Result of FASTA (omim) for
pF1KB5408
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5408, 417 aa
1>>>pF1KB5408 417 - 417 aa - 417 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5801+/-0.000354; mu= 17.0576+/- 0.022
mean_var=111.1928+/-23.057, 0's: 0 Z-trim(116.5): 73 B-trim: 0 in 0/54
Lambda= 0.121629
statistics sampled from 27720 (27798) to 27720 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.326), width: 16
Scan time: 9.390
The best scores are: opt bits E(85289)
NP_037520 (OMIM: 606395) prolactin regulatory elem ( 417) 2803 502.8 6.5e-142
NP_001317413 (OMIM: 606395) prolactin regulatory e ( 345) 2336 420.8 2.6e-117
NP_001317415 (OMIM: 606395) prolactin regulatory e ( 350) 2250 405.7 9.3e-113
NP_001317416 (OMIM: 606395) prolactin regulatory e ( 292) 1674 304.5 2.2e-82
NP_001317414 (OMIM: 606395) prolactin regulatory e ( 359) 1674 304.6 2.5e-82
>>NP_037520 (OMIM: 606395) prolactin regulatory element- (417 aa)
initn: 2803 init1: 2803 opt: 2803 Z-score: 2668.8 bits: 502.8 E(85289): 6.5e-142
Smith-Waterman score: 2803; 100.0% identity (100.0% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KB5 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 LLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL
370 380 390 400 410
>>NP_001317413 (OMIM: 606395) prolactin regulatory eleme (345 aa)
initn: 2336 init1: 2336 opt: 2336 Z-score: 2227.0 bits: 420.8 E(85289): 2.6e-117
Smith-Waterman score: 2336; 100.0% identity (100.0% similar) in 345 aa overlap (73-417:1-345)
50 60 70 80 90 100
pF1KB5 NGVHFLQLELINGRLSASLLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQG
::::::::::::::::::::::::::::::
NP_001 MNLALAGDILAAGQDAHCQLLRFQAHQQQG
10 20 30
110 120 130 140 150 160
pF1KB5 NKAEKAGSKEQGPRQRKGAAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKAEKAGSKEQGPRQRKGAAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCF
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB5 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVW
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB5 QKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYL
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB5 TAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAH
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB5 GIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLI
280 290 300 310 320 330
410
pF1KB5 IVTILLLQSAFPGFL
:::::::::::::::
NP_001 IVTILLLQSAFPGFL
340
>>NP_001317415 (OMIM: 606395) prolactin regulatory eleme (350 aa)
initn: 2276 init1: 2250 opt: 2250 Z-score: 2145.3 bits: 405.7 E(85289): 9.3e-113
Smith-Waterman score: 2250; 99.1% identity (99.7% similar) in 336 aa overlap (1-336:1-336)
10 20 30 40 50 60
pF1KB5 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE
::::::::::::::::::::::::::::::::: ..
NP_001 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQGVFLCGSCSCCVSGLLL
310 320 330 340 350
370 380 390 400 410
pF1KB5 LLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL
>>NP_001317416 (OMIM: 606395) prolactin regulatory eleme (292 aa)
initn: 1811 init1: 1674 opt: 1674 Z-score: 1600.0 bits: 304.5 E(85289): 2.2e-82
Smith-Waterman score: 1699; 81.8% identity (82.4% similar) in 336 aa overlap (1-336:1-278)
10 20 30 40 50 60
pF1KB5 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH
::::::::::
NP_001 SSTPYRYQAC--------------------------------------------------
250
310 320 330 340 350 360
pF1KB5 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE
::::::::::::::::::::::::: ..
NP_001 --------SESGTFLGLGTVTGSVAIYIAFSLQGVFLCGSCSCCVSGLLL
260 270 280 290
370 380 390 400 410
pF1KB5 LLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL
>>NP_001317414 (OMIM: 606395) prolactin regulatory eleme (359 aa)
initn: 2364 init1: 1674 opt: 1674 Z-score: 1598.9 bits: 304.6 E(85289): 2.5e-82
Smith-Waterman score: 2252; 86.1% identity (86.1% similar) in 417 aa overlap (1-417:1-359)
10 20 30 40 50 60
pF1KB5 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH
::::::::::
NP_001 SSTPYRYQAC--------------------------------------------------
250
310 320 330 340 350 360
pF1KB5 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------SESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE
260 270 280 290 300
370 380 390 400 410
pF1KB5 LLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL
310 320 330 340 350
417 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:58:54 2016 done: Sat Nov 5 00:58:55 2016
Total Scan time: 9.390 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]