FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5413, 213 aa
  1>>>pF1KB5413 213 - 213 aa - 213 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.5709+/-0.000393; mu= 17.0288+/- 0.024
 mean_var=54.0297+/-11.333, 0's: 0 Z-trim(110.3): 34  B-trim: 695 in 1/49
 Lambda= 0.174485
 statistics sampled from 18612 (18633) to 18612 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.218), width:  16
 Scan time:  5.760

The best scores are:                                      opt bits E(85289)
NP_006310 (OMIM: 605893) CDP-diacylglycerol--inosi ( 213) 1413 363.7 1.2e-100
NP_001273514 (OMIM: 605893) CDP-diacylglycerol--in ( 168) 1012 262.7 2.5e-70
XP_005255095 (OMIM: 605893) PREDICTED: CDP-diacylg ( 237) 1012 262.8 3.3e-70
NP_001273515 (OMIM: 605893) CDP-diacylglycerol--in ( 148)  971 252.4 2.9e-67
XP_011527565 (OMIM: 608188) PREDICTED: cardiolipin ( 193)  128 40.2  0.0027
NP_001120930 (OMIM: 608188) cardiolipin synthase ( ( 202)  123 39.0  0.0067


>>NP_006310 (OMIM: 605893) CDP-diacylglycerol--inositol   (213 aa)
 initn: 1413 init1: 1413 opt: 1413  Z-score: 1927.7  bits: 363.7 E(85289): 1.2e-100
Smith-Waterman score: 1413; 100.0% identity (100.0% similar) in 213 aa overlap (1-213:1-213)

               10        20        30        40        50        60
pF1KB5 MPDENIFLFVPNLIGYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARALNQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MPDENIFLFVPNLIGYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARALNQG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 TRFGAMLDMLTDRCSTMCLLVNLALLYPGATLFFQISMSLDVASHWLHLHSSVVRGSESH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TRFGAMLDMLTDRCSTMCLLVNLALLYPGATLFFQISMSLDVASHWLHLHSSVVRGSESH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 KMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGLWVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGLWVTA
              130       140       150       160       170       180

              190       200       210   
pF1KB5 PIALLKSLISVIHLITAARNMAALDAADRAKKK
       :::::::::::::::::::::::::::::::::
NP_006 PIALLKSLISVIHLITAARNMAALDAADRAKKK
              190       200       210   

>>NP_001273514 (OMIM: 605893) CDP-diacylglycerol--inosit  (168 aa)
 initn: 1012 init1: 1012 opt: 1012  Z-score: 1383.6  bits: 262.7 E(85289): 2.5e-70
Smith-Waterman score: 1012; 100.0% identity (100.0% similar) in 154 aa overlap (60-213:15-168)

      30        40        50        60        70        80         
pF1KB5 PCCPLTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCSTMCLLVNLALLYPG
                                     ::::::::::::::::::::::::::::::
NP_001                 MPDENIFLFVPNLIGTRFGAMLDMLTDRCSTMCLLVNLALLYPG
                               10        20        30        40    

      90       100       110       120       130       140         
pF1KB5 ATLFFQISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLFFQISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNE
           50        60        70        80        90       100    

     150       160       170       180       190       200         
pF1KB5 LFYCLLYLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLITAARNMAALDAADR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFYCLLYLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLITAARNMAALDAADR
          110       120       130       140       150       160    

     210   
pF1KB5 AKKK
       ::::
NP_001 AKKK
           

>>XP_005255095 (OMIM: 605893) PREDICTED: CDP-diacylglyce  (237 aa)
 initn: 1040 init1: 1012 opt: 1012  Z-score: 1381.5  bits: 262.8 E(85289): 3.3e-70
Smith-Waterman score: 1012; 100.0% identity (100.0% similar) in 154 aa overlap (60-213:84-237)

      30        40        50        60        70        80         
pF1KB5 PCCPLTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCSTMCLLVNLALLYPG
                                     ::::::::::::::::::::::::::::::
XP_005 FTPCVRVINQIWAPVLHPLCHNSPCPPNLPGTRFGAMLDMLTDRCSTMCLLVNLALLYPG
            60        70        80        90       100       110   

      90       100       110       120       130       140         
pF1KB5 ATLFFQISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATLFFQISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNE
           120       130       140       150       160       170   

     150       160       170       180       190       200         
pF1KB5 LFYCLLYLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLITAARNMAALDAADR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFYCLLYLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLITAARNMAALDAADR
           180       190       200       210       220       230   

     210   
pF1KB5 AKKK
       ::::
XP_005 AKKK
           

>>NP_001273515 (OMIM: 605893) CDP-diacylglycerol--inosit  (148 aa)
 initn: 971 init1: 971 opt: 971  Z-score: 1328.6  bits: 252.4 E(85289): 2.9e-67
Smith-Waterman score: 971; 100.0% identity (100.0% similar) in 148 aa overlap (66-213:1-148)

          40        50        60        70        80        90     
pF1KB5 ASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCSTMCLLVNLALLYPGATLFFQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MLDMLTDRCSTMCLLVNLALLYPGATLFFQ
                                             10        20        30

         100       110       120       130       140       150     
pF1KB5 ISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLL
               40        50        60        70        80        90

         160       170       180       190       200       210   
pF1KB5 YLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLITAARNMAALDAADRAKKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLITAARNMAALDAADRAKKK
              100       110       120       130       140        

>>XP_011527565 (OMIM: 608188) PREDICTED: cardiolipin syn  (193 aa)
 initn: 109 init1:  54 opt: 128  Z-score: 180.1  bits: 40.2 E(85289): 0.0027
Smith-Waterman score: 128; 35.3% identity (61.2% similar) in 85 aa overlap (10-90:109-193)

                                    10        20        30         
pF1KB5                      MPDENIFLFVPNLIGYARIVFAIISFYFMPCCPLT-ASS
                                     .::.....:: .: .  :..    .. : .
XP_011 PAAGAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALG
       80        90       100       110       120       130        

       40        50         60        70        80          90     
pF1KB5 FYLLSGLLDAFDGHAARAL-NQGTRFGAMLDMLTDRCSTMCLLVNL--ALLYPGATLFFQ
        . :.:: : .::  ::   :: . .:. :: :.:.     : :.:  : : :::     
XP_011 VFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPGA     
      140       150       160       170       180       190        

         100       110       120       130       140       150     
pF1KB5 ISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLL

>>NP_001120930 (OMIM: 608188) cardiolipin synthase (CMP-  (202 aa)
 initn: 122 init1:  54 opt: 123  Z-score: 173.0  bits: 39.0 E(85289): 0.0067
Smith-Waterman score: 123; 31.7% identity (57.4% similar) in 101 aa overlap (1-97:1-101)

               10        20        30         40        50         
pF1KB5 MPDENIFLFVPNLIGYARIVFAIISFYFMPCCPLT-ASSFYLLSGLLDAFDGHAARAL-N
       ::. .    .::.....:: .: .  :..    .. : . . :.:: : .::  ::   :
NP_001 MPQYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWAN
               10        20        30        40        50        60

       60        70        80          90       100       110      
pF1KB5 QGTRFGAMLDMLTDRCSTMCLLVNL--ALLYPGATLFFQISMSLDVASHWLHLHSSVVRG
       : . .:. :: :.:.     : :.:  : : :    .. ::                   
NP_001 QRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPT
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB5 SESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGL
                                                                   
NP_001 PRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCFTAF
              130       140       150       160       170       180




213 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 12:44:15 2016 done: Sat Nov  5 12:44:16 2016
 Total Scan time:  5.760 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]