390 400 410 420
NP_061 PRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
430 440 450 460 470
>>XP_011538873 (OMIM: 111620,111750,609017) PREDICTED: e (468 aa)
initn: 711 init1: 584 opt: 712 Z-score: 457.1 bits: 94.6 E(85289): 1e-18
Smith-Waterman score: 712; 56.4% identity (79.6% similar) in 181 aa overlap (593-773:226-405)
570 580 590 600 610 620
pF1KB5 KSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRL
:. : : : :: .::.:.::.:.: . :::
XP_011 NLLSDHAKEKGKLHKAVKLKRAAANSGWRRARLHFVAVTLDPDTAHPKLILSEDQRCVRL
200 210 220 230 240 250
630 640 650 660 670 680
pF1KB5 GNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTL
:.. . .::.::::: . .::: : .: .:::: ::::: ::::.:. :.::::..:
XP_011 GDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTA
260 270 280 290 300 310
690 700 710 720 730 740
pF1KB5 SPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYT
:: ::.:.. . . :::.: . : : . .::::. ::::.::..: ::::::: .:::.:
XP_011 SPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFT
320 330 340 350 360 370
750 760 770 780
pF1KB5 FASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
: . .:::::.:.: : .:::::::::.::
XP_011 F-THNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEESIVPRPEGKGHANGDVSLKVN
380 390 400 410 420 430
XP_011 SSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
440 450 460
>>NP_003132 (OMIM: 109092) E3 ubiquitin-protein ligase T (475 aa)
initn: 891 init1: 465 opt: 684 Z-score: 439.8 bits: 91.5 E(85289): 9.2e-18
Smith-Waterman score: 872; 33.2% identity (61.9% similar) in 485 aa overlap (313-779:17-471)
290 300 310 320 330 340
pF1KB5 PDGGASADLKEGPGNPEHSVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHP
: : .::. : .. :. : .:
NP_003 MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQ--ECISQVG
10 20 30 40
350 360 370 380
pF1KB5 QASGSRSPGC----------PRCQDSHERKSPGSLSPQPLP-----QCKRHLKQVQLLFC
...:: : : : : .. .. .: . .: : ....: ::
NP_003 KGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHL-FC
50 60 70 80 90 100
390 400 410 420 430 440
pF1KB5 EDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEK
: . .: .:. :..:. : . :.::.: :...:.: : .:.. .. .:. . :
NP_003 EKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIK
110 120 130 140 150 160
450 460 470 480 490 500
pF1KB5 AVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIA
... : .:. :.:.. .. : :: ..:. . :: . .: .....:.
NP_003 RADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQ
170 180 190 200 210 220
510 520 530 540 550 560
pF1KB5 LLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFV
:. ::.::. . .: ::::.. .:.:. :.:.
NP_003 ALQELISELDRRCHSSALELLQEVIIVLERS------ESWNL------------------
230 240 250
570 580 590 600 610 620
pF1KB5 EKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWE
:. : ::: .. .. ... .. ::.. :: .:: : ::.:.: ..::::. .
NP_003 -KDLDITSPELRSVCHVPGLKKML--RTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQ
260 270 280 290 300 310
630 640 650 660 670 680
pF1KB5 RLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENG
.: . .:::: .:::. : ::..::::.: : :: ::.:. :. :::.. :: ..:
NP_003 SIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSG
320 330 340 350 360 370
690 700 710 720 730 740
pF1KB5 YWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTAR-SHIYTFASC
.:.. . ....:.:.. : : : .. :: .::::.::..: .::::.: . : ::.:. :
NP_003 FWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSEC
380 390 400 410 420 430
750 760 770 780
pF1KB5 SFSGPLQPIFSPGTRDGGKNTAPLTICP--VGGQGPD
.:.:::.:.:::: ::::::::::.:: .:.::
NP_003 AFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
440 450 460 470
781 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:23:16 2016 done: Sat Nov 5 16:23:18 2016
Total Scan time: 14.060 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]