Result of FASTA (omim) for
pF1KB5663
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5663, 295 aa
1>>>pF1KB5663 295 - 295 aa - 295 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8079+/-0.000332; mu= 13.8083+/- 0.021
mean_var=81.2801+/-16.174, 0's: 0 Z-trim(115.7): 59 B-trim: 966 in 1/53
Lambda= 0.142260
statistics sampled from 26254 (26315) to 26254 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.309), width: 16
Scan time: 5.320
The best scores are: opt bits E(85289)
NP_444284 (OMIM: 168461,193300,254500) G1/S-specif ( 295) 1948 409.1 5.1e-114
NP_001750 (OMIM: 123833,615938) G1/S-specific cycl ( 289) 1190 253.6 3.4e-67
NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 i ( 292) 993 213.1 5.1e-55
NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D ( 242) 765 166.3 5.4e-41
XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specif ( 276) 765 166.3 6e-41
NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D ( 211) 661 144.9 1.3e-34
XP_011513274 (OMIM: 123834) PREDICTED: G1/S-specif ( 195) 433 98.1 1.5e-20
NP_001129597 (OMIM: 123834) G1/S-specific cyclin-D ( 220) 408 93.0 5.6e-19
NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] ( 432) 327 76.5 9.9e-14
XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 320 75.1 2.6e-13
NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 320 75.1 2.6e-13
XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 320 75.1 2.6e-13
NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 320 75.1 2.6e-13
XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 320 75.1 2.6e-13
NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [H ( 464) 320 75.1 2.9e-13
NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo ( 465) 320 75.1 2.9e-13
NP_001309191 (OMIM: 123837) G1/S-specific cyclin-E ( 395) 306 72.2 1.8e-12
XP_011525742 (OMIM: 123837) PREDICTED: G1/S-specif ( 407) 306 72.2 1.9e-12
NP_001229 (OMIM: 123837) G1/S-specific cyclin-E1 i ( 410) 306 72.2 1.9e-12
XP_011515668 (OMIM: 603775) PREDICTED: G1/S-specif ( 288) 302 71.3 2.5e-12
NP_477097 (OMIM: 603775) G1/S-specific cyclin-E2 [ ( 404) 302 71.4 3.3e-12
XP_016869446 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 302 71.4 3.3e-12
XP_016869448 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 302 71.4 3.3e-12
XP_016869447 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 302 71.4 3.3e-12
NP_114172 (OMIM: 123836) G2/mitotic-specific cycli ( 433) 284 67.7 4.5e-11
NP_004692 (OMIM: 602755) G2/mitotic-specific cycli ( 398) 260 62.8 1.3e-09
NP_001309188 (OMIM: 123837) G1/S-specific cyclin-E ( 365) 250 60.7 4.9e-09
NP_001274363 (OMIM: 123834) G1/S-specific cyclin-D ( 96) 219 54.0 1.3e-07
NP_001129598 (OMIM: 123834) G1/S-specific cyclin-D ( 96) 219 54.0 1.3e-07
NP_066970 (OMIM: 607752,615872) cyclin-O [Homo sap ( 350) 222 54.9 2.6e-07
NP_004051 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 217 53.9 4.5e-07
NP_954854 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 217 53.9 4.5e-07
NP_001752 (OMIM: 600227) cyclin-F isoform 1 [Homo ( 786) 206 51.9 4.9e-06
XP_016879311 (OMIM: 600227) PREDICTED: cyclin-F is ( 867) 206 51.9 5.3e-06
XP_016885407 (OMIM: 300456) PREDICTED: G2/mitotic- (1395) 201 51.0 1.6e-05
NP_149020 (OMIM: 300456) G2/mitotic-specific cycli (1395) 201 51.0 1.6e-05
XP_016885406 (OMIM: 300456) PREDICTED: G2/mitotic- (1396) 201 51.0 1.6e-05
XP_016885405 (OMIM: 300456) PREDICTED: G2/mitotic- (1403) 198 50.4 2.5e-05
XP_016885404 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 198 50.4 2.5e-05
XP_016885403 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 198 50.4 2.5e-05
XP_016885402 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 198 50.4 2.5e-05
NP_001310467 (OMIM: 600227) cyclin-F isoform 2 [Ho ( 478) 190 48.4 3.1e-05
NP_001230 (OMIM: 601953) cyclin-H isoform 1 [Homo ( 323) 164 43.0 0.00092
XP_011542008 (OMIM: 601953) PREDICTED: cyclin-H is ( 325) 164 43.0 0.00092
XP_005248684 (OMIM: 601953) PREDICTED: cyclin-H is ( 329) 164 43.0 0.00093
NP_001186118 (OMIM: 601953) cyclin-H isoform 2 [Ho ( 270) 152 40.5 0.0044
XP_016865503 (OMIM: 601953) PREDICTED: cyclin-H is ( 272) 152 40.5 0.0044
XP_005248686 (OMIM: 601953) PREDICTED: cyclin-H is ( 276) 152 40.5 0.0045
NP_391990 (OMIM: 300456) G2/mitotic-specific cycli ( 291) 151 40.3 0.0054
XP_011530701 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 149 39.9 0.0082
>>NP_444284 (OMIM: 168461,193300,254500) G1/S-specific c (295 aa)
initn: 1948 init1: 1948 opt: 1948 Z-score: 2167.9 bits: 409.1 E(85289): 5.1e-114
Smith-Waterman score: 1948; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295)
10 20 30 40 50 60
pF1KB5 MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 AEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 HAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 HAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCD
190 200 210 220 230 240
250 260 270 280 290
pF1KB5 PDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 PDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI
250 260 270 280 290
>>NP_001750 (OMIM: 123833,615938) G1/S-specific cyclin-D (289 aa)
initn: 1176 init1: 1059 opt: 1190 Z-score: 1327.3 bits: 253.6 E(85289): 3.4e-67
Smith-Waterman score: 1190; 61.8% identity (81.9% similar) in 293 aa overlap (4-295:2-289)
10 20 30 40 50
pF1KB5 MEHQLLCCEVETIRRAYPDANLL-NDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKI
.::: ::. .::: : ::: .::::. .: :: :. ::::::::.. : ::..
NP_001 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRM
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 VATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPL
::::::::::::::::::::::::::::::. :. ::.::::::.:::.:::.::: ::
NP_001 VATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 TAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIR
:::::::::::::.:.:::. ::....::::::::.::::::::.: :.:. .:. ..::
NP_001 TAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 KHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKC
::::::.:::::: :: ::::.:.::: ::. ::. . :. ::..:... .
NP_001 KHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 DPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI
: :::.::::::::.: .::.: .:.. .. . :.:.: : :::::::.:.
NP_001 DVDCLKACQEQIEAVLLNSLQQYRQDQ-----RDGSKSEDELDQASTPTDVRDIDL
240 250 260 270 280
>>NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 isofo (292 aa)
initn: 989 init1: 809 opt: 993 Z-score: 1108.7 bits: 213.1 E(85289): 5.1e-55
Smith-Waterman score: 993; 51.9% identity (75.9% similar) in 295 aa overlap (4-295:2-292)
10 20 30 40 50
pF1KB5 MEHQLLCCE-VETIRRAYPDANLLND-RVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRK
.::::: .. :: :: ::.: :::...:. :: .: .:::.:::.:. : :::
NP_001 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRK
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 IVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIP
..: :::::::::.:::::::::::::::.:: :..:..::::::.::..:::..:: :
NP_001 MLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 LTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQII
:: ::::::::... :..: . :.:...::::.:::. :::. .: .. .. . ..
NP_001 LTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 RKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIK
.::::::.:::::: : ::::.:.::. ::::::. : .: .::..:. .
NP_001 KKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACS----MSGDELTELLAGITG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 CDPDCLRACQEQIEALLESSLRQAQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI
. :::::::::::: :. :::.:.: . .: . . . . ::::: . .
NP_001 TEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
240 250 260 270 280 290
>>NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D3 is (242 aa)
initn: 785 init1: 635 opt: 765 Z-score: 857.0 bits: 166.3 E(85289): 5.4e-41
Smith-Waterman score: 765; 51.3% identity (75.7% similar) in 230 aa overlap (67-295:17-242)
40 50 60 70 80 90
pF1KB5 TCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKK
:::::.:::::::::::::::.:: :..:
NP_001 MKSAGGSGRSLLPSPRVCEEQRCEEEVFPLAMNYLDRYLSCVPTRK
10 20 30 40
100 110 120 130 140 150
pF1KB5 SRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMT
..::::::.::..:::..:: ::: ::::::::... :..: . :.:...::::.:::.
NP_001 AQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVI
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB5 PHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLN
:::. .: .. .. . ...::::::.:::::: : ::::.:.::. ::::::.
NP_001 AHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB5 LRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQ-NMDPKAAEEEE
: .: .::..:. . . :::::::::::: :. :::.:.: . .: .
NP_001 ACS----MSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRG
170 180 190 200 210 220
280 290
pF1KB5 EEEEEVDLACTPTDVRDVDI
. . . ::::: . .
NP_001 SSSQGPSQTSTPTDVTAIHL
230 240
>>XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specific c (276 aa)
initn: 741 init1: 711 opt: 765 Z-score: 856.2 bits: 166.3 E(85289): 6e-41
Smith-Waterman score: 765; 57.4% identity (83.2% similar) in 190 aa overlap (4-191:2-191)
10 20 30 40 50
pF1KB5 MEHQLLCCE-VETIRRAYPDANLLND-RVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRK
.::::: .. :: :: ::.: :::...:. :: .: .:::.:::.:. : :::
XP_011 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRK
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 IVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIP
..: :::::::::.:::::::::::::::.:: :..:..::::::.::..:::..:: :
XP_011 MLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 LTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQII
:: ::::::::... :..: . :.:...::::.:::. :::. .: .. .. . ..
XP_011 LTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 RKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIK
.::::::.:::::
XP_011 KKHAQTFLALCATGLPAGLSGADRSCTQGEPQGSLSDQLQPSAQSPPGLQQPRAQPDQHS
180 190 200 210 220 230
>>NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D3 is (211 aa)
initn: 681 init1: 531 opt: 661 Z-score: 742.6 bits: 144.9 E(85289): 1.3e-34
Smith-Waterman score: 661; 48.4% identity (74.0% similar) in 215 aa overlap (82-295:1-211)
60 70 80 90 100 110
pF1KB5 VLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVAS
::::::.:: :..:..::::::.::..::
NP_001 MNYLDRYLSCVPTRKAQLQLLGAVCMLLAS
10 20 30
120 130 140 150 160 170
pF1KB5 KMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEA
:..:: ::: ::::::::... :..: . :.:...::::.:::. :::. .: ..
NP_001 KLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLP
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB5 EENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTR
.. . ...::::::.:::::: : ::::.:.::. ::::::. : .: .::.
NP_001 RDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACS----MSGDELTE
100 110 120 130 140
240 250 260 270 280 290
pF1KB5 FLSRVIKCDPDCLRACQEQIEALLESSLRQAQQ-NMDPKAAEEEEEEEEEVDLACTPTDV
.:. . . :::::::::::: :. :::.:.: . .: . . . . :::::
NP_001 LLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDV
150 160 170 180 190 200
pF1KB5 RDVDI
. .
NP_001 TAIHL
210
>>XP_011513274 (OMIM: 123834) PREDICTED: G1/S-specific c (195 aa)
initn: 433 init1: 433 opt: 433 Z-score: 490.2 bits: 98.1 E(85289): 1.5e-20
Smith-Waterman score: 433; 54.5% identity (84.5% similar) in 110 aa overlap (82-191:1-110)
60 70 80 90 100 110
pF1KB5 VLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVAS
::::::.:: :..:..::::::.::..::
XP_011 MNYLDRYLSCVPTRKAQLQLLGAVCMLLAS
10 20 30
120 130 140 150 160 170
pF1KB5 KMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEA
:..:: ::: ::::::::... :..: . :.:...::::.:::. :::. .: ..
XP_011 KLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLP
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB5 EENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTR
.. . ...::::::.:::::
XP_011 RDRQALVKKHAQTFLALCATGLPAGLSGADRSCTQGEPQGSLSDQLQPSAQSPPGLQQPR
100 110 120 130 140 150
>>NP_001129597 (OMIM: 123834) G1/S-specific cyclin-D3 is (220 aa)
initn: 488 init1: 278 opt: 408 Z-score: 461.7 bits: 93.0 E(85289): 5.6e-19
Smith-Waterman score: 480; 34.9% identity (53.6% similar) in 295 aa overlap (4-295:2-220)
10 20 30 40 50
pF1KB5 MEHQLLCCE-VETIRRAYPDANLLND-RVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRK
.::::: .. :: :: ::.: :::...:. :: .: .:::.:::.:. : :::
NP_001 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRK
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 IVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIP
..: ::::
NP_001 MLAYWMLE----------------------------------------------------
60
120 130 140 150 160 170
pF1KB5 LTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQII
. :.:...::::.:::. :::. .: .. .. . ..
NP_001 --------------------DWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALV
70 80 90 100
180 190 200 210 220 230
pF1KB5 RKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIK
.::::::.:::::: : ::::.:.::. ::::::. : .: .::..:. .
NP_001 KKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACS----MSGDELTELLAGITG
110 120 130 140 150 160
240 250 260 270 280 290
pF1KB5 CDPDCLRACQEQIEALLESSLRQAQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI
. :::::::::::: :. :::.:.: . .: . . . . ::::: . .
NP_001 TEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
170 180 190 200 210 220
>>NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] (432 aa)
initn: 277 init1: 277 opt: 327 Z-score: 367.5 bits: 76.5 E(85289): 9.9e-14
Smith-Waterman score: 327; 30.2% identity (61.9% similar) in 252 aa overlap (18-265:176-415)
10 20 30 40
pF1KB5 MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKC
:: . :: : : : :.:.:.:
NP_001 YPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHEDIHTYLREM---EVKCKPKVGYMKK
150 160 170 180 190 200
50 60 70 80 90 100
pF1KB5 VQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCM
: .. ::: :.. :..:: :: : ..:.. ::.::.::::: : ...:::.:.. :
NP_001 -QPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAM
210 220 230 240 250 260
110 120 130 140 150 160
pF1KB5 FVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFI-EHFLS
..:::..: : . .. ::.. ...:.:: :... : ..::: : ..:. ..::
NP_001 LLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLH
270 280 290 300 310 320
170 180 190 200 210 220
pF1KB5 KMPEAEENKQIIRKHAQTFVALCATDVK-FISNPPSMVAAGSVVAAVQGLNLRS-PNNFL
..: . ... :. . : :. ... ::..:... :. .. .: :....
NP_001 QQPANCK----VESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLI
330 340 350 360 370
230 240 250 260 270 280
pF1KB5 SYYRLTRFLSRVIK-CDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDL
: : . . .: : : :. . ..:.:. .:
NP_001 ---RKTGYTLESLKPCLMD-LHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL
380 390 400 410 420 430
290
pF1KB5 ACTPTDVRDVDI
>>XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa)
initn: 266 init1: 266 opt: 320 Z-score: 359.9 bits: 75.1 E(85289): 2.6e-13
Smith-Waterman score: 320; 29.2% identity (66.2% similar) in 216 aa overlap (25-239:169-378)
10 20 30 40 50
pF1KB5 MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLP
... . . .:: :.. :.: : ..
XP_011 SPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKK-QPDITE
140 150 160 170 180 190
60 70 80 90 100 110
pF1KB5 SMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMK
.:: :.. :..:: :: : . :.. ::.:.:::::: : ...:::.:.. :..:::..
XP_011 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYE
200 210 220 230 240 250
120 130 140 150 160 170
pF1KB5 ETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEEN
: : .... ::.. ..::.:: ::.. : ..:.. : ..:. ..: .. ..
XP_011 EIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRT
260 270 280 290 300 310
180 190 200 210 220 230
pF1KB5 KQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRS-PNNFLSYYRLTRFL
... . :. ..: .: :.. ::..::.. : .: . :... .. . :
XP_011 ENLAKYVAE--LSLLEAD-PFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYS--L
320 330 340 350 360 370
240 250 260 270 280 290
pF1KB5 SRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDV
:... :
XP_011 SEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
380 390 400 410 420
295 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:54:15 2016 done: Thu Nov 3 17:54:16 2016
Total Scan time: 5.320 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]