Result of FASTA (omim) for
pF1KB5018
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5018, 362 aa
1>>>pF1KB5018 362 - 362 aa - 362 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0888+/-0.000352; mu= -2.4466+/- 0.022
mean_var=266.0102+/-54.849, 0's: 0 Z-trim(123.0): 6 B-trim: 1886 in 1/60
Lambda= 0.078637
statistics sampled from 41956 (41968) to 41956 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.492), width: 16
Scan time: 8.470
The best scores are: opt bits E(85289)
NP_001257291 (OMIM: 600061) UV excision repair pro ( 362) 2344 278.3 1.9e-74
NP_005044 (OMIM: 600061) UV excision repair protei ( 363) 2332 277.0 4.8e-74
NP_001257292 (OMIM: 600061) UV excision repair pro ( 308) 1731 208.7 1.4e-53
NP_001231653 (OMIM: 600062) UV excision repair pro ( 337) 694 91.1 3.9e-18
NP_001231642 (OMIM: 600062) UV excision repair pro ( 388) 694 91.1 4.4e-18
NP_002865 (OMIM: 600062) UV excision repair protei ( 409) 467 65.4 2.6e-10
>>NP_001257291 (OMIM: 600061) UV excision repair protein (362 aa)
initn: 2344 init1: 2344 opt: 2344 Z-score: 1457.8 bits: 278.3 E(85289): 1.9e-74
Smith-Waterman score: 2344; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362)
10 20 30 40 50 60
pF1KB5 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAGENPLEFLRDQPQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAGENPLEFLRDQPQF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGEV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFD
310 320 330 340 350 360
pF1KB5 DE
::
NP_001 DE
>>NP_005044 (OMIM: 600061) UV excision repair protein RA (363 aa)
initn: 1444 init1: 1444 opt: 2332 Z-score: 1450.4 bits: 277.0 E(85289): 4.8e-74
Smith-Waterman score: 2332; 99.7% identity (99.7% similar) in 363 aa overlap (1-362:1-363)
10 20 30 40 50 60
pF1KB5 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV
130 140 150 160 170 180
190 200 210 220 230
pF1KB5 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEA-GENPLEFLRDQPQ
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_005 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAAGENPLEFLRDQPQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 FQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 VGAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VGAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNF
310 320 330 340 350 360
360
pF1KB5 DDE
:::
NP_005 DDE
>>NP_001257292 (OMIM: 600061) UV excision repair protein (308 aa)
initn: 1681 init1: 1444 opt: 1731 Z-score: 1082.9 bits: 208.7 E(85289): 1.4e-53
Smith-Waterman score: 1851; 84.6% identity (84.6% similar) in 363 aa overlap (1-362:1-308)
10 20 30 40 50 60
pF1KB5 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV
130 140 150 160 170 180
190 200 210 220 230
pF1KB5 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEA-GENPLEFLRDQPQ
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_001 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAAGENPLEFLRDQPQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 FQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE
:::::::::::::::::::::::::::::::
NP_001 FQNMRQVIQQNPALLPALLQQLGQENPQLLQ-----------------------------
250 260 270
300 310 320 330 340 350
pF1KB5 VGAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNF
::::::::::::::::::::::::::::::::::
NP_001 --------------------------LKALGFPESLVIQAYFACEKNENLAANFLLSQNF
280 290 300
360
pF1KB5 DDE
:::
NP_001 DDE
>>NP_001231653 (OMIM: 600062) UV excision repair protein (337 aa)
initn: 1012 init1: 360 opt: 694 Z-score: 446.5 bits: 91.1 E(85289): 3.9e-18
Smith-Waterman score: 1020; 54.1% identity (72.9% similar) in 340 aa overlap (48-362:1-337)
20 30 40 50 60 70
pF1KB5 RMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVPIRDYR-IDEKNFVVVMV
.. : .: .: . .. .:.
NP_001 MVTKPKAVSTPAPATTQQSAPASTTAVTSS
10 20 30
80 90 100 110 120 130
pF1KB5 TKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPA-AREDKSPSEESAPTTSPE
: : ..:. . : .::..: : : :: ... :.: :: : ....:.:. : :
NP_001 TTTTVAQAPTPVPALAPTSTPASIT---PASATASSEPAPASAAKQEKPAEKPAETPVAT
40 50 60 70 80
140 150 160 170 180 190
pF1KB5 SVSGSVPSSGSSGRE---EDAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPH
: ... .::.:.: :::.:.::::. ::.:.:::::::::::.:.::::::.:::
NP_001 SPTATDSTSGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPD
90 100 110 120 130 140
200 210 220 230
pF1KB5 RAVEYLLTGIPGSPE------PEH----GSVQESQVSEQPATE--------AGENPLEFL
::::::: ::::. : : . :. : : :. :: .: .:::::
NP_001 RAVEYLLMGIPGDRESQAVVDPPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFL
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB5 RDQPQFQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADIS
:.:::::.:::.:::::.::::::::.:.::::::::::.:::.:::::::: : . .
NP_001 RNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQG
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB5 DVEGE-VGAIGEEAP-QMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAAN
: :.:.: . .::::::::::::::::::::::::.::::::::::::::::::
NP_001 GGGGGGSGGIAEAGSGHMNYIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAAN
270 280 290 300 310 320
360
pF1KB5 FLLSQNFDDE
:::.::::..
NP_001 FLLQQNFDED
330
>>NP_001231642 (OMIM: 600062) UV excision repair protein (388 aa)
initn: 1298 init1: 360 opt: 694 Z-score: 445.7 bits: 91.1 E(85289): 4.4e-18
Smith-Waterman score: 1255; 58.7% identity (74.9% similar) in 387 aa overlap (25-362:2-388)
10 20 30 40 50 60
pF1KB5 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP
::.::::::.:::.:::::::::::::::::.::.
NP_001 MVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTA
10 20 30
70 80 90
pF1KB5 IRDYRIDEKNFVVVMVTKTKA----GQGT---SAP-----------------PEASPTAA
...:.::::::::::::: :: . .: ::: : :. :
NP_001 LKEYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALA
40 50 60 70 80 90
100 110 120 130 140 150
pF1KB5 PESS-TSFPPAPTSGMSHPPPA-AREDKSPSEESAPTTSPESVSGSVPSSGSSGRE---E
: :. .:. :: ... :.: :: : ....:.:. : : : ... .::.:.: :
NP_001 PTSTPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFE
100 110 120 130 140 150
160 170 180 190 200
pF1KB5 DAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPE----
::.:.::::. ::.:.:::::::::::.:.::::::.::: ::::::: ::::. :
NP_001 DATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAV
160 170 180 190 200 210
210 220 230 240 250
pF1KB5 --PEH----GSVQESQVSEQPATE--------AGENPLEFLRDQPQFQNMRQVIQQNPAL
: . :. : : :. :: .: .::::::.:::::.:::.:::::.:
NP_001 VDPPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSL
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB5 LPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE-VGAIGEEAP-QMN
:::::::.:.::::::::::.:::.:::::::: : . . : :.:.: . .::
NP_001 LPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMN
280 290 300 310 320 330
320 330 340 350 360
pF1KB5 YIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFDDE
::::::::::::::::::::::.:::::::::::::::::::::.::::..
NP_001 YIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED
340 350 360 370 380
>>NP_002865 (OMIM: 600062) UV excision repair protein RA (409 aa)
initn: 1398 init1: 400 opt: 467 Z-score: 306.2 bits: 65.4 E(85289): 2.6e-10
Smith-Waterman score: 1261; 58.5% identity (74.9% similar) in 390 aa overlap (5-345:3-392)
10 20 30 40 50 60
pF1KB5 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP
.:::::::::::: ..:.::::.::::::.:::.:::::::::::::::::.::.
NP_002 MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTA
10 20 30 40 50
70 80 90
pF1KB5 IRDYRIDEKNFVVVMVTKTKA----GQGT---SAP-----------------PEASPTAA
...:.::::::::::::: :: . .: ::: : :. :
NP_002 LKEYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALA
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB5 PESS-TSFPPAPTSGMSHPPPA-AREDKSPSEESAPTTSPESVSGSVPSSGSSGRE---E
: :. .:. :: ... :.: :: : ....:.:. : : : ... .::.:.: :
NP_002 PTSTPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFE
120 130 140 150 160 170
160 170 180 190 200
pF1KB5 DAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPE----
::.:.::::. ::.:.:::::::::::.:.::::::.::: ::::::: ::::. :
NP_002 DATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAV
180 190 200 210 220 230
210 220 230 240 250
pF1KB5 --PEH----GSVQESQVSEQPATE--------AGENPLEFLRDQPQFQNMRQVIQQNPAL
: . :. : : :. :: .: .::::::.:::::.:::.:::::.:
NP_002 VDPPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSL
240 250 260 270 280 290
260 270 280 290 300 310
pF1KB5 LPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE-VGAIGEEAP-QMN
:::::::.:.::::::::::.:::.:::::::: : . . : :.:.: . .::
NP_002 LPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMN
300 310 320 330 340 350
320 330 340 350 360
pF1KB5 YIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFDDE
::::::::::::::::::::::.:::::::::::
NP_002 YIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED
360 370 380 390 400
362 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:21:10 2016 done: Fri Nov 4 03:21:11 2016
Total Scan time: 8.470 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]