FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5282, 225 aa
  1>>>pF1KB5282 225 - 225 aa - 225 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2179+/-0.000437; mu= 14.2211+/- 0.027
 mean_var=61.3889+/-12.468, 0's: 0 Z-trim(109.4): 14  B-trim: 41 in 2/48
 Lambda= 0.163693
 statistics sampled from 17614 (17619) to 17614 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.574), E-opt: 0.2 (0.207), width:  16
 Scan time:  5.250

The best scores are:                                      opt bits E(85289)
NP_064585 (OMIM: 610751) phosphoribosyltransferase ( 225) 1497 362.2 3.9e-100
NP_001269715 (OMIM: 610751) phosphoribosyltransfer ( 190) 1212 294.9 6.2e-80
NP_000185 (OMIM: 300322,300323,308000) hypoxanthin ( 218) 1002 245.3 5.9e-65


>>NP_064585 (OMIM: 610751) phosphoribosyltransferase dom  (225 aa)
 initn: 1497 init1: 1497 opt: 1497  Z-score: 1918.7  bits: 362.2 E(85289): 3.9e-100
Smith-Waterman score: 1497; 99.6% identity (99.6% similar) in 225 aa overlap (1-225:1-225)

               10        20        30        40        50        60
pF1KB5 MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDWEYVLIPHGIIVDRIERLAKDI
       :::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_064 MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 MKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 MQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDG
              130       140       150       160       170       180

              190       200       210       220     
pF1KB5 FRPDYAGFEIPNLFVVGYALDYNEYFRDLNHICVINEHGKEKYRV
       :::::::::::::::::::::::::::::::::::::::::::::
NP_064 FRPDYAGFEIPNLFVVGYALDYNEYFRDLNHICVINEHGKEKYRV
              190       200       210       220     

>>NP_001269715 (OMIM: 610751) phosphoribosyltransferase   (190 aa)
 initn: 1212 init1: 1212 opt: 1212  Z-score: 1556.1  bits: 294.9 E(85289): 6.2e-80
Smith-Waterman score: 1212; 99.5% identity (99.5% similar) in 184 aa overlap (1-184:1-184)

               10        20        30        40        50        60
pF1KB5 MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDWEYVLIPHGIIVDRIERLAKDI
       :::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_001 MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 MKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 MQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDG
              130       140       150       160       170       180

              190       200       210       220     
pF1KB5 FRPDYAGFEIPNLFVVGYALDYNEYFRDLNHICVINEHGKEKYRV
       ::::                                         
NP_001 FRPDSHMRHQ                                   
              190                                   

>>NP_000185 (OMIM: 300322,300323,308000) hypoxanthine-gu  (218 aa)
 initn: 1018 init1: 1002 opt: 1002  Z-score: 1287.1  bits: 245.3 E(85289): 5.9e-65
Smith-Waterman score: 1002; 67.8% identity (87.7% similar) in 211 aa overlap (14-224:7-217)

               10        20        30        40        50        60
pF1KB5 MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDWEYVLIPHGIIVDRIERLAKDI
                    :::: :: :::::.::  :.::  : : :.::::.:.:: ::::.:.
NP_000        MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDV
                      10        20        30        40        50   

               70        80        90       100       110       120
pF1KB5 MKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGE
       ::..:   :..:::::::::: :::....: ..::::: . : ::::::::: :::: :.
NP_000 MKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGD
            60        70        80        90       100       110   

              130       140       150       160       170       180
pF1KB5 MQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDG
       ...:::::::::.:::::::::.. ::.::..::: ...:.:.:.:::::::::: :: :
NP_000 IKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVG
           120       130       140       150       160       170   

              190       200       210       220     
pF1KB5 FRPDYAGFEIPNLFVVGYALDYNEYFRDLNHICVINEHGKEKYRV
       ..::..:::::. ::::::::::::::::::.:::.: :: ::. 
NP_000 YKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
           180       190       200       210        




225 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:31:50 2016 done: Fri Nov  4 03:31:51 2016
 Total Scan time:  5.250 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]