Result of FASTA (omim) for
pF1KB5235
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5235, 509 aa
1>>>pF1KB5235 509 - 509 aa - 509 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5967+/-0.000431; mu= 18.0044+/- 0.027
mean_var=88.2507+/-17.525, 0's: 0 Z-trim(111.2): 27 B-trim: 175 in 2/53
Lambda= 0.136526
statistics sampled from 19709 (19736) to 19709 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.59), E-opt: 0.2 (0.231), width: 16
Scan time: 8.820
The best scores are: opt bits E(85289)
NP_002100 (OMIM: 142810,614504,616625) histidine-- ( 509) 3303 661.1 2.2e-189
NP_001276023 (OMIM: 142810,614504,616625) histidin ( 480) 3128 626.6 4.9e-179
NP_001244969 (OMIM: 142810,614504,616625) histidin ( 469) 2680 538.3 1.8e-152
NP_036340 (OMIM: 600783,614926) probable histidine ( 506) 2466 496.2 9.2e-140
XP_011535921 (OMIM: 600783,614926) PREDICTED: prob ( 512) 2465 496.0 1.1e-139
NP_001265660 (OMIM: 600783,614926) probable histid ( 481) 2407 484.6 2.8e-136
XP_016864777 (OMIM: 600783,614926) PREDICTED: prob ( 436) 2361 475.5 1.4e-133
XP_016864778 (OMIM: 600783,614926) PREDICTED: prob ( 436) 2361 475.5 1.4e-133
NP_001244971 (OMIM: 142810,614504,616625) histidin ( 449) 2187 441.2 2.9e-123
NP_001244970 (OMIM: 142810,614504,616625) histidin ( 489) 2183 440.5 5.4e-123
NP_001276022 (OMIM: 142810,614504,616625) histidin ( 395) 2181 440.0 6e-123
NP_001276021 (OMIM: 142810,614504,616625) histidin ( 435) 2177 439.3 1.1e-122
NP_001265661 (OMIM: 600783,614926) probable histid ( 362) 1816 368.1 2.5e-101
XP_016864780 (OMIM: 600783,614926) PREDICTED: prob ( 286) 1527 311.1 2.8e-84
XP_016864781 (OMIM: 600783,614926) PREDICTED: prob ( 286) 1527 311.1 2.8e-84
XP_016864779 (OMIM: 600783,614926) PREDICTED: prob ( 286) 1527 311.1 2.8e-84
XP_016864776 (OMIM: 600783,614926) PREDICTED: prob ( 473) 1396 285.4 2.4e-76
XP_011535922 (OMIM: 600783,614926) PREDICTED: prob ( 479) 1396 285.5 2.4e-76
XP_011519901 (OMIM: 234810,609280) PREDICTED: eIF- (1611) 525 114.3 2.7e-24
XP_005254449 (OMIM: 234810,609280) PREDICTED: eIF- (1626) 525 114.3 2.7e-24
NP_001013725 (OMIM: 234810,609280) eIF-2-alpha kin (1649) 525 114.3 2.8e-24
XP_016877708 (OMIM: 234810,609280) PREDICTED: eIF- (1554) 219 54.0 3.7e-06
XP_011519902 (OMIM: 234810,609280) PREDICTED: eIF- (1592) 219 54.0 3.7e-06
>>NP_002100 (OMIM: 142810,614504,616625) histidine--tRNA (509 aa)
initn: 3303 init1: 3303 opt: 3303 Z-score: 3521.1 bits: 661.1 E(85289): 2.2e-189
Smith-Waterman score: 3303; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
430 440 450 460 470 480
490 500
pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC
:::::::::::::::::::::::::::::
NP_002 VTSREEVDVRREDLVEEIKRRTGQPLCIC
490 500
>>NP_001276023 (OMIM: 142810,614504,616625) histidine--t (480 aa)
initn: 3128 init1: 3128 opt: 3128 Z-score: 3335.2 bits: 626.6 E(85289): 4.9e-179
Smith-Waterman score: 3128; 99.8% identity (100.0% similar) in 480 aa overlap (30-509:1-480)
10 20 30 40 50 60
pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
.::::::::::::::::::::::::::::::
NP_001 MIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
10 20 30
70 80 90 100 110 120
pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
400 410 420 430 440 450
490 500
pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC
:::::::::::::::::::::::::::::
NP_001 VTSREEVDVRREDLVEEIKRRTGQPLCIC
460 470 480
>>NP_001244969 (OMIM: 142810,614504,616625) histidine--t (469 aa)
initn: 2677 init1: 2677 opt: 2680 Z-score: 2858.4 bits: 538.3 E(85289): 1.8e-152
Smith-Waterman score: 2943; 92.1% identity (92.1% similar) in 509 aa overlap (1-509:1-469)
10 20 30 40 50 60
pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ
::::::::::::::::::::
NP_001 ----------------------------------------ETLMGKYGEDSKLIYDLKDQ
70 80
130 140 150 160 170 180
pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
390 400 410 420 430 440
490 500
pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC
:::::::::::::::::::::::::::::
NP_001 VTSREEVDVRREDLVEEIKRRTGQPLCIC
450 460
>>NP_036340 (OMIM: 600783,614926) probable histidine--tR (506 aa)
initn: 2489 init1: 2460 opt: 2466 Z-score: 2630.2 bits: 496.2 E(85289): 9.2e-140
Smith-Waterman score: 2466; 76.3% identity (93.9% similar) in 473 aa overlap (32-504:34-505)
10 20 30 40 50 60
pF1KB5 AERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKG
. .::. . : .:: . : .:..:::::
NP_036 LGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAV-LTSQLKAHQEKPNFIIKTPKG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 TRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQG
::: ::..:.::::..:..: :::::::. .:::.::::::: :::::: :.:::::::
NP_036 TRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKDQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGN
::::::::::::::::::::::. ..::::..::.::..:....:::::: ::::::::.
NP_036 GELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIAGQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKL
:::::::::::::::::::.::.::::.:::::::.:::::.::: .::::.::::.:::
NP_036 FDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSIDKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGD
::..:..:..::: .:::::::::::::::: :::::::::..:::.:::::::::::::
NP_036 DKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGG
::::::::::::: :::::::::::::::::::::::::::::.:::::::.::::::::
NP_036 LKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 RYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLL
:::::::::::::.::::::::::::::: :::::... ::.:::::::.::. ::..:
NP_036 RYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSV
.:::::..::::.:::::.:::.:::::.::.::: .:::::.::::::::.::::.:::
NP_036 QERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSV
430 440 450 460 470 480
490 500
pF1KB5 TSREEVDVRREDLVEEIKRRTGQPLCIC
.::::: ..::..: ::..: ..
NP_036 ASREEVAIKRENFVAEIQKRLSES
490 500
>>XP_011535921 (OMIM: 600783,614926) PREDICTED: probable (512 aa)
initn: 2489 init1: 2460 opt: 2465 Z-score: 2629.0 bits: 496.0 E(85289): 1.1e-139
Smith-Waterman score: 2465; 77.4% identity (94.4% similar) in 464 aa overlap (41-504:48-511)
20 30 40 50 60 70
pF1KB5 VKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQM
: .:: . : .:..:::::::: ::..:
XP_011 QLLRPPCASCTGAVRCQSQGEESLQVAEAVLTSQLKAHQEKPNFIIKTPKGTRDLSPQHM
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB5 AVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYD
.::::..:..: :::::::. .:::.::::::: :::::: :.::::::::::::::::
XP_011 VVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKDQGGELLSLRYD
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB5 LTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAE
:::::::::::::. ..::::..::.::..:....:::::: ::::::::.:::::::::
XP_011 LTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIAGQFDPMIPDAE
140 150 160 170 180 190
200 210 220 230 240 250
pF1KB5 CLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVK
::::::::::.::.::::.:::::::.:::::.::: .::::.::::.:::::..:..:.
XP_011 CLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSIDKLDKMAWKDVR
200 210 220 230 240 250
260 270 280 290 300 310
pF1KB5 NEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLT
.::: .:::::::::::::::: :::::::::..:::.::::::::::::::::::::::
XP_011 HEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGLGDLKLLFEYLT
260 270 280 290 300 310
320 330 340 350 360 370
pF1KB5 LFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMF
:::: :::::::::::::::::::::::::::::.:::::::.:::::::::::::::::
XP_011 LFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGGRYDGLVGMF
320 330 340 350 360 370
380 390 400 410 420 430
pF1KB5 DPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSE
::::.::::::::::::::: :::::... ::.:::::::.::. ::..:.:::::..:
XP_011 DPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIAE
380 390 400 410 420 430
440 450 460 470 480 490
pF1KB5 LWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVR
:::.:::::.:::.:::::.::.::: .:::::.::::::::.::::.:::.::::: ..
XP_011 LWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIK
440 450 460 470 480 490
500
pF1KB5 REDLVEEIKRRTGQPLCIC
::..: ::..: ..
XP_011 RENFVAEIQKRLSES
500 510
>>NP_001265660 (OMIM: 600783,614926) probable histidine- (481 aa)
initn: 2434 init1: 2405 opt: 2407 Z-score: 2567.7 bits: 484.6 E(85289): 2.8e-136
Smith-Waterman score: 2407; 78.7% identity (95.5% similar) in 445 aa overlap (60-504:36-480)
30 40 50 60 70 80
pF1KB5 LIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGA
.:::: ::..:.::::..:..: :::::::
NP_001 LLPRRAWASLLSQLLRPPCASCTGAVRCQSQGTRDLSPQHMVVREKILDLVISCFKRHGA
10 20 30 40 50 60
90 100 110 120 130 140
pF1KB5 EVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKR
. .:::.::::::: :::::: :.:::::::::::::::::::::::::::::. ..::
NP_001 KGMDTPAFELKETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKR
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB5 YHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLV
::..::.::..:....:::::: ::::::::.:::::::::::::::::::.::.::::.
NP_001 YHVGKVWRRESPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLI
130 140 150 160 170 180
210 220 230 240 250 260
pF1KB5 KVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGD
:::::::.:::::.::: .::::.::::.:::::..:..:..::: .:::::::::::::
NP_001 KVNDRRIVDGMFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGD
190 200 210 220 230 240
270 280 290 300 310 320
pF1KB5 YVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLD
::: :::::::::..:::.:::::::::::::::::::::::::: ::::::::::::::
NP_001 YVQCHGGVSLVEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLD
250 260 270 280 290 300
330 340 350 360 370 380
pF1KB5 YYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERI
:::::::::::::::.:::::::.:::::::::::::::::::::.::::::::::::::
NP_001 YYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERI
310 320 330 340 350 360
390 400 410 420 430 440
pF1KB5 FSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLL
: :::::... ::.:::::::.::. ::..:.:::::..::::.:::::.:::.:::::
NP_001 FYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLL
370 380 390 400 410 420
450 460 470 480 490 500
pF1KB5 NQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC
.::.::: .:::::.::::::::.::::.:::.::::: ..::..: ::..: ..
NP_001 TQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
430 440 450 460 470 480
>>XP_016864777 (OMIM: 600783,614926) PREDICTED: probable (436 aa)
initn: 2383 init1: 2354 opt: 2361 Z-score: 2519.3 bits: 475.5 E(85289): 1.4e-133
Smith-Waterman score: 2361; 79.1% identity (95.6% similar) in 435 aa overlap (70-504:1-435)
40 50 60 70 80 90
pF1KB5 KLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFEL
:.::::..:..: :::::::. .:::.:::
XP_016 MVVREKILDLVISCFKRHGAKGMDTPAFEL
10 20 30
100 110 120 130 140 150
pF1KB5 KETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRD
:::: :::::: :.:::::::::::::::::::::::::::::. ..::::..::.::.
XP_016 KETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRE
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 NPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDG
.:....:::::: ::::::::.:::::::::::::::::::.::.::::.:::::::.::
XP_016 SPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDG
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 MFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSL
:::.::: .::::.::::.:::::..:..:..::: .:::::::::::::::: ::::::
XP_016 MFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 VEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAV
:::..:::.:::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 VEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAV
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 LLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEA
:::::.:::::::.:::::::::::::::::::::.::::::::::::::: :::::...
XP_016 LLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKT
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB5 LEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAG
::.:::::::.::. ::..:.:::::..::::.:::::.:::.:::::.::.::: .:
XP_016 KGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTG
340 350 360 370 380 390
460 470 480 490 500
pF1KB5 IPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC
::::.::::::::.::::.:::.::::: ..::..: ::..: ..
XP_016 IPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
400 410 420 430
>>XP_016864778 (OMIM: 600783,614926) PREDICTED: probable (436 aa)
initn: 2383 init1: 2354 opt: 2361 Z-score: 2519.3 bits: 475.5 E(85289): 1.4e-133
Smith-Waterman score: 2361; 79.1% identity (95.6% similar) in 435 aa overlap (70-504:1-435)
40 50 60 70 80 90
pF1KB5 KLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFEL
:.::::..:..: :::::::. .:::.:::
XP_016 MVVREKILDLVISCFKRHGAKGMDTPAFEL
10 20 30
100 110 120 130 140 150
pF1KB5 KETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRD
:::: :::::: :.:::::::::::::::::::::::::::::. ..::::..::.::.
XP_016 KETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRE
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 NPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDG
.:....:::::: ::::::::.:::::::::::::::::::.::.::::.:::::::.::
XP_016 SPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDG
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 MFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSL
:::.::: .::::.::::.:::::..:..:..::: .:::::::::::::::: ::::::
XP_016 MFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 VEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAV
:::..:::.:::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 VEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAV
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 LLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEA
:::::.:::::::.:::::::::::::::::::::.::::::::::::::: :::::...
XP_016 LLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKT
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB5 LEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAG
::.:::::::.::. ::..:.:::::..::::.:::::.:::.:::::.::.::: .:
XP_016 KGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTG
340 350 360 370 380 390
460 470 480 490 500
pF1KB5 IPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC
::::.::::::::.::::.:::.::::: ..::..: ::..: ..
XP_016 IPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
400 410 420 430
>>NP_001244971 (OMIM: 142810,614504,616625) histidine--t (449 aa)
initn: 2526 init1: 2176 opt: 2187 Z-score: 2333.9 bits: 441.2 E(85289): 2.9e-123
Smith-Waterman score: 2745; 88.2% identity (88.2% similar) in 509 aa overlap (1-509:1-449)
10 20 30 40 50 60
pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ
::::::::::::::::::::
NP_001 ----------------------------------------ETLMGKYGEDSKLIYDLKDQ
70 80
130 140 150 160 170 180
pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG
:::::::::::::::::::::::::::::::::: ::::::
NP_001 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAK--------------------DFDIAG
90 100 110 120
190 200 210 220 230 240
pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
370 380 390 400 410 420
490 500
pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC
:::::::::::::::::::::::::::::
NP_001 VTSREEVDVRREDLVEEIKRRTGQPLCIC
430 440
>>NP_001244970 (OMIM: 142810,614504,616625) histidine--t (489 aa)
initn: 3141 init1: 2176 opt: 2183 Z-score: 2329.1 bits: 440.5 E(85289): 5.4e-123
Smith-Waterman score: 3105; 96.1% identity (96.1% similar) in 509 aa overlap (1-509:1-489)
10 20 30 40 50 60
pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG
:::::::::::::::::::::::::::::::::: ::::::
NP_001 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAK--------------------DFDIAG
130 140 150 160
190 200 210 220 230 240
pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
410 420 430 440 450 460
490 500
pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC
:::::::::::::::::::::::::::::
NP_001 VTSREEVDVRREDLVEEIKRRTGQPLCIC
470 480
509 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:15:21 2016 done: Fri Nov 4 22:15:23 2016
Total Scan time: 8.820 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]