Result of FASTA (omim) for
pF1KB5749
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5749, 808 aa
1>>>pF1KB5749 808 - 808 aa - 808 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.1419+/-0.000524; mu= 2.8463+/- 0.033
mean_var=215.2204+/-43.456, 0's: 0 Z-trim(114.2): 41 B-trim: 0 in 0/53
Lambda= 0.087424
statistics sampled from 23916 (23945) to 23916 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.281), width: 16
Scan time: 13.300
The best scores are: opt bits E(85289)
NP_002379 (OMIM: 602693) DNA replication licensing ( 853) 5211 671.2 5.3e-192
NP_001257401 (OMIM: 602693) DNA replication licens ( 818) 4808 620.3 1e-176
NP_004517 (OMIM: 116945,616968) DNA replication li ( 904) 1064 148.1 1.6e-34
NP_005907 (OMIM: 600592) DNA replication licensing ( 719) 1020 142.5 6.2e-33
XP_005250405 (OMIM: 600592) PREDICTED: DNA replica ( 612) 1011 141.3 1.2e-32
XP_016867706 (OMIM: 600592) PREDICTED: DNA replica ( 612) 1011 141.3 1.2e-32
NP_877577 (OMIM: 600592) DNA replication licensing ( 543) 949 133.5 2.5e-30
NP_001265524 (OMIM: 600592) DNA replication licens ( 543) 949 133.5 2.5e-30
XP_006724305 (OMIM: 602696) PREDICTED: DNA replica ( 732) 856 121.8 1.1e-26
NP_006730 (OMIM: 602696) DNA replication licensing ( 734) 856 121.8 1.1e-26
NP_060166 (OMIM: 610098,616185) DNA helicase MCM9 (1143) 768 110.9 3.3e-23
NP_877423 (OMIM: 602638,609981) DNA replication li ( 863) 752 108.8 1.1e-22
NP_005905 (OMIM: 602638,609981) DNA replication li ( 863) 752 108.8 1.1e-22
NP_005906 (OMIM: 223100,601806) DNA replication li ( 821) 750 108.5 1.2e-22
NP_877954 (OMIM: 608187,612885) DNA helicase MCM8 ( 824) 704 102.7 6.9e-21
XP_016883596 (OMIM: 608187,612885) PREDICTED: DNA ( 557) 588 88.0 1.3e-16
XP_016883595 (OMIM: 608187,612885) PREDICTED: DNA ( 776) 588 88.1 1.7e-16
NP_001268449 (OMIM: 608187,612885) DNA helicase MC ( 840) 588 88.1 1.8e-16
NP_115874 (OMIM: 608187,612885) DNA helicase MCM8 ( 840) 588 88.1 1.8e-16
XP_016883594 (OMIM: 608187,612885) PREDICTED: DNA ( 880) 525 80.1 4.5e-14
NP_001268450 (OMIM: 608187,612885) DNA helicase MC ( 880) 525 80.1 4.5e-14
XP_011527689 (OMIM: 608187,612885) PREDICTED: DNA ( 581) 486 75.1 9.8e-13
NP_001268451 (OMIM: 608187,612885) DNA helicase MC ( 793) 420 66.9 4e-10
NP_694987 (OMIM: 610098,616185) DNA helicase MCM9 ( 391) 363 59.5 3.4e-08
>>NP_002379 (OMIM: 602693) DNA replication licensing fac (853 aa)
initn: 5211 init1: 5211 opt: 5211 Z-score: 3568.0 bits: 671.2 E(85289): 5.3e-192
Smith-Waterman score: 5211; 100.0% identity (100.0% similar) in 808 aa overlap (1-808:46-853)
10 20 30
pF1KB5 MAGTVVLDDVELREAQRDYLDFLDDEEDQG
::::::::::::::::::::::::::::::
NP_002 REEFGSFRAGVESSWEPPRDFGGGSSLAAGMAGTVVLDDVELREAQRDYLDFLDDEEDQG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB5 IYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDAT
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB5 YAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPA
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB5 TKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPA
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB5 GQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSK
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB5 DAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLE
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB5 NGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGE
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB5 RRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLA
440 450 460 470 480 490
460 470 480 490 500 510
pF1KB5 AANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAP
500 510 520 530 540 550
520 530 540 550 560 570
pF1KB5 GEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKK
560 570 580 590 600 610
580 590 600 610 620 630
pF1KB5 YIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAK
620 630 640 650 660 670
640 650 660 670 680 690
pF1KB5 ARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRK
680 690 700 710 720 730
700 710 720 730 740 750
pF1KB5 RRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVA
740 750 760 770 780 790
760 770 780 790 800
pF1KB5 LLDVFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQVMVSEGIIFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LLDVFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQVMVSEGIIFLI
800 810 820 830 840 850
>>NP_001257401 (OMIM: 602693) DNA replication licensing (818 aa)
initn: 4808 init1: 4808 opt: 4808 Z-score: 3293.5 bits: 620.3 E(85289): 1e-176
Smith-Waterman score: 4808; 100.0% identity (100.0% similar) in 745 aa overlap (64-808:74-818)
40 50 60 70 80 90
pF1KB5 SKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAK
::::::::::::::::::::::::::::::
NP_001 LWQRAWRVPWCWTMWSCGRLREITWTSWTTRLLNNAFEELVAFQRALKDFVASIDATYAK
50 60 70 80 90 100
100 110 120 130 140 150
pF1KB5 QYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKK
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB5 TIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQL
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB5 PRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQ
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB5 PSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGS
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB5 HIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRL
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB5 EAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAAN
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB5 PVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQ
470 480 490 500 510 520
520 530 540 550 560 570
pF1KB5 DGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIH
530 540 550 560 570 580
580 590 600 610 620 630
pF1KB5 VAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARM
590 600 610 620 630 640
640 650 660 670 680 690
pF1KB5 SKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRK
650 660 670 680 690 700
700 710 720 730 740 750
pF1KB5 TRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVALLD
710 720 730 740 750 760
760 770 780 790 800
pF1KB5 VFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQVMVSEGIIFLI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQVMVSEGIIFLI
770 780 790 800 810
>>NP_004517 (OMIM: 116945,616968) DNA replication licens (904 aa)
initn: 872 init1: 699 opt: 1064 Z-score: 740.8 bits: 148.1 E(85289): 1.6e-34
Smith-Waterman score: 1104; 33.4% identity (64.0% similar) in 677 aa overlap (10-679:193-830)
10 20 30
pF1KB5 MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVREL
.:... ...: : . ..... .. ..
NP_004 EDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDM
170 180 190 200 210 220
40 50 60 70 80 90
pF1KB5 ISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFY
..:. :.:: .:: ... : : . : : :..: . : .. : . ....
NP_004 CKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIH
230 240 250 260 270 280
100 110 120 130 140 150
pF1KB5 VGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRY
: . ... :.: . :. .. . :.::.:. : :.. . : . ..
NP_004 VRISHLPLVEEL--RSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFC
290 300 310 320 330 340
160 170 180 190 200 210
pF1KB5 SDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDV
.. . : :.: : . . .:.:... ..:...: : ::: : :. ::.:::: :.
NP_004 QSQNQEVK-PGSC--P-ECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDA
350 360 370 380 390
220 230 240 250 260 270
pF1KB5 ILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSG--TFRTVLIACNV-KQMSKDAQPSF
:: ::::. ::::.....: :. . . ..: .: ::..: .: :. .: : .
NP_004 ILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAKKDNKVAVGEL
400 410 420 430 440 450
280 290 300 310 320 330
pF1KB5 SAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSH-I
. ::. : ..:: ...: ... :.::::.::. .:... :.:: .. .:.: .
NP_004 TDEDVKMITSLSK--DQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKV
460 470 480 490 500 510
340 350 360 370 380 390
pF1KB5 RGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEA
:::::.:: :::..::::.:.:. .. ::: :::.:.:.::::: : . : :::
NP_004 RGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEA
520 530 540 550 560 570
400 410 420 430 440 450
pF1KB5 GAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPV
::.::::::: :::::::.:.:::.:::.::: ..:.:::: . :.:::.:.:::::.
NP_004 GALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPI
580 590 600 610 620 630
460 470 480 490 500 510
pF1KB5 YGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDG
:::: : ::. : . ..::::.: .. : .:: ::. .. :. : . :....
NP_004 GGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEE
640 650 660 670 680 690
520 530 540 550 560 570
pF1KB5 DAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVA
... :::.. :: .:.. ... .:::: :
NP_004 EGLANGSAAEPAM---PN------------------TYGVEPLPQEV-----LKKYIIYA
700 710 720
580 590 600 610 620 630
pF1KB5 KI-IKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMS
: ..: :.: . .:. :: :: ..::.. . :.:.: .:..::.: :::. ..
NP_004 KERVHPKLNQMDQDKVAKMYSDLR-KESMATGSI---PITVRHIESMIRMAEAHARIHLR
730 740 750 760 770 780
640 650 660 670 680 690
pF1KB5 KTVDLQDAEEAVELVQYAYF--KKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRR
: .:.. :.... ... .: .. :: .. : .:..:
NP_004 DYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLVAEQ
790 800 810 820 830 840
700 710 720 730 740 750
pF1KB5 KTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVALL
NP_004 VTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMILQQ
850 860 870 880 890 900
>>NP_005907 (OMIM: 600592) DNA replication licensing fac (719 aa)
initn: 866 init1: 780 opt: 1020 Z-score: 712.3 bits: 142.5 E(85289): 6.2e-33
Smith-Waterman score: 1093; 35.4% identity (62.1% similar) in 676 aa overlap (5-669:50-655)
10 20 30
pF1KB5 MAGTVVLDDVELREAQRDYLDFLDDEEDQ--GIY
: :::: : . . .: . .. . ..
NP_005 FYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVA--EDDPELVDSICENARRYAKLF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB5 QSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKD--FVASIDAT
. :.::. . . : .:: . : :.: :. ::. .: .: : .
NP_005 ADAVQELLPQYKEREVVNKDVLDVYIEHR-----------LMMEQRS-RDPGMVRSPQNQ
80 90 100 110 120
100 110 120 130 140
pF1KB5 Y-AKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCP
: :. ...: . ..: ..: : . . .. .: :.::::. : :.::.: ... :
NP_005 YPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCD
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB5 AT-KKTIERRYSD-LTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEK
.: . : . :. ::. ... :.:. : : . : . .:: ..
NP_005 QCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTR-G-SRFIKFQEMKMQEHSDQ
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB5 APAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGY---TSGTF-RTVLIAC
.:.:..:::. :... . . :.:::.:.:.: . :: . :. ..: . .: : :
NP_005 VPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQVVQGLLSETYLEAH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB5 NVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLG
. .:.:. . .: .... ... . .:....:: :.:: :.::. ::::.: ::.:
NP_005 RIVKMNKSEDDESGAGELTR-EELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVG
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB5 GVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVT
::... : .:::.::: :.:::.::::::: :. :::. :::::::::::::::
NP_005 GVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVL
370 380 390 400 410
390 400 410 420 430 440
pF1KB5 TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLN
:. .:: ::.::.::::.:: ::::::::.. ::::::::::: ..:::::: . ::
NP_005 RDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLN
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB5 ARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLR
::::.::::::.::::. .. .:: : .::::::::... :. : ..: ....:.
NP_005 ARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITY
480 490 500 510 520 530
510 520 530 540 550 560
pF1KB5 MHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMV
.: :...: . .: : :
NP_005 VH------------------------------QHSRQPPSQFEPLDMKL-----------
540 550
570 580 590 600 610 620
pF1KB5 SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIR
:..:: . . .:.. . : ::. : ..: . :.:.. :: :::: ...:
NP_005 ----MRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATYTS---ARTLLAILR
560 570 580 590 600 610
630 640 650 660 670 680
pF1KB5 LATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQE
:.:: :. :: .:. .:..::..:.... : : .: . :..
NP_005 LSTALARLRMVDVVEKEDVNEAIRLMEMS--KDSLLGDKGQTARTQRPADVIFATVRELV
620 630 640 650 660
690 700 710 720 730 740
pF1KB5 DQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESR
NP_005 SGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV
670 680 690 700 710
>>XP_005250405 (OMIM: 600592) PREDICTED: DNA replication (612 aa)
initn: 866 init1: 780 opt: 1011 Z-score: 707.1 bits: 141.3 E(85289): 1.2e-32
Smith-Waterman score: 1079; 37.1% identity (64.3% similar) in 585 aa overlap (92-669:21-548)
70 80 90 100 110 120
pF1KB5 ANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFL
:. ...: . ..: ..: : . . .
XP_005 MMEQRSRDPGMVRSPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSV
10 20 30 40 50
130 140 150 160 170
pF1KB5 SCVVCVEGIVTKCSLVRPKVVRSVHYCPAT-KKTIERRYSD-LTTLVAFPSSSVYPTKDE
. .: :.::::. : :.::.: ... : .: . : . :. ::. ...
XP_005 GKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSG
60 70 80 90 100 110
180 190 200 210 220 230
pF1KB5 ENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVG
:.:. : : . : . .:: ...:.:..:::. :... . . :.:::.:.:.:
XP_005 GRLYLQTR-G-SRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTG
120 130 140 150 160
240 250 260 270 280 290
pF1KB5 TYRCLPGKKGGY---TSGTF-RTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDI
. :: . :. ..: . .: : : . .:.:. . .: .... ... . .:.
XP_005 IF--LPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTR-EELRQIAEEDF
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 FDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLL
...:: :.:: :.::. ::::.: ::.:::... : .:::.::: :.:::.:::::::
XP_005 YEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLL
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 RYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMS
:. :::. ::::::::::::::: :. .:: ::.::.::::.:: ::::::::.
XP_005 SYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMA
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB5 DMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSL
. ::::::::::: ..:::::: . ::::::.::::::.::::. .. .:: : .:
XP_005 EADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAAL
350 360 370 380 390 400
480 490 500 510 520 530
pF1KB5 LSRFDLLFIMLDQMDPEQDREISDHVLRMHRY-RAPGEQDGDAMPLGSAVDILATDDPNF
:::::::... :. : ..: ....:. .:.. : : :
XP_005 LSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQP--------P---------------
410 420 430 440
540 550 560 570 580 590
pF1KB5 SQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEY
:: . : .. :..:: . . .:.. . : ::. :
XP_005 SQFEPLDMKL-----------------------MRRYIAMCREKQPMVPESLADYITAAY
450 460 470
600 610 620 630 640 650
pF1KB5 SRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYF
..: . :.:.. :: :::: ...::.:: :. :: .:. .:..::..:....
XP_005 VEMRREAWASKDATYTS---ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS--
480 490 500 510 520 530
660 670 680 690 700 710
pF1KB5 KKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTE
: : .: . :..
XP_005 KDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDE
540 550 560 570 580 590
>>XP_016867706 (OMIM: 600592) PREDICTED: DNA replication (612 aa)
initn: 866 init1: 780 opt: 1011 Z-score: 707.1 bits: 141.3 E(85289): 1.2e-32
Smith-Waterman score: 1079; 37.1% identity (64.3% similar) in 585 aa overlap (92-669:21-548)
70 80 90 100 110 120
pF1KB5 ANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFL
:. ...: . ..: ..: : . . .
XP_016 MMEQRSRDPGMVRSPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSV
10 20 30 40 50
130 140 150 160 170
pF1KB5 SCVVCVEGIVTKCSLVRPKVVRSVHYCPAT-KKTIERRYSD-LTTLVAFPSSSVYPTKDE
. .: :.::::. : :.::.: ... : .: . : . :. ::. ...
XP_016 GKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSG
60 70 80 90 100 110
180 190 200 210 220 230
pF1KB5 ENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVG
:.:. : : . : . .:: ...:.:..:::. :... . . :.:::.:.:.:
XP_016 GRLYLQTR-G-SRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTG
120 130 140 150 160
240 250 260 270 280 290
pF1KB5 TYRCLPGKKGGY---TSGTF-RTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDI
. :: . :. ..: . .: : : . .:.:. . .: .... ... . .:.
XP_016 IF--LPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTR-EELRQIAEEDF
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 FDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLL
...:: :.:: :.::. ::::.: ::.:::... : .:::.::: :.:::.:::::::
XP_016 YEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLL
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 RYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMS
:. :::. ::::::::::::::: :. .:: ::.::.::::.:: ::::::::.
XP_016 SYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMA
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB5 DMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSL
. ::::::::::: ..:::::: . ::::::.::::::.::::. .. .:: : .:
XP_016 EADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAAL
350 360 370 380 390 400
480 490 500 510 520 530
pF1KB5 LSRFDLLFIMLDQMDPEQDREISDHVLRMHRY-RAPGEQDGDAMPLGSAVDILATDDPNF
:::::::... :. : ..: ....:. .:.. : : :
XP_016 LSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQP--------P---------------
410 420 430 440
540 550 560 570 580 590
pF1KB5 SQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEY
:: . : .. :..:: . . .:.. . : ::. :
XP_016 SQFEPLDMKL-----------------------MRRYIAMCREKQPMVPESLADYITAAY
450 460 470
600 610 620 630 640 650
pF1KB5 SRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYF
..: . :.:.. :: :::: ...::.:: :. :: .:. .:..::..:....
XP_016 VEMRREAWASKDATYTS---ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS--
480 490 500 510 520 530
660 670 680 690 700 710
pF1KB5 KKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTE
: : .: . :..
XP_016 KDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDE
540 550 560 570 580 590
>>NP_877577 (OMIM: 600592) DNA replication licensing fac (543 aa)
initn: 821 init1: 735 opt: 949 Z-score: 665.6 bits: 133.5 E(85289): 2.5e-30
Smith-Waterman score: 1017; 38.7% identity (65.2% similar) in 509 aa overlap (165-669:27-479)
140 150 160 170 180 190
pF1KB5 SLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYK
:. ::. ... :.:. : : .
NP_877 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTR-G-SRFI
10 20 30 40 50
200 210 220 230 240 250
pF1KB5 DHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGY---
: . .:: ...:.:..:::. :... . . :.:::.:.:.: . :: . :.
NP_877 KFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQV
60 70 80 90 100 110
260 270 280 290 300 310
pF1KB5 TSGTF-RTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGH
..: . .: : : . .:.:. . .: .... ... . .:....:: :.:: :.::
NP_877 VQGLLSETYLEAHRIVKMNKSEDDESGAGELTR-EELRQIAEEDFYEKLAASIAPEIYGH
120 130 140 150 160 170
320 330 340 350 360 370
pF1KB5 DYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTG
. ::::.: ::.:::... : .:::.::: :.:::.::::::: :. :::. :::
NP_877 EDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG
180 190 200 210 220 230
380 390 400 410 420 430
pF1KB5 RGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGR
:::::::::::: :. .:: ::.::.::::.:: ::::::::.. :::::::::::
NP_877 RGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQT
240 250 260 270 280 290
440 450 460 470 480 490
pF1KB5 VTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMD
..:::::: . ::::::.::::::.::::. .. .:: : .::::::::... :. :
NP_877 ISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPD
300 310 320 330 340 350
500 510 520 530 540 550
pF1KB5 PEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDN
..: ....:. .: :...: . .: :
NP_877 RDNDLRLAQHITYVH------------------------------QHSRQPPSQFEPLDM
360 370 380
560 570 580 590 600 610
pF1KB5 LLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART
: :..:: . . .:.. . : ::. : ..: . :.:.. :
NP_877 KL---------------MRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATYT
390 400 410 420
620 630 640 650 660 670
pF1KB5 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED
: :::: ...::.:: :. :: .:. .:..::..:.... : : .: . :..
NP_877 S---ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS--KDSLLGDKGQTARTQR
430 440 450 460 470 480
680 690 700 710 720 730
pF1KB5 ESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQE
NP_877 PADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRI
490 500 510 520 530 540
>>NP_001265524 (OMIM: 600592) DNA replication licensing (543 aa)
initn: 821 init1: 735 opt: 949 Z-score: 665.6 bits: 133.5 E(85289): 2.5e-30
Smith-Waterman score: 1017; 38.7% identity (65.2% similar) in 509 aa overlap (165-669:27-479)
140 150 160 170 180 190
pF1KB5 SLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYK
:. ::. ... :.:. : : .
NP_001 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTR-G-SRFI
10 20 30 40 50
200 210 220 230 240 250
pF1KB5 DHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGY---
: . .:: ...:.:..:::. :... . . :.:::.:.:.: . :: . :.
NP_001 KFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQV
60 70 80 90 100 110
260 270 280 290 300 310
pF1KB5 TSGTF-RTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGH
..: . .: : : . .:.:. . .: .... ... . .:....:: :.:: :.::
NP_001 VQGLLSETYLEAHRIVKMNKSEDDESGAGELTR-EELRQIAEEDFYEKLAASIAPEIYGH
120 130 140 150 160 170
320 330 340 350 360 370
pF1KB5 DYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTG
. ::::.: ::.:::... : .:::.::: :.:::.::::::: :. :::. :::
NP_001 EDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG
180 190 200 210 220 230
380 390 400 410 420 430
pF1KB5 RGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGR
:::::::::::: :. .:: ::.::.::::.:: ::::::::.. :::::::::::
NP_001 RGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQT
240 250 260 270 280 290
440 450 460 470 480 490
pF1KB5 VTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMD
..:::::: . ::::::.::::::.::::. .. .:: : .::::::::... :. :
NP_001 ISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPD
300 310 320 330 340 350
500 510 520 530 540 550
pF1KB5 PEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDN
..: ....:. .: :...: . .: :
NP_001 RDNDLRLAQHITYVH------------------------------QHSRQPPSQFEPLDM
360 370 380
560 570 580 590 600 610
pF1KB5 LLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART
: :..:: . . .:.. . : ::. : ..: . :.:.. :
NP_001 KL---------------MRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATYT
390 400 410 420
620 630 640 650 660 670
pF1KB5 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED
: :::: ...::.:: :. :: .:. .:..::..:.... : : .: . :..
NP_001 S---ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS--KDSLLGDKGQTARTQR
430 440 450 460 470 480
680 690 700 710 720 730
pF1KB5 ESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQE
NP_001 PADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRI
490 500 510 520 530 540
>>XP_006724305 (OMIM: 602696) PREDICTED: DNA replication (732 aa)
initn: 868 init1: 625 opt: 856 Z-score: 600.4 bits: 121.8 E(85289): 1.1e-26
Smith-Waterman score: 995; 31.3% identity (58.1% similar) in 718 aa overlap (3-690:17-682)
10 20 30 40
pF1KB5 MAGTVVLDDVELREAQ--RDYLDFLDDEE---DQGIYQSKVRELIS
: . :. . :..: : . .:: . . :. . : :. ..
XP_006 MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK
10 20 30 40 50 60
50 60 70 80 90
pF1KB5 DN----QYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALK---DFVASIDATYAKQ
. .: . :...:: .: :. : .. :.: ...: : : :. . .
XP_006 RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 YEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKT
... : :... .. : :.: : ..: .: . ::. : :: :..: : . ..:
XP_006 LQDIQVMLKSD--ASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNT
130 140 150 160 170
160 170 180 190 200 210
pF1KB5 IER-RYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYK---DHQTITIQEMPEKAPA
. . :.: . . . ::. . . : ::. .::.:. .:
XP_006 LTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPH
180 190 200 210 220 230
220 230 240 250 260
pF1KB5 GQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRC----LPGKKG------GYTSGTFRTVL
:..:: ... : : ::. ::.:: ..: : : ..: : :. .:..
XP_006 GEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLG
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB5 IACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCL
: .. ... . : .. ...... .... ..::.:::: : .:::: ::
XP_006 IQVDTDGSGRSFAGAVSPQEEEEFRRLAAL--PNVYEVISKSIAPSIFGGTDMKKAIACL
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB5 LLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTA
:.:: .. : .: :::::.:..:::..::::::..: .: .. :.:.:::..::::
XP_006 LFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTA
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB5 AVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHA
.: : . . .:.::::::: ::::::::::: . ::.::::.::: ..:::::: .
XP_006 SVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITT
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB5 RLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDH
::.::::::::: :.::.:. : .:: .. ..:::::..::. :. . :.: .. :
XP_006 TLNSRCSVLAAANSVFGRWDETKGE-DNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKH
480 490 500 510 520 530
510 520 530 540 550 560
pF1KB5 VLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKE
:. .: :. :. .:: : . .:
XP_006 VITLH------------------VSALT------------QTQAVEGEIDL---------
540 550
570 580 590 600 610
pF1KB5 KMVSAAFMKKYIHVAKI-IKPVLTQESATYIAEEYSRLRS---QDSMSSDTARTSPVTAR
: .::.: .. : :. :.: . ..: .:: : .:: . :.:.:
XP_006 -----AKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVR
560 570 580 590 600 610
620 630 640 650 660 670
pF1KB5 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETED
::...:.: : .: ... . :.:::..: : . . .: . . : . ::
XP_006 QLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAAL---SGTLSGVEGFTSQED
620 630 640 650 660
680 690 700 710 720 730
pF1KB5 EEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQK
.: :. ... ::.
XP_006 QEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQLSLLSGQAKASETETDRDRDERQTELE
670 680 690 700 710 720
>>NP_006730 (OMIM: 602696) DNA replication licensing fac (734 aa)
initn: 868 init1: 625 opt: 856 Z-score: 600.3 bits: 121.8 E(85289): 1.1e-26
Smith-Waterman score: 995; 31.3% identity (58.1% similar) in 718 aa overlap (3-690:17-682)
10 20 30 40
pF1KB5 MAGTVVLDDVELREAQ--RDYLDFLDDEE---DQGIYQSKVRELIS
: . :. . :..: : . .:: . . :. . : :. ..
NP_006 MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK
10 20 30 40 50 60
50 60 70 80 90
pF1KB5 DN----QYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALK---DFVASIDATYAKQ
. .: . :...:: .: :. : .. :.: ...: : : :. . .
NP_006 RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 YEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKT
... : :... .. : :.: : ..: .: . ::. : :: :..: : . ..:
NP_006 LQDIQVMLKSD--ASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNT
130 140 150 160 170
160 170 180 190 200 210
pF1KB5 IER-RYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYK---DHQTITIQEMPEKAPA
. . :.: . . . ::. . . : ::. .::.:. .:
NP_006 LTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPH
180 190 200 210 220 230
220 230 240 250 260
pF1KB5 GQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRC----LPGKKG------GYTSGTFRTVL
:..:: ... : : ::. ::.:: ..: : : ..: : :. .:..
NP_006 GEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLG
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB5 IACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCL
: .. ... . : .. ...... .... ..::.:::: : .:::: ::
NP_006 IQVDTDGSGRSFAGAVSPQEEEEFRRLAAL--PNVYEVISKSIAPSIFGGTDMKKAIACL
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB5 LLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTA
:.:: .. : .: :::::.:..:::..::::::..: .: .. :.:.:::..::::
NP_006 LFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTA
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB5 AVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHA
.: : . . .:.::::::: ::::::::::: . ::.::::.::: ..:::::: .
NP_006 SVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITT
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB5 RLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDH
::.::::::::: :.::.:. : .:: .. ..:::::..::. :. . :.: .. :
NP_006 TLNSRCSVLAAANSVFGRWDETKGE-DNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKH
480 490 500 510 520 530
510 520 530 540 550 560
pF1KB5 VLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKE
:. .: :. :. .:: : . .:
NP_006 VITLH------------------VSALT------------QTQAVEGEIDL---------
540 550
570 580 590 600 610
pF1KB5 KMVSAAFMKKYIHVAKI-IKPVLTQESATYIAEEYSRLRS---QDSMSSDTARTSPVTAR
: .::.: .. : :. :.: . ..: .:: : .:: . :.:.:
NP_006 -----AKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVR
560 570 580 590 600 610
620 630 640 650 660 670
pF1KB5 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETED
::...:.: : .: ... . :.:::..: : . . .: . . : . ::
NP_006 QLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAAL---SGTLSGVEGFTSQED
620 630 640 650 660
680 690 700 710 720 730
pF1KB5 EEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQK
.: :. ... ::.
NP_006 QEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRK
670 680 690 700 710 720
808 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:15:12 2016 done: Sat Nov 5 16:15:14 2016
Total Scan time: 13.300 Total Display time: 0.210
Function used was FASTA [36.3.4 Apr, 2011]