Result of FASTA (omim) for
pF1KB5285
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5285, 727 aa
1>>>pF1KB5285 727 - 727 aa - 727 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.2087+/-0.000428; mu= 5.1535+/- 0.027
mean_var=333.1114+/-68.994, 0's: 0 Z-trim(121.5): 1864 B-trim: 28 in 1/55
Lambda= 0.070272
statistics sampled from 36049 (38204) to 36049 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.448), width: 16
Scan time: 11.210
The best scores are: opt bits E(85289)
XP_016878357 (OMIM: 604167,615502) PREDICTED: tran ( 727) 5025 523.8 9.7e-148
NP_006556 (OMIM: 604167,615502) transcriptional re ( 727) 5025 523.8 9.7e-148
XP_005255832 (OMIM: 604167,615502) PREDICTED: tran ( 725) 5001 521.3 5.2e-147
XP_016878358 (OMIM: 604167,615502) PREDICTED: tran ( 725) 5001 521.3 5.2e-147
NP_001177951 (OMIM: 604167,615502) transcriptional ( 399) 2819 299.8 1.4e-80
NP_001255970 (OMIM: 607022) transcriptional repres ( 663) 1894 206.3 3.3e-52
NP_542185 (OMIM: 607022) transcriptional repressor ( 663) 1894 206.3 3.3e-52
NP_001255969 (OMIM: 607022) transcriptional repres ( 663) 1894 206.3 3.3e-52
NP_001255972 (OMIM: 607022) transcriptional repres ( 700) 1894 206.3 3.4e-52
NP_001255971 (OMIM: 607022) transcriptional repres ( 662) 1887 205.6 5.3e-52
NP_001255973 (OMIM: 607022) transcriptional repres ( 665) 1883 205.2 7.1e-52
NP_001255978 (OMIM: 607022) transcriptional repres ( 460) 1850 201.6 5.7e-51
NP_001255976 (OMIM: 607022) transcriptional repres ( 573) 1819 198.6 5.8e-50
NP_001255974 (OMIM: 607022) transcriptional repres ( 627) 1819 198.7 6.1e-50
NP_001255979 (OMIM: 607022) transcriptional repres ( 422) 1786 195.1 4.8e-49
NP_001255983 (OMIM: 607022) transcriptional repres ( 403) 1766 193.1 1.9e-48
NP_001255984 (OMIM: 607022) transcriptional repres ( 299) 1702 186.4 1.4e-46
NP_001255975 (OMIM: 607022) transcriptional repres ( 613) 983 113.9 2e-24
XP_011515622 (OMIM: 194526) PREDICTED: zinc finger ( 499) 813 96.6 2.6e-19
XP_016869365 (OMIM: 194526) PREDICTED: zinc finger ( 499) 813 96.6 2.6e-19
XP_011524764 (OMIM: 616798) PREDICTED: zinc finger ( 771) 817 97.2 2.7e-19
NP_001273699 (OMIM: 194526) zinc finger protein 34 ( 520) 813 96.6 2.7e-19
XP_011515620 (OMIM: 194526) PREDICTED: zinc finger ( 539) 813 96.6 2.8e-19
XP_011515617 (OMIM: 194526) PREDICTED: zinc finger ( 539) 813 96.6 2.8e-19
XP_011515618 (OMIM: 194526) PREDICTED: zinc finger ( 539) 813 96.6 2.8e-19
XP_016869364 (OMIM: 194526) PREDICTED: zinc finger ( 539) 813 96.6 2.8e-19
NP_001273698 (OMIM: 194526) zinc finger protein 34 ( 539) 813 96.6 2.8e-19
XP_011524765 (OMIM: 616798) PREDICTED: zinc finger ( 859) 817 97.2 2.8e-19
XP_016869362 (OMIM: 194526) PREDICTED: zinc finger ( 560) 813 96.6 2.9e-19
XP_016869363 (OMIM: 194526) PREDICTED: zinc finger ( 560) 813 96.6 2.9e-19
NP_085057 (OMIM: 194526) zinc finger protein 34 is ( 560) 813 96.6 2.9e-19
XP_011515616 (OMIM: 194526) PREDICTED: zinc finger ( 560) 813 96.6 2.9e-19
XP_016869361 (OMIM: 194526) PREDICTED: zinc finger ( 560) 813 96.6 2.9e-19
NP_065879 (OMIM: 616798) zinc finger protein 28 ho ( 868) 817 97.2 2.9e-19
NP_001278562 (OMIM: 606740) zinc finger protein 18 ( 665) 809 96.3 4.2e-19
NP_001265438 (OMIM: 606740) zinc finger protein 18 ( 665) 809 96.3 4.2e-19
NP_001265437 (OMIM: 606740) zinc finger protein 18 ( 667) 809 96.3 4.2e-19
NP_001275688 (OMIM: 606740) zinc finger protein 18 ( 691) 809 96.3 4.3e-19
NP_037388 (OMIM: 606740) zinc finger protein 180 i ( 692) 809 96.3 4.3e-19
XP_011525582 (OMIM: 606740) PREDICTED: zinc finger ( 734) 809 96.4 4.5e-19
NP_060770 (OMIM: 194558) zinc finger protein 83 [H ( 516) 798 95.1 7.8e-19
NP_001264881 (OMIM: 194558) zinc finger protein 83 ( 516) 798 95.1 7.8e-19
NP_001264878 (OMIM: 194558) zinc finger protein 83 ( 516) 798 95.1 7.8e-19
NP_001099021 (OMIM: 194558) zinc finger protein 83 ( 516) 798 95.1 7.8e-19
NP_001099019 (OMIM: 194558) zinc finger protein 83 ( 516) 798 95.1 7.8e-19
NP_001099020 (OMIM: 194558) zinc finger protein 83 ( 516) 798 95.1 7.8e-19
NP_001099022 (OMIM: 194558) zinc finger protein 83 ( 516) 798 95.1 7.8e-19
NP_001264874 (OMIM: 194558) zinc finger protein 83 ( 516) 798 95.1 7.8e-19
NP_001264877 (OMIM: 194558) zinc finger protein 83 ( 516) 798 95.1 7.8e-19
NP_001264880 (OMIM: 194558) zinc finger protein 83 ( 516) 798 95.1 7.8e-19
>>XP_016878357 (OMIM: 604167,615502) PREDICTED: transcri (727 aa)
initn: 5025 init1: 5025 opt: 5025 Z-score: 2773.4 bits: 523.8 E(85289): 9.7e-148
Smith-Waterman score: 5025; 100.0% identity (100.0% similar) in 727 aa overlap (1-727:1-727)
10 20 30 40 50 60
pF1KB5 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 NAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 ALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 HFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 KMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGRTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGRTN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 QPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEM
670 680 690 700 710 720
pF1KB5 ILSMMDR
:::::::
XP_016 ILSMMDR
>>NP_006556 (OMIM: 604167,615502) transcriptional repres (727 aa)
initn: 5025 init1: 5025 opt: 5025 Z-score: 2773.4 bits: 523.8 E(85289): 9.7e-148
Smith-Waterman score: 5025; 100.0% identity (100.0% similar) in 727 aa overlap (1-727:1-727)
10 20 30 40 50 60
pF1KB5 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 NAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 ALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 HFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 KMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGRTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGRTN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 QPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEM
670 680 690 700 710 720
pF1KB5 ILSMMDR
:::::::
NP_006 ILSMMDR
>>XP_005255832 (OMIM: 604167,615502) PREDICTED: transcri (725 aa)
initn: 5002 init1: 4647 opt: 5001 Z-score: 2760.3 bits: 521.3 E(85289): 5.2e-147
Smith-Waterman score: 5001; 99.7% identity (99.7% similar) in 727 aa overlap (1-727:1-725)
10 20 30 40 50 60
pF1KB5 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 NAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 ALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 HFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 KMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGRTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGRTN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 QPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEM
::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPKQNQP--IIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEM
670 680 690 700 710
pF1KB5 ILSMMDR
:::::::
XP_005 ILSMMDR
720
>>XP_016878358 (OMIM: 604167,615502) PREDICTED: transcri (725 aa)
initn: 5002 init1: 4647 opt: 5001 Z-score: 2760.3 bits: 521.3 E(85289): 5.2e-147
Smith-Waterman score: 5001; 99.7% identity (99.7% similar) in 727 aa overlap (1-727:1-725)
10 20 30 40 50 60
pF1KB5 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 NAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 ALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 HFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 KMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGRTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGRTN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 QPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEM
::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPKQNQP--IIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEM
670 680 690 700 710
pF1KB5 ILSMMDR
:::::::
XP_016 ILSMMDR
720
>>NP_001177951 (OMIM: 604167,615502) transcriptional rep (399 aa)
initn: 2819 init1: 2819 opt: 2819 Z-score: 1567.8 bits: 299.8 E(85289): 1.4e-80
Smith-Waterman score: 2819; 100.0% identity (100.0% similar) in 399 aa overlap (329-727:1-399)
300 310 320 330 340 350
pF1KB5 CGRAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDY
::::::::::::::::::::::::::::::
NP_001 MAFVTSGELVRHRRYKHTHEKPFKCSMCDY
10 20 30
360 370 380 390 400 410
pF1KB5 ASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQ
40 50 60 70 80 90
420 430 440 450 460 470
pF1KB5 SGTMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGTMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHE
100 110 120 130 140 150
480 490 500 510 520 530
pF1KB5 RYALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLL
160 170 180 190 200 210
540 550 560 570 580 590
pF1KB5 DMHFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DMHFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGR
220 230 240 250 260 270
600 610 620 630 640 650
pF1KB5 KRKMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGR
280 290 300 310 320 330
660 670 680 690 700 710
pF1KB5 TNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTP
340 350 360 370 380 390
720
pF1KB5 EMILSMMDR
:::::::::
NP_001 EMILSMMDR
>>NP_001255970 (OMIM: 607022) transcriptional repressor (663 aa)
initn: 1806 init1: 1806 opt: 1894 Z-score: 1058.4 bits: 206.3 E(85289): 3.3e-52
Smith-Waterman score: 1894; 47.4% identity (70.1% similar) in 639 aa overlap (13-631:10-618)
10 20 30 40 50 60
pF1KB5 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
:: : : :: . . .. .:.:. ... . .:. . .:..
NP_001 MAATEISVLSEQFTKIKELELMPEKGLKEEEKDGVCREKDHRSPSELEAERTSGA--
10 20 30 40 50
70 80 90 100 110
pF1KB5 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQL-----
.. ..:. ..:.. .:: :. . :.:::.:.. . ... ...:
NP_001 -----FQDSVLEEEVELV---LAPSEES---EKYILTLQTVHFTSEAVELQDMSLLSIQQ
60 70 80 90 100
120 130 140 150 160
pF1KB5 -------VQVPVPVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVK
:: : : . . . :: ...: . .: . . : :. .:..
NP_001 QEGVQVVVQQPGPGLLWLEEGPRQSLQQCVAISIQQELYSPQEMEVLQFHALEENVMVAS
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB5 VGANGEVETLEQGELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTE-----EGKD---
.. : : : :. . .:. : :..::. .: ..: : .:
NP_001 EDSKLAVSLAETTGLIKLEEEQ-EKN---QLLAERTKE----QLFFVETMSGDERSDEIV
170 180 190 200 210
230 240 250 260 270 280
pF1KB5 VDVSVYDFEEEQQEGLLSEVNAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSN
. :: . ::.... ....:::. : : . : ::.: ::.:..: .: : :.
NP_001 LTVSNSNVEEQEDQPTAGQADAEKA----KSTKNQR-KTKGAKGTFHCDVCMFTSSRMSS
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB5 LDRHMKSHTDERPHKCHLCGRAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRH
..::::.::.:.:: :::: ..::::::::::.::::::::.:: ::.::::::::::::
NP_001 FNRHMKTHTSEKPHLCHLCLKTFRTVTLLRNHVNTHTGTRPYKCNDCNMAFVTSGELVRH
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB5 RRYKHTHEKPFKCSMCDYASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRT
:::::::::::::::: :::::.::::::.::::::::::: :::::::::::::::::
NP_001 RRYKHTHEKPFKCSMCKYASVEASKLKRHVRSHTGERPFQCCQCSYASRDTYKLKRHMRT
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB5 HSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQH
:::::::::.:::.:::::::::.:::::: ::: :..:::: :.::::::: ::.:. :
NP_001 HSGEKPYECHICHTRFTQSGTMKIHILQKHGENVPKYQCPHCATIIARKSDLRVHMRNLH
400 410 420 430 440 450
470 480 490 500 510 520
pF1KB5 SYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGE
.: :::::.::::::::::::::.::::::::: .:.:::.::::: : ::::::
NP_001 AYSAAELKCRYCSAVFHERYALIQHQKTHKNEKRFKCKHCSYACKQERHMTAHIRTHTGE
460 470 480 490 500 510
530 540 550 560 570 580
pF1KB5 KPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGP
::..: :.: :::::::. ::..::: ::.:... :::::: :.: .. ::...:..
NP_001 KPFTCLSCNKCFRQKQLLNAHFRKYHDANFIPTVYKCSKCGKGFSRWINLHRHSEKCGSG
520 530 540 550 560 570
590 600 610 620 630 640
pF1KB5 DGVEGENGGETKKSKRGRKRKMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQP
.. . .: :..: ::::. :: .. ...: . . .: :.:
NP_001 EAKSAASG----KGRRTRKRKQTILKEATKGQKEAAKGWKEAANGDEAAAEEASTTKGEQ
580 590 600 610 620
650 660 670 680 690 700
pF1KB5 VTPAPPPAKKRRGRPPGRTNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGE
NP_001 FPGEMFPVACRETTARVKEEVDEGVTCEMLLNTMDK
630 640 650 660
>>NP_542185 (OMIM: 607022) transcriptional repressor CTC (663 aa)
initn: 1806 init1: 1806 opt: 1894 Z-score: 1058.4 bits: 206.3 E(85289): 3.3e-52
Smith-Waterman score: 1894; 47.4% identity (70.1% similar) in 639 aa overlap (13-631:10-618)
10 20 30 40 50 60
pF1KB5 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
:: : : :: . . .. .:.:. ... . .:. . .:..
NP_542 MAATEISVLSEQFTKIKELELMPEKGLKEEEKDGVCREKDHRSPSELEAERTSGA--
10 20 30 40 50
70 80 90 100 110
pF1KB5 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQL-----
.. ..:. ..:.. .:: :. . :.:::.:.. . ... ...:
NP_542 -----FQDSVLEEEVELV---LAPSEES---EKYILTLQTVHFTSEAVELQDMSLLSIQQ
60 70 80 90 100
120 130 140 150 160
pF1KB5 -------VQVPVPVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVK
:: : : . . . :: ...: . .: . . : :. .:..
NP_542 QEGVQVVVQQPGPGLLWLEEGPRQSLQQCVAISIQQELYSPQEMEVLQFHALEENVMVAS
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB5 VGANGEVETLEQGELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTE-----EGKD---
.. : : : :. . .:. : :..::. .: ..: : .:
NP_542 EDSKLAVSLAETTGLIKLEEEQ-EKN---QLLAERTKE----QLFFVETMSGDERSDEIV
170 180 190 200 210
230 240 250 260 270 280
pF1KB5 VDVSVYDFEEEQQEGLLSEVNAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSN
. :: . ::.... ....:::. : : . : ::.: ::.:..: .: : :.
NP_542 LTVSNSNVEEQEDQPTAGQADAEKA----KSTKNQR-KTKGAKGTFHCDVCMFTSSRMSS
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB5 LDRHMKSHTDERPHKCHLCGRAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRH
..::::.::.:.:: :::: ..::::::::::.::::::::.:: ::.::::::::::::
NP_542 FNRHMKTHTSEKPHLCHLCLKTFRTVTLLRNHVNTHTGTRPYKCNDCNMAFVTSGELVRH
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB5 RRYKHTHEKPFKCSMCDYASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRT
:::::::::::::::: :::::.::::::.::::::::::: :::::::::::::::::
NP_542 RRYKHTHEKPFKCSMCKYASVEASKLKRHVRSHTGERPFQCCQCSYASRDTYKLKRHMRT
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB5 HSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQH
:::::::::.:::.:::::::::.:::::: ::: :..:::: :.::::::: ::.:. :
NP_542 HSGEKPYECHICHTRFTQSGTMKIHILQKHGENVPKYQCPHCATIIARKSDLRVHMRNLH
400 410 420 430 440 450
470 480 490 500 510 520
pF1KB5 SYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGE
.: :::::.::::::::::::::.::::::::: .:.:::.::::: : ::::::
NP_542 AYSAAELKCRYCSAVFHERYALIQHQKTHKNEKRFKCKHCSYACKQERHMTAHIRTHTGE
460 470 480 490 500 510
530 540 550 560 570 580
pF1KB5 KPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGP
::..: :.: :::::::. ::..::: ::.:... :::::: :.: .. ::...:..
NP_542 KPFTCLSCNKCFRQKQLLNAHFRKYHDANFIPTVYKCSKCGKGFSRWINLHRHSEKCGSG
520 530 540 550 560 570
590 600 610 620 630 640
pF1KB5 DGVEGENGGETKKSKRGRKRKMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQP
.. . .: :..: ::::. :: .. ...: . . .: :.:
NP_542 EAKSAASG----KGRRTRKRKQTILKEATKGQKEAAKGWKEAANGDEAAAEEASTTKGEQ
580 590 600 610 620
650 660 670 680 690 700
pF1KB5 VTPAPPPAKKRRGRPPGRTNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGE
NP_542 FPGEMFPVACRETTARVKEEVDEGVTCEMLLNTMDK
630 640 650 660
>>NP_001255969 (OMIM: 607022) transcriptional repressor (663 aa)
initn: 1806 init1: 1806 opt: 1894 Z-score: 1058.4 bits: 206.3 E(85289): 3.3e-52
Smith-Waterman score: 1894; 47.4% identity (70.1% similar) in 639 aa overlap (13-631:10-618)
10 20 30 40 50 60
pF1KB5 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
:: : : :: . . .. .:.:. ... . .:. . .:..
NP_001 MAATEISVLSEQFTKIKELELMPEKGLKEEEKDGVCREKDHRSPSELEAERTSGA--
10 20 30 40 50
70 80 90 100 110
pF1KB5 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQL-----
.. ..:. ..:.. .:: :. . :.:::.:.. . ... ...:
NP_001 -----FQDSVLEEEVELV---LAPSEES---EKYILTLQTVHFTSEAVELQDMSLLSIQQ
60 70 80 90 100
120 130 140 150 160
pF1KB5 -------VQVPVPVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVK
:: : : . . . :: ...: . .: . . : :. .:..
NP_001 QEGVQVVVQQPGPGLLWLEEGPRQSLQQCVAISIQQELYSPQEMEVLQFHALEENVMVAS
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB5 VGANGEVETLEQGELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTE-----EGKD---
.. : : : :. . .:. : :..::. .: ..: : .:
NP_001 EDSKLAVSLAETTGLIKLEEEQ-EKN---QLLAERTKE----QLFFVETMSGDERSDEIV
170 180 190 200 210
230 240 250 260 270 280
pF1KB5 VDVSVYDFEEEQQEGLLSEVNAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSN
. :: . ::.... ....:::. : : . : ::.: ::.:..: .: : :.
NP_001 LTVSNSNVEEQEDQPTAGQADAEKA----KSTKNQR-KTKGAKGTFHCDVCMFTSSRMSS
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB5 LDRHMKSHTDERPHKCHLCGRAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRH
..::::.::.:.:: :::: ..::::::::::.::::::::.:: ::.::::::::::::
NP_001 FNRHMKTHTSEKPHLCHLCLKTFRTVTLLRNHVNTHTGTRPYKCNDCNMAFVTSGELVRH
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB5 RRYKHTHEKPFKCSMCDYASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRT
:::::::::::::::: :::::.::::::.::::::::::: :::::::::::::::::
NP_001 RRYKHTHEKPFKCSMCKYASVEASKLKRHVRSHTGERPFQCCQCSYASRDTYKLKRHMRT
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB5 HSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQH
:::::::::.:::.:::::::::.:::::: ::: :..:::: :.::::::: ::.:. :
NP_001 HSGEKPYECHICHTRFTQSGTMKIHILQKHGENVPKYQCPHCATIIARKSDLRVHMRNLH
400 410 420 430 440 450
470 480 490 500 510 520
pF1KB5 SYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGE
.: :::::.::::::::::::::.::::::::: .:.:::.::::: : ::::::
NP_001 AYSAAELKCRYCSAVFHERYALIQHQKTHKNEKRFKCKHCSYACKQERHMTAHIRTHTGE
460 470 480 490 500 510
530 540 550 560 570 580
pF1KB5 KPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGP
::..: :.: :::::::. ::..::: ::.:... :::::: :.: .. ::...:..
NP_001 KPFTCLSCNKCFRQKQLLNAHFRKYHDANFIPTVYKCSKCGKGFSRWINLHRHSEKCGSG
520 530 540 550 560 570
590 600 610 620 630 640
pF1KB5 DGVEGENGGETKKSKRGRKRKMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQP
.. . .: :..: ::::. :: .. ...: . . .: :.:
NP_001 EAKSAASG----KGRRTRKRKQTILKEATKGQKEAAKGWKEAANGDEAAAEEASTTKGEQ
580 590 600 610 620
650 660 670 680 690 700
pF1KB5 VTPAPPPAKKRRGRPPGRTNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGE
NP_001 FPGEMFPVACRETTARVKEEVDEGVTCEMLLNTMDK
630 640 650 660
>>NP_001255972 (OMIM: 607022) transcriptional repressor (700 aa)
initn: 1806 init1: 1806 opt: 1894 Z-score: 1058.1 bits: 206.3 E(85289): 3.4e-52
Smith-Waterman score: 1894; 47.4% identity (70.1% similar) in 639 aa overlap (13-631:10-618)
10 20 30 40 50 60
pF1KB5 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
:: : : :: . . .. .:.:. ... . .:. . .:..
NP_001 MAATEISVLSEQFTKIKELELMPEKGLKEEEKDGVCREKDHRSPSELEAERTSGA--
10 20 30 40 50
70 80 90 100 110
pF1KB5 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQL-----
.. ..:. ..:.. .:: :. . :.:::.:.. . ... ...:
NP_001 -----FQDSVLEEEVELV---LAPSEES---EKYILTLQTVHFTSEAVELQDMSLLSIQQ
60 70 80 90 100
120 130 140 150 160
pF1KB5 -------VQVPVPVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVK
:: : : . . . :: ...: . .: . . : :. .:..
NP_001 QEGVQVVVQQPGPGLLWLEEGPRQSLQQCVAISIQQELYSPQEMEVLQFHALEENVMVAS
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB5 VGANGEVETLEQGELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTE-----EGKD---
.. : : : :. . .:. : :..::. .: ..: : .:
NP_001 EDSKLAVSLAETTGLIKLEEEQ-EKN---QLLAERTKE----QLFFVETMSGDERSDEIV
170 180 190 200 210
230 240 250 260 270 280
pF1KB5 VDVSVYDFEEEQQEGLLSEVNAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSN
. :: . ::.... ....:::. : : . : ::.: ::.:..: .: : :.
NP_001 LTVSNSNVEEQEDQPTAGQADAEKA----KSTKNQR-KTKGAKGTFHCDVCMFTSSRMSS
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB5 LDRHMKSHTDERPHKCHLCGRAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRH
..::::.::.:.:: :::: ..::::::::::.::::::::.:: ::.::::::::::::
NP_001 FNRHMKTHTSEKPHLCHLCLKTFRTVTLLRNHVNTHTGTRPYKCNDCNMAFVTSGELVRH
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB5 RRYKHTHEKPFKCSMCDYASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRT
:::::::::::::::: :::::.::::::.::::::::::: :::::::::::::::::
NP_001 RRYKHTHEKPFKCSMCKYASVEASKLKRHVRSHTGERPFQCCQCSYASRDTYKLKRHMRT
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB5 HSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQH
:::::::::.:::.:::::::::.:::::: ::: :..:::: :.::::::: ::.:. :
NP_001 HSGEKPYECHICHTRFTQSGTMKIHILQKHGENVPKYQCPHCATIIARKSDLRVHMRNLH
400 410 420 430 440 450
470 480 490 500 510 520
pF1KB5 SYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGE
.: :::::.::::::::::::::.::::::::: .:.:::.::::: : ::::::
NP_001 AYSAAELKCRYCSAVFHERYALIQHQKTHKNEKRFKCKHCSYACKQERHMTAHIRTHTGE
460 470 480 490 500 510
530 540 550 560 570 580
pF1KB5 KPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGP
::..: :.: :::::::. ::..::: ::.:... :::::: :.: .. ::...:..
NP_001 KPFTCLSCNKCFRQKQLLNAHFRKYHDANFIPTVYKCSKCGKGFSRWINLHRHSEKCGSG
520 530 540 550 560 570
590 600 610 620 630 640
pF1KB5 DGVEGENGGETKKSKRGRKRKMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQP
.. . .: :..: ::::. :: .. ...: . . .: :.:
NP_001 EAKSAASG----KGRRTRKRKQTILKEATKGQKEAAKGWKEAANGDEAAAEEASTTKGEQ
580 590 600 610 620
650 660 670 680 690 700
pF1KB5 VTPAPPPAKKRRGRPPGRTNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGE
NP_001 FPGEMFPVACRETTARVKEEVDEGVTCEMLLNTMDNSAGCTGRMMLVSAWLLGRPQETYN
630 640 650 660 670 680
>>NP_001255971 (OMIM: 607022) transcriptional repressor (662 aa)
initn: 1806 init1: 1806 opt: 1887 Z-score: 1054.6 bits: 205.6 E(85289): 5.3e-52
Smith-Waterman score: 1887; 46.4% identity (68.4% similar) in 673 aa overlap (13-659:10-652)
10 20 30 40 50 60
pF1KB5 MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM
:: : : :: . . .. .:.:. ... . .:. . .:..
NP_001 MAATEISVLSEQFTKIKELELMPEKGLKEEEKDGVCREKDHRSPSELEAERTSGA--
10 20 30 40 50
70 80 90 100 110
pF1KB5 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQL-----
.. ..:. ..:.. .:: :. . :.:::.:.. . ... ...:
NP_001 -----FQDSVLEEEVELV---LAPSEES---EKYILTLQTVHFTSEAVELQDMSLLSIQQ
60 70 80 90 100
120 130 140 150 160
pF1KB5 -------VQVPVPVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVK
:: : : . . . :: ...: . .: . . : :. .:..
NP_001 QEGVQVVVQQPGPGLLWLEEGPRQSLQQCVAISIQQELYSPQEMEVLQFHALEENVMVAS
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB5 VGANGEVETLEQGELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTE-----EGKD---
.. : : : :. . .:. : :..::. .: ..: : .:
NP_001 EDSKLAVSLAETTGLIKLEEEQ-EKN---QLLAERTKE----QLFFVETMSGDERSDEIV
170 180 190 200 210
230 240 250 260 270 280
pF1KB5 VDVSVYDFEEEQQEGLLSEVNAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSN
. :: . ::.... ....:::. : : . : ::.: ::.:..: .: : :.
NP_001 LTVSNSNVEEQEDQPTAGQADAEKA----KSTKNQR-KTKGAKGTFHCDVCMFTSSRMSS
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB5 LDRHMKSHTDERPHKCHLCGRAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRH
..::::.::.:.:: :::: ..::::::::::.::::::::.:: ::.::::::::::::
NP_001 FNRHMKTHTSEKPHLCHLCLKTFRTVTLLRNHVNTHTGTRPYKCNDCNMAFVTSGELVRH
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB5 RRYKHTHEKPFKCSMCDYASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRT
:::::::::::::::: :::::.::::::.::::::::::: :::::::::::::::::
NP_001 RRYKHTHEKPFKCSMCKYASVEASKLKRHVRSHTGERPFQCCQCSYASRDTYKLKRHMRT
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB5 HSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQH
:::::::::.:::.:::::::::.:::::: ::: :..:::: :.::::::: ::.:. :
NP_001 HSGEKPYECHICHTRFTQSGTMKIHILQKHGENVPKYQCPHCATIIARKSDLRVHMRNLH
400 410 420 430 440 450
470 480 490 500 510 520
pF1KB5 SYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGE
.: :::::.::::::::::::::.::::::::: .:.:::.::::: : ::::::
NP_001 AYSAAELKCRYCSAVFHERYALIQHQKTHKNEKRFKCKHCSYACKQERHMTAHIRTHTGE
460 470 480 490 500 510
530 540 550 560 570 580
pF1KB5 KPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGP
::..: :.: :::::::. ::..::: ::.:... :::::: :.: .. ::...:..
NP_001 KPFTCLSCNKCFRQKQLLNAHFRKYHDANFIPTVYKCSKCGKGFSRWINLHRHSEKCGSG
520 530 540 550 560 570
590 600 610 620 630
pF1KB5 DGVEGENGGETKKSKRGRKRKMRSKKEDSSDSENA-----EPDLDDNEDEEEPAVEIEPE
.. . .: :..: ::::. :: .. ...: : : :: ... :
NP_001 EAKSAASG----KGRRTRKRKQTILKEATKGQKEAAKGWKEAANGDAAAEEASTTKGEQF
580 590 600 610 620
640 650 660 670 680 690
pF1KB5 P-EPQPVTPAPPPAKKRRGRPPGRTNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDA
: : ::. :. .. : :
NP_001 PGEMFPVACRETTARVKEEVDEGVTCEMLLNTMDK
630 640 650 660
727 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 22:26:36 2016 done: Thu Nov 3 22:26:38 2016
Total Scan time: 11.210 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]