Result of FASTA (omim) for
pF1KB5155
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5155, 511 aa
1>>>pF1KB5155 511 - 511 aa - 511 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7277+/-0.000389; mu= 21.7719+/- 0.024
mean_var=65.0068+/-13.000, 0's: 0 Z-trim(110.6): 68 B-trim: 1074 in 1/55
Lambda= 0.159072
statistics sampled from 18970 (19039) to 18970 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.223), width: 16
Scan time: 7.390
The best scores are: opt bits E(85289)
NP_001188306 (OMIM: 107323,266100) alpha-aminoadip ( 511) 3407 791.1 0
NP_001173 (OMIM: 107323,266100) alpha-aminoadipic ( 539) 3407 791.1 0
XP_016864982 (OMIM: 107323,266100) PREDICTED: alph ( 404) 2695 627.6 2e-179
XP_011541719 (OMIM: 107323,266100) PREDICTED: alph ( 404) 2695 627.6 2e-179
NP_001189333 (OMIM: 107323,266100) alpha-aminoadip ( 475) 2029 474.8 2.4e-133
NP_001193826 (OMIM: 603687) retinal dehydrogenase ( 497) 764 184.6 6e-46
NP_003879 (OMIM: 603687) retinal dehydrogenase 2 i ( 518) 758 183.2 1.6e-45
XP_011516104 (OMIM: 100670) PREDICTED: aldehyde de ( 517) 752 181.8 4.2e-45
NP_000683 (OMIM: 100670) aldehyde dehydrogenase X, ( 517) 752 181.8 4.2e-45
XP_011536288 (OMIM: 613584) PREDICTED: mitochondri ( 777) 740 179.2 3.8e-44
XP_016874378 (OMIM: 613584) PREDICTED: mitochondri ( 777) 740 179.2 3.8e-44
NP_001029345 (OMIM: 613584) mitochondrial 10-formy ( 923) 740 179.3 4.4e-44
NP_000684 (OMIM: 600463,615113) aldehyde dehydroge ( 512) 720 174.5 6.8e-43
NP_000680 (OMIM: 100640) retinal dehydrogenase 1 [ ( 501) 719 174.2 7.8e-43
NP_000681 (OMIM: 100650,610251) aldehyde dehydroge ( 517) 706 171.3 6.3e-42
NP_001257294 (OMIM: 600249) cytosolic 10-formyltet ( 801) 697 169.3 3.7e-41
NP_036322 (OMIM: 600249) cytosolic 10-formyltetrah ( 902) 697 169.4 4e-41
XP_006713544 (OMIM: 600249) PREDICTED: cytosolic 1 ( 902) 697 169.4 4e-41
XP_011510657 (OMIM: 600249) PREDICTED: cytosolic 1 ( 902) 697 169.4 4e-41
NP_001257293 (OMIM: 600249) cytosolic 10-formyltet ( 912) 697 169.4 4e-41
NP_000687 (OMIM: 602733) 4-trimethylaminobutyralde ( 518) 670 163.0 1.9e-39
NP_733798 (OMIM: 603687) retinal dehydrogenase 2 i ( 422) 668 162.5 2.3e-39
NP_072090 (OMIM: 606467) aldehyde dehydrogenase fa ( 487) 644 157.0 1.2e-37
NP_001071 (OMIM: 271980,610045) succinate-semialde ( 535) 627 153.1 1.9e-36
XP_011507596 (OMIM: 602733) PREDICTED: 4-trimethyl ( 424) 618 151.0 6.5e-36
NP_001191818 (OMIM: 100650,610251) aldehyde dehydr ( 470) 617 150.8 8.3e-36
XP_016861103 (OMIM: 600249) PREDICTED: cytosolic 1 ( 828) 574 141.1 1.2e-32
XP_016861102 (OMIM: 600249) PREDICTED: cytosolic 1 ( 838) 574 141.1 1.2e-32
NP_005580 (OMIM: 603178,614105) methylmalonate-sem ( 535) 558 137.3 1.1e-31
NP_001280744 (OMIM: 600463,615113) aldehyde dehydr ( 405) 519 128.3 4.4e-29
NP_733797 (OMIM: 603687) retinal dehydrogenase 2 i ( 480) 472 117.5 8.7e-26
NP_001180409 (OMIM: 606467) aldehyde dehydrogenase ( 437) 457 114.1 8.9e-25
NP_001265522 (OMIM: 603178,614105) methylmalonate- ( 522) 456 113.9 1.2e-24
NP_733936 (OMIM: 271980,610045) succinate-semialde ( 548) 453 113.2 2e-24
NP_003739 (OMIM: 239510,606811) delta-1-pyrroline- ( 563) 434 108.9 4.2e-23
NP_733844 (OMIM: 239510,606811) delta-1-pyrroline- ( 563) 434 108.9 4.2e-23
NP_001154976 (OMIM: 239510,606811) delta-1-pyrroli ( 503) 432 108.4 5.3e-23
NP_001265523 (OMIM: 603178,614105) methylmalonate- ( 381) 384 97.2 8.8e-20
XP_016876820 (OMIM: 603178,614105) PREDICTED: meth ( 381) 384 97.2 8.8e-20
NP_001128639 (OMIM: 100660) aldehyde dehydrogenase ( 453) 369 93.9 1.1e-18
NP_001128640 (OMIM: 100660) aldehyde dehydrogenase ( 453) 369 93.9 1.1e-18
NP_000682 (OMIM: 100660) aldehyde dehydrogenase, d ( 453) 369 93.9 1.1e-18
NP_001317079 (OMIM: 100660) aldehyde dehydrogenase ( 380) 358 91.3 5.5e-18
XP_011522033 (OMIM: 100660) PREDICTED: aldehyde de ( 380) 358 91.3 5.5e-18
NP_000373 (OMIM: 270200,609523) fatty aldehyde deh ( 485) 342 87.7 8.4e-17
XP_016879846 (OMIM: 270200,609523) PREDICTED: fatt ( 485) 342 87.7 8.4e-17
XP_016879845 (OMIM: 270200,609523) PREDICTED: fatt ( 485) 342 87.7 8.4e-17
XP_011522035 (OMIM: 270200,609523) PREDICTED: fatt ( 508) 342 87.7 8.7e-17
XP_011522034 (OMIM: 270200,609523) PREDICTED: fatt ( 508) 342 87.7 8.7e-17
NP_001026976 (OMIM: 270200,609523) fatty aldehyde ( 508) 342 87.7 8.7e-17
>>NP_001188306 (OMIM: 107323,266100) alpha-aminoadipic s (511 aa)
initn: 3407 init1: 3407 opt: 3407 Z-score: 4223.8 bits: 791.1 E(85289): 0
Smith-Waterman score: 3407; 100.0% identity (100.0% similar) in 511 aa overlap (1-511:1-511)
10 20 30 40 50 60
pF1KB5 MSTLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 MICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 NEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRES
430 440 450 460 470 480
490 500 510
pF1KB5 GSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
:::::::::::::::::::::::::::::::
NP_001 GSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
490 500 510
>>NP_001173 (OMIM: 107323,266100) alpha-aminoadipic semi (539 aa)
initn: 3407 init1: 3407 opt: 3407 Z-score: 4223.5 bits: 791.1 E(85289): 0
Smith-Waterman score: 3407; 100.0% identity (100.0% similar) in 511 aa overlap (1-511:29-539)
10 20 30
pF1KB5 MSTLLINQPQYAWLKELGLREENEGVYNGSWG
::::::::::::::::::::::::::::::::
NP_001 MWRLPRALCVHAAKTSKLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGSWG
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 GRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 LREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB5 QWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLED
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 NKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGN
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 NAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 NPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHD
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 ASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGI
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB5 VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
490 500 510 520 530
>>XP_016864982 (OMIM: 107323,266100) PREDICTED: alpha-am (404 aa)
initn: 2695 init1: 2695 opt: 2695 Z-score: 3342.1 bits: 627.6 E(85289): 2e-179
Smith-Waterman score: 2695; 100.0% identity (100.0% similar) in 404 aa overlap (108-511:1-404)
80 90 100 110 120 130
pF1KB5 PAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIG
::::::::::::::::::::::::::::::
XP_016 MGKILVEGVGEVQEYVDICDYAVGLSRMIG
10 20 30
140 150 160 170 180 190
pF1KB5 GPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSL
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 ISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLM
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 VQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDE
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 VVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRP
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 GNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLG
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 RIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTIN
340 350 360 370 380 390
500 510
pF1KB5 YSKDLPLAQGIKFQ
::::::::::::::
XP_016 YSKDLPLAQGIKFQ
400
>>XP_011541719 (OMIM: 107323,266100) PREDICTED: alpha-am (404 aa)
initn: 2695 init1: 2695 opt: 2695 Z-score: 3342.1 bits: 627.6 E(85289): 2e-179
Smith-Waterman score: 2695; 100.0% identity (100.0% similar) in 404 aa overlap (108-511:1-404)
80 90 100 110 120 130
pF1KB5 PAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIG
::::::::::::::::::::::::::::::
XP_011 MGKILVEGVGEVQEYVDICDYAVGLSRMIG
10 20 30
140 150 160 170 180 190
pF1KB5 GPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSL
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 ISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLM
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 VQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDE
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 VVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRP
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 GNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLG
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 RIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTIN
340 350 360 370 380 390
500 510
pF1KB5 YSKDLPLAQGIKFQ
::::::::::::::
XP_011 YSKDLPLAQGIKFQ
400
>>NP_001189333 (OMIM: 107323,266100) alpha-aminoadipic s (475 aa)
initn: 2057 init1: 2029 opt: 2029 Z-score: 2515.1 bits: 474.8 E(85289): 2.4e-133
Smith-Waterman score: 2840; 87.5% identity (87.5% similar) in 511 aa overlap (1-511:29-475)
10 20 30
pF1KB5 MSTLLINQPQYAWLKELGLREENEGVYNGSWG
::::::::::::::::::::::::::::::::
NP_001 MWRLPRALCVHAAKTSKLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGSWG
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 GRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 LREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB5 QWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLED
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 NKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGN
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 NAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVG
::::::::::::::::::::::::::::::::::::
NP_001 NAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRL------------------------
310 320 330
340 350 360 370 380 390
pF1KB5 NPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHD
::::::::::::::::::::
NP_001 ----------------------------------------VMDRPGNYVEPTIVTGLGHD
340 350
400 410 420 430 440 450
pF1KB5 ASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGI
360 370 380 390 400 410
460 470 480 490 500 510
pF1KB5 VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
420 430 440 450 460 470
>>NP_001193826 (OMIM: 603687) retinal dehydrogenase 2 is (497 aa)
initn: 708 init1: 365 opt: 764 Z-score: 945.9 bits: 184.6 E(85289): 6e-46
Smith-Waterman score: 764; 30.8% identity (61.4% similar) in 503 aa overlap (7-496:3-490)
10 20 30 40 50
pF1KB5 MSTLLINQPQYAWLKE-LGLREENEGVYNGSWGGR--GEVITTYCPANNEPIARVRQASV
:: . .::: . :. :. : . :.:. .: ::..: . .:..:.
NP_001 MKNQCETVWLKSPIKLKL---IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADK
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 ADYEETVKKAREAWK---IWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVE
:: ...:. :: :.. .: . : .::... ...: ... ::... ::. :: ...
NP_001 ADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 GVG-EVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVY
. ..: . : .: . : : .: . . . . . .:.:. : : .:::. ..
NP_001 AFYVDLQGVIKTFRYYAGWADKIHGMTIPVD-GDYFTFTRHEPIGVCGQIIPWNFPLLMF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 GWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAM
.:. : :. :::. . : : : : .. . .: : . ::.: : : :.:.
NP_001 AWKIAPALCCGNTVVIKPAEQTPLSALYMGALIK---EAGFPPGVINILPGYGPTAGAAI
180 190 200 210 220
240 250 260 270 280
pF1KB5 AKDERVNLLSFTGSTQVGKQVGLMVQERFGRS-----LLELGGNNAIIAFEDADLSLVVP
:. .. ..:::::.::: ..:: ::: :::::.. : : ::::. .:
NP_001 ASHIGIDKIAFTGSTEVGK----LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVE
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB5 SALFAAVGTAGQRCTTARRLFIHESIHDEVVNR-LKKAYAQIRVGNPWDPNVLYGPLHTK
.: .. . :: ::.. :.:..:::..: : : ...: .. ::.:.::.. :: :
NP_001 QAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRV-VGSPFDPTTEQGPQIDK
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB5 QAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYV
. . .: .. . ::. . ::: . : : ..:::. ... : ::. : :.:. .
NP_001 KQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEI
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB5 FKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGA
..::. .::. :. :: ...::.:... . .. . : : .: .. . .
NP_001 LRFKTMDEVIERANNSDFGLVAAVFTNDINKALTV--SSAMQAGTVWINC-YNALNAQSP
410 420 430 440 450 460
470 480 490 500 510
pF1KB5 FGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
::: : .:.::: : . ..: . .: :.
NP_001 FGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS
470 480 490
>>NP_003879 (OMIM: 603687) retinal dehydrogenase 2 isofo (518 aa)
initn: 633 init1: 365 opt: 758 Z-score: 938.2 bits: 183.2 E(85289): 1.6e-45
Smith-Waterman score: 758; 31.0% identity (62.2% similar) in 481 aa overlap (28-496:43-511)
10 20 30 40 50
pF1KB5 MSTLLINQPQYAWLKELGLREENEGVYNGSWGGR--GEVITTYCPANNEPIARVRQA
:. : . :.:. .: ::..: . .:..:
NP_003 KADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEA
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB5 SVADYEETVKKAREAWK---IWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKIL
. :: ...:. :: :.. .: . : .::... ...: ... ::... ::. :: .
NP_003 DKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPF
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB5 VEGVG-EVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVA
... ..: . : .: . : : .: . . . . . .:.:. : : .:::.
NP_003 LQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVD-GDYFTFTRHEPIGVCGQIIPWNFPLL
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB5 VYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGT
...:. : :. :::. . : : : : .. . .: : . ::.: : : :.
NP_003 MFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIK---EAGFPPGVINILPGYGPTAGA
200 210 220 230 240
240 250 260 270 280
pF1KB5 AMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRS-----LLELGGNNAIIAFEDADLSLV
:.:. .. ..:::::.::: ..:: ::: :::::.. : : ::::. .
NP_003 AIASHIGIDKIAFTGSTEVGK----LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 VPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNR-LKKAYAQIRVGNPWDPNVLYGPLH
: .: .. . :: ::.. :.:..:::..: : : ...: .. ::.:.::.. ::
NP_003 VEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRV-VGSPFDPTTEQGPQI
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB5 TKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPIL
:. . .: .. . ::. . ::: . : : ..:::. ... : ::. : :.:.
NP_003 DKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQ
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB5 YVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIG
...::. .::. :. :: ...::.:... . .. . : : .: .. .
NP_003 EILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTV--SSAMQAGTVWINC-YNALNAQ
430 440 450 460 470 480
470 480 490 500 510
pF1KB5 GAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
. ::: : .:.::: : . ..: . .: :.
NP_003 SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS
490 500 510
>>XP_011516104 (OMIM: 100670) PREDICTED: aldehyde dehydr (517 aa)
initn: 639 init1: 377 opt: 752 Z-score: 930.7 bits: 181.8 E(85289): 4.2e-45
Smith-Waterman score: 752; 31.0% identity (61.1% similar) in 481 aa overlap (23-496:37-510)
10 20 30 40 50
pF1KB5 MSTLLINQPQYAWLKELGLREENEGVYNGSWGG--RGEVITTYCPANNEPIA
:. :. : ... : :...: :.
XP_011 PRLLSLQGRTARYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIG
10 20 30 40 50 60
60 70 80 90 100
pF1KB5 RVRQASVADYEETVKKAREAWKI---WADIPAPKRGEIVRQIGDALREKIQVLGSLVSLE
.: ... :: ...:: ::::... : . : .::... ...: ... :.:: .:.
XP_011 HVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 MGKILVEGVG-EVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAF
:: . :. . ...: . . : .: . : .: . . : . . .:::. : : .
XP_011 NGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMD-GQHFCFTRHEPVGVCGQIIPW
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 NFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGG
:::... ::. : :. ::. . : : : : .. ....: : . ::.. .: :
XP_011 NFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIK---EAGFPPGVVNIITGYG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 ADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQER-FGRSLLELGGNNAIIAFEDADLSL
:.:.:. :. ..:::::.::. . . . . : :::::.. :.. :::.
XP_011 PTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEH
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 VVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLH
.: . : . :: : .. : :..:::..: ..: . : .::::.. .. ::
XP_011 AVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQV
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB5 TKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPIL
:. :: .. ..:::. .. ::. . . : ...::. :. : ::. : :.:.
XP_011 DKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQ
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB5 YVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIG
.::::. ::: :... ::....::.:: . . . .. . : : :: . .
XP_011 PLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFT--QALQAGTVWVNT-YNIVTCH
430 440 450 460 470
470 480 490 500 510
pF1KB5 GAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
::: :..:.::: : :. : : . .: ::
XP_011 TPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS
480 490 500 510
>>NP_000683 (OMIM: 100670) aldehyde dehydrogenase X, mit (517 aa)
initn: 639 init1: 377 opt: 752 Z-score: 930.7 bits: 181.8 E(85289): 4.2e-45
Smith-Waterman score: 752; 31.0% identity (61.1% similar) in 481 aa overlap (23-496:37-510)
10 20 30 40 50
pF1KB5 MSTLLINQPQYAWLKELGLREENEGVYNGSWGG--RGEVITTYCPANNEPIA
:. :. : ... : :...: :.
NP_000 PRLLSLQGRTARYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIG
10 20 30 40 50 60
60 70 80 90 100
pF1KB5 RVRQASVADYEETVKKAREAWKI---WADIPAPKRGEIVRQIGDALREKIQVLGSLVSLE
.: ... :: ...:: ::::... : . : .::... ...: ... :.:: .:.
NP_000 HVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 MGKILVEGVG-EVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAF
:: . :. . ...: . . : .: . : .: . . : . . .:::. : : .
NP_000 NGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMD-GQHFCFTRHEPVGVCGQIIPW
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 NFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGG
:::... ::. : :. ::. . : : : : .. ....: : . ::.. .: :
NP_000 NFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIK---EAGFPPGVVNIITGYG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 ADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQER-FGRSLLELGGNNAIIAFEDADLSL
:.:.:. :. ..:::::.::. . . . . : :::::.. :.. :::.
NP_000 PTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEH
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 VVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLH
.: . : . :: : .. : :..:::..: ..: . : .::::.. .. ::
NP_000 AVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQV
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB5 TKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPIL
:. :: .. ..:::. .. ::. . . : ...::. :. : ::. : :.:.
NP_000 DKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQ
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB5 YVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIG
.::::. ::: :... ::....::.:: . . . .. . : : :: . .
NP_000 PLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFT--QALQAGTVWVNT-YNIVTCH
430 440 450 460 470
470 480 490 500 510
pF1KB5 GAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
::: :..:.::: : :. : : . .: ::
NP_000 TPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS
480 490 500 510
>>XP_011536288 (OMIM: 613584) PREDICTED: mitochondrial 1 (777 aa)
initn: 421 init1: 365 opt: 740 Z-score: 913.5 bits: 179.2 E(85289): 3.8e-44
Smith-Waterman score: 740; 28.4% identity (63.2% similar) in 497 aa overlap (14-498:288-777)
10 20 30 40
pF1KB5 MSTLLINQPQYAWLKELGLREENEGVYNGSW--GGRGEVITTY
..:. .. . ::.. . :.. :
XP_011 KFEGFIQKVVRKLRGEDQEVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTI
260 270 280 290 300 310
50 60 70 80 90
pF1KB5 CPANNEPIARVRQASVADYEETVKKAREAWKI--WADIPAPKRGEIVRQIGDALREKIQV
:... : .: ::.:: ...: :..:.. :. . : .::... ...: :.:. .
XP_011 NPTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARERGRLMYRLADLLEENQEE
320 330 340 350 360 370
100 110 120 130 140 150
pF1KB5 LGSLVSLEMGKILVEGVG-EVQEYVDICDYAVGLSRMIGGPILP--SERSGHAL-IEQWN
:... .:. : . . .. .. :. : .: : : .: . : .. : . . .
XP_011 LATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKE
380 390 400 410 420 430
160 170 180 190 200 210
pF1KB5 PVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKL
:.:. .:: .:.:. . .:..: . ::. . : : .: : .. ... .:. .
XP_011 PLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKA----GF
440 450 460 470 480 490
220 230 240 250 260 270
pF1KB5 PGAICSLTCGGADI-GTAMAKDERVNLLSFTGSTQVGKQVGLMVQ-ERFGRSLLELGGNN
: .. .. :.. : : ... . :.::::: .:::. . . :::::..
XP_011 PKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKS
500 510 520 530 540 550
280 290 300 310 320 330
pF1KB5 AIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGN
.: :.: .:. .: .. :. . :. : .: :::..:::::: :.:. . ....:.
XP_011 PLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMKIGD
560 570 580 590 600 610
340 350 360 370 380 390
pF1KB5 PWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDA
: : .. .:: . : . .: : . :::.:.::::. ..::: ..:::. : .
XP_011 PLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRPGFFMEPTVFTDVEDYM
620 630 640 650 660 670
400 410 420 430 440 450
pF1KB5 SIAHTETFAPILYVFKFKNEE--EVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCG
.:. :.:.::. . ::.: . :. : .. ::.:..::.:... . ... : . :
XP_011 YLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAM-YVSEK-LEAG
680 690 700 710 720 730
460 470 480 490 500 510
pF1KB5 IVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
: .: . ..... ::: :..: :.. : .: ..:.. .: :..:
XP_011 TVFINT-YNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY
740 750 760 770
511 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:31:47 2016 done: Sat Nov 5 02:31:48 2016
Total Scan time: 7.390 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]