FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5474, 246 aa
1>>>pF1KB5474 246 - 246 aa - 246 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4240+/-0.000963; mu= 9.2922+/- 0.058
mean_var=84.1534+/-16.838, 0's: 0 Z-trim(105.3): 23 B-trim: 106 in 1/52
Lambda= 0.139810
statistics sampled from 8345 (8353) to 8345 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.257), width: 16
Scan time: 2.280
The best scores are: opt bits E(32554)
CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 ( 246) 1568 325.9 1.5e-89
CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 ( 245) 1368 285.6 2.1e-77
CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 ( 245) 1287 269.3 1.7e-72
CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 ( 247) 1164 244.5 5.1e-65
CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 ( 246) 1150 241.6 3.6e-64
CCDS288.1 SFN gene_id:2810|Hs108|chr1 ( 248) 1060 223.5 1.1e-58
CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 ( 255) 1024 216.2 1.7e-56
>>CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 (246 aa)
initn: 1568 init1: 1568 opt: 1568 Z-score: 1721.2 bits: 325.9 E(32554): 1.5e-89
Smith-Waterman score: 1568; 100.0% identity (100.0% similar) in 246 aa overlap (1-246:1-246)
10 20 30 40 50 60
pF1KB5 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD
190 200 210 220 230 240
pF1KB5 AGEGEN
::::::
CCDS13 AGEGEN
>>CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 (245 aa)
initn: 1367 init1: 1367 opt: 1368 Z-score: 1503.2 bits: 285.6 E(32554): 2.1e-77
Smith-Waterman score: 1368; 87.3% identity (96.3% similar) in 245 aa overlap (3-246:1-245)
10 20 30 40 50 60
pF1KB5 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
:::.:::::::::::::::::::: ::.::::: ::::::::::::::::::::::::
CCDS62 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSS
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY
:::.:::::::: ::::::..:::::::.::.::::::: ::.:.:::::.: ::::::
CCDS62 WRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
:::::::.:::.:::.::.:. :..::::::::::::::::::::::::::::::::::
CCDS62 LKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD
::::::::::::::::::::::::::::.:::::::::::::::::::::::..::::..
CCDS62 YEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAE
180 190 200 210 220 230
pF1KB5 AGEG-EN
:::: ::
CCDS62 AGEGGEN
240
>>CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 (245 aa)
initn: 1286 init1: 1286 opt: 1287 Z-score: 1414.9 bits: 269.3 E(32554): 1.7e-72
Smith-Waterman score: 1287; 81.6% identity (94.3% similar) in 245 aa overlap (3-246:1-245)
10 20 30 40 50 60
pF1KB5 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
:.:.::.::::::::::::::::. :::::::: :::::::::::::::::::.:::.
CCDS16 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSA
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY
:::::::::::. ..:: :. :.::::.:.::..::. :::::::::: :::.:::::::
CCDS16 WRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
:::::::::::.::: ::... :..::: ::::::.::::::::::::::::::::::::
CCDS16 LKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD
:::::.:: ::.::::::::::::::::::.:::::::::::::::::::::.. :.: :
CCDS16 YEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECD
180 190 200 210 220 230
pF1KB5 AGEG-EN
:.:: ::
CCDS16 AAEGAEN
240
>>CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 (247 aa)
initn: 1021 init1: 669 opt: 1164 Z-score: 1280.8 bits: 244.5 E(32554): 5.1e-65
Smith-Waterman score: 1164; 75.4% identity (89.5% similar) in 248 aa overlap (3-246:2-247)
10 20 30 40 50 60
pF1KB5 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
.:. .:::::.:::::::::::::::: ::: .. :::::::::::::::::::::::
CCDS55 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSS
10 20 30 40 50
70 80 90 100 110
pF1KB5 WRVISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNA--TQPES
::::::::::: . :::: .: . :::::: ::. .:.::: :::.::: : :: ::
CCDS55 WRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYES
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 KVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNF
:::::::::::.:::.:::.:... :.: .:..::.:: ::::..::::::::::::::.
CCDS55 KVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 SVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQG
::::::: :.::.:: :::::::.::::::::::.:::::::::::::::::::::..:
CCDS55 SVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQD
180 190 200 210 220 230
240
pF1KB5 DEGDAGEGEN
:.: :::.:
CCDS55 DDG--GEGNN
240
>>CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 (246 aa)
initn: 1003 init1: 658 opt: 1150 Z-score: 1265.5 bits: 241.6 E(32554): 3.6e-64
Smith-Waterman score: 1150; 75.5% identity (89.0% similar) in 245 aa overlap (4-244:3-245)
10 20 30 40 50 60
pF1KB5 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
:. .:.:.:.::::::::::::.::::::: .. ::::.::::::::::::::::::
CCDS13 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSS
10 20 30 40 50
70 80 90 100 110
pF1KB5 WRVISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNAT--QPES
::::::::::: . :::: . : :::::: ::. .::::: ::::.:: : . : ::
CCDS13 WRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYES
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 KVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNF
:::::::::::.:::.:::::..:...: :. ::.:::::::..:::::::::::::::
CCDS13 KVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 SVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQG
::::::: :.::.:: ::: :::.::::::::::.:::::::::::::::::::::..:
CCDS13 SVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQD
180 190 200 210 220 230
240
pF1KB5 DEGDAGEGEN
.: ::::
CCDS13 EE--AGEGN
240
>>CCDS288.1 SFN gene_id:2810|Hs108|chr1 (248 aa)
initn: 1053 init1: 739 opt: 1060 Z-score: 1167.4 bits: 223.5 E(32554): 1.1e-58
Smith-Waterman score: 1060; 67.3% identity (89.0% similar) in 245 aa overlap (3-245:1-245)
10 20 30 40 50 60
pF1KB5 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
:... :.::::::::::::.:::: ::...:.:.::: :::::::::::::::..:..
CCDS28 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAA
10 20 30 40 50
70 80 90 100 110
pF1KB5 WRVISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKV
:::.::::::. : .:.: .:::::.:.::: .:. :: :::..:: .: . ::.:
CCDS28 WRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 FYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSV
:::::::::.:::.:::.::.:. ......:::::..:::::: ::.::::::::::::
CCDS28 FYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 FYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDE
:.::: ::::.: :::::.::::.:.: ::.:.::::::::::::::::::::..: :.:
CCDS28 FHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEE
180 190 200 210 220 230
240
pF1KB5 GDAGEGEN
: . :
CCDS28 GGEAPQEPQS
240
>>CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 (255 aa)
initn: 736 init1: 736 opt: 1024 Z-score: 1127.9 bits: 216.2 E(32554): 1.7e-56
Smith-Waterman score: 1024; 66.1% identity (83.7% similar) in 245 aa overlap (4-246:3-243)
10 20 30 40 50 60
pF1KB5 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
:. .:: .:::::::::::.:. .:: :. . ::. :::::::::::::.::::.:
CCDS11 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRAS
10 20 30 40 50
70 80 90 100 110
pF1KB5 WRVISSIEQKTERN--EKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKV
::.::::::: : . : : .: .:::. .:.::. :: :.:..:::.::: :. ::::
CCDS11 WRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 FYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSV
:: :::::: :::.: :.:.... .. :: ::. : .:. :. :::::::::::::::
CCDS11 FYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 FYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDE
:::::::::..:: :::.:::.::::::::.:::::::::::::::::::::::. :::
CCDS11 FYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD-
180 190 200 210 220 230
240
pF1KB5 GDAGEGEN
:: .:
CCDS11 ---GEEQNKEALQDVEDENQ
240 250
246 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:00:18 2016 done: Sat Nov 5 13:00:18 2016
Total Scan time: 2.280 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]