Result of FASTA (omim) for
pF1KB5011
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5011, 417 aa
1>>>pF1KB5011 417 - 417 aa - 417 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0129+/-0.000513; mu= 13.2673+/- 0.032
mean_var=74.0634+/-15.291, 0's: 0 Z-trim(108.2): 26 B-trim: 559 in 1/48
Lambda= 0.149030
statistics sampled from 16295 (16307) to 16295 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.55), E-opt: 0.2 (0.191), width: 16
Scan time: 8.010
The best scores are: opt bits E(85289)
NP_001274671 (OMIM: 184420) squalene synthase isof ( 417) 2776 606.8 3.1e-173
NP_001274672 (OMIM: 184420) squalene synthase isof ( 417) 2776 606.8 3.1e-173
NP_004453 (OMIM: 184420) squalene synthase isoform ( 417) 2776 606.8 3.1e-173
NP_001274679 (OMIM: 184420) squalene synthase isof ( 476) 2548 557.8 2e-158
NP_001274674 (OMIM: 184420) squalene synthase isof ( 353) 2349 515.0 1.2e-145
NP_001274673 (OMIM: 184420) squalene synthase isof ( 353) 2349 515.0 1.2e-145
NP_001274678 (OMIM: 184420) squalene synthase isof ( 353) 2349 515.0 1.2e-145
NP_001274677 (OMIM: 184420) squalene synthase isof ( 353) 2349 515.0 1.2e-145
XP_016868706 (OMIM: 184420) PREDICTED: squalene sy ( 353) 2349 515.0 1.2e-145
NP_001274676 (OMIM: 184420) squalene synthase isof ( 353) 2349 515.0 1.2e-145
NP_001274680 (OMIM: 184420) squalene synthase isof ( 332) 2212 485.5 8.2e-137
NP_001274685 (OMIM: 184420) squalene synthase isof ( 250) 1512 335.0 1.3e-91
>>NP_001274671 (OMIM: 184420) squalene synthase isoform (417 aa)
initn: 2776 init1: 2776 opt: 2776 Z-score: 3231.0 bits: 606.8 E(85289): 3.1e-173
Smith-Waterman score: 2776; 100.0% identity (100.0% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KB5 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 IGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 AACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
370 380 390 400 410
>>NP_001274672 (OMIM: 184420) squalene synthase isoform (417 aa)
initn: 2776 init1: 2776 opt: 2776 Z-score: 3231.0 bits: 606.8 E(85289): 3.1e-173
Smith-Waterman score: 2776; 100.0% identity (100.0% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KB5 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 IGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 AACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
370 380 390 400 410
>>NP_004453 (OMIM: 184420) squalene synthase isoform 1 [ (417 aa)
initn: 2776 init1: 2776 opt: 2776 Z-score: 3231.0 bits: 606.8 E(85289): 3.1e-173
Smith-Waterman score: 2776; 100.0% identity (100.0% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KB5 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 IGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 AACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
370 380 390 400 410
>>NP_001274679 (OMIM: 184420) squalene synthase isoform (476 aa)
initn: 2548 init1: 2548 opt: 2548 Z-score: 2965.1 bits: 557.8 E(85289): 2e-158
Smith-Waterman score: 2548; 100.0% identity (100.0% similar) in 385 aa overlap (33-417:92-476)
10 20 30 40 50 60
pF1KB5 FVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALD
::::::::::::::::::::::::::::::
NP_001 LPQSHSHSHSHSHSHSCSSTSPTAVCVVCPQDSLSSSLKTCYKYLNQTSRSFAAVIQALD
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB5 GEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVL
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB5 EDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIG
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB5 LSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKK
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB5 LGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAA
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB5 CYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQI
370 380 390 400 410 420
370 380 390 400 410
pF1KB5 ISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
430 440 450 460 470
>>NP_001274674 (OMIM: 184420) squalene synthase isoform (353 aa)
initn: 2349 init1: 2349 opt: 2349 Z-score: 2736.0 bits: 515.0 E(85289): 1.2e-145
Smith-Waterman score: 2349; 100.0% identity (100.0% similar) in 353 aa overlap (65-417:1-353)
40 50 60 70 80 90
pF1KB5 SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKV
::::::::::::::::::::::::::::::
NP_001 MRNAVCIFYLVLRALDTLEDDMTISVEKKV
10 20 30
100 110 120 130 140 150
pF1KB5 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
280 290 300 310 320 330
400 410
pF1KB5 ALSWQYLTTLSQVTEDYVQTGEH
:::::::::::::::::::::::
NP_001 ALSWQYLTTLSQVTEDYVQTGEH
340 350
>>NP_001274673 (OMIM: 184420) squalene synthase isoform (353 aa)
initn: 2349 init1: 2349 opt: 2349 Z-score: 2736.0 bits: 515.0 E(85289): 1.2e-145
Smith-Waterman score: 2349; 100.0% identity (100.0% similar) in 353 aa overlap (65-417:1-353)
40 50 60 70 80 90
pF1KB5 SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKV
::::::::::::::::::::::::::::::
NP_001 MRNAVCIFYLVLRALDTLEDDMTISVEKKV
10 20 30
100 110 120 130 140 150
pF1KB5 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
280 290 300 310 320 330
400 410
pF1KB5 ALSWQYLTTLSQVTEDYVQTGEH
:::::::::::::::::::::::
NP_001 ALSWQYLTTLSQVTEDYVQTGEH
340 350
>>NP_001274678 (OMIM: 184420) squalene synthase isoform (353 aa)
initn: 2349 init1: 2349 opt: 2349 Z-score: 2736.0 bits: 515.0 E(85289): 1.2e-145
Smith-Waterman score: 2349; 100.0% identity (100.0% similar) in 353 aa overlap (65-417:1-353)
40 50 60 70 80 90
pF1KB5 SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKV
::::::::::::::::::::::::::::::
NP_001 MRNAVCIFYLVLRALDTLEDDMTISVEKKV
10 20 30
100 110 120 130 140 150
pF1KB5 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
280 290 300 310 320 330
400 410
pF1KB5 ALSWQYLTTLSQVTEDYVQTGEH
:::::::::::::::::::::::
NP_001 ALSWQYLTTLSQVTEDYVQTGEH
340 350
>>NP_001274677 (OMIM: 184420) squalene synthase isoform (353 aa)
initn: 2349 init1: 2349 opt: 2349 Z-score: 2736.0 bits: 515.0 E(85289): 1.2e-145
Smith-Waterman score: 2349; 100.0% identity (100.0% similar) in 353 aa overlap (65-417:1-353)
40 50 60 70 80 90
pF1KB5 SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKV
::::::::::::::::::::::::::::::
NP_001 MRNAVCIFYLVLRALDTLEDDMTISVEKKV
10 20 30
100 110 120 130 140 150
pF1KB5 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
280 290 300 310 320 330
400 410
pF1KB5 ALSWQYLTTLSQVTEDYVQTGEH
:::::::::::::::::::::::
NP_001 ALSWQYLTTLSQVTEDYVQTGEH
340 350
>>XP_016868706 (OMIM: 184420) PREDICTED: squalene syntha (353 aa)
initn: 2349 init1: 2349 opt: 2349 Z-score: 2736.0 bits: 515.0 E(85289): 1.2e-145
Smith-Waterman score: 2349; 100.0% identity (100.0% similar) in 353 aa overlap (65-417:1-353)
40 50 60 70 80 90
pF1KB5 SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKV
::::::::::::::::::::::::::::::
XP_016 MRNAVCIFYLVLRALDTLEDDMTISVEKKV
10 20 30
100 110 120 130 140 150
pF1KB5 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
280 290 300 310 320 330
400 410
pF1KB5 ALSWQYLTTLSQVTEDYVQTGEH
:::::::::::::::::::::::
XP_016 ALSWQYLTTLSQVTEDYVQTGEH
340 350
>>NP_001274676 (OMIM: 184420) squalene synthase isoform (353 aa)
initn: 2349 init1: 2349 opt: 2349 Z-score: 2736.0 bits: 515.0 E(85289): 1.2e-145
Smith-Waterman score: 2349; 100.0% identity (100.0% similar) in 353 aa overlap (65-417:1-353)
40 50 60 70 80 90
pF1KB5 SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKV
::::::::::::::::::::::::::::::
NP_001 MRNAVCIFYLVLRALDTLEDDMTISVEKKV
10 20 30
100 110 120 130 140 150
pF1KB5 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGM
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLA
280 290 300 310 320 330
400 410
pF1KB5 ALSWQYLTTLSQVTEDYVQTGEH
:::::::::::::::::::::::
NP_001 ALSWQYLTTLSQVTEDYVQTGEH
340 350
417 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:15:59 2016 done: Sat Nov 5 06:16:00 2016
Total Scan time: 8.010 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]