Result of FASTA (omim) for
pF1KB5741
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5741, 799 aa
1>>>pF1KB5741 799 - 799 aa - 799 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8691+/-0.000596; mu= 14.7336+/- 0.036
mean_var=250.2189+/-49.795, 0's: 0 Z-trim(113.2): 298 B-trim: 50 in 1/54
Lambda= 0.081080
statistics sampled from 22082 (22420) to 22082 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.263), width: 16
Scan time: 11.960
The best scores are: opt bits E(85289)
NP_002204 (OMIM: 147561) integrin beta-5 precursor ( 799) 5624 672.8 1.6e-192
XP_016861841 (OMIM: 147561) PREDICTED: integrin be ( 691) 4863 583.7 9.1e-166
XP_016861840 (OMIM: 147561) PREDICTED: integrin be ( 691) 4863 583.7 9.1e-166
XP_016861842 (OMIM: 147561) PREDICTED: integrin be ( 691) 4863 583.7 9.1e-166
NP_000203 (OMIM: 173470,187800,273800,608446) inte ( 788) 3122 380.1 2e-104
XP_016861844 (OMIM: 147561) PREDICTED: integrin be ( 661) 3085 375.7 3.6e-103
XP_005247493 (OMIM: 147561) PREDICTED: integrin be ( 769) 3085 375.8 3.9e-103
XP_016861843 (OMIM: 147561) PREDICTED: integrin be ( 683) 3076 374.7 7.6e-103
XP_006713693 (OMIM: 147561) PREDICTED: integrin be ( 754) 2762 338.0 9.2e-92
NP_000879 (OMIM: 147558,616221) integrin beta-6 is ( 788) 2746 336.2 3.5e-91
NP_001269282 (OMIM: 147558,616221) integrin beta-6 ( 788) 2746 336.2 3.5e-91
NP_001269317 (OMIM: 147558,616221) integrin beta-6 ( 746) 2609 320.1 2.2e-86
NP_001269318 (OMIM: 147558,616221) integrin beta-6 ( 715) 2445 300.9 1.3e-80
NP_001269283 (OMIM: 147558,616221) integrin beta-6 ( 693) 2439 300.2 2.1e-80
NP_001269319 (OMIM: 147558,616221) integrin beta-6 ( 650) 2329 287.3 1.5e-76
NP_391988 (OMIM: 135630) integrin beta-1 isoform 1 ( 801) 2314 285.6 5.7e-76
NP_002202 (OMIM: 135630) integrin beta-1 isoform 1 ( 798) 2309 285.0 8.5e-76
NP_596867 (OMIM: 135630) integrin beta-1 isoform 1 ( 798) 2309 285.0 8.5e-76
NP_001269284 (OMIM: 147558,616221) integrin beta-6 ( 681) 2050 254.6 1e-66
XP_005268909 (OMIM: 147559) PREDICTED: integrin be ( 798) 2043 253.9 2e-66
XP_005268908 (OMIM: 147559) PREDICTED: integrin be ( 798) 2043 253.9 2e-66
NP_000880 (OMIM: 147559) integrin beta-7 precursor ( 798) 2043 253.9 2e-66
XP_006719439 (OMIM: 147559) PREDICTED: integrin be ( 782) 1993 248.1 1.1e-64
NP_001120963 (OMIM: 116920,600065) integrin beta-2 ( 769) 1803 225.8 5.5e-58
NP_000202 (OMIM: 116920,600065) integrin beta-2 is ( 769) 1803 225.8 5.5e-58
NP_001290167 (OMIM: 116920,600065) integrin beta-2 ( 700) 1736 217.9 1.2e-55
XP_006724064 (OMIM: 116920,600065) PREDICTED: inte ( 700) 1736 217.9 1.2e-55
XP_016883830 (OMIM: 116920,600065) PREDICTED: inte ( 700) 1736 217.9 1.2e-55
XP_011513696 (OMIM: 604160) PREDICTED: integrin be ( 758) 1629 205.5 7.3e-52
XP_011513695 (OMIM: 604160) PREDICTED: integrin be ( 761) 1629 205.5 7.3e-52
NP_002205 (OMIM: 604160) integrin beta-8 precursor ( 769) 1629 205.5 7.3e-52
XP_016867667 (OMIM: 604160) PREDICTED: integrin be ( 769) 1629 205.5 7.3e-52
XP_016867668 (OMIM: 604160) PREDICTED: integrin be ( 769) 1629 205.5 7.3e-52
XP_016867669 (OMIM: 604160) PREDICTED: integrin be ( 634) 1556 196.8 2.4e-49
XP_016867670 (OMIM: 604160) PREDICTED: integrin be ( 634) 1556 196.8 2.4e-49
XP_016867671 (OMIM: 604160) PREDICTED: integrin be ( 634) 1556 196.8 2.4e-49
XP_016867672 (OMIM: 604160) PREDICTED: integrin be ( 634) 1556 196.8 2.4e-49
XP_011513698 (OMIM: 604160) PREDICTED: integrin be ( 634) 1556 196.8 2.4e-49
NP_001308052 (OMIM: 131800,147557,226650,226730) i (1752) 1475 188.0 3.1e-46
NP_001005731 (OMIM: 131800,147557,226650,226730) i (1752) 1475 188.0 3.1e-46
XP_006721933 (OMIM: 131800,147557,226650,226730) P (1787) 1475 188.0 3.1e-46
NP_001005619 (OMIM: 131800,147557,226650,226730) i (1805) 1475 188.0 3.1e-46
XP_011523053 (OMIM: 131800,147557,226650,226730) P (1807) 1475 188.0 3.1e-46
NP_000204 (OMIM: 131800,147557,226650,226730) inte (1822) 1475 188.0 3.1e-46
XP_006721931 (OMIM: 131800,147557,226650,226730) P (1840) 1475 188.0 3.2e-46
XP_006721930 (OMIM: 131800,147557,226650,226730) P (1857) 1475 188.0 3.2e-46
XP_005257366 (OMIM: 131800,147557,226650,226730) P (1875) 1475 188.0 3.2e-46
XP_005257368 (OMIM: 131800,147557,226650,226730) P (1875) 1475 188.0 3.2e-46
XP_006721929 (OMIM: 131800,147557,226650,226730) P (1910) 1475 188.0 3.2e-46
NP_001258683 (OMIM: 604234) integrin beta-like pro ( 353) 476 70.1 1.9e-11
>>NP_002204 (OMIM: 147561) integrin beta-5 precursor [Ho (799 aa)
initn: 5624 init1: 5624 opt: 5624 Z-score: 3577.5 bits: 672.8 E(85289): 1.6e-192
Smith-Waterman score: 5624; 100.0% identity (100.0% similar) in 799 aa overlap (1-799:1-799)
10 20 30 40 50 60
pF1KB5 MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 TSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 DGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 TYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 GKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 ICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 CRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 MTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
730 740 750 760 770 780
790
pF1KB5 HTVDFTFNKFNKSYNGTVD
:::::::::::::::::::
NP_002 HTVDFTFNKFNKSYNGTVD
790
>>XP_016861841 (OMIM: 147561) PREDICTED: integrin beta-5 (691 aa)
initn: 4863 init1: 4863 opt: 4863 Z-score: 3097.0 bits: 583.7 E(85289): 9.1e-166
Smith-Waterman score: 4863; 100.0% identity (100.0% similar) in 691 aa overlap (109-799:1-691)
80 90 100 110 120 130
pF1KB5 IESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRPGDKTTFQLQVRQVEDYPV
::::::::::::::::::::::::::::::
XP_016 MTPQEIAVNLRPGDKTTFQLQVRQVEDYPV
10 20 30
140 150 160 170 180 190
pF1KB5 DLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQ
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 TNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAV
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 CKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPS
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 LALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSI
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 RSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSLEARSCPSRHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSLEARSCPSRHT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 EHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRC
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB5 ECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARN
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB5 KGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEP
460 470 480 490 500 510
620 630 640 650 660 670
pF1KB5 GAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQE
520 530 540 550 560 570
680 690 700 710 720 730
pF1KB5 AVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLAL
580 590 600 610 620 630
740 750 760 770 780 790
pF1KB5 LAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTV
640 650 660 670 680 690
pF1KB5 D
:
XP_016 D
>>XP_016861840 (OMIM: 147561) PREDICTED: integrin beta-5 (691 aa)
initn: 4863 init1: 4863 opt: 4863 Z-score: 3097.0 bits: 583.7 E(85289): 9.1e-166
Smith-Waterman score: 4863; 100.0% identity (100.0% similar) in 691 aa overlap (109-799:1-691)
80 90 100 110 120 130
pF1KB5 IESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRPGDKTTFQLQVRQVEDYPV
::::::::::::::::::::::::::::::
XP_016 MTPQEIAVNLRPGDKTTFQLQVRQVEDYPV
10 20 30
140 150 160 170 180 190
pF1KB5 DLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQ
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 TNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAV
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 CKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPS
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 LALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSI
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 RSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSLEARSCPSRHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSLEARSCPSRHT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 EHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRC
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB5 ECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARN
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB5 KGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEP
460 470 480 490 500 510
620 630 640 650 660 670
pF1KB5 GAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQE
520 530 540 550 560 570
680 690 700 710 720 730
pF1KB5 AVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLAL
580 590 600 610 620 630
740 750 760 770 780 790
pF1KB5 LAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTV
640 650 660 670 680 690
pF1KB5 D
:
XP_016 D
>>XP_016861842 (OMIM: 147561) PREDICTED: integrin beta-5 (691 aa)
initn: 4863 init1: 4863 opt: 4863 Z-score: 3097.0 bits: 583.7 E(85289): 9.1e-166
Smith-Waterman score: 4863; 100.0% identity (100.0% similar) in 691 aa overlap (109-799:1-691)
80 90 100 110 120 130
pF1KB5 IESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRPGDKTTFQLQVRQVEDYPV
::::::::::::::::::::::::::::::
XP_016 MTPQEIAVNLRPGDKTTFQLQVRQVEDYPV
10 20 30
140 150 160 170 180 190
pF1KB5 DLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQ
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 TNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAV
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 CKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPS
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 LALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSI
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 RSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSLEARSCPSRHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSLEARSCPSRHT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 EHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRC
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB5 ECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARN
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB5 KGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEP
460 470 480 490 500 510
620 630 640 650 660 670
pF1KB5 GAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQE
520 530 540 550 560 570
680 690 700 710 720 730
pF1KB5 AVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLAL
580 590 600 610 620 630
740 750 760 770 780 790
pF1KB5 LAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTV
640 650 660 670 680 690
pF1KB5 D
:
XP_016 D
>>NP_000203 (OMIM: 173470,187800,273800,608446) integrin (788 aa)
initn: 2942 init1: 2122 opt: 3122 Z-score: 1995.8 bits: 380.1 E(85289): 2e-104
Smith-Waterman score: 3122; 55.7% identity (78.8% similar) in 788 aa overlap (2-782:5-781)
10 20 30 40 50
pF1KB5 MPRAPAPLYACLLGLCALLPR-LAGLNICTSGSATSCEECLLIHPKCAWCSKE--DF
:: : ::.: .:.: :: ..: ::::. ...::..:: . : ::::: : .
NP_000 MRARPR-PRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPL
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 GSPRSITSRCDLRANLVKNGCGGE-IESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQE
:::: :::. ::.:..:. : :: :.: .::.. :::.::::... .: :..::.
NP_000 GSPR-----CDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSS-QVTQVSPQR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 IAVNLRPGDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTS
::. ::: :. .:..:::::::::::.::::::: :::::: .:..:::::: .::::::
NP_000 IALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 NFRLGFGSFVDKDISPFSY-TAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNE
:.:.:::.:::: .::. : . :. ::: : . .:.: ::..:.: :::.: :::
NP_000 NLRIGFGAFVDKPVSPYMYISPPEALENPC--YDMKTTCLPMFGYKHVLTLTDQVTRFNE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 EVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGL
::.:: ::::::::::::::..::.:: ::::::.:: :::::::: ::::::.:.:.
NP_000 EVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 VQPHDGQCHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALI
:::.:::::.. :.:.::. ::::::.:. :::...:::::::::.: ::.:.. ::
NP_000 VQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 PGTTVEILDGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRK
::::: .:. ::.:..:::..::..::::::: : : ::.:.: :.::: .. :: ..
NP_000 PGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKS
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 CEGLKIGDTASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPN
: :::::::.:: . ..:.:: .. :. :...::::.::: : ::..: :.:.. :::
NP_000 CMGLKIGDTVSFSIEAKVRGCP-QEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPN
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 SARCN-GSGTYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCN
: ::: :.::. ::.:.:.::.::..:::.. . . :. : ::.:.:: ::.: :.
NP_000 SHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCG
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB5 QCSCFESEFGKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDI
:: : :.:::: : .::::.:::.: :: .:::::.: ::.: : . . : :::.:
NP_000 QCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRT
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB5 STCRGRDGQICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGK
.:: . .: .:: ::.: ::.: : .::..:. :::::::::::. :..:::: . :
NP_000 DTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGA
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB5 -PDNQTCHSLCRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLR
:..::. ::::. . : . ..:: : ::. :::. : : : :::: : :..
NP_000 LHDENTCNRYCRDEIES-VKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVE
660 670 680 690 700
720 730 740 750 760 770
pF1KB5 EPECGNTPNAMTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMAS
:::: . :. ...::.:.:.:::.::: : :::::.:::::.:::::. ::.::... :.
NP_000 EPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTAN
710 720 730 740 750 760
780 790
pF1KB5 NPLYRKPISTHTVDFTFNKFNKSYNGTVD
::::.. :: :
NP_000 NPLYKEATSTFTNITYRGT
770 780
>>XP_016861844 (OMIM: 147561) PREDICTED: integrin beta-5 (661 aa)
initn: 3082 init1: 3082 opt: 3085 Z-score: 1973.2 bits: 375.7 E(85289): 3.6e-103
Smith-Waterman score: 4608; 95.7% identity (95.7% similar) in 691 aa overlap (109-799:1-661)
80 90 100 110 120 130
pF1KB5 IESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRPGDKTTFQLQVRQVEDYPV
::::::::::::::::::::::::::::::
XP_016 MTPQEIAVNLRPGDKTTFQLQVRQVEDYPV
10 20 30
140 150 160 170 180 190
pF1KB5 DLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQ
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 TNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAV
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 CKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPS
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 LALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSI
:::::::::::::::::::::::::::: ::
XP_016 LALLGEKLAENNINLIFAVTKNHYMLYK------------------------------SI
220 230 240
380 390 400 410 420 430
pF1KB5 RSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSLEARSCPSRHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSLEARSCPSRHT
250 260 270 280 290 300
440 450 460 470 480 490
pF1KB5 EHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRC
310 320 330 340 350 360
500 510 520 530 540 550
pF1KB5 ECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARN
370 380 390 400 410 420
560 570 580 590 600 610
pF1KB5 KGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEP
430 440 450 460 470 480
620 630 640 650 660 670
pF1KB5 GAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQE
490 500 510 520 530 540
680 690 700 710 720 730
pF1KB5 AVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLAL
550 560 570 580 590 600
740 750 760 770 780 790
pF1KB5 LAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTV
610 620 630 640 650 660
pF1KB5 D
:
XP_016 D
>>XP_005247493 (OMIM: 147561) PREDICTED: integrin beta-5 (769 aa)
initn: 3082 init1: 3082 opt: 3085 Z-score: 1972.5 bits: 375.8 E(85289): 3.9e-103
Smith-Waterman score: 5369; 96.2% identity (96.2% similar) in 799 aa overlap (1-799:1-769)
10 20 30 40 50 60
pF1KB5 MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 TSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEIL
::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYK--------------
310 320 330 340
370 380 390 400 410 420
pF1KB5 DGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD
::::::::::::::::::::::::::::::::::::::::::::
XP_005 ----------------SIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD
350 360 370 380 390
430 440 450 460 470 480
pF1KB5 TASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSG
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB5 TYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEF
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB5 GKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB5 ICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSL
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB5 CRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNA
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB5 MTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
700 710 720 730 740 750
790
pF1KB5 HTVDFTFNKFNKSYNGTVD
:::::::::::::::::::
XP_005 HTVDFTFNKFNKSYNGTVD
760
>>XP_016861843 (OMIM: 147561) PREDICTED: integrin beta-5 (683 aa)
initn: 4846 init1: 3074 opt: 3076 Z-score: 1967.3 bits: 374.7 E(85289): 7.6e-103
Smith-Waterman score: 4618; 85.5% identity (85.5% similar) in 799 aa overlap (1-799:1-683)
10 20 30 40 50 60
pF1KB5 MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 TSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
::::::::::::::::::::
XP_016 RNRDAPEGGFDAVLQAAVCK----------------------------------------
250 260
310 320 330 340 350 360
pF1KB5 HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEIL
XP_016 ------------------------------------------------------------
370 380 390 400 410 420
pF1KB5 DGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD
::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----------------SIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD
270 280 290 300
430 440 450 460 470 480
pF1KB5 TASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSG
310 320 330 340 350 360
490 500 510 520 530 540
pF1KB5 TYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEF
370 380 390 400 410 420
550 560 570 580 590 600
pF1KB5 GKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQ
430 440 450 460 470 480
610 620 630 640 650 660
pF1KB5 ICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSL
490 500 510 520 530 540
670 680 690 700 710 720
pF1KB5 CRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNA
550 560 570 580 590 600
730 740 750 760 770 780
pF1KB5 MTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
610 620 630 640 650 660
790
pF1KB5 HTVDFTFNKFNKSYNGTVD
:::::::::::::::::::
XP_016 HTVDFTFNKFNKSYNGTVD
670 680
>>XP_006713693 (OMIM: 147561) PREDICTED: integrin beta-5 (754 aa)
initn: 2762 init1: 2762 opt: 2762 Z-score: 1768.4 bits: 338.0 E(85289): 9.2e-92
Smith-Waterman score: 5212; 94.4% identity (94.4% similar) in 799 aa overlap (1-799:1-754)
10 20 30 40 50 60
pF1KB5 MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 TSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 DGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD
::::::::::::::::
XP_006 DGDSKNIIQLIINAYN--------------------------------------------
370
430 440 450 460 470 480
pF1KB5 TASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 -ASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSG
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB5 TYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEF
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB5 GKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQ
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB5 ICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSL
560 570 580 590 600 610
670 680 690 700 710 720
pF1KB5 CRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNA
620 630 640 650 660 670
730 740 750 760 770 780
pF1KB5 MTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
680 690 700 710 720 730
790
pF1KB5 HTVDFTFNKFNKSYNGTVD
:::::::::::::::::::
XP_006 HTVDFTFNKFNKSYNGTVD
740 750
>>NP_000879 (OMIM: 147558,616221) integrin beta-6 isofor (788 aa)
initn: 2627 init1: 853 opt: 2746 Z-score: 1758.1 bits: 336.2 E(85289): 3.5e-91
Smith-Waterman score: 2746; 49.5% identity (76.9% similar) in 757 aa overlap (28-780:23-768)
10 20 30 40 50 60
pF1KB5 MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSI
:. :.: .::.:::: :.::::..:.: : ..
NP_000 MGIELLCLFFLFLGRNDHVQGGCALGGAETCEDCLLIGPQCAWCAQENFTHPSGV
10 20 30 40 50
70 80 90 100 110
pF1KB5 TSRCDLRANLVKNGCG-GEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLR
::: :::. .:: . ::.:.:. ..:.. ::: : . . :..:..:: . ..::
NP_000 GERCDTPANLLAKGCQLNFIENPVSQVEILKNKPLSV-GRQKNSSDIVQIAPQSLILKLR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PGDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGF
:: :.:..:::.:::::::::::::: :: :::..:. ::..:..:: ::::::::::
NP_000 PGGAQTLQVHVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 GSFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRV
::::.: .::: :.:. .::: . : :.:.:::.:.::::. .. ::: :..:..
NP_000 GSFVEKPVSPFVKTTPEEIANPCSSIPYF--CLPTFGFKHILPLTNDAERFNEIVKNQKI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 SRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQ
: : :.:::::::..::::::::::::.:.::::::..: :...:.::.:.: :.::
NP_000 SANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 CHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEI
:::. :::. :. ..::... : .::..::. ::::::... ::.:.. ::::.:: .
NP_000 CHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 LDGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIG
:. :: ::.::::.::. .::.::: : . : ::: ::: :..:. . :.:: .:.:
NP_000 LQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTAICNNGTLFQHQKKCSHMKVG
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 DTASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCN-G
::::: :... : :...:.. ..:::. :.::. :. .:.: :. .: ::..:. :
NP_000 DTASFSVTVNIPHCE-RRSRHII-IKPVGLGDALELLVSPECNCDCQKEVEVNSSKCHHG
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 SGTYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFES
.:.. ::.: : ::..: :::: ::.. . . :.:: .: ::::::: :.:: : :
NP_000 NGSFQCGVCACHPGHMGPRCEC--GEDM-LSTDSCKEAPDHPSCSGRGDCYCGQCICHLS
480 490 500 510 520
540 550 560 570 580 590
pF1KB5 EFGKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRD
.:.::::.:.::::::.:.::.::.:.:.: :::: :..:. :. :::.:. ..: ..:
NP_000 PYGNIYGPYCQCDNFSCVRHKGLLCGGNGDCDCGECVCRSGWTGEYCNCTTSTDSCVSED
530 540 550 560 570 580
600 610 620 630 640 650
pF1KB5 GQICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCH
: .:: :: :.::.: ::.::: : ::.:::: : :..::.:.:: : .:. .. :
NP_000 GVLCSGRGDCVCGKCVCTNPGASGPTCERCPTCGDPCNSKRSCIECHLSAAGQAREE-CV
590 600 610 620 630 640
660 670 680 690 700 710
pF1KB5 SLCR--DEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGN
. :. .:. . . :: .: : . ..:.. : . ::. . . : .: .
NP_000 DKCKLAGATISEEEDFSKDG--SVSCSLQGENECLITFLITTDNEGKTIIHSINEKDCPK
650 660 670 680 690 700
720 730 740 750 760 770
pF1KB5 TPNAMTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRK
:: :.:.: .:::.:..:: ::::::..:::.: :::..:::.:... ..:::::
NP_000 PPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRG
710 720 730 740 750 760
780 790
pF1KB5 PISTHTVDFTFNKFNKSYNGTVD
::
NP_000 STSTFKNVTYKHREKQKVDLSTDC
770 780
799 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:14:35 2016 done: Sat Nov 5 21:14:36 2016
Total Scan time: 11.960 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]