FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5332, 275 aa
  1>>>pF1KB5332 275 - 275 aa - 275 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2059+/-0.000353; mu= 16.3906+/- 0.022
 mean_var=69.8319+/-14.262, 0's: 0 Z-trim(114.2): 12  B-trim: 0 in 0/53
 Lambda= 0.153478
 statistics sampled from 23865 (23871) to 23865 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.28), width:  16
 Scan time:  7.020

The best scores are:                                      opt bits E(85289)
NP_116558 (OMIM: 180663) DNA-directed RNA polymera ( 275) 1842 416.6 2.5e-116
XP_011513302 (OMIM: 248390,610060,616494) PREDICTE ( 307)  344 85.0 1.9e-16
NP_001305805 (OMIM: 248390,610060,616494) DNA-dire ( 342)  344 85.0 2.1e-16
NP_976035 (OMIM: 248390,610060,616494) DNA-directe ( 346)  344 85.0 2.1e-16


>>NP_116558 (OMIM: 180663) DNA-directed RNA polymerase I  (275 aa)
 initn: 1842 init1: 1842 opt: 1842  Z-score: 2209.6  bits: 416.6 E(85289): 2.5e-116
Smith-Waterman score: 1842; 100.0% identity (100.0% similar) in 275 aa overlap (1-275:1-275)

               10        20        30        40        50        60
pF1KB5 MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 ISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 GVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 GVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLR
              190       200       210       220       230       240

              250       260       270     
pF1KB5 PETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
       :::::::::::::::::::::::::::::::::::
NP_116 PETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
              250       260       270     

>>XP_011513302 (OMIM: 248390,610060,616494) PREDICTED: D  (307 aa)
 initn: 352 init1: 185 opt: 344  Z-score: 416.3  bits: 85.0 E(85289): 1.9e-16
Smith-Waterman score: 344; 33.7% identity (63.4% similar) in 205 aa overlap (9-202:51-251)

                                     10        20        30        
pF1KB5                       MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVF
                                     : .... .....: . . : :.::..::..
XP_011 VRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRIL
               30        40        50        60        70        80

       40        50        60        70        80        90        
pF1KB5 IAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECS
       .:::: .:.. : .  :.:...::..::::::::. .:    .:   :.   ::     .
XP_011 LAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADP---RLFEYRNQGDEEGTEIDT
               90       100       110          120       130       

      100       110          120             130       140         
pF1KB5 VEFTLDVRCNEDQTRHVTSRD---LISNSPRV------IPVTSRNRDNDPNDYVE--QDD
       ..: :.:::...      : :   :  :          ::. ..  :  :.  ..  .::
XP_011 LQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGNQA-DLFPEGTIRPVHDD
       140       150       160       170       180        190      

       150       160       170       180       190       200       
pF1KB5 ILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSE
       :::..:: :::. :  .  ::.::.:::..:.: ....  :: .: . :  .  :     
XP_011 ILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRC
        200       210       220       230       240       250      

       210       220       230       240       250       260       
pF1KB5 YSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEI
                                                                   
XP_011 FSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLARVRDHYI         
        260       270       280       290       300                

>>NP_001305805 (OMIM: 248390,610060,616494) DNA-directed  (342 aa)
 initn: 352 init1: 185 opt: 344  Z-score: 415.6  bits: 85.0 E(85289): 2.1e-16
Smith-Waterman score: 344; 33.7% identity (63.4% similar) in 205 aa overlap (9-202:51-251)

                                     10        20        30        
pF1KB5                       MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVF
                                     : .... .....: . . : :.::..::..
NP_001 VRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRIL
               30        40        50        60        70        80

       40        50        60        70        80        90        
pF1KB5 IAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECS
       .:::: .:.. : .  :.:...::..::::::::. .:    .:   :.   ::     .
NP_001 LAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADP---RLFEYRNQGDEEGTEIDT
               90       100       110          120       130       

      100       110          120             130       140         
pF1KB5 VEFTLDVRCNEDQTRHVTSRD---LISNSPRV------IPVTSRNRDNDPNDYVE--QDD
       ..: :.:::...      : :   :  :          ::. ..  :  :.  ..  .::
NP_001 LQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGNQA-DLFPEGTIRPVHDD
       140       150       160       170       180        190      

       150       160       170       180       190       200       
pF1KB5 ILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSE
       :::..:: :::. :  .  ::.::.:::..:.: ....  :: .: . :  .  :     
NP_001 ILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRC
        200       210       220       230       240       250      

       210       220       230       240       250       260       
pF1KB5 YSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEI
                                                                   
NP_001 FSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLARVRDHYICKKDLLAAV
        260       270       280       290       300       310      

>>NP_976035 (OMIM: 248390,610060,616494) DNA-directed RN  (346 aa)
 initn: 354 init1: 185 opt: 344  Z-score: 415.5  bits: 85.0 E(85289): 2.1e-16
Smith-Waterman score: 344; 33.7% identity (63.4% similar) in 205 aa overlap (9-202:51-251)

                                     10        20        30        
pF1KB5                       MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVF
                                     : .... .....: . . : :.::..::..
NP_976 VRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRIL
               30        40        50        60        70        80

       40        50        60        70        80        90        
pF1KB5 IAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECS
       .:::: .:.. : .  :.:...::..::::::::. .:    .:   :.   ::     .
NP_976 LAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADP---RLFEYRNQGDEEGTEIDT
               90       100       110          120       130       

      100       110          120             130       140         
pF1KB5 VEFTLDVRCNEDQTRHVTSRD---LISNSPRV------IPVTSRNRDNDPNDYVE--QDD
       ..: :.:::...      : :   :  :          ::. ..  :  :.  ..  .::
NP_976 LQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGNQA-DLFPEGTIRPVHDD
       140       150       160       170       180        190      

       150       160       170       180       190       200       
pF1KB5 ILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSE
       :::..:: :::. :  .  ::.::.:::..:.: ....  :: .: . :  .  :     
NP_976 ILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRC
        200       210       220       230       240       250      

       210       220       230       240       250       260       
pF1KB5 YSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEI
                                                                   
NP_976 FSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLARVRDHYIFSVESTGVL
        260       270       280       290       300       310      




275 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:38:03 2016 done: Fri Nov  4 03:38:04 2016
 Total Scan time:  7.020 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]