Result of FASTA (omim) for
pF1KB5081
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5081, 541 aa
1>>>pF1KB5081 541 - 541 aa - 541 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4762+/-0.000366; mu= 17.4289+/- 0.023
mean_var=65.4229+/-13.424, 0's: 0 Z-trim(112.9): 60 B-trim: 0 in 0/52
Lambda= 0.158566
statistics sampled from 21990 (22050) to 21990 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.259), width: 16
Scan time: 10.950
The best scores are: opt bits E(85289)
NP_005619 (OMIM: 109190) neutral amino acid transp ( 541) 3437 795.3 0
XP_005259224 (OMIM: 109190) PREDICTED: neutral ami ( 469) 2932 679.8 5e-195
NP_001138617 (OMIM: 109190) neutral amino acid tra ( 339) 2166 504.5 2.1e-142
NP_001138616 (OMIM: 109190) neutral amino acid tra ( 313) 2008 468.3 1.5e-131
NP_003029 (OMIM: 600229,616657) neutral amino acid ( 532) 1891 441.7 2.7e-123
XP_006712142 (OMIM: 600229,616657) PREDICTED: neut ( 312) 1321 311.2 3.1e-84
XP_011512386 (OMIM: 600111,612656) PREDICTED: exci ( 435) 1019 242.1 2.6e-63
NP_001276868 (OMIM: 600111,612656) excitatory amin ( 496) 1019 242.2 2.9e-63
XP_005248399 (OMIM: 600111,612656) PREDICTED: exci ( 542) 1019 242.2 3.1e-63
NP_004163 (OMIM: 600111,612656) excitatory amino a ( 542) 1019 242.2 3.1e-63
XP_011516312 (OMIM: 133550,615232) PREDICTED: exci ( 477) 972 231.4 4.8e-60
XP_011516311 (OMIM: 133550,615232) PREDICTED: exci ( 504) 972 231.4 5.1e-60
NP_004161 (OMIM: 133550,615232) excitatory amino a ( 524) 972 231.4 5.2e-60
XP_011516310 (OMIM: 133550,615232) PREDICTED: exci ( 527) 972 231.4 5.3e-60
XP_011516309 (OMIM: 133550,615232) PREDICTED: exci ( 547) 972 231.4 5.4e-60
XP_006722907 (OMIM: 600637) PREDICTED: excitatory ( 564) 944 225.0 4.7e-58
XP_006722905 (OMIM: 600637) PREDICTED: excitatory ( 564) 944 225.0 4.7e-58
NP_005062 (OMIM: 600637) excitatory amino acid tra ( 564) 944 225.0 4.7e-58
XP_016882641 (OMIM: 600637) PREDICTED: excitatory ( 564) 944 225.0 4.7e-58
NP_006662 (OMIM: 604471) excitatory amino acid tra ( 560) 909 217.0 1.2e-55
NP_001239581 (OMIM: 600300,617105) excitatory amin ( 565) 905 216.1 2.3e-55
XP_016873627 (OMIM: 600300,617105) PREDICTED: exci ( 565) 905 216.1 2.3e-55
XP_016873626 (OMIM: 600300,617105) PREDICTED: exci ( 565) 905 216.1 2.3e-55
NP_001182657 (OMIM: 600300,617105) excitatory amin ( 565) 905 216.1 2.3e-55
NP_001274526 (OMIM: 604471) excitatory amino acid ( 472) 904 215.8 2.3e-55
XP_011518587 (OMIM: 600300,617105) PREDICTED: exci ( 570) 905 216.1 2.3e-55
XP_005253124 (OMIM: 600300,617105) PREDICTED: exci ( 571) 905 216.1 2.3e-55
NP_004162 (OMIM: 600300,617105) excitatory amino a ( 574) 905 216.1 2.3e-55
XP_016873625 (OMIM: 600300,617105) PREDICTED: exci ( 579) 905 216.1 2.3e-55
NP_001276869 (OMIM: 600111,612656) excitatory amin ( 430) 840 201.2 5.4e-51
NP_001160167 (OMIM: 600111,612656) excitatory amin ( 497) 757 182.2 3.2e-45
NP_001180422 (OMIM: 600229,616657) neutral amino a ( 234) 708 170.9 3.9e-42
XP_016870532 (OMIM: 133550,615232) PREDICTED: exci ( 488) 666 161.4 5.8e-39
XP_016870531 (OMIM: 133550,615232) PREDICTED: exci ( 511) 666 161.4 6e-39
XP_011540304 (OMIM: 604471) PREDICTED: excitatory ( 337) 537 131.8 3.2e-30
NP_001274524 (OMIM: 604471) excitatory amino acid ( 619) 537 131.9 5.5e-30
XP_016873628 (OMIM: 600300,617105) PREDICTED: exci ( 496) 478 118.4 5.2e-26
NP_001259016 (OMIM: 600637) excitatory amino acid ( 312) 430 107.3 7e-23
NP_001259017 (OMIM: 600637) excitatory amino acid ( 312) 430 107.3 7e-23
NP_001274525 (OMIM: 604471) excitatory amino acid ( 158) 293 75.9 1.1e-13
>>NP_005619 (OMIM: 109190) neutral amino acid transporte (541 aa)
initn: 3437 init1: 3437 opt: 3437 Z-score: 4245.7 bits: 795.3 E(85289): 0
Smith-Waterman score: 3437; 99.6% identity (100.0% similar) in 541 aa overlap (1-541:1-541)
10 20 30 40 50 60
pF1KB5 MVADPPRDSKGLAAAEPTANGGLALASIEDQGAAAGGYCGSRDQVRRCLRANLLVLLTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MVADPPRDSKGLAAAEPTANGGLALASIEDQGAAAGGYCGSRDQVRRCLRANLLVLLTVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIILPLVVCSLIGGAASLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIILPLVVCSLIGGAASLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LDSFLDLARNIFPSNLVSAAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILGLVVFAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LDSFLDLARNIFPSNLVSAAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILGLVVFAIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 MKCVEENNGVVKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVT
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 ATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LLQNYVDRTESRSTEPELIQVKSELPLDPLPLPTEEGNPLLKHYRGPAGDATVASEKESV
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_005 LLQNYVDRTESRSTEPELIQVKSELPLDPLPVPTEEGNPLLKHYRGPAGDATVASEKESV
490 500 510 520 530 540
pF1KB5 M
:
NP_005 M
>>XP_005259224 (OMIM: 109190) PREDICTED: neutral amino a (469 aa)
initn: 2932 init1: 2932 opt: 2932 Z-score: 3622.3 bits: 679.8 E(85289): 5e-195
Smith-Waterman score: 2932; 99.8% identity (100.0% similar) in 463 aa overlap (1-463:1-463)
10 20 30 40 50 60
pF1KB5 MVADPPRDSKGLAAAEPTANGGLALASIEDQGAAAGGYCGSRDQVRRCLRANLLVLLTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVADPPRDSKGLAAAEPTANGGLALASIEDQGAAAGGYCGSRDQVRRCLRANLLVLLTVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIILPLVVCSLIGGAASLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIILPLVVCSLIGGAASLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LDSFLDLARNIFPSNLVSAAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILGLVVFAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDSFLDLARNIFPSNLVSAAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILGLVVFAIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 MKCVEENNGVVKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVT
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 ATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAG
:::::::::::::::::::::::::::::::::::::::::::
XP_005 ATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVTSGKTF
430 440 450 460
490 500 510 520 530 540
pF1KB5 LLQNYVDRTESRSTEPELIQVKSELPLDPLPLPTEEGNPLLKHYRGPAGDATVASEKESV
>>NP_001138617 (OMIM: 109190) neutral amino acid transpo (339 aa)
initn: 2166 init1: 2166 opt: 2166 Z-score: 2677.5 bits: 504.5 E(85289): 2.1e-142
Smith-Waterman score: 2166; 99.4% identity (100.0% similar) in 338 aa overlap (204-541:2-339)
180 190 200 210 220 230
pF1KB5 NAPSKEVLDSFLDLARNIFPSNLVSAAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILG
::::::::::::::::::::::::::::::
NP_001 MYSTTYEERNITGTRVKVPVGQEVEGMNILG
10 20 30
240 250 260 270 280 290
pF1KB5 LVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEME
40 50 60 70 80 90
300 310 320 330 340 350
pF1KB5 DVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSS
100 110 120 130 140 150
360 370 380 390 400 410
pF1KB5 SATLPLMMKCVEENNGVVKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVK
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 SATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVK
160 170 180 190 200 210
420 430 440 450 460 470
pF1KB5 IITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVE
220 230 240 250 260 270
480 490 500 510 520 530
pF1KB5 GDALGAGLLQNYVDRTESRSTEPELIQVKSELPLDPLPLPTEEGNPLLKHYRGPAGDATV
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_001 GDALGAGLLQNYVDRTESRSTEPELIQVKSELPLDPLPVPTEEGNPLLKHYRGPAGDATV
280 290 300 310 320 330
540
pF1KB5 ASEKESVM
::::::::
NP_001 ASEKESVM
>>NP_001138616 (OMIM: 109190) neutral amino acid transpo (313 aa)
initn: 2008 init1: 2008 opt: 2008 Z-score: 2482.6 bits: 468.3 E(85289): 1.5e-131
Smith-Waterman score: 2008; 99.4% identity (100.0% similar) in 313 aa overlap (229-541:1-313)
200 210 220 230 240 250
pF1KB5 AAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRF
::::::::::::::::::::::::::::::
NP_001 MNILGLVVFAIVFGVALRKLGPEGELLIRF
10 20 30
260 270 280 290 300 310
pF1KB5 FNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGL
40 50 60 70 80 90
320 330 340 350 360 370
pF1KB5 LVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVVKHISRFI
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_001 LVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVAKHISRFI
100 110 120 130 140 150
380 390 400 410 420 430
pF1KB5 LPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLT
160 170 180 190 200 210
440 450 460 470 480 490
pF1KB5 LAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAGLLQNYVDRTESRSTEPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAGLLQNYVDRTESRSTEPEL
220 230 240 250 260 270
500 510 520 530 540
pF1KB5 IQVKSELPLDPLPLPTEEGNPLLKHYRGPAGDATVASEKESVM
:::::::::::::.:::::::::::::::::::::::::::::
NP_001 IQVKSELPLDPLPVPTEEGNPLLKHYRGPAGDATVASEKESVM
280 290 300 310
>>NP_003029 (OMIM: 600229,616657) neutral amino acid tra (532 aa)
initn: 1798 init1: 1269 opt: 1891 Z-score: 2334.4 bits: 441.7 E(85289): 2.7e-123
Smith-Waterman score: 1891; 60.9% identity (81.9% similar) in 524 aa overlap (32-541:17-532)
10 20 30 40 50
pF1KB5 VADPPRDSKGLAAAEPTANGGLALASIEDQGAAAG-GYCGSR-DQVRRC---LRANLLVL
: ::: : :. ..::: :: . :::
NP_003 MEKSNETNGYLDSAQAGPAAGPGAPGTAAGRARRCAGFLRRQALVL
10 20 30 40
60 70 80 90 100 110
pF1KB5 LTVVAVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIILPLVVCSLIGGA
::: .:.::..:: .. : :.:. ... ..::::.:::.:::::::::::::..::
NP_003 LTVSGVLAGAGLGAALRG----LSLSRTQVTYLAFPGEMLLRMLRMIILPLVVCSLVSGA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 ASLDPGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINAS-VGAAGSAENA
:::: . :::::. :. .: .::: ::::.:.::. ..::... ....: .: :.
NP_003 ASLDASCLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGSGAQTLQSSDLGLEDSGPPP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 PSKEVLDSFLDLARNIFPSNLVSAAFRSYSTTYE---ERNITG--TRVKVPVGQEVEGMN
::..:::::::::.:::::: ::::.:.: :. . . .: :. :.:.: :.::::
NP_003 VPKETVDSFLDLARNLFPSNLVVAAFRTYATDYKVVTQNSSSGNVTHEKIPIGTEIEGMN
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 ILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIV
:::::.::.:.::::.::: ::: :::::::.::::::::::::::.::::::::..:::
NP_003 ILGLVLFALVLGVALKKLGSEGEDLIRFFNSLNEATMVLVSWIMWYVPVGIMFLVGSKIV
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 EMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGT
::.:. .: . :::::. .:::.::: .:::::::.::::::.::: :...:.::::.:
NP_003 EMKDIIVLVTSLGKYIFASILGHVIHGGIVLPLIYFVFTRKNPFRFLLGLLAPFATAFAT
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 SSSSATLPLMMKCVEENNGVVKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLD
::::::: ::::.:::::: :.::::::::::::::::::.::::::::::::.. :.
NP_003 CSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVELN
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB5 FVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVL
.:.:::::::::::::::.:::::::.::::::..::. . :::::::.:::. ::.
NP_003 AGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLPLILAVDWIVDRTTTVV
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB5 NVEGDALGAGLLQNYVDRTESRSTEPELIQVKSELPLDPLPLPTEEGNPLLKHYRGPAGD
::::::::::.:. .... ... : :: .:: : : :: .::. : ..:::
NP_003 NVEGDALGAGILH-HLNQKATKKGEQELAEVKVEAI--PNCKSEEETSPLVTH-QNPAGP
470 480 490 500 510
540
pF1KB5 ATVASE---KESVM
.. : : ::::.
NP_003 VASAPELESKESVL
520 530
>>XP_006712142 (OMIM: 600229,616657) PREDICTED: neutral (312 aa)
initn: 1340 init1: 1255 opt: 1321 Z-score: 1633.3 bits: 311.2 E(85289): 3.1e-84
Smith-Waterman score: 1321; 67.7% identity (85.8% similar) in 316 aa overlap (229-541:1-312)
200 210 220 230 240 250
pF1KB5 AAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRF
:::::::.::.:.::::.::: ::: ::::
XP_006 MNILGLVLFALVLGVALKKLGSEGEDLIRF
10 20 30
260 270 280 290 300 310
pF1KB5 FNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGL
:::.::::::::::::::.::::::::..:::::.:. .: . :::::. .:::.:::
XP_006 FNSLNEATMVLVSWIMWYVPVGIMFLVGSKIVEMKDIIVLVTSLGKYIFASILGHVIHGG
40 50 60 70 80 90
320 330 340 350 360 370
pF1KB5 LVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVVKHISRFI
.:::::::.::::::.::: :...:.::::.: ::::::: ::::.:::::: :.:::::
XP_006 IVLPLIYFVFTRKNPFRFLLGLLAPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFI
100 110 120 130 140 150
380 390 400 410 420 430
pF1KB5 LPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLT
:::::::::::::.::::::::::::.. :. .:.:::::::::::::::.:::::::
XP_006 LPIGATVNMDGAAIFQCVAAVFIAQLNNVELNAGQIFTILVTATASSVGAAGVPAGGVLT
160 170 180 190 200 210
440 450 460 470 480 490
pF1KB5 LAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAGLLQNYVDRTESRSTEPEL
.::::::..::. . :::::::.:::. ::.::::::::::.:. .... ... : ::
XP_006 IAIILEAIGLPTHDLPLILAVDWIVDRTTTVVNVEGDALGAGILH-HLNQKATKKGEQEL
220 230 240 250 260
500 510 520 530 540
pF1KB5 IQVKSELPLDPLPLPTEEGNPLLKHYRGPAGDATVASE---KESVM
.:: : : :: .::. : ..::: .. : : ::::.
XP_006 AEVKVEAI--PNCKSEEETSPLVTH-QNPAGPVASAPELESKESVL
270 280 290 300 310
>>XP_011512386 (OMIM: 600111,612656) PREDICTED: excitato (435 aa)
initn: 1134 init1: 1004 opt: 1019 Z-score: 1257.7 bits: 242.1 E(85289): 2.6e-63
Smith-Waterman score: 1162; 46.1% identity (74.0% similar) in 408 aa overlap (117-498:2-402)
90 100 110 120 130 140
pF1KB5 SAFVFPGELLLRLLRMIILPLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALG
:.:: : :..: :......::..: ..:
XP_011 MAALDSKASGKMGMRAVVYYMTTTIIAVVIG
10 20 30
150 160 170 180 190 200
pF1KB5 VGLALALQPGAASAAINASVGAAGSAENAPSKEVLDSFLDLARNIFPSNLVSAAFRSYST
. ... ..:: .. : . : :.:::: ::.:: ::: : :....:
XP_011 IIIVIIIHPGKGTKENMHREGKIVRVTAA------DAFLDLIRNMFPPNLVEACFKQFKT
40 50 60 70 80
210 220 230 240
pF1KB5 TYEERNI-----------------------TGTRVK---VPVGQEVEGMNILGLVVFAIV
.::.:.. : ::. ::: :.:.: ::::::..
XP_011 NYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMC
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB5 FGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFA
:: .. .. .:. : .::.:.::: : ::. :::::::::.::.:::::::::.:.. .
XP_011 FGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGG
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB5 RLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLM
.:. : . ..: ::...::::.::: :::::. :. :.. : ::.::::::::::.
XP_011 QLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPIT
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB5 MKCVEENNGVVKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVT
.::.:::::: :...::.::.:::.::::.::.. .::.::::... :.: .:::: .:
XP_011 FKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISIT
270 280 290 300 310 320
430 440 450 460 470 480
pF1KB5 ATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAG
:::.:.:::::: .:..:..:.: .:.::.: :.::.::::..:: :. :: ::.::::
XP_011 ATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAG
330 340 350 360 370 380
490 500 510 520 530 540
pF1KB5 LLQNYVDRTESRSTEPELIQVKSELPLDPLPLPTEEGNPLLKHYRGPAGDATVASEKESV
... ...: : .. . :.
XP_011 IVE-HLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
390 400 410 420 430
>>NP_001276868 (OMIM: 600111,612656) excitatory amino ac (496 aa)
initn: 1150 init1: 1004 opt: 1019 Z-score: 1256.8 bits: 242.2 E(85289): 2.9e-63
Smith-Waterman score: 1188; 45.5% identity (73.7% similar) in 426 aa overlap (99-498:45-463)
70 80 90 100 110 120
pF1KB5 GLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIILPLVVCSLIGGAASLDPGALGRLG
:.: .. :.: ..: : :.:: : :..:
NP_001 MERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGMAALDSKASGKMG
20 30 40 50 60 70
130 140 150 160 170 180
pF1KB5 AWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEVLDSFLDLA
:......::..: ..:. ... ..:: .. : . : :.::::
NP_001 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAA------DAFLDLI
80 90 100 110 120
190 200 210 220
pF1KB5 RNIFPSNLVSAAFRSYSTTYEERNI-----------------------TGTRVK---VPV
::.:: ::: : :....:.::.:.. : ::. :::
NP_001 RNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPV
130 140 150 160 170 180
230 240 250 260 270 280
pF1KB5 GQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIM
:.:.: ::::::.. :: .. .. .:. : .::.:.::: : ::. :::::::::.
NP_001 PGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGIL
190 200 210 220 230 240
290 300 310 320 330 340
pF1KB5 FLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVT
::.:::::::::.:.. ..:. : . ..: ::...::::.::: :::::. :. :..
NP_001 FLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQ
250 260 270 280 290 300
350 360 370 380 390 400
pF1KB5 PLATAFGTSSSSATLPLMMKCVEENNGVVKHISRFILPIGATVNMDGAALFQCVAAVFIA
: ::.::::::::::. .::.:::::: :...::.::.:::.::::.::.. .::.:::
NP_001 ALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIA
310 320 330 340 350 360
410 420 430 440 450 460
pF1KB5 QLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWL
:... :.: .:::: .::::.:.:::::: .:..:..:.: .:.::.: :.::.::::.
NP_001 QVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWF
370 380 390 400 410 420
470 480 490 500 510 520
pF1KB5 VDRSCTVLNVEGDALGAGLLQNYVDRTESRSTEPELIQVKSELPLDPLPLPTEEGNPLLK
.:: :. :: ::.::::... ...: : .. . :.
NP_001 LDRLRTTTNVLGDSLGAGIVE-HLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETE
430 440 450 460 470 480
530 540
pF1KB5 HYRGPAGDATVASEKESVM
NP_001 KPIDSETKM
490
>>XP_005248399 (OMIM: 600111,612656) PREDICTED: excitato (542 aa)
initn: 1369 init1: 1004 opt: 1019 Z-score: 1256.2 bits: 242.2 E(85289): 3.1e-63
Smith-Waterman score: 1340; 45.2% identity (72.8% similar) in 489 aa overlap (41-498:37-509)
20 30 40 50 60 70
pF1KB5 GLAAAEPTANGGLALASIEDQGAAAGGYCGSRDQVRRCLRANLLVLLTVVAVVAGVALGL
....:. : : .:::::.::..:. ::.
XP_005 EEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGF
10 20 30 40 50 60
80 90 100 110 120
pF1KB5 GVSGAGGALALGPERLSA-----FVFPGELLLRLLRMIILPLVVCSLIGGAASLDPGALG
.: : :.: : ::::::.:.:.:..:::.. ::. : :.:: : :
XP_005 ---------TLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASG
70 80 90 100 110
130 140 150 160 170 180
pF1KB5 RLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEVLDSFL
..: :......::..: ..:. ... ..:: .. : . : :.::
XP_005 KMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAA------DAFL
120 130 140 150 160 170
190 200 210
pF1KB5 DLARNIFPSNLVSAAFRSYSTTYEERNI-----------------------TGTRVK---
:: ::.:: ::: : :....:.::.:.. : ::.
XP_005 DLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEEL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 VPVGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPV
::: :.:.: ::::::.. :: .. .. .:. : .::.:.::: : ::. :::::::
XP_005 VPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 GIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWG
::.::.:::::::::.:.. ..:. : . ..: ::...::::.::: :::::. :. :
XP_005 GILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 IVTPLATAFGTSSSSATLPLMMKCVEENNGVVKHISRFILPIGATVNMDGAALFQCVAAV
.. : ::.::::::::::. .::.:::::: :...::.::.:::.::::.::.. .::.
XP_005 LLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAI
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB5 FIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAV
::::... :.: .:::: .::::.:.:::::: .:..:..:.: .:.::.: :.::.::
XP_005 FIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAV
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB5 DWLVDRSCTVLNVEGDALGAGLLQNYVDRTESRSTEPELIQVKSELPLDPLPLPTEEGNP
::..:: :. :: ::.::::... ...: : .. . :.
XP_005 DWFLDRLRTTTNVLGDSLGAGIVE-HLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDN
480 490 500 510 520 530
520 530 540
pF1KB5 LLKHYRGPAGDATVASEKESVM
XP_005 ETEKPIDSETKM
540
>>NP_004163 (OMIM: 600111,612656) excitatory amino acid (542 aa)
initn: 1369 init1: 1004 opt: 1019 Z-score: 1256.2 bits: 242.2 E(85289): 3.1e-63
Smith-Waterman score: 1340; 45.2% identity (72.8% similar) in 489 aa overlap (41-498:37-509)
20 30 40 50 60 70
pF1KB5 GLAAAEPTANGGLALASIEDQGAAAGGYCGSRDQVRRCLRANLLVLLTVVAVVAGVALGL
....:. : : .:::::.::..:. ::.
NP_004 EEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGF
10 20 30 40 50 60
80 90 100 110 120
pF1KB5 GVSGAGGALALGPERLSA-----FVFPGELLLRLLRMIILPLVVCSLIGGAASLDPGALG
.: : :.: : ::::::.:.:.:..:::.. ::. : :.:: : :
NP_004 ---------TLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASG
70 80 90 100 110
130 140 150 160 170 180
pF1KB5 RLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEVLDSFL
..: :......::..: ..:. ... ..:: .. : . : :.::
NP_004 KMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAA------DAFL
120 130 140 150 160 170
190 200 210
pF1KB5 DLARNIFPSNLVSAAFRSYSTTYEERNI-----------------------TGTRVK---
:: ::.:: ::: : :....:.::.:.. : ::.
NP_004 DLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEEL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 VPVGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPV
::: :.:.: ::::::.. :: .. .. .:. : .::.:.::: : ::. :::::::
NP_004 VPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 GIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWG
::.::.:::::::::.:.. ..:. : . ..: ::...::::.::: :::::. :. :
NP_004 GILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 IVTPLATAFGTSSSSATLPLMMKCVEENNGVVKHISRFILPIGATVNMDGAALFQCVAAV
.. : ::.::::::::::. .::.:::::: :...::.::.:::.::::.::.. .::.
NP_004 LLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAI
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB5 FIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAV
::::... :.: .:::: .::::.:.:::::: .:..:..:.: .:.::.: :.::.::
NP_004 FIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAV
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB5 DWLVDRSCTVLNVEGDALGAGLLQNYVDRTESRSTEPELIQVKSELPLDPLPLPTEEGNP
::..:: :. :: ::.::::... ...: : .. . :.
NP_004 DWFLDRLRTTTNVLGDSLGAGIVE-HLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDN
480 490 500 510 520 530
520 530 540
pF1KB5 LLKHYRGPAGDATVASEKESVM
NP_004 ETEKPIDSETKM
540
541 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:21:47 2016 done: Sat Nov 5 12:21:48 2016
Total Scan time: 10.950 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]