Result of FASTA (omim) for
pF1KB5695
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5695, 636 aa
1>>>pF1KB5695 636 - 636 aa - 636 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6826+/-0.000648; mu= 2.9091+/- 0.041
mean_var=409.0303+/-89.657, 0's: 0 Z-trim(117.1): 178 B-trim: 3336 in 2/49
Lambda= 0.063416
statistics sampled from 28509 (28721) to 28509 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.337), width: 16
Scan time: 7.720
The best scores are: opt bits E(85289)
NP_002559 (OMIM: 604679) polyadenylate-binding pro ( 636) 4211 400.3 1.1e-110
XP_005250918 (OMIM: 604679) PREDICTED: polyadenyla ( 636) 4211 400.3 1.1e-110
NP_112241 (OMIM: 604680) polyadenylate-binding pro ( 631) 3818 364.3 7.2e-100
NP_001129126 (OMIM: 603407) polyadenylate-binding ( 631) 3255 312.8 2.3e-84
NP_003810 (OMIM: 603407) polyadenylate-binding pro ( 644) 2648 257.3 1.2e-67
NP_001129125 (OMIM: 603407) polyadenylate-binding ( 660) 2646 257.1 1.4e-67
NP_543022 (OMIM: 300407) polyadenylate-binding pro ( 382) 1606 161.7 4.4e-39
NP_005841 (OMIM: 154400,605593) splicing factor 3B ( 424) 402 51.6 6.8e-06
NP_001310894 (OMIM: 603413) nucleolysin TIAR isofo ( 252) 295 41.5 0.0043
NP_001310893 (OMIM: 603413) nucleolysin TIAR isofo ( 252) 295 41.5 0.0043
XP_016872095 (OMIM: 603413) PREDICTED: nucleolysin ( 252) 295 41.5 0.0043
NP_001310896 (OMIM: 603413) nucleolysin TIAR isofo ( 252) 295 41.5 0.0043
NP_001164666 (OMIM: 601673) ELAV-like protein 2 is ( 346) 297 41.9 0.0046
XP_016869914 (OMIM: 601673) PREDICTED: ELAV-like p ( 346) 297 41.9 0.0046
NP_001164668 (OMIM: 601673) ELAV-like protein 2 is ( 346) 297 41.9 0.0046
XP_016869913 (OMIM: 601673) PREDICTED: ELAV-like p ( 346) 297 41.9 0.0046
XP_016869908 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 297 41.9 0.0048
NP_004423 (OMIM: 601673) ELAV-like protein 2 isofo ( 359) 297 41.9 0.0048
XP_016869911 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 297 41.9 0.0048
XP_016869910 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 297 41.9 0.0048
XP_016869912 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 297 41.9 0.0048
XP_016869909 (OMIM: 601673) PREDICTED: ELAV-like p ( 359) 297 41.9 0.0048
XP_005251450 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 297 41.9 0.0048
XP_011516087 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 297 41.9 0.0048
XP_011516086 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 297 41.9 0.0048
XP_011516088 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 297 41.9 0.0048
XP_016869907 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 297 41.9 0.0048
XP_005251452 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 297 41.9 0.0048
XP_005251451 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 297 41.9 0.0048
XP_006716799 (OMIM: 601673) PREDICTED: ELAV-like p ( 360) 297 41.9 0.0048
XP_016869906 (OMIM: 601673) PREDICTED: ELAV-like p ( 373) 297 41.9 0.0049
XP_011516085 (OMIM: 601673) PREDICTED: ELAV-like p ( 374) 297 41.9 0.0049
XP_016869905 (OMIM: 601673) PREDICTED: ELAV-like p ( 375) 297 41.9 0.0049
XP_011516079 (OMIM: 601673) PREDICTED: ELAV-like p ( 375) 297 41.9 0.0049
XP_016869904 (OMIM: 601673) PREDICTED: ELAV-like p ( 376) 297 41.9 0.0049
XP_011516078 (OMIM: 601673) PREDICTED: ELAV-like p ( 376) 297 41.9 0.0049
XP_016869903 (OMIM: 601673) PREDICTED: ELAV-like p ( 387) 297 41.9 0.005
XP_016869902 (OMIM: 601673) PREDICTED: ELAV-like p ( 387) 297 41.9 0.005
XP_011516076 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 297 41.9 0.005
XP_016869898 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 297 41.9 0.005
XP_016869899 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 297 41.9 0.005
XP_016869901 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 297 41.9 0.005
XP_016869900 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 297 41.9 0.005
XP_016869897 (OMIM: 601673) PREDICTED: ELAV-like p ( 388) 297 41.9 0.005
XP_006716797 (OMIM: 601673) PREDICTED: ELAV-like p ( 389) 297 41.9 0.005
XP_011516082 (OMIM: 601673) PREDICTED: ELAV-like p ( 389) 297 41.9 0.005
XP_011516081 (OMIM: 601673) PREDICTED: ELAV-like p ( 389) 297 41.9 0.005
XP_006716798 (OMIM: 601673) PREDICTED: ELAV-like p ( 389) 297 41.9 0.005
XP_011516080 (OMIM: 601673) PREDICTED: ELAV-like p ( 392) 297 41.9 0.005
NP_001311138 (OMIM: 168360) ELAV-like protein 4 is ( 352) 294 41.6 0.0057
>>NP_002559 (OMIM: 604679) polyadenylate-binding protein (636 aa)
initn: 4211 init1: 4211 opt: 4211 Z-score: 2108.3 bits: 400.3 E(85289): 1.1e-110
Smith-Waterman score: 4211; 100.0% identity (100.0% similar) in 636 aa overlap (1-636:1-636)
10 20 30 40 50 60
pF1KB5 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
550 560 570 580 590 600
610 620 630
pF1KB5 ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
::::::::::::::::::::::::::::::::::::
NP_002 ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
610 620 630
>>XP_005250918 (OMIM: 604679) PREDICTED: polyadenylate-b (636 aa)
initn: 4211 init1: 4211 opt: 4211 Z-score: 2108.3 bits: 400.3 E(85289): 1.1e-110
Smith-Waterman score: 4211; 100.0% identity (100.0% similar) in 636 aa overlap (1-636:1-636)
10 20 30 40 50 60
pF1KB5 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
550 560 570 580 590 600
610 620 630
pF1KB5 ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
::::::::::::::::::::::::::::::::::::
XP_005 ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
610 620 630
>>NP_112241 (OMIM: 604680) polyadenylate-binding protein (631 aa)
initn: 3248 init1: 2425 opt: 3818 Z-score: 1914.0 bits: 364.3 E(85289): 7.2e-100
Smith-Waterman score: 3818; 92.0% identity (95.9% similar) in 637 aa overlap (1-636:1-631)
10 20 30 40 50 60
pF1KB5 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
::::.:::: :::::::::::::::::::::::::::::::.:::.:: : .:::::::
NP_112 MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
. :::.:::::::::::::::::::::::::::::::::::.:::::::.::::::: :
NP_112 HTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
::::::::.::::::::::::::::::.:::::::.:::::::: ::::::.::::::::
NP_112 AFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKERE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 AELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
:::::::::::::::::::::::::::::::::::::: ::::::::::::: :::::::
NP_112 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
NP_112 LDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
::::::::::::::::.:::.::::::::::::: : ::::::::.:.:::::.:
NP_112 KPLYVALAQRKEERQAYLTNEYMQRMASVRAVPN------QRAPPSGYFMTAVPQTQNHA
370 380 390 400 410
430 440 450 460 470 480
pF1KB5 AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
:::::::::.::::::::::::::::::: :.::::.::: :::::::::::::::::::
NP_112 AYYPPSQIARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMSTQ
420 430 440 450 460 470
490 500 510 520 530
pF1KB5 RVANTSTQTMGPRPAAAAAAA-TPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHV
:::::::::.::::::::::: ::::::::.::::::::::::: :::::::::: ::::
NP_112 RVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHV
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB5 QGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLES
:::: :::: :::::::.:::::::::::::::::::::::::::::::::::::.::::
NP_112 QGQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLYMLES
540 550 560 570 580 590
600 610 620 630
pF1KB5 PESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
:::::::::::::::::::::::.:::::::::::::
NP_112 PESLRSKVDEAVAVLQAHQAKEATQKAVNSATGVPTV
600 610 620 630
>>NP_001129126 (OMIM: 603407) polyadenylate-binding prot (631 aa)
initn: 3011 init1: 2487 opt: 3255 Z-score: 1635.6 bits: 312.8 E(85289): 2.3e-84
Smith-Waterman score: 3255; 78.8% identity (90.8% similar) in 641 aa overlap (1-631:1-630)
10 20 30 40 50 60
pF1KB5 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
:: .: ::::::::::::: ::::::::::::::::.:::::::::::::::::::::::
NP_001 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
:::::::::::::::::::::.::::::::::::::::::.:::::::::::::::::::
NP_001 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
::::::::::::::::::::.::::::::::..:::::::::::::::::::::::::::
NP_001 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
:::::.::::::::::::::..::: ::.::..:: .:::::: : .::::::::::.:.
NP_001 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
::::.:::.::::::..:: :.:::::::::::.::::::::.::.::.::::::::.::
NP_001 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
::: ::::.:::::::::.:::::::.: :::::::::::::::::::::::::::::..
NP_001 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVP-NPVINPYQPAPPSGYFMAAIPQTQNR
::::::::::::::.::::::::::.:..::.: : ..: .::: .:::. :.::.:.:
NP_001 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAA-GGYFVPAVPQAQGR
370 380 390 400 410
420 430 440 450 460 470
pF1KB5 AAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRP-----ASSQVP
:: :.:.::.::.::: ::.::. ::.::.::: ..::: . . : :: .:
NP_001 PPYYTPNQLAQMRPNPRWQ-QGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLP
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 RVMSTQRVA-NTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQ
.::::. :..:...:: ::.:::.: :.: ::::..::.: : :: .
NP_001 T--TTQRVGVPTAVQNLAPR--AAVAAAAP--RAVAPYKYASSVRSP--HPAIQP-LQAP
480 490 500 510 520
540 550 560 570 580 590
pF1KB5 QPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSEL
::::::::::::::::::.:::::::::::::::::::.:: .:::::::::::::::::
NP_001 QPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSEL
530 540 550 560 570 580
600 610 620 630
pF1KB5 LHMLESPESLRSKVDEAVAVLQAHQAK-EAAQK--AVNSATGVPTV
::::::::::::::::::::::::.:: ::::: :: .::
NP_001 LHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS
590 600 610 620 630
>>NP_003810 (OMIM: 603407) polyadenylate-binding protein (644 aa)
initn: 3011 init1: 2487 opt: 2648 Z-score: 1335.4 bits: 257.3 E(85289): 1.2e-67
Smith-Waterman score: 3232; 77.2% identity (89.2% similar) in 650 aa overlap (1-631:1-643)
10 20 30 40 50 60
pF1KB5 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
:: .: ::::::::::::: ::::::::::::::::.:::::::::::::::::::::::
NP_003 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
:::::::::::::::::::::.::::::::::::::::::.:::::::::::::::::::
NP_003 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
::::::::::::::::::::.::::::::::..:::::::::::::::::::::::::::
NP_003 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
:::::.::::::::::::::..::: ::.::..:: .:::::: : .::::::::::.:.
NP_003 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
::::.:::.::::::..:: :.:::::::::::.::::::::.::.::.::::::::.::
NP_003 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
::: ::::.:::::::::.:::::::.: :::::::::::::::::::::::::::::..
NP_003 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVP-NPVINPYQPAPPSGYFMAAIPQTQNR
::::::::::::::.::::::::::.:..::.: : ..: .::: .:::. :.::.:.:
NP_003 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAA-GGYFVPAVPQAQGR
370 380 390 400 410
420 430 440 450 460 470
pF1KB5 AAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMS-
:: :.:.::.::.::: ::.::. ::.::.::: ..::: . . :..:. : ..
NP_003 PPYYTPNQLAQMRPNPRWQ-QGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAM
420 430 440 450 460 470
480 490 500 510 520
pF1KB5 -------TQRVANTSTQTMG-PR------PAAAAAAATPAVRTVPQYKYAAGVRNPQQHL
.:. . : :. : : : ::.:::.: :.: ::::..::.: :
NP_003 DFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAP--RAVAPYKYASSVRSP--HP
480 490 500 510 520 530
530 540 550 560 570 580
pF1KB5 NAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGM
:: . ::::::::::::::::::.:::::::::::::::::::.:: .::::::::
NP_003 AIQP-LQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGM
540 550 560 570 580 590
590 600 610 620 630
pF1KB5 LLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAK-EAAQK--AVNSATGVPTV
:::::::::::::::::::::::::::::::::.:: ::::: :: .::
NP_003 LLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS
600 610 620 630 640
>>NP_001129125 (OMIM: 603407) polyadenylate-binding prot (660 aa)
initn: 3391 init1: 2487 opt: 2646 Z-score: 1334.3 bits: 257.1 E(85289): 1.4e-67
Smith-Waterman score: 3200; 75.4% identity (87.0% similar) in 670 aa overlap (1-631:1-659)
10 20 30 40 50 60
pF1KB5 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
:: .: ::::::::::::: ::::::::::::::::.:::::::::::::::::::::::
NP_001 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
:::::::::::::::::::::.::::::::::::::::::.:::::::::::::::::::
NP_001 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
::::::::::::::::::::.::::::::::..:::::::::::::::::::::::::::
NP_001 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
:::::.::::::::::::::..::: ::.::..:: .:::::: : .::::::::::.:.
NP_001 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
::::.:::.::::::..:: :.:::::::::::.::::::::.::.::.::::::::.::
NP_001 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
::: ::::.:::::::::.:::::::.: :::::::::::::::::::::::::::::..
NP_001 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVP-NPVINPYQPAPPSGYFMAAIPQTQNR
::::::::::::::.::::::::::.:..::.: : ..: .::: .:::. :.::.:.:
NP_001 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAA-GGYFVPAVPQAQGR
370 380 390 400 410
420 430 440 450 460 470
pF1KB5 AAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRP-----ASSQVP
:: :.:.::.::.::: ::.::. ::.::.::: ..::: . . : :: .:
NP_001 PPYYTPNQLAQMRPNPRWQ-QGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLP
420 430 440 450 460 470
480 490 500
pF1KB5 RVMSTQRVAN------------------------------TSTQTMGPRPAAAAAAATPA
.::::.. :..:...:: ::.:::.:
NP_001 T--TTQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPR--AAVAAAAP-
480 490 500 510 520 530
510 520 530 540 550 560
pF1KB5 VRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGE
:.: ::::..::.: : :: . ::::::::::::::::::.::::::::::::
NP_001 -RAVAPYKYASSVRSP--HPAIQP-LQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGE
540 550 560 570 580
570 580 590 600 610 620
pF1KB5 RLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAK-EAA
:::::::.:: .:::::::::::::::::::::::::::::::::::::::::.:: :::
NP_001 RLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAA
590 600 610 620 630 640
630
pF1KB5 QK--AVNSATGVPTV
:: :: .::
NP_001 QKVGAVAAATS
650 660
>>NP_543022 (OMIM: 300407) polyadenylate-binding protein (382 aa)
initn: 1791 init1: 838 opt: 1606 Z-score: 822.7 bits: 161.7 E(85289): 4.4e-39
Smith-Waterman score: 1606; 64.3% identity (84.5% similar) in 373 aa overlap (2-371:7-379)
10 20 30 40 50
pF1KB5 MNPSAPS--YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLG
::.. . : :.:::::: ::::: :::.:: ::::. :.::: .:: ::
NP_543 MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 YAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNK
:.::::. ::::: ::.:::::.:.::: :.:::: : ::::::::::::::::::::.
NP_543 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 ALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRF
::. :::::::::::::::.::::::..:::.. ::.::: .:::. ::.:.:.::::
NP_543 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 KSRKEREAELGARAKE-FTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG
: .:: ::. .: . ::::..::.:.:.:::.::.:: ..::. ::::. : ::::::
NP_543 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQ
:::: .: :: ::::: ...:: ..:: .::::::::.:: .::.:.::... . .:
NP_543 FGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTE
:: .:.::::. :.::.:..::: ::.:. :::::: :..:::: ::::: ::::::: :
NP_543 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 MNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAA
::::::..:::.:.:.: .
NP_543 MNGRIVGSKPLHVTLGQARRRC
370 380
>>NP_005841 (OMIM: 154400,605593) splicing factor 3B sub (424 aa)
initn: 434 init1: 183 opt: 402 Z-score: 226.9 bits: 51.6 E(85289): 6.8e-06
Smith-Waterman score: 402; 39.9% identity (67.8% similar) in 183 aa overlap (11-189:13-192)
10 20 30 40 50
pF1KB5 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVN
:..::: : :.: .:.: : :::... .. .: .: . ::..:.
NP_005 MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 FQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVG-NIFIKNLDKSIDNKALYD
: . ::. :. ::. . :::.:. .. . .. :: :::: ::: ::.: :::
NP_005 FLSEEDADYAIKIMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYD
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 TFSAFGNILSC-KVVCDEN--GSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFK
:::::: ::. :.. : . .::::.:..: . .:.. ::: :::. : .: . :. .
NP_005 TFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 SRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFG
.:. ..: . : :
NP_005 FKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGM
180 190 200 210 220 230
>>NP_001310894 (OMIM: 603413) nucleolysin TIAR isoform 3 (252 aa)
initn: 344 init1: 147 opt: 295 Z-score: 176.4 bits: 41.5 E(85289): 0.0043
Smith-Waterman score: 295; 30.4% identity (58.0% similar) in 250 aa overlap (218-456:1-238)
190 200 210 220 230 240
pF1KB5 KEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQK
....:. : .:::::.::::: . ::..
NP_001 MDARVVKDMATGKSKGYGFVSFYNKLDAEN
10 20 30
250 260 270 280 290 300
pF1KB5 AVDEMNGKELNGKQIYVGRAQKKVER-QTELKRKFEQMK-QDRITRYQGVN--LYVKNLD
:. .:.:. :.:.:: .. : .: .. . . .:.. .: ... . : .: ..
NP_001 AIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIA
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB5 DGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKP
.:. :. .:. ::::: : .:. : ::..:: ::. : :..:.. .:: . .
NP_001 SGLTDQLMRQTFSPFGQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTIEGH-
100 110 120 130 140
370 380 390 400 410 420
pF1KB5 LYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVI-NPYQPAPPSGYFMAAIPQTQNRAA
: :: . .:....: : . . : :: : : .:: :. ..
NP_001 -VVKCYWGKE--SPDMTKNFQQVDYSQWGQWSQVYGNPQQ----YGQYMANGWQVPPYGV
150 160 170 180 190
430 440 450 460 470
pF1KB5 YYPP-SQIA---QLRPSPRWTAQ-GARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRV
: : .: . . :: : . ::.: : : .: :
NP_001 YGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ
200 210 220 230 240 250
480 490 500 510 520 530
pF1KB5 MSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPA
>>NP_001310893 (OMIM: 603413) nucleolysin TIAR isoform 3 (252 aa)
initn: 344 init1: 147 opt: 295 Z-score: 176.4 bits: 41.5 E(85289): 0.0043
Smith-Waterman score: 295; 30.4% identity (58.0% similar) in 250 aa overlap (218-456:1-238)
190 200 210 220 230 240
pF1KB5 KEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQK
....:. : .:::::.::::: . ::..
NP_001 MDARVVKDMATGKSKGYGFVSFYNKLDAEN
10 20 30
250 260 270 280 290 300
pF1KB5 AVDEMNGKELNGKQIYVGRAQKKVER-QTELKRKFEQMK-QDRITRYQGVN--LYVKNLD
:. .:.:. :.:.:: .. : .: .. . . .:.. .: ... . : .: ..
NP_001 AIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIA
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB5 DGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKP
.:. :. .:. ::::: : .:. : ::..:: ::. : :..:.. .:: . .
NP_001 SGLTDQLMRQTFSPFGQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTIEGH-
100 110 120 130 140
370 380 390 400 410 420
pF1KB5 LYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVI-NPYQPAPPSGYFMAAIPQTQNRAA
: :: . .:....: : . . : :: : : .:: :. ..
NP_001 -VVKCYWGKE--SPDMTKNFQQVDYSQWGQWSQVYGNPQQ----YGQYMANGWQVPPYGV
150 160 170 180 190
430 440 450 460 470
pF1KB5 YYPP-SQIA---QLRPSPRWTAQ-GARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRV
: : .: . . :: : . ::.: : : .: :
NP_001 YGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ
200 210 220 230 240 250
480 490 500 510 520 530
pF1KB5 MSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPA
636 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:01:39 2016 done: Thu Nov 3 18:01:40 2016
Total Scan time: 7.720 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]