Result of FASTA (omim) for
pF1KB5278
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5278, 375 aa
1>>>pF1KB5278 375 - 375 aa - 375 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2401+/-0.000409; mu= 16.2078+/- 0.025
mean_var=57.4141+/-11.855, 0's: 0 Z-trim(110.7): 178 B-trim: 321 in 1/50
Lambda= 0.169264
statistics sampled from 18868 (19090) to 18868 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.224), width: 16
Scan time: 7.720
The best scores are: opt bits E(85289)
XP_016857602 (OMIM: 606494) PREDICTED: CMP-N-acety ( 375) 2495 617.8 1.2e-176
NP_006270 (OMIM: 606494) CMP-N-acetylneuraminate-b ( 375) 2495 617.8 1.2e-176
XP_006710888 (OMIM: 606494) PREDICTED: CMP-N-acety ( 434) 2316 574.1 2e-163
NP_777624 (OMIM: 606494) CMP-N-acetylneuraminate-b ( 390) 2228 552.6 5.5e-157
NP_777629 (OMIM: 606494) CMP-N-acetylneuraminate-b ( 359) 2136 530.1 2.9e-150
XP_011540279 (OMIM: 606494) PREDICTED: CMP-N-acety ( 449) 2049 508.9 8.9e-144
NP_777631 (OMIM: 606494) CMP-N-acetylneuraminate-b ( 413) 2043 507.5 2.3e-143
NP_777628 (OMIM: 606494) CMP-N-acetylneuraminate-b ( 429) 2043 507.5 2.4e-143
NP_777623 (OMIM: 606494) CMP-N-acetylneuraminate-b ( 444) 2043 507.5 2.4e-143
XP_006710890 (OMIM: 606494) PREDICTED: CMP-N-acety ( 418) 1957 486.5 4.9e-137
XP_011540282 (OMIM: 606494) PREDICTED: CMP-N-acety ( 379) 1865 464.0 2.6e-130
XP_016857600 (OMIM: 606494) PREDICTED: CMP-N-acety ( 392) 1864 463.7 3.1e-130
XP_016857601 (OMIM: 606494) PREDICTED: CMP-N-acety ( 392) 1864 463.7 3.1e-130
XP_011540278 (OMIM: 606494) PREDICTED: CMP-N-acety ( 472) 1864 463.8 3.7e-130
XP_011540276 (OMIM: 606494) PREDICTED: CMP-N-acety ( 488) 1864 463.8 3.8e-130
XP_011540275 (OMIM: 606494) PREDICTED: CMP-N-acety ( 502) 1864 463.8 3.9e-130
XP_016857598 (OMIM: 606494) PREDICTED: CMP-N-acety ( 503) 1864 463.8 3.9e-130
XP_016857608 (OMIM: 606494) PREDICTED: CMP-N-acety ( 282) 1841 458.1 1.2e-128
NP_001257389 (OMIM: 606494) CMP-N-acetylneuraminat ( 344) 1834 456.4 4.5e-128
XP_016857610 (OMIM: 606494) PREDICTED: CMP-N-acety ( 268) 1790 445.6 6.2e-125
XP_016857609 (OMIM: 606494) PREDICTED: CMP-N-acety ( 268) 1790 445.6 6.2e-125
XP_011540285 (OMIM: 606494) PREDICTED: CMP-N-acety ( 340) 1702 424.2 2.2e-118
XP_016857605 (OMIM: 606494) PREDICTED: CMP-N-acety ( 340) 1702 424.2 2.2e-118
XP_006710891 (OMIM: 606494) PREDICTED: CMP-N-acety ( 341) 1662 414.4 2e-115
XP_016857603 (OMIM: 606494) PREDICTED: CMP-N-acety ( 341) 1662 414.4 2e-115
XP_016857604 (OMIM: 606494) PREDICTED: CMP-N-acety ( 341) 1662 414.4 2e-115
NP_777626 (OMIM: 606494) CMP-N-acetylneuraminate-b ( 277) 1658 413.4 3.2e-115
NP_001257388 (OMIM: 606494) CMP-N-acetylneuraminat ( 345) 1658 413.4 3.9e-115
XP_011540290 (OMIM: 606494) PREDICTED: CMP-N-acety ( 327) 1611 401.9 1.1e-111
XP_011540289 (OMIM: 606494) PREDICTED: CMP-N-acety ( 327) 1611 401.9 1.1e-111
XP_016857607 (OMIM: 606494) PREDICTED: CMP-N-acety ( 292) 1391 348.2 1.4e-95
NP_001257390 (OMIM: 606494) CMP-N-acetylneuraminat ( 261) 1299 325.7 7.5e-89
XP_016857606 (OMIM: 606494) PREDICTED: CMP-N-acety ( 331) 1206 303.0 6.4e-82
XP_011540283 (OMIM: 606494) PREDICTED: CMP-N-acety ( 346) 1206 303.0 6.6e-82
XP_011540288 (OMIM: 606494) PREDICTED: CMP-N-acety ( 331) 1204 302.5 8.9e-82
XP_011540286 (OMIM: 606494) PREDICTED: CMP-N-acety ( 331) 1204 302.5 8.9e-82
XP_011540287 (OMIM: 606494) PREDICTED: CMP-N-acety ( 331) 1204 302.5 8.9e-82
XP_016857599 (OMIM: 606494) PREDICTED: CMP-N-acety ( 456) 1205 302.8 1e-81
NP_001257394 (OMIM: 606494) CMP-N-acetylneuraminat ( 185) 1121 282.2 6.7e-76
NP_001257392 (OMIM: 606494) CMP-N-acetylneuraminat ( 201) 1117 281.2 1.4e-75
NP_001257391 (OMIM: 606494) CMP-N-acetylneuraminat ( 230) 997 251.9 1.1e-66
XP_016857611 (OMIM: 606494) PREDICTED: CMP-N-acety ( 221) 911 230.9 2.2e-60
NP_777627 (OMIM: 606494) CMP-N-acetylneuraminate-b ( 155) 887 225.0 9.1e-59
NP_001257393 (OMIM: 606494) CMP-N-acetylneuraminat ( 186) 870 220.9 1.9e-57
XP_016860689 (OMIM: 604402,609056) PREDICTED: lact ( 390) 789 201.2 3.3e-51
XP_016860690 (OMIM: 604402,609056) PREDICTED: lact ( 390) 789 201.2 3.3e-51
XP_016860688 (OMIM: 604402,609056) PREDICTED: lact ( 390) 789 201.2 3.3e-51
NP_001035902 (OMIM: 604402,609056) lactosylceramid ( 395) 789 201.2 3.3e-51
NP_003887 (OMIM: 604402,609056) lactosylceramide a ( 418) 789 201.2 3.5e-51
XP_016860701 (OMIM: 604402,609056) PREDICTED: lact ( 290) 753 192.4 1.1e-48
>>XP_016857602 (OMIM: 606494) PREDICTED: CMP-N-acetylneu (375 aa)
initn: 2495 init1: 2495 opt: 2495 Z-score: 3292.1 bits: 617.8 E(85289): 1.2e-176
Smith-Waterman score: 2495; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KB5 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR
310 320 330 340 350 360
370
pF1KB5 KLVKARVITDLSSGI
:::::::::::::::
XP_016 KLVKARVITDLSSGI
370
>>NP_006270 (OMIM: 606494) CMP-N-acetylneuraminate-beta- (375 aa)
initn: 2495 init1: 2495 opt: 2495 Z-score: 3292.1 bits: 617.8 E(85289): 1.2e-176
Smith-Waterman score: 2495; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KB5 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR
310 320 330 340 350 360
370
pF1KB5 KLVKARVITDLSSGI
:::::::::::::::
NP_006 KLVKARVITDLSSGI
370
>>XP_006710888 (OMIM: 606494) PREDICTED: CMP-N-acetylneu (434 aa)
initn: 2316 init1: 2316 opt: 2316 Z-score: 3054.8 bits: 574.1 E(85289): 2e-163
Smith-Waterman score: 2316; 99.1% identity (99.1% similar) in 350 aa overlap (1-350:1-350)
10 20 30 40 50 60
pF1KB5 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR
:::::::::::::::::::::::::::::::::::::::::::::: :
XP_006 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKEPRPHVENLNPSELR
310 320 330 340 350 360
370
pF1KB5 KLVKARVITDLSSGI
XP_006 LPHFCFDHQPSTDPSLKPGNLGPVLQQLLCCYIWVMGGCWREPPICADSCFFLDAQYPAR
370 380 390 400 410 420
>>NP_777624 (OMIM: 606494) CMP-N-acetylneuraminate-beta- (390 aa)
initn: 2228 init1: 2228 opt: 2228 Z-score: 2939.4 bits: 552.6 E(85289): 5.5e-157
Smith-Waterman score: 2450; 95.9% identity (96.2% similar) in 390 aa overlap (1-375:1-390)
10 20 30 40
pF1KB5 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS---------------NSVVLS
::::::::::::::::::::::::::::::::::::::: .:::::
NP_777 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK
310 320 330 340 350 360
350 360 370
pF1KB5 ESWTHNIQREKEFLRKLVKARVITDLSSGI
::::::::::::::::::::::::::::::
NP_777 ESWTHNIQREKEFLRKLVKARVITDLSSGI
370 380 390
>>NP_777629 (OMIM: 606494) CMP-N-acetylneuraminate-beta- (359 aa)
initn: 2136 init1: 2136 opt: 2136 Z-score: 2818.6 bits: 530.1 E(85289): 2.9e-150
Smith-Waterman score: 2352; 95.5% identity (95.7% similar) in 375 aa overlap (1-375:1-359)
10 20 30 40 50 60
pF1KB5 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
::::::::::::::::::::::::::::::::::::::: .::::
NP_777 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS----------------KYDRL
10 20 30 40
70 80 90 100 110 120
pF1KB5 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR
290 300 310 320 330 340
370
pF1KB5 KLVKARVITDLSSGI
:::::::::::::::
NP_777 KLVKARVITDLSSGI
350
>>XP_011540279 (OMIM: 606494) PREDICTED: CMP-N-acetylneu (449 aa)
initn: 2049 init1: 2049 opt: 2049 Z-score: 2702.2 bits: 508.9 E(85289): 8.9e-144
Smith-Waterman score: 2271; 94.8% identity (95.1% similar) in 365 aa overlap (1-350:1-365)
10 20 30 40
pF1KB5 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS---------------NSVVLS
::::::::::::::::::::::::::::::::::::::: .:::::
XP_011 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK
310 320 330 340 350 360
350 360 370
pF1KB5 ESWTHNIQREKEFLRKLVKARVITDLSSGI
: :
XP_011 EPRPHVENLNPSELRLPHFCFDHQPSTDPSLKPGNLGPVLQQLLCCYIWVMGGCWREPPI
370 380 390 400 410 420
>>NP_777631 (OMIM: 606494) CMP-N-acetylneuraminate-beta- (413 aa)
initn: 2293 init1: 2040 opt: 2043 Z-score: 2694.9 bits: 507.5 E(85289): 2.3e-143
Smith-Waterman score: 2196; 83.2% identity (83.5% similar) in 423 aa overlap (7-375:7-413)
10 20 30 40 50 60
pF1KB5 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
::::::::::::::::::::::::::::::::: .::::
NP_777 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS----------------KYDRL
10 20 30 40
70
pF1KB5 GFLLNLDSKL--------------------------------------------------
::::::::::
NP_777 GFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDTAFALGFL
50 60 70 80 90 100
80 90 100 110 120
pF1KB5 ----PAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 KLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP
110 120 130 140 150 160
130 140 150 160 170 180
pF1KB5 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR
170 180 190 200 210 220
190 200 210 220 230 240
pF1KB5 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE
230 240 250 260 270 280
250 260 270 280 290 300
pF1KB5 RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA
290 300 310 320 330 340
310 320 330 340 350 360
pF1KB5 VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR
350 360 370 380 390 400
370
pF1KB5 VITDLSSGI
:::::::::
NP_777 VITDLSSGI
410
>>NP_777628 (OMIM: 606494) CMP-N-acetylneuraminate-beta- (429 aa)
initn: 2481 init1: 2040 opt: 2043 Z-score: 2694.6 bits: 507.5 E(85289): 2.4e-143
Smith-Waterman score: 2238; 86.7% identity (86.7% similar) in 407 aa overlap (23-375:23-429)
10 20 30 40 50 60
pF1KB5 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
::::::::::::::::::::::::::::::::::::::
NP_777 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
10 20 30 40 50 60
70
pF1KB5 GFLLNLDSKL--------------------------------------------------
::::::::::
NP_777 GFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDTAFALGFL
70 80 90 100 110 120
80 90 100 110 120
pF1KB5 ----PAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 KLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB5 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB5 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB5 RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB5 VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR
370 380 390 400 410 420
370
pF1KB5 VITDLSSGI
:::::::::
NP_777 VITDLSSGI
>>NP_777623 (OMIM: 606494) CMP-N-acetylneuraminate-beta- (444 aa)
initn: 2290 init1: 2040 opt: 2043 Z-score: 2694.4 bits: 507.5 E(85289): 2.4e-143
Smith-Waterman score: 2110; 85.7% identity (86.2% similar) in 391 aa overlap (39-375:54-444)
10 20 30 40 50 60
pF1KB5 NLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRLGFLLNLDS
..::::::::::::::::::::::::::::
NP_777 YYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLSFDSAGQTLGSEYDRLGFLLNLDS
30 40 50 60 70 80
70
pF1KB5 KL------------------------------------------------------PAEL
:: ::::
NP_777 KLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDTAFALGFLKLPRPAEL
90 100 110 120 130 140
80 90 100 110 120 130
pF1KB5 ATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 ATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDN
150 160 170 180 190 200
140 150 160 170 180 190
pF1KB5 LIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 LIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG
210 220 230 240 250 260
200 210 220 230 240 250
pF1KB5 FEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 FEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGF
270 280 290 300 310 320
260 270 280 290 300 310
pF1KB5 WKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 WKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGC
330 340 350 360 370 380
320 330 340 350 360 370
pF1KB5 DEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 DEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSG
390 400 410 420 430 440
pF1KB5 I
:
NP_777 I
>--
initn: 266 init1: 264 opt: 264 Z-score: 346.5 bits: 73.0 E(85289): 1.5e-12
Smith-Waterman score: 264; 97.5% identity (100.0% similar) in 40 aa overlap (1-40:1-40)
10 20 30 40 50 60
pF1KB5 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
:::::::::::::::::::::::::::::::::::::::.
NP_777 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
NP_777 FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI
70 80 90 100 110 120
>>XP_006710890 (OMIM: 606494) PREDICTED: CMP-N-acetylneu (418 aa)
initn: 1957 init1: 1957 opt: 1957 Z-score: 2581.3 bits: 486.5 E(85289): 4.9e-137
Smith-Waterman score: 2173; 94.3% identity (94.6% similar) in 350 aa overlap (1-350:1-334)
10 20 30 40 50 60
pF1KB5 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL
::::::::::::::::::::::::::::::::::::::: .::::
XP_006 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS----------------KYDRL
10 20 30 40
70 80 90 100 110 120
pF1KB5 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR
:::::::::::::::::::::::::::::::::::::::::::::: :
XP_006 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKEPRPHVENLNPSELR
290 300 310 320 330 340
370
pF1KB5 KLVKARVITDLSSGI
XP_006 LPHFCFDHQPSTDPSLKPGNLGPVLQQLLCCYIWVMGGCWREPPICADSCFFLDAQYPAR
350 360 370 380 390 400
375 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:23:31 2016 done: Sat Nov 5 12:23:33 2016
Total Scan time: 7.720 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]