Result of FASTA (omim) for
pF1KB5048
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5048, 724 aa
1>>>pF1KB5048 724 - 724 aa - 724 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9405+/-0.000524; mu= 13.0232+/- 0.032
mean_var=242.2775+/-53.762, 0's: 0 Z-trim(113.7): 479 B-trim: 533 in 1/55
Lambda= 0.082398
statistics sampled from 22533 (23137) to 22533 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.271), width: 16
Scan time: 9.250
The best scores are: opt bits E(85289)
NP_001308004 (OMIM: 602887) disks large homolog 4 ( 724) 4785 583.6 9.6e-166
NP_001122299 (OMIM: 602887) disks large homolog 4 ( 721) 4751 579.5 1.6e-164
NP_001356 (OMIM: 602887) disks large homolog 4 iso ( 767) 4717 575.5 2.7e-163
NP_001308003 (OMIM: 602887) disks large homolog 4 ( 764) 4683 571.5 4.4e-162
XP_016879777 (OMIM: 602887) PREDICTED: disks large ( 702) 4552 555.8 2.1e-157
XP_005256548 (OMIM: 602887) PREDICTED: disks large ( 754) 4532 553.5 1.1e-156
XP_011522001 (OMIM: 602887) PREDICTED: disks large ( 797) 4532 553.5 1.2e-156
XP_011522000 (OMIM: 602887) PREDICTED: disks large ( 797) 4532 553.5 1.2e-156
XP_016879779 (OMIM: 602887) PREDICTED: disks large ( 697) 4524 552.5 2.1e-156
XP_016879778 (OMIM: 602887) PREDICTED: disks large ( 699) 4518 551.8 3.4e-156
NP_001308006 (OMIM: 602887) disks large homolog 4 ( 664) 4368 533.9 7.7e-151
NP_001308005 (OMIM: 602887) disks large homolog 4 ( 664) 4368 533.9 7.7e-151
XP_011522004 (OMIM: 602887) PREDICTED: disks large ( 664) 4368 533.9 7.7e-151
XP_016861296 (OMIM: 601014) PREDICTED: disks large ( 893) 2442 305.2 7.6e-82
XP_016861298 (OMIM: 601014) PREDICTED: disks large ( 893) 2442 305.2 7.6e-82
XP_016861295 (OMIM: 601014) PREDICTED: disks large ( 893) 2442 305.2 7.6e-82
XP_016861297 (OMIM: 601014) PREDICTED: disks large ( 893) 2442 305.2 7.6e-82
XP_016861306 (OMIM: 601014) PREDICTED: disks large ( 871) 2441 305.0 8.1e-82
XP_016861307 (OMIM: 601014) PREDICTED: disks large ( 871) 2441 305.0 8.1e-82
XP_011510807 (OMIM: 601014) PREDICTED: disks large ( 871) 2441 305.0 8.1e-82
XP_016861305 (OMIM: 601014) PREDICTED: disks large ( 871) 2441 305.0 8.1e-82
XP_016861308 (OMIM: 601014) PREDICTED: disks large ( 871) 2441 305.0 8.1e-82
XP_016861299 (OMIM: 601014) PREDICTED: disks large ( 892) 2441 305.0 8.2e-82
XP_011510805 (OMIM: 601014) PREDICTED: disks large ( 892) 2441 305.0 8.2e-82
NP_001191315 (OMIM: 601014) disks large homolog 1 ( 892) 2441 305.0 8.2e-82
XP_016861310 (OMIM: 601014) PREDICTED: disks large ( 843) 2438 304.6 1e-81
XP_005269346 (OMIM: 601014) PREDICTED: disks large ( 926) 2438 304.7 1.1e-81
NP_004078 (OMIM: 601014) disks large homolog 1 iso ( 926) 2438 304.7 1.1e-81
XP_016861291 (OMIM: 601014) PREDICTED: disks large ( 926) 2438 304.7 1.1e-81
XP_016861290 (OMIM: 601014) PREDICTED: disks large ( 926) 2438 304.7 1.1e-81
XP_016861289 (OMIM: 601014) PREDICTED: disks large ( 926) 2438 304.7 1.1e-81
XP_016861292 (OMIM: 601014) PREDICTED: disks large ( 926) 2438 304.7 1.1e-81
XP_016861312 (OMIM: 601014) PREDICTED: disks large ( 810) 2437 304.5 1.1e-81
XP_016861311 (OMIM: 601014) PREDICTED: disks large ( 821) 2437 304.5 1.1e-81
NP_001091894 (OMIM: 601014) disks large homolog 1 ( 904) 2437 304.6 1.2e-81
NP_001277912 (OMIM: 601014) disks large homolog 1 ( 904) 2437 304.6 1.2e-81
XP_011510804 (OMIM: 601014) PREDICTED: disks large ( 904) 2437 304.6 1.2e-81
XP_016861294 (OMIM: 601014) PREDICTED: disks large ( 904) 2437 304.6 1.2e-81
NP_001191317 (OMIM: 601014) disks large homolog 1 ( 788) 2436 304.4 1.2e-81
NP_001191316 (OMIM: 601014) disks large homolog 1 ( 800) 2436 304.4 1.2e-81
XP_016861293 (OMIM: 601014) PREDICTED: disks large ( 925) 2437 304.6 1.2e-81
XP_016861302 (OMIM: 601014) PREDICTED: disks large ( 875) 2357 295.0 8.3e-79
XP_016861301 (OMIM: 601014) PREDICTED: disks large ( 875) 2357 295.0 8.3e-79
XP_016861303 (OMIM: 601014) PREDICTED: disks large ( 875) 2357 295.0 8.3e-79
XP_016861300 (OMIM: 601014) PREDICTED: disks large ( 875) 2357 295.0 8.3e-79
XP_016861309 (OMIM: 601014) PREDICTED: disks large ( 853) 2356 294.9 8.8e-79
XP_011510808 (OMIM: 601014) PREDICTED: disks large ( 853) 2356 294.9 8.8e-79
XP_016861304 (OMIM: 601014) PREDICTED: disks large ( 874) 2356 294.9 9e-79
NP_066943 (OMIM: 300189,300850) disks large homolo ( 817) 2188 274.9 8.9e-73
XP_006724689 (OMIM: 300189,300850) PREDICTED: disk ( 831) 2188 274.9 8.9e-73
>>NP_001308004 (OMIM: 602887) disks large homolog 4 isof (724 aa)
initn: 4785 init1: 4785 opt: 4785 Z-score: 3096.6 bits: 583.6 E(85289): 9.6e-166
Smith-Waterman score: 4785; 100.0% identity (100.0% similar) in 724 aa overlap (1-724:1-724)
10 20 30 40 50 60
pF1KB5 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
670 680 690 700 710 720
pF1KB5 RERL
::::
NP_001 RERL
>>NP_001122299 (OMIM: 602887) disks large homolog 4 isof (721 aa)
initn: 4753 init1: 4413 opt: 4751 Z-score: 3074.8 bits: 579.5 E(85289): 1.6e-164
Smith-Waterman score: 4751; 99.6% identity (99.6% similar) in 724 aa overlap (1-724:1-721)
10 20 30 40 50 60
pF1KB5 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGE
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_001 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGY---VNGTEGE
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB5 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB5 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB5 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB5 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB5 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
660 670 680 690 700 710
pF1KB5 RERL
::::
NP_001 RERL
720
>>NP_001356 (OMIM: 602887) disks large homolog 4 isoform (767 aa)
initn: 4717 init1: 4717 opt: 4717 Z-score: 3052.7 bits: 575.5 E(85289): 2.7e-163
Smith-Waterman score: 4717; 99.7% identity (100.0% similar) in 716 aa overlap (9-724:52-767)
10 20 30
pF1KB5 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPV
..::::::::::::::::::::::::::::
NP_001 WAPPLLTVLHSDLFQALLDILDYYEASLSESQKYRYQDEDTPPLEHSPAHLPNQANSPPV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB5 IVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITK
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB5 IIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKV
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB5 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB5 GLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYL
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB5 GTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFI
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB5 SFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYS
390 400 410 420 430 440
400 410 420 430 440 450
pF1KB5 RFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGD
450 460 470 480 490 500
460 470 480 490 500 510
pF1KB5 VLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGRED
510 520 530 540 550 560
520 530 540 550 560 570
pF1KB5 SVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGR
570 580 590 600 610 620
580 590 600 610 620 630
pF1KB5 DYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRL
630 640 650 660 670 680
640 650 660 670 680 690
pF1KB5 QAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFE
690 700 710 720 730 740
700 710 720
pF1KB5 EIYHKVKRVIEDLSGPYIWVPARERL
::::::::::::::::::::::::::
NP_001 EIYHKVKRVIEDLSGPYIWVPARERL
750 760
>>NP_001308003 (OMIM: 602887) disks large homolog 4 isof (764 aa)
initn: 4685 init1: 4413 opt: 4683 Z-score: 3030.8 bits: 571.5 E(85289): 4.4e-162
Smith-Waterman score: 4683; 99.3% identity (99.6% similar) in 716 aa overlap (9-724:52-764)
10 20 30
pF1KB5 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPV
..::::::::::::::::::::::::::::
NP_001 WAPPLLTVLHSDLFQALLDILDYYEASLSESQKYRYQDEDTPPLEHSPAHLPNQANSPPV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB5 IVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITK
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVNTDTLEAPGY---VNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITK
90 100 110 120 130
100 110 120 130 140 150
pF1KB5 IIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKV
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB5 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB5 GLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYL
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB5 GTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFI
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB5 SFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYS
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB5 RFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGD
440 450 460 470 480 490
460 470 480 490 500 510
pF1KB5 VLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGRED
500 510 520 530 540 550
520 530 540 550 560 570
pF1KB5 SVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGR
560 570 580 590 600 610
580 590 600 610 620 630
pF1KB5 DYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRL
620 630 640 650 660 670
640 650 660 670 680 690
pF1KB5 QAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFE
680 690 700 710 720 730
700 710 720
pF1KB5 EIYHKVKRVIEDLSGPYIWVPARERL
::::::::::::::::::::::::::
NP_001 EIYHKVKRVIEDLSGPYIWVPARERL
740 750 760
>>XP_016879777 (OMIM: 602887) PREDICTED: disks large hom (702 aa)
initn: 4552 init1: 4552 opt: 4552 Z-score: 2947.0 bits: 555.8 E(85289): 2.1e-157
Smith-Waterman score: 4568; 97.0% identity (97.0% similar) in 724 aa overlap (1-724:1-702)
10 20 30 40 50 60
pF1KB5 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGE
:::::::::: ::::::::::::::::::::::::::::
XP_016 MDCLCIVTTK----------------------ANSPPVIVNTDTLEAPGYELQVNGTEGE
10 20 30
70 80 90 100 110 120
pF1KB5 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB5 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB5 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB5 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB5 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
640 650 660 670 680 690
pF1KB5 RERL
::::
XP_016 RERL
700
>>XP_005256548 (OMIM: 602887) PREDICTED: disks large hom (754 aa)
initn: 4656 init1: 4413 opt: 4532 Z-score: 2933.9 bits: 553.5 E(85289): 1.1e-156
Smith-Waterman score: 4675; 95.2% identity (95.2% similar) in 757 aa overlap (1-724:1-754)
10 20 30
pF1KB5 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQ----------------------------
::::::::::::::::::::::::::::::::
XP_005 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQVNAPELVHVAERNLSHLEAGHGVVGHAH
10 20 30 40 50 60
40 50 60 70 80
pF1KB5 -----ANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPH
:::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_005 LSPFKANSPPVIVNTDTLEAPGY---VNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPH
70 80 90 100 110
90 100 110 120 130 140
pF1KB5 IGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLY
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB5 VMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQ
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB5 IGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQH
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB5 LDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB5 VGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVT
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB5 IIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGF
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB5 LSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDW
480 490 500 510 520 530
510 520 530 540 550 560
pF1KB5 GSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTT
540 550 560 570 580 590
570 580 590 600 610 620
pF1KB5 RPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCI
600 610 620 630 640 650
630 640 650 660 670 680
pF1KB5 LDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTEC
660 670 680 690 700 710
690 700 710 720
pF1KB5 FSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL
:::::::::::::::::::::::::::::::::::::
XP_005 FSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL
720 730 740 750
>>XP_011522001 (OMIM: 602887) PREDICTED: disks large hom (797 aa)
initn: 4588 init1: 4413 opt: 4532 Z-score: 2933.6 bits: 553.5 E(85289): 1.2e-156
Smith-Waterman score: 4607; 94.9% identity (95.2% similar) in 749 aa overlap (9-724:52-797)
10 20 30
pF1KB5 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQ------
..::::::::::::::::::::::
XP_011 WAPPLLTVLHSDLFQALLDILDYYEASLSESQKYRYQDEDTPPLEHSPAHLPNQVNAPEL
30 40 50 60 70 80
40 50 60
pF1KB5 ---------------------------ANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEE
:::::::::::::::::: ::::::::::::
XP_011 VHVAERNLSHLEAGHGVVGHAHLSPFKANSPPVIVNTDTLEAPGY---VNGTEGEMEYEE
90 100 110 120 130
70 80 90 100 110 120
pF1KB5 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV
140 150 160 170 180 190
130 140 150 160 170 180
pF1KB5 REVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPG
200 210 220 230 240 250
190 200 210 220 230 240
pF1KB5 DNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK
260 270 280 290 300 310
250 260 270 280 290 300
pF1KB5 PSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEE
320 330 340 350 360 370
310 320 330 340 350 360
pF1KB5 DIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGV
380 390 400 410 420 430
370 380 390 400 410 420
pF1KB5 DLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRS
440 450 460 470 480 490
430 440 450 460 470 480
pF1KB5 NPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDI
500 510 520 530 540 550
490 500 510 520 530 540
pF1KB5 GFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKD
560 570 580 590 600 610
550 560 570 580 590 600
pF1KB5 RANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYN
620 630 640 650 660 670
610 620 630 640 650 660
pF1KB5 SHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRI
680 690 700 710 720 730
670 680 690 700 710 720
pF1KB5 TEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL
740 750 760 770 780 790
>>XP_011522000 (OMIM: 602887) PREDICTED: disks large hom (797 aa)
initn: 4588 init1: 4413 opt: 4532 Z-score: 2933.6 bits: 553.5 E(85289): 1.2e-156
Smith-Waterman score: 4607; 94.9% identity (95.2% similar) in 749 aa overlap (9-724:52-797)
10 20 30
pF1KB5 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQ------
..::::::::::::::::::::::
XP_011 WAPPLLTVLHSDLFQALLDILDYYEASLSESQKYRYQDEDTPPLEHSPAHLPNQVNAPEL
30 40 50 60 70 80
40 50 60
pF1KB5 ---------------------------ANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEE
:::::::::::::::::: ::::::::::::
XP_011 VHVAERNLSHLEAGHGVVGHAHLSPFKANSPPVIVNTDTLEAPGY---VNGTEGEMEYEE
90 100 110 120 130
70 80 90 100 110 120
pF1KB5 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV
140 150 160 170 180 190
130 140 150 160 170 180
pF1KB5 REVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPG
200 210 220 230 240 250
190 200 210 220 230 240
pF1KB5 DNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK
260 270 280 290 300 310
250 260 270 280 290 300
pF1KB5 PSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEE
320 330 340 350 360 370
310 320 330 340 350 360
pF1KB5 DIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGV
380 390 400 410 420 430
370 380 390 400 410 420
pF1KB5 DLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRS
440 450 460 470 480 490
430 440 450 460 470 480
pF1KB5 NPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDI
500 510 520 530 540 550
490 500 510 520 530 540
pF1KB5 GFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKD
560 570 580 590 600 610
550 560 570 580 590 600
pF1KB5 RANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYN
620 630 640 650 660 670
610 620 630 640 650 660
pF1KB5 SHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRI
680 690 700 710 720 730
670 680 690 700 710 720
pF1KB5 TEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL
740 750 760 770 780 790
>>XP_016879779 (OMIM: 602887) PREDICTED: disks large hom (697 aa)
initn: 4526 init1: 4413 opt: 4524 Z-score: 2929.1 bits: 552.5 E(85289): 2.1e-156
Smith-Waterman score: 4524; 99.4% identity (99.6% similar) in 694 aa overlap (31-724:7-697)
10 20 30 40 50 60
pF1KB5 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGE
.::::::::::::::::::: :::::::
XP_016 MGRTGEHQANSPPVIVNTDTLEAPGY---VNGTEGE
10 20 30
70 80 90 100 110 120
pF1KB5 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB5 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB5 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB5 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB5 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
640 650 660 670 680 690
pF1KB5 RERL
::::
XP_016 RERL
>>XP_016879778 (OMIM: 602887) PREDICTED: disks large hom (699 aa)
initn: 4520 init1: 4413 opt: 4518 Z-score: 2925.2 bits: 551.8 E(85289): 3.4e-156
Smith-Waterman score: 4534; 96.5% identity (96.5% similar) in 724 aa overlap (1-724:1-699)
10 20 30 40 50 60
pF1KB5 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGE
:::::::::: :::::::::::::::::: :::::::
XP_016 MDCLCIVTTK----------------------ANSPPVIVNTDTLEAPGY---VNGTEGE
10 20 30
70 80 90 100 110 120
pF1KB5 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB5 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB5 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB5 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB5 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
640 650 660 670 680 690
pF1KB5 RERL
::::
XP_016 RERL
724 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:49:27 2016 done: Thu Nov 3 15:49:28 2016
Total Scan time: 9.250 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]