Result of FASTA (omim) for
pF1KB5493
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5493, 908 aa
1>>>pF1KB5493 908 - 908 aa - 908 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5654+/-0.000415; mu= 16.0202+/- 0.026
mean_var=106.1575+/-20.527, 0's: 0 Z-trim(113.6): 12 B-trim: 435 in 1/52
Lambda= 0.124480
statistics sampled from 23055 (23062) to 23055 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.27), width: 16
Scan time: 12.180
The best scores are: opt bits E(85289)
NP_002799 (OMIM: 606223) 26S proteasome non-ATPase ( 908) 5896 1070.3 0
NP_001265637 (OMIM: 606223) 26S proteasome non-ATP ( 778) 5047 917.8 0
NP_001265638 (OMIM: 606223) 26S proteasome non-ATP ( 749) 4825 877.9 0
>>NP_002799 (OMIM: 606223) 26S proteasome non-ATPase reg (908 aa)
initn: 5896 init1: 5896 opt: 5896 Z-score: 5723.7 bits: 1070.3 E(85289): 0
Smith-Waterman score: 5896; 99.9% identity (99.9% similar) in 908 aa overlap (1-908:1-908)
10 20 30 40 50 60
pF1KB5 MEEGGRDKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQELSEEDKQLQDELEMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MEEGGRDKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQELSEEDKQLQDELEMLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 FAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVRHLAGEVAKEWQELDDAEKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVRHLAGEVAKEWQELDDAEKVQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 REPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 REPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PEPENSALLCCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGR
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 HGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 DVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 SIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 TIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 AGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 AMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 VSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 YHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 PVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVIL
850 860 870 880 890 900
pF1KB5 RKNPNYDL
::::::::
NP_002 RKNPNYDL
>>NP_001265637 (OMIM: 606223) 26S proteasome non-ATPase (778 aa)
initn: 5047 init1: 5047 opt: 5047 Z-score: 4900.7 bits: 917.8 E(85289): 0
Smith-Waterman score: 5047; 99.9% identity (99.9% similar) in 778 aa overlap (131-908:1-778)
110 120 130 140 150 160
pF1KB5 PHYGKLKEIYENMAPGENKRFAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVR
::::::::::::::::::::::::::::::
NP_001 MTMSGERECLKYRLVGSQEELASWGHEYVR
10 20 30
170 180 190 200 210 220
pF1KB5 HLAGEVAKEWQELDDAEKVQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLAGEVAKEWQELDDAEKVQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKD
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB5 IDENAYAKVCLYLTSCVNYVPEPENSALLCCALGVFRKFSRFPEALRLALMLNDMELVED
::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
NP_001 IDENAYAKVCLYLTSCVNYVPEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVED
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB5 IFTSCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFTSCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIM
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB5 EPKVPDDIYKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPKVPDDIYKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLY
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB5 KNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECD
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB5 PALALLSDYVLHNSNTMRLGSIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PALALLSDYVLHNSNTMRLGSIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTAL
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB5 ACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAAL
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB5 EVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKK
460 470 480 490 500 510
650 660 670 680 690 700
pF1KB5 EAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVS
520 530 540 550 560 570
710 720 730 740 750 760
pF1KB5 NPRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLF
580 590 600 610 620 630
770 780 790 800 810 820
pF1KB5 MVRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYG
640 650 660 670 680 690
830 840 850 860 870 880
pF1KB5 LVAAMQPRMLVTFDEELRPLPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVAAMQPRMLVTFDEELRPLPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERA
700 710 720 730 740 750
890 900
pF1KB5 ELATEEFLPVTPILEGFVILRKNPNYDL
::::::::::::::::::::::::::::
NP_001 ELATEEFLPVTPILEGFVILRKNPNYDL
760 770
>>NP_001265638 (OMIM: 606223) 26S proteasome non-ATPase (749 aa)
initn: 4825 init1: 4825 opt: 4825 Z-score: 4685.5 bits: 877.9 E(85289): 0
Smith-Waterman score: 4825; 99.6% identity (99.9% similar) in 747 aa overlap (162-908:3-749)
140 150 160 170 180 190
pF1KB5 TMSGERECLKYRLVGSQEELASWGHEYVRHLAGEVAKEWQELDDAEKVQREPLLTLVKEI
..::::::::::::::::::::::::::::
NP_001 MSMSGEVAKEWQELDDAEKVQREPLLTLVKEI
10 20 30
200 210 220 230 240 250
pF1KB5 VPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEPENSALLCC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 VPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEPENSALLRC
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB5 ALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSEDV
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB5 EEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGGSGSQVDSARMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGGSGSQVDSARMN
160 170 180 190 200 210
380 390 400 410 420 430
pF1KB5 LASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDK
220 230 240 250 260 270
440 450 460 470 480 490
pF1KB5 YLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLGSIFGLGLAYAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLGSIFGLGLAYAG
280 290 300 310 320 330
500 510 520 530 540 550
pF1KB5 SNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELK
340 350 360 370 380 390
560 570 580 590 600 610
pF1KB5 DTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQ
400 410 420 430 440 450
620 630 640 650 660 670
pF1KB5 LLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALIAMGEEIGAEMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALIAMGEEIGAEMA
460 470 480 490 500 510
680 690 700 710 720 730
pF1KB5 LRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSYNSIFAMGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSYNSIFAMGM
520 530 540 550 560 570
740 750 760 770 780 790
pF1KB5 VGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCPYHSDRQLMSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCPYHSDRQLMSQV
580 590 600 610 620 630
800 810 820 830 840 850
pF1KB5 AVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQAVD
640 650 660 670 680 690
860 870 880 890 900
pF1KB5 VVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYDL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYDL
700 710 720 730 740
908 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:28:04 2016 done: Thu Nov 3 17:28:06 2016
Total Scan time: 12.180 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]