Result of FASTA (omim) for
pF1KB5297
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5297, 300 aa
1>>>pF1KB5297 300 - 300 aa - 300 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4232+/-0.000414; mu= 20.4383+/- 0.026
mean_var=59.8647+/-11.919, 0's: 0 Z-trim(109.5): 156 B-trim: 0 in 0/52
Lambda= 0.165763
statistics sampled from 17516 (17684) to 17516 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.566), E-opt: 0.2 (0.207), width: 16
Scan time: 6.240
The best scores are: opt bits E(85289)
NP_057329 (OMIM: 612831) estradiol 17-beta-dehydro ( 300) 1919 467.6 1.4e-131
NP_835236 (OMIM: 612127) 17-beta-hydroxysteroid de ( 300) 1287 316.4 4.3e-86
XP_011530323 (OMIM: 612831) PREDICTED: estradiol 1 ( 151) 961 238.2 7.6e-63
NP_001129702 (OMIM: 612127) 17-beta-hydroxysteroid ( 264) 826 206.1 6e-53
NP_620419 (OMIM: 608989) epidermal retinol dehydro ( 309) 792 198.1 1.9e-50
NP_001304978 (OMIM: 608989) epidermal retinol dehy ( 318) 787 196.9 4.4e-50
NP_004744 (OMIM: 612830) short-chain dehydrogenase ( 302) 597 151.4 2e-36
NP_742034 (OMIM: 607599) retinol dehydrogenase 10 ( 341) 572 145.5 1.4e-34
NP_001311299 (OMIM: 612830) short-chain dehydrogen ( 217) 443 114.5 1.9e-25
XP_016858298 (OMIM: 612830) PREDICTED: short-chain ( 217) 443 114.5 1.9e-25
NP_001306154 (OMIM: 612830) short-chain dehydrogen ( 217) 443 114.5 1.9e-25
NP_057113 (OMIM: 612833) dehydrogenase/reductase S ( 339) 331 87.8 3.1e-17
XP_016876857 (OMIM: 612833) PREDICTED: dehydrogena ( 404) 331 87.9 3.6e-17
XP_011522088 (OMIM: 616160) PREDICTED: dehydrogena ( 334) 330 87.6 3.6e-17
NP_001317088 (OMIM: 616160) dehydrogenase/reductas ( 310) 329 87.3 4.1e-17
NP_056325 (OMIM: 616160) dehydrogenase/reductase S ( 325) 329 87.3 4.2e-17
XP_016879915 (OMIM: 616160) PREDICTED: dehydrogena ( 325) 329 87.3 4.2e-17
NP_001309209 (OMIM: 612833) dehydrogenase/reductas ( 289) 328 87.1 4.6e-17
XP_005256652 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 329 87.4 4.7e-17
XP_016879914 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 329 87.4 4.7e-17
NP_005516 (OMIM: 600713,614662) corticosteroid 11- ( 292) 321 85.4 1.5e-16
NP_861420 (OMIM: 600713,614662) corticosteroid 11- ( 292) 321 85.4 1.5e-16
NP_001193670 (OMIM: 600713,614662) corticosteroid ( 292) 321 85.4 1.5e-16
NP_001304979 (OMIM: 608989) epidermal retinol dehy ( 265) 303 81.1 2.7e-15
XP_011515781 (OMIM: 608989) PREDICTED: epidermal r ( 274) 303 81.1 2.8e-15
NP_000851 (OMIM: 119900,259100,601688) 15-hydroxyp ( 266) 297 79.6 7.3e-15
NP_077284 (OMIM: 616159) dehydrogenase/reductase S ( 260) 291 78.2 1.9e-14
XP_005257715 (OMIM: 616159) PREDICTED: dehydrogena ( 229) 280 75.5 1.1e-13
NP_057226 (OMIM: 609574) very-long-chain 3-oxoacyl ( 312) 270 73.2 7.2e-13
NP_066284 (OMIM: 611596) dehydrogenase/reductase S ( 278) 267 72.5 1.1e-12
XP_016873370 (OMIM: 609574) PREDICTED: very-long-c ( 280) 259 70.6 4.1e-12
NP_001317148 (OMIM: 109684) estradiol 17-beta-dehy ( 329) 257 70.1 6.5e-12
XP_011523031 (OMIM: 109684) PREDICTED: estradiol 1 ( 384) 254 69.5 1.2e-11
NP_001135742 (OMIM: 612131) dehydrogenase/reductas ( 319) 252 68.9 1.5e-11
XP_011508777 (OMIM: 612131) PREDICTED: dehydrogena ( 319) 252 68.9 1.5e-11
NP_954674 (OMIM: 612131) dehydrogenase/reductase S ( 319) 252 68.9 1.5e-11
NP_001135743 (OMIM: 612131) dehydrogenase/reductas ( 319) 252 68.9 1.5e-11
XP_006711099 (OMIM: 612830) PREDICTED: short-chain ( 186) 249 68.0 1.6e-11
NP_001276692 (OMIM: 612131) dehydrogenase/reductas ( 379) 252 69.0 1.6e-11
NP_000404 (OMIM: 109684) estradiol 17-beta-dehydro ( 328) 249 68.2 2.4e-11
NP_932349 (OMIM: 615196) dehydrogenase/reductase S ( 232) 246 67.4 3.1e-11
NP_001099041 (OMIM: 616161) dehydrogenase/reductas ( 311) 246 67.5 3.9e-11
XP_011523032 (OMIM: 109684) PREDICTED: estradiol 1 ( 383) 244 67.1 6.3e-11
NP_005785 (OMIM: 615194) dehydrogenase/reductase S ( 280) 238 65.5 1.3e-10
XP_005267306 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 238 65.5 1.3e-10
XP_006720064 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 238 65.5 1.3e-10
NP_878912 (OMIM: 615194) dehydrogenase/reductase S ( 300) 238 65.6 1.4e-10
NP_056540 (OMIM: 608575) retinol dehydrogenase 8 [ ( 331) 237 65.4 1.8e-10
NP_001139288 (OMIM: 119900,259100,601688) 15-hydro ( 178) 229 63.2 4.3e-10
XP_005269264 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 228 63.2 7.7e-10
>>NP_057329 (OMIM: 612831) estradiol 17-beta-dehydrogena (300 aa)
initn: 1919 init1: 1919 opt: 1919 Z-score: 2483.5 bits: 467.6 E(85289): 1.4e-131
Smith-Waterman score: 1919; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300)
10 20 30 40 50 60
pF1KB5 MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 EVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ
250 260 270 280 290 300
>>NP_835236 (OMIM: 612127) 17-beta-hydroxysteroid dehydr (300 aa)
initn: 1271 init1: 1271 opt: 1287 Z-score: 1666.6 bits: 316.4 E(85289): 4.3e-86
Smith-Waterman score: 1287; 63.7% identity (85.7% similar) in 300 aa overlap (1-300:1-300)
10 20 30 40 50 60
pF1KB5 MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLK
:...:.::::: .: :::.::.:::.:::::.::::::::::::::: :.::::: .
NP_835 MNIILEILLLLITIIYSYLESLVKFFIPQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNN
: ::::::::.:.:::::.:. ::. .:..::::::::.:: : ..:: :.:::.:.:::
NP_835 SILVLWDINKRGVEETAAECRKLGVTAHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVP
::.:: .::..:.: .: ::::::.:.::: :::.::.: . ::::::::::. :: ..:
NP_835 AGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPE
.:. ::::::::::::. ::.:: :: ::.::.:::: :::::: ::::: : :.:: .
NP_835 YLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 EVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ
::: :. ::::..::::.:: : .. :...:::: :.:.: ...:.::.:.:.: .
NP_835 EVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNIQFEAVVGHKIKMK
250 260 270 280 290 300
>>XP_011530323 (OMIM: 612831) PREDICTED: estradiol 17-be (151 aa)
initn: 961 init1: 961 opt: 961 Z-score: 1249.2 bits: 238.2 E(85289): 7.6e-63
Smith-Waterman score: 961; 100.0% identity (100.0% similar) in 150 aa overlap (1-150:1-150)
10 20 30 40 50 60
pF1KB5 MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVP
::::::::::::::::::::::::::::::
XP_011 AGVVYTSDLFATQDPQIEKTFEVNVLAHFWR
130 140 150
>>NP_001129702 (OMIM: 612127) 17-beta-hydroxysteroid deh (264 aa)
initn: 1127 init1: 826 opt: 826 Z-score: 1071.5 bits: 206.1 E(85289): 6e-53
Smith-Waterman score: 1053; 56.7% identity (75.0% similar) in 300 aa overlap (1-300:1-264)
10 20 30 40 50 60
pF1KB5 MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLK
:...:.::::: .: :::.::.:::.:::::.::::::::::::::: :.::::: .
NP_001 MNIILEILLLLITIIYSYLESLVKFFIPQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNN
: :::::::: :: :.:::.:.:::
NP_001 SILVLWDINK------------------------------------VKKEVGDVTIVVNN
70 80
130 140 150 160 170 180
pF1KB5 AGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVP
::.:: .::..:.: .: ::::::.:.::: :::.::.: . ::::::::::. :: ..:
NP_001 AGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIP
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB5 FLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPE
.:. ::::::::::::. ::.:: :: ::.::.:::: :::::: ::::: : :.:: .
NP_001 YLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETD
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB5 EVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ
::: :. ::::..::::.:: : .. :...:::: :.:.: ...:.::.:.:.: .
NP_001 EVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNIQFEAVVGHKIKMK
210 220 230 240 250 260
>>NP_620419 (OMIM: 608989) epidermal retinol dehydrogena (309 aa)
initn: 789 init1: 470 opt: 792 Z-score: 1026.7 bits: 198.1 E(85289): 1.9e-50
Smith-Waterman score: 792; 47.7% identity (74.2% similar) in 260 aa overlap (19-274:23-282)
10 20 30 40 50
pF1KB5 MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEF
::... ..:: ::.:.:::::::::: :.::: : .:
NP_620 MSFNLQSSKKLFIFLGKSLFSLLEAMIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 AKLKSKLVLWDINKHGLEETAAKCKGLGA-KVHTFVVDCSNREDIYSSAKKVKAEIGDVS
:.: : ::::::::.: ::: . :: .::... :::..: .: : .:: :.::::
NP_620 ARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 ILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAG
::.::::.: . .. : .::.:.:: ::.:: ::::::: :.:::.: ..:.::
NP_620 ILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPST---S
.: : ::.::::: :: ... : . . :.::: .:: :..::.... .: :
NP_620 LSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKTGMFEGCTTGCPS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 LGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAV
: : :::. .:......:: :. ....:. . :. :. .::
NP_620 LLPILEPKYAVEKIVEAILQEKMYLYMPKLLYFMMFLKSFLPLKTGLLIADYLGILHAMD
250 260 270 280 290 300
300
pF1KB5 IGYKMKAQ
NP_620 GFVDQKKKL
>>NP_001304978 (OMIM: 608989) epidermal retinol dehydrog (318 aa)
initn: 784 init1: 470 opt: 787 Z-score: 1020.1 bits: 196.9 E(85289): 4.4e-50
Smith-Waterman score: 787; 47.7% identity (74.4% similar) in 258 aa overlap (19-272:23-280)
10 20 30 40 50
pF1KB5 MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEF
::... ..:: ::.:.:::::::::: :.::: : .:
NP_001 MSFNLQSSKKLFIFLGKSLFSLLEAMIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 AKLKSKLVLWDINKHGLEETAAKCKGLGA-KVHTFVVDCSNREDIYSSAKKVKAEIGDVS
:.: : ::::::::.: ::: . :: .::... :::..: .: : .:: :.::::
NP_001 ARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 ILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAG
::.::::.: . .. : .::.:.:: ::.:: ::::::: :.:::.: ..:.::
NP_001 ILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPST---S
.: : ::.::::: :: ... : . . :.::: .:: :..::.... .: :
NP_001 LSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKTGMFEGCTTGCPS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 LGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAV
: : :::. .:......:: :. ....:. . :. :.:.
NP_001 LLPILEPKYAVEKIVEAILQEKMYLYMPKLLYFMMFLKRLHLAQDGSECLTEAMWDRAKD
250 260 270 280 290 300
300
pF1KB5 IGYKMKAQ
NP_001 PGQAIRNSGLRSHYSLSL
310
>>NP_004744 (OMIM: 612830) short-chain dehydrogenase/red (302 aa)
initn: 464 init1: 393 opt: 597 Z-score: 774.8 bits: 151.4 E(85289): 2e-36
Smith-Waterman score: 597; 35.9% identity (70.8% similar) in 284 aa overlap (5-283:6-287)
10 20 30 40 50
pF1KB5 MKFLLDILLLLPL-LIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAK
: :...:: .: ... : : .: . .... : :::::.:.:::: : :::.
NP_004 MVWKRLGALVMFPLQMIYLVVKAAVGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LKS-KLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSIL
. :.::: ... :.::. . . .:.. : :. : .:::..:..:: :. ..::..::
NP_004 RGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITIL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 VNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHV
::::.::. ..:. ..: . :. ..:.:..::::::::: : . ..:::: . :. .
NP_004 VNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 SVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPST---SLG
..: . ::.:: .: .: ..:: :. :. ::..: . : ..: .... . .:
NP_004 AIPGAIDYCTSKASAFAFMESLT--LGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLF
190 200 210 220 230
240 250 260 270 280 290
pF1KB5 PTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIG
: :.:: :. : .... .: ....: .. :. :. :::. : ...
NP_004 PPLKPETVARRTVEAVQLNQALLLLPWTMHALVILKSILPQAALEEIHKFSGTYTCMNTF
240 250 260 270 280 290
300
pF1KB5 YKMKAQ
NP_004 KGRT
300
>>NP_742034 (OMIM: 607599) retinol dehydrogenase 10 [Hom (341 aa)
initn: 744 init1: 464 opt: 572 Z-score: 741.8 bits: 145.5 E(85289): 1.4e-34
Smith-Waterman score: 693; 43.1% identity (66.0% similar) in 288 aa overlap (24-281:24-309)
10 20 30 40 50 60
pF1KB5 MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLK
. .. ..:::.:.. :::::: :.::: : :::. .
NP_742 MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRR
10 20 30 40 50 60
70 80 90
pF1KB5 SKLVLWDINKHGLEETAAKCK----------------GLGA---------KVHTFVVDCS
. ::::::: .. ::::. . : : .: :.. : .
NP_742 ALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 NREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAF
.::..: .:..:. :.:.::.:::::::: :. : ::.:. :: :::::::::
NP_742 KRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB5 LPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTC
::.: . ::::::::::. : :. . ::.:::..::::..:. :: : . :.:::
NP_742 LPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 LCPNFVNTGF-----IKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLE
.:: .:.::. :.. . : :.:. :.. :..:::.: :: : . ..: ..
NP_742 VCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMK
250 260 270 280 290 300
280 290 300
pF1KB5 RILPERFLAVLKRKISVKFDAVIGYKMKAQ
::: : ::.
NP_742 SILP--FEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI
310 320 330 340
>>NP_001311299 (OMIM: 612830) short-chain dehydrogenase/ (217 aa)
initn: 414 init1: 351 opt: 443 Z-score: 577.7 bits: 114.5 E(85289): 1.9e-25
Smith-Waterman score: 443; 35.3% identity (71.6% similar) in 204 aa overlap (83-283:1-202)
60 70 80 90 100 110
pF1KB5 AYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIG
.:.. : :. : .:::..:..:: :. ..:
NP_001 MGTECHYFICDVGNREEVYQTAKAVREKVG
10 20 30
120 130 140 150 160 170
pF1KB5 DVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVAS
:..::::::.::. ..:. ..: . :. ..:.:..::::::::: : . ..:::: . :
NP_001 DITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNS
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB5 AAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPST-
. . ..: . ::.:: .: .: ..:: :. :. ::..: . : ..: .... .
NP_001 VLALSAIPGAIDYCTSKASAFAFMESLT--LGLLDCPGVSATTVLPFHTSTEMFQGMRVR
100 110 120 130 140
240 250 260 270 280
pF1KB5 --SLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKF
.: : :.:: :. : .... .: ....: .. :. :. :::. : ...
NP_001 FPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALVILKSILPQAALEEIHKFSGTYT
150 160 170 180 190 200
290 300
pF1KB5 DAVIGYKMKAQ
NP_001 CMNTFKGRT
210
>>XP_016858298 (OMIM: 612830) PREDICTED: short-chain deh (217 aa)
initn: 414 init1: 351 opt: 443 Z-score: 577.7 bits: 114.5 E(85289): 1.9e-25
Smith-Waterman score: 443; 35.3% identity (71.6% similar) in 204 aa overlap (83-283:1-202)
60 70 80 90 100 110
pF1KB5 AYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIG
.:.. : :. : .:::..:..:: :. ..:
XP_016 MGTECHYFICDVGNREEVYQTAKAVREKVG
10 20 30
120 130 140 150 160 170
pF1KB5 DVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVAS
:..::::::.::. ..:. ..: . :. ..:.:..::::::::: : . ..:::: . :
XP_016 DITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNS
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB5 AAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPST-
. . ..: . ::.:: .: .: ..:: :. :. ::..: . : ..: .... .
XP_016 VLALSAIPGAIDYCTSKASAFAFMESLT--LGLLDCPGVSATTVLPFHTSTEMFQGMRVR
100 110 120 130 140
240 250 260 270 280
pF1KB5 --SLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKF
.: : :.:: :. : .... .: ....: .. :. :. :::. : ...
XP_016 FPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALVILKSILPQAALEEIHKFSGTYT
150 160 170 180 190 200
290 300
pF1KB5 DAVIGYKMKAQ
XP_016 CMNTFKGRT
210
300 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:26:19 2016 done: Sat Nov 5 12:26:20 2016
Total Scan time: 6.240 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]