Result of FASTA (omim) for
pF1KB5641
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5641, 759 aa
1>>>pF1KB5641 759 - 759 aa - 759 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5810+/-0.000317; mu= 9.5387+/- 0.020
mean_var=134.0388+/-27.309, 0's: 0 Z-trim(119.3): 63 B-trim: 0 in 0/59
Lambda= 0.110779
statistics sampled from 33178 (33241) to 33178 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.39), width: 16
Scan time: 13.730
The best scores are: opt bits E(85289)
XP_016863634 (OMIM: 104300,602710) PREDICTED: amyl ( 759) 5107 828.0 0
NP_004298 (OMIM: 104300,602710) amyloid beta A4 pr ( 759) 5107 828.0 0
XP_006714068 (OMIM: 104300,602710) PREDICTED: amyl ( 761) 5093 825.7 0
XP_016863631 (OMIM: 104300,602710) PREDICTED: amyl ( 761) 5093 825.7 0
XP_011511988 (OMIM: 104300,602710) PREDICTED: amyl ( 761) 5093 825.7 0
XP_006714071 (OMIM: 104300,602710) PREDICTED: amyl ( 761) 5093 825.7 0
XP_006714070 (OMIM: 104300,602710) PREDICTED: amyl ( 761) 5093 825.7 0
XP_006714072 (OMIM: 104300,602710) PREDICTED: amyl ( 761) 5093 825.7 0
NP_001159522 (OMIM: 104300,602710) amyloid beta A4 ( 758) 5090 825.3 0
XP_016863632 (OMIM: 104300,602710) PREDICTED: amyl ( 760) 5076 823.0 0
XP_016863633 (OMIM: 104300,602710) PREDICTED: amyl ( 760) 5076 823.0 0
XP_006714073 (OMIM: 104300,602710) PREDICTED: amyl ( 760) 5076 823.0 0
XP_016863635 (OMIM: 104300,602710) PREDICTED: amyl ( 744) 4988 809.0 0
XP_016863636 (OMIM: 104300,602710) PREDICTED: amyl ( 744) 4988 809.0 0
XP_016863637 (OMIM: 104300,602710) PREDICTED: amyl ( 744) 4988 809.0 0
XP_016863638 (OMIM: 104300,602710) PREDICTED: amyl ( 743) 4971 806.2 0
XP_011511990 (OMIM: 104300,602710) PREDICTED: amyl ( 512) 3439 561.3 3.6e-159
XP_016863647 (OMIM: 104300,602710) PREDICTED: amyl ( 721) 2663 437.4 1e-121
NP_001317585 (OMIM: 104300,602710) amyloid beta A4 ( 737) 2663 437.4 1e-121
NP_001317587 (OMIM: 104300,602710) amyloid beta A4 ( 737) 2663 437.4 1e-121
XP_016863643 (OMIM: 104300,602710) PREDICTED: amyl ( 738) 2663 437.4 1e-121
XP_011511989 (OMIM: 104300,602710) PREDICTED: amyl ( 738) 2663 437.4 1e-121
XP_016863642 (OMIM: 104300,602710) PREDICTED: amyl ( 738) 2663 437.4 1e-121
XP_006714074 (OMIM: 104300,602710) PREDICTED: amyl ( 740) 2316 381.9 5.2e-105
XP_016863640 (OMIM: 104300,602710) PREDICTED: amyl ( 740) 2316 381.9 5.2e-105
XP_016863639 (OMIM: 104300,602710) PREDICTED: amyl ( 740) 2316 381.9 5.2e-105
XP_016863648 (OMIM: 104300,602710) PREDICTED: amyl ( 488) 2299 379.1 2.4e-104
NP_775098 (OMIM: 104300,602710) amyloid beta A4 pr ( 736) 2299 379.2 3.4e-104
XP_006714075 (OMIM: 104300,602710) PREDICTED: amyl ( 739) 2299 379.2 3.4e-104
XP_016863641 (OMIM: 104300,602710) PREDICTED: amyl ( 739) 2299 379.2 3.4e-104
XP_016863646 (OMIM: 104300,602710) PREDICTED: amyl ( 723) 2211 365.1 5.7e-100
XP_016863645 (OMIM: 104300,602710) PREDICTED: amyl ( 723) 2211 365.1 5.7e-100
XP_006718277 (OMIM: 602709) PREDICTED: amyloid bet ( 713) 1749 291.3 9.6e-78
XP_016873129 (OMIM: 602709) PREDICTED: amyloid bet ( 713) 1749 291.3 9.6e-78
XP_006718275 (OMIM: 602709) PREDICTED: amyloid bet ( 715) 1735 289.0 4.5e-77
XP_016873128 (OMIM: 602709) PREDICTED: amyloid bet ( 715) 1735 289.0 4.5e-77
NP_663722 (OMIM: 602709) amyloid beta A4 precursor ( 708) 1610 269.1 4.6e-71
XP_016873130 (OMIM: 602709) PREDICTED: amyloid bet ( 708) 1610 269.1 4.6e-71
NP_001244252 (OMIM: 602709) amyloid beta A4 precur ( 488) 1599 267.2 1.1e-70
NP_001155 (OMIM: 602709) amyloid beta A4 precursor ( 710) 1596 266.8 2.2e-70
XP_006718278 (OMIM: 602709) PREDICTED: amyloid bet ( 802) 1596 266.9 2.4e-70
XP_016873131 (OMIM: 602709) PREDICTED: amyloid bet ( 449) 1589 265.6 3.2e-70
NP_001244254 (OMIM: 602709) amyloid beta A4 precur ( 475) 1585 265.0 5.3e-70
NP_001244248 (OMIM: 602709) amyloid beta A4 precur ( 490) 1585 265.0 5.4e-70
NP_001244249 (OMIM: 602709) amyloid beta A4 precur ( 451) 1575 263.4 1.5e-69
NP_001244255 (OMIM: 602709) amyloid beta A4 precur ( 451) 1575 263.4 1.5e-69
NP_001244250 (OMIM: 602709) amyloid beta A4 precur ( 451) 1575 263.4 1.5e-69
XP_011518342 (OMIM: 602709) PREDICTED: amyloid bet ( 451) 1575 263.4 1.5e-69
NP_001159526 (OMIM: 104300,602710) amyloid beta A4 ( 210) 1402 235.5 1.7e-61
NP_001159523 (OMIM: 104300,602710) amyloid beta A4 ( 210) 1402 235.5 1.7e-61
>>XP_016863634 (OMIM: 104300,602710) PREDICTED: amyloid (759 aa)
initn: 5107 init1: 5107 opt: 5107 Z-score: 4416.8 bits: 828.0 E(85289): 0
Smith-Waterman score: 5107; 99.9% identity (100.0% similar) in 759 aa overlap (1-759:1-759)
10 20 30 40 50 60
pF1KB5 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_016 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRDFAYVARDKDTRILKCHVFRCDTPAKAIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRDFAYVARDKDTRILKCHVFRCDTPAKAIAT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 SLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGMLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 VDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFLSF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 MGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQKV
670 680 690 700 710 720
730 740 750
pF1KB5 RPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
:::::::::::::::::::::::::::::::::::::::
XP_016 RPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
730 740 750
>>NP_004298 (OMIM: 104300,602710) amyloid beta A4 precur (759 aa)
initn: 5107 init1: 5107 opt: 5107 Z-score: 4416.8 bits: 828.0 E(85289): 0
Smith-Waterman score: 5107; 99.9% identity (100.0% similar) in 759 aa overlap (1-759:1-759)
10 20 30 40 50 60
pF1KB5 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_004 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRDFAYVARDKDTRILKCHVFRCDTPAKAIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRDFAYVARDKDTRILKCHVFRCDTPAKAIAT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 SLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGMLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 VDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFLSF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 MGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQKV
670 680 690 700 710 720
730 740 750
pF1KB5 RPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
:::::::::::::::::::::::::::::::::::::::
NP_004 RPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
730 740 750
>>XP_006714068 (OMIM: 104300,602710) PREDICTED: amyloid (761 aa)
initn: 3495 init1: 3444 opt: 5093 Z-score: 4404.7 bits: 825.7 E(85289): 0
Smith-Waterman score: 5093; 99.6% identity (99.7% similar) in 761 aa overlap (1-759:1-761)
10 20 30 40 50 60
pF1KB5 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_006 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGR--DFAYVARDKDTRILKCHVFRCDTPAKAI
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_006 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRERDFAYVARDKDTRILKCHVFRCDTPAKAI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB5 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
670 680 690 700 710 720
720 730 740 750
pF1KB5 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
:::::::::::::::::::::::::::::::::::::::::
XP_006 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
730 740 750 760
>>XP_016863631 (OMIM: 104300,602710) PREDICTED: amyloid (761 aa)
initn: 3495 init1: 3444 opt: 5093 Z-score: 4404.7 bits: 825.7 E(85289): 0
Smith-Waterman score: 5093; 99.6% identity (99.7% similar) in 761 aa overlap (1-759:1-761)
10 20 30 40 50 60
pF1KB5 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_016 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGR--DFAYVARDKDTRILKCHVFRCDTPAKAI
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_016 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRERDFAYVARDKDTRILKCHVFRCDTPAKAI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB5 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
670 680 690 700 710 720
720 730 740 750
pF1KB5 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
:::::::::::::::::::::::::::::::::::::::::
XP_016 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
730 740 750 760
>>XP_011511988 (OMIM: 104300,602710) PREDICTED: amyloid (761 aa)
initn: 3495 init1: 3444 opt: 5093 Z-score: 4404.7 bits: 825.7 E(85289): 0
Smith-Waterman score: 5093; 99.6% identity (99.7% similar) in 761 aa overlap (1-759:1-761)
10 20 30 40 50 60
pF1KB5 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_011 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGR--DFAYVARDKDTRILKCHVFRCDTPAKAI
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_011 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRERDFAYVARDKDTRILKCHVFRCDTPAKAI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB5 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
670 680 690 700 710 720
720 730 740 750
pF1KB5 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
:::::::::::::::::::::::::::::::::::::::::
XP_011 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
730 740 750 760
>>XP_006714071 (OMIM: 104300,602710) PREDICTED: amyloid (761 aa)
initn: 3495 init1: 3444 opt: 5093 Z-score: 4404.7 bits: 825.7 E(85289): 0
Smith-Waterman score: 5093; 99.6% identity (99.7% similar) in 761 aa overlap (1-759:1-761)
10 20 30 40 50 60
pF1KB5 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_006 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGR--DFAYVARDKDTRILKCHVFRCDTPAKAI
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_006 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRERDFAYVARDKDTRILKCHVFRCDTPAKAI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB5 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
670 680 690 700 710 720
720 730 740 750
pF1KB5 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
:::::::::::::::::::::::::::::::::::::::::
XP_006 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
730 740 750 760
>>XP_006714070 (OMIM: 104300,602710) PREDICTED: amyloid (761 aa)
initn: 3495 init1: 3444 opt: 5093 Z-score: 4404.7 bits: 825.7 E(85289): 0
Smith-Waterman score: 5093; 99.6% identity (99.7% similar) in 761 aa overlap (1-759:1-761)
10 20 30 40 50 60
pF1KB5 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_006 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGR--DFAYVARDKDTRILKCHVFRCDTPAKAI
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_006 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRERDFAYVARDKDTRILKCHVFRCDTPAKAI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB5 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
670 680 690 700 710 720
720 730 740 750
pF1KB5 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
:::::::::::::::::::::::::::::::::::::::::
XP_006 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
730 740 750 760
>>XP_006714072 (OMIM: 104300,602710) PREDICTED: amyloid (761 aa)
initn: 3495 init1: 3444 opt: 5093 Z-score: 4404.7 bits: 825.7 E(85289): 0
Smith-Waterman score: 5093; 99.6% identity (99.7% similar) in 761 aa overlap (1-759:1-761)
10 20 30 40 50 60
pF1KB5 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_006 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGR--DFAYVARDKDTRILKCHVFRCDTPAKAI
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_006 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRERDFAYVARDKDTRILKCHVFRCDTPAKAI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB5 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
670 680 690 700 710 720
720 730 740 750
pF1KB5 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
:::::::::::::::::::::::::::::::::::::::::
XP_006 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
730 740 750 760
>>NP_001159522 (OMIM: 104300,602710) amyloid beta A4 pre (758 aa)
initn: 3297 init1: 3297 opt: 5090 Z-score: 4402.1 bits: 825.3 E(85289): 0
Smith-Waterman score: 5090; 99.7% identity (99.9% similar) in 759 aa overlap (1-759:1-758)
10 20 30 40 50 60
pF1KB5 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_001 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDET-DIWSDHSFQTDPDLPPGWKRV
250 260 270 280 290
310 320 330 340 350 360
pF1KB5 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB5 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRDFAYVARDKDTRILKCHVFRCDTPAKAIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRDFAYVARDKDTRILKCHVFRCDTPAKAIAT
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB5 SLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGMLP
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB5 VDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFLSF
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB5 MGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQKV
660 670 680 690 700 710
730 740 750
pF1KB5 RPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
:::::::::::::::::::::::::::::::::::::::
NP_001 RPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
720 730 740 750
>>XP_016863632 (OMIM: 104300,602710) PREDICTED: amyloid (760 aa)
initn: 3471 init1: 1810 opt: 5076 Z-score: 4390.0 bits: 823.0 E(85289): 0
Smith-Waterman score: 5076; 99.5% identity (99.6% similar) in 761 aa overlap (1-759:1-760)
10 20 30 40 50 60
pF1KB5 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_016 NLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETADIWSDHSFQTDPDLPPGWKRV
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_016 AKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDET-DIWSDHSFQTDPDLPPGWKRV
250 260 270 280 290
310 320 330 340 350 360
pF1KB5 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNG
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCF
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDML
420 430 440 450 460 470
490 500 510 520 530
pF1KB5 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGR--DFAYVARDKDTRILKCHVFRCDTPAKAI
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_016 SLVDPMDRSVLHSQPIVSIRVWGVGRDNGRERDFAYVARDKDTRILKCHVFRCDTPAKAI
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB5 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGM
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB5 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFL
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB5 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQ
660 670 680 690 700 710
720 730 740 750
pF1KB5 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
:::::::::::::::::::::::::::::::::::::::::
XP_016 KVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
720 730 740 750 760
759 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:45:51 2016 done: Thu Nov 3 08:45:53 2016
Total Scan time: 13.730 Total Display time: 0.270
Function used was FASTA [36.3.4 Apr, 2011]