Result of FASTA (omim) for
pF1KB5356
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5356, 448 aa
1>>>pF1KB5356 448 - 448 aa - 448 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4765+/-0.000329; mu= 18.0898+/- 0.021
mean_var=84.2489+/-17.463, 0's: 0 Z-trim(116.3): 22 B-trim: 1178 in 1/57
Lambda= 0.139731
statistics sampled from 27330 (27352) to 27330 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.321), width: 16
Scan time: 9.770
The best scores are: opt bits E(85289)
XP_005273256 (OMIM: 600759,606889,613697) PREDICTE ( 448) 2979 610.2 3.4e-174
XP_016857324 (OMIM: 600759,606889,613697) PREDICTE ( 448) 2979 610.2 3.4e-174
NP_000438 (OMIM: 600759,606889,613697) presenilin- ( 448) 2979 610.2 3.4e-174
NP_036618 (OMIM: 600759,606889,613697) presenilin- ( 447) 2961 606.6 4.2e-173
XP_016857325 (OMIM: 600759,606889,613697) PREDICTE ( 447) 2961 606.6 4.2e-173
XP_011535276 (OMIM: 104311,172700,600274,607822,61 ( 463) 1309 273.6 7.7e-73
NP_015557 (OMIM: 104311,172700,600274,607822,61369 ( 463) 1309 273.6 7.7e-73
XP_005267923 (OMIM: 104311,172700,600274,607822,61 ( 463) 1309 273.6 7.7e-73
XP_011535275 (OMIM: 104311,172700,600274,607822,61 ( 463) 1309 273.6 7.7e-73
XP_011535273 (OMIM: 104311,172700,600274,607822,61 ( 467) 1309 273.6 7.8e-73
XP_005267921 (OMIM: 104311,172700,600274,607822,61 ( 467) 1309 273.6 7.8e-73
NP_000012 (OMIM: 104311,172700,600274,607822,61369 ( 467) 1309 273.6 7.8e-73
XP_011535274 (OMIM: 104311,172700,600274,607822,61 ( 467) 1309 273.6 7.8e-73
>>XP_005273256 (OMIM: 600759,606889,613697) PREDICTED: p (448 aa)
initn: 2979 init1: 2979 opt: 2979 Z-score: 3248.3 bits: 610.2 E(85289): 3.4e-174
Smith-Waterman score: 2979; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448)
10 20 30 40 50 60
pF1KB5 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
370 380 390 400 410 420
430 440
pF1KB5 TFGLIFYFSTDNLVRPFMDTLASHQLYI
::::::::::::::::::::::::::::
XP_005 TFGLIFYFSTDNLVRPFMDTLASHQLYI
430 440
>>XP_016857324 (OMIM: 600759,606889,613697) PREDICTED: p (448 aa)
initn: 2979 init1: 2979 opt: 2979 Z-score: 3248.3 bits: 610.2 E(85289): 3.4e-174
Smith-Waterman score: 2979; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448)
10 20 30 40 50 60
pF1KB5 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
370 380 390 400 410 420
430 440
pF1KB5 TFGLIFYFSTDNLVRPFMDTLASHQLYI
::::::::::::::::::::::::::::
XP_016 TFGLIFYFSTDNLVRPFMDTLASHQLYI
430 440
>>NP_000438 (OMIM: 600759,606889,613697) presenilin-2 is (448 aa)
initn: 2979 init1: 2979 opt: 2979 Z-score: 3248.3 bits: 610.2 E(85289): 3.4e-174
Smith-Waterman score: 2979; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448)
10 20 30 40 50 60
pF1KB5 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
370 380 390 400 410 420
430 440
pF1KB5 TFGLIFYFSTDNLVRPFMDTLASHQLYI
::::::::::::::::::::::::::::
NP_000 TFGLIFYFSTDNLVRPFMDTLASHQLYI
430 440
>>NP_036618 (OMIM: 600759,606889,613697) presenilin-2 is (447 aa)
initn: 2164 init1: 2164 opt: 2961 Z-score: 3228.7 bits: 606.6 E(85289): 4.2e-173
Smith-Waterman score: 2961; 99.8% identity (99.8% similar) in 448 aa overlap (1-448:1-447)
10 20 30 40 50 60
pF1KB5 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
NP_036 TVGMAKLDPSSQGALQLPYDPEME-DSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
310 320 330 340 350
370 380 390 400 410 420
pF1KB5 KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
360 370 380 390 400 410
430 440
pF1KB5 TFGLIFYFSTDNLVRPFMDTLASHQLYI
::::::::::::::::::::::::::::
NP_036 TFGLIFYFSTDNLVRPFMDTLASHQLYI
420 430 440
>>XP_016857325 (OMIM: 600759,606889,613697) PREDICTED: p (447 aa)
initn: 2164 init1: 2164 opt: 2961 Z-score: 3228.7 bits: 606.6 E(85289): 4.2e-173
Smith-Waterman score: 2961; 99.8% identity (99.8% similar) in 448 aa overlap (1-448:1-447)
10 20 30 40 50 60
pF1KB5 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 TVGMAKLDPSSQGALQLPYDPEME-DSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
310 320 330 340 350
370 380 390 400 410 420
pF1KB5 KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
360 370 380 390 400 410
430 440
pF1KB5 TFGLIFYFSTDNLVRPFMDTLASHQLYI
::::::::::::::::::::::::::::
XP_016 TFGLIFYFSTDNLVRPFMDTLASHQLYI
420 430 440
>>XP_011535276 (OMIM: 104311,172700,600274,607822,613694 (463 aa)
initn: 1828 init1: 1291 opt: 1309 Z-score: 1428.7 bits: 273.6 E(85289): 7.7e-73
Smith-Waterman score: 1821; 65.3% identity (79.3% similar) in 464 aa overlap (24-448:3-463)
10 20 30 40 50 60
pF1KB5 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
: :.: : .. : ::.. . ...:.: :..
XP_011 MTELPAPLSYFQNAQMSEDNHLSN---TNDNRERQEHND
10 20 30
70 80 90 100
pF1KB5 DRYVCSGVP---GRPPG-----------LEEELTLKYGAKHVIMLFVPVTLCMIVVVATI
: . : ::: : .:::::::::::::::::::::::.::::::
XP_011 RRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB5 KSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYK
::: :::.:.:::::::::::: .:::: :.:.::. :::::::::::.:::::::::::
XP_011 KSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYK
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB5 FIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLV
::.:::.:::.:::.:..::::::.::::::.:: :. : .::::.:::. :::::::
XP_011 VIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLR
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB5 LQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNE
::::::::::::::::::::::::.::.::..::::::::::::::::::::::::::::
XP_011 LQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNE
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB5 PIFPALIYSSAMVWTVGMAKLDPSSQGALQL--PYDPE-MEEDSYDSFGEPS---YPEVF
.::::::::.::: :.::. :: .: .. :. : :..: :. .: . . : .
XP_011 TLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEW
280 290 300 310 320 330
350 360 370 380
pF1KB5 EPPLTGYPG------------EEL-------EEEEERGVKLGLGDFIFYSVLVGKAAATG
: .. : .:: :. ::::::::::::::::::::::.::.
XP_011 EAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATA
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB5 SGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTL
:::::::.::::::::::::::::::.::::::::::::::::.:::.:: ::.:::: :
XP_011 SGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQL
400 410 420 430 440 450
pF1KB5 ASHQLYI
: ::.::
XP_011 AFHQFYI
460
>>NP_015557 (OMIM: 104311,172700,600274,607822,613694,61 (463 aa)
initn: 1828 init1: 1291 opt: 1309 Z-score: 1428.7 bits: 273.6 E(85289): 7.7e-73
Smith-Waterman score: 1821; 65.3% identity (79.3% similar) in 464 aa overlap (24-448:3-463)
10 20 30 40 50 60
pF1KB5 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
: :.: : .. : ::.. . ...:.: :..
NP_015 MTELPAPLSYFQNAQMSEDNHLSN---TNDNRERQEHND
10 20 30
70 80 90 100
pF1KB5 DRYVCSGVP---GRPPG-----------LEEELTLKYGAKHVIMLFVPVTLCMIVVVATI
: . : ::: : .:::::::::::::::::::::::.::::::
NP_015 RRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB5 KSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYK
::: :::.:.:::::::::::: .:::: :.:.::. :::::::::::.:::::::::::
NP_015 KSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYK
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB5 FIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLV
::.:::.:::.:::.:..::::::.::::::.:: :. : .::::.:::. :::::::
NP_015 VIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLR
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB5 LQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNE
::::::::::::::::::::::::.::.::..::::::::::::::::::::::::::::
NP_015 LQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNE
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB5 PIFPALIYSSAMVWTVGMAKLDPSSQGALQL--PYDPE-MEEDSYDSFGEPS---YPEVF
.::::::::.::: :.::. :: .: .. :. : :..: :. .: . . : .
NP_015 TLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEW
280 290 300 310 320 330
350 360 370 380
pF1KB5 EPPLTGYPG------------EEL-------EEEEERGVKLGLGDFIFYSVLVGKAAATG
: .. : .:: :. ::::::::::::::::::::::.::.
NP_015 EAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATA
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB5 SGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTL
:::::::.::::::::::::::::::.::::::::::::::::.:::.:: ::.:::: :
NP_015 SGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQL
400 410 420 430 440 450
pF1KB5 ASHQLYI
: ::.::
NP_015 AFHQFYI
460
>>XP_005267923 (OMIM: 104311,172700,600274,607822,613694 (463 aa)
initn: 1828 init1: 1291 opt: 1309 Z-score: 1428.7 bits: 273.6 E(85289): 7.7e-73
Smith-Waterman score: 1821; 65.3% identity (79.3% similar) in 464 aa overlap (24-448:3-463)
10 20 30 40 50 60
pF1KB5 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
: :.: : .. : ::.. . ...:.: :..
XP_005 MTELPAPLSYFQNAQMSEDNHLSN---TNDNRERQEHND
10 20 30
70 80 90 100
pF1KB5 DRYVCSGVP---GRPPG-----------LEEELTLKYGAKHVIMLFVPVTLCMIVVVATI
: . : ::: : .:::::::::::::::::::::::.::::::
XP_005 RRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB5 KSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYK
::: :::.:.:::::::::::: .:::: :.:.::. :::::::::::.:::::::::::
XP_005 KSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYK
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB5 FIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLV
::.:::.:::.:::.:..::::::.::::::.:: :. : .::::.:::. :::::::
XP_005 VIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLR
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB5 LQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNE
::::::::::::::::::::::::.::.::..::::::::::::::::::::::::::::
XP_005 LQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNE
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB5 PIFPALIYSSAMVWTVGMAKLDPSSQGALQL--PYDPE-MEEDSYDSFGEPS---YPEVF
.::::::::.::: :.::. :: .: .. :. : :..: :. .: . . : .
XP_005 TLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEW
280 290 300 310 320 330
350 360 370 380
pF1KB5 EPPLTGYPG------------EEL-------EEEEERGVKLGLGDFIFYSVLVGKAAATG
: .. : .:: :. ::::::::::::::::::::::.::.
XP_005 EAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATA
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB5 SGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTL
:::::::.::::::::::::::::::.::::::::::::::::.:::.:: ::.:::: :
XP_005 SGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQL
400 410 420 430 440 450
pF1KB5 ASHQLYI
: ::.::
XP_005 AFHQFYI
460
>>XP_011535275 (OMIM: 104311,172700,600274,607822,613694 (463 aa)
initn: 1828 init1: 1291 opt: 1309 Z-score: 1428.7 bits: 273.6 E(85289): 7.7e-73
Smith-Waterman score: 1821; 65.3% identity (79.3% similar) in 464 aa overlap (24-448:3-463)
10 20 30 40 50 60
pF1KB5 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
: :.: : .. : ::.. . ...:.: :..
XP_011 MTELPAPLSYFQNAQMSEDNHLSN---TNDNRERQEHND
10 20 30
70 80 90 100
pF1KB5 DRYVCSGVP---GRPPG-----------LEEELTLKYGAKHVIMLFVPVTLCMIVVVATI
: . : ::: : .:::::::::::::::::::::::.::::::
XP_011 RRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB5 KSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYK
::: :::.:.:::::::::::: .:::: :.:.::. :::::::::::.:::::::::::
XP_011 KSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYK
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB5 FIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLV
::.:::.:::.:::.:..::::::.::::::.:: :. : .::::.:::. :::::::
XP_011 VIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLR
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB5 LQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNE
::::::::::::::::::::::::.::.::..::::::::::::::::::::::::::::
XP_011 LQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNE
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB5 PIFPALIYSSAMVWTVGMAKLDPSSQGALQL--PYDPE-MEEDSYDSFGEPS---YPEVF
.::::::::.::: :.::. :: .: .. :. : :..: :. .: . . : .
XP_011 TLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEW
280 290 300 310 320 330
350 360 370 380
pF1KB5 EPPLTGYPG------------EEL-------EEEEERGVKLGLGDFIFYSVLVGKAAATG
: .. : .:: :. ::::::::::::::::::::::.::.
XP_011 EAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATA
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB5 SGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTL
:::::::.::::::::::::::::::.::::::::::::::::.:::.:: ::.:::: :
XP_011 SGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQL
400 410 420 430 440 450
pF1KB5 ASHQLYI
: ::.::
XP_011 AFHQFYI
460
>>XP_011535273 (OMIM: 104311,172700,600274,607822,613694 (467 aa)
initn: 1864 init1: 1291 opt: 1309 Z-score: 1428.6 bits: 273.6 E(85289): 7.8e-73
Smith-Waterman score: 1841; 65.7% identity (79.4% similar) in 466 aa overlap (24-448:3-467)
10 20 30 40 50 60
pF1KB5 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
: :.: : .. : ::.. . :::..... .:
XP_011 MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHN
10 20 30
70 80 90 100
pF1KB5 DRYVCSGVP-----GRPPG-----------LEEELTLKYGAKHVIMLFVPVTLCMIVVVA
:: : : ::: : .:::::::::::::::::::::::.::::
XP_011 DRRSL-GHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVA
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB5 TIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRC
::::: :::.:.:::::::::::: .:::: :.:.::. :::::::::::.:::::::::
XP_011 TIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRC
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB5 YKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGP
:: ::.:::.:::.:::.:..::::::.::::::.:: :. : .::::.:::. ::::::
XP_011 YKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGP
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB5 LVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQER
: ::::::::::::::::::::::::.::.::..::::::::::::::::::::::::::
XP_011 LRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQER
220 230 240 250 260 270
290 300 310 320 330
pF1KB5 NEPIFPALIYSSAMVWTVGMAKLDPSSQGALQL--PYDPE-MEEDSYDSFGEPS---YPE
:: .::::::::.::: :.::. :: .: .. :. : :..: :. .: . . :
XP_011 NETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSE
280 290 300 310 320 330
340 350 360 370
pF1KB5 VFEPPLTGYPG------------EEL-------EEEEERGVKLGLGDFIFYSVLVGKAAA
.: .. : .:: :. ::::::::::::::::::::::.:
XP_011 EWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASA
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB5 TGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMD
:.:::::::.::::::::::::::::::.::::::::::::::::.:::.:: ::.::::
XP_011 TASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMD
400 410 420 430 440 450
440
pF1KB5 TLASHQLYI
:: ::.::
XP_011 QLAFHQFYI
460
448 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:48:58 2016 done: Fri Nov 4 21:48:59 2016
Total Scan time: 9.770 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]