Result of FASTA (omim) for
pF1KB5005
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5005, 418 aa
1>>>pF1KB5005 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9373+/-0.000388; mu= 19.7910+/- 0.024
mean_var=73.2230+/-14.914, 0's: 0 Z-trim(111.8): 130 B-trim: 0 in 0/55
Lambda= 0.149882
statistics sampled from 20347 (20484) to 20347 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.24), width: 16
Scan time: 7.690
The best scores are: opt bits E(85289)
XP_011543629 (OMIM: 600943,610504,613848) PREDICTE ( 418) 2692 591.7 1.1e-168
NP_001193943 (OMIM: 600943,610504,613848) serpin H ( 418) 2692 591.7 1.1e-168
NP_001226 (OMIM: 600943,610504,613848) serpin H1 p ( 418) 2692 591.7 1.1e-168
NP_002631 (OMIM: 601697,617115) serpin B8 isoform ( 374) 628 145.3 2.4e-34
NP_942130 (OMIM: 601697,617115) serpin B8 isoform ( 374) 628 145.3 2.4e-34
NP_001258751 (OMIM: 173321,613453) serpin B6 isofo ( 390) 613 142.1 2.3e-33
NP_001258752 (OMIM: 173321,613453) serpin B6 isofo ( 395) 612 141.9 2.7e-33
XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 i ( 376) 610 141.4 3.5e-33
NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens] ( 376) 610 141.4 3.5e-33
NP_001182220 (OMIM: 173321,613453) serpin B6 isofo ( 380) 609 141.2 4.1e-33
XP_016866429 (OMIM: 173321,613453) PREDICTED: serp ( 380) 609 141.2 4.1e-33
XP_011512975 (OMIM: 173321,613453) PREDICTED: serp ( 376) 608 141.0 4.8e-33
NP_001258753 (OMIM: 173321,613453) serpin B6 isofo ( 376) 608 141.0 4.8e-33
NP_001284628 (OMIM: 173321,613453) serpin B6 isofo ( 376) 608 141.0 4.8e-33
NP_001284629 (OMIM: 173321,613453) serpin B6 isofo ( 376) 608 141.0 4.8e-33
NP_001258754 (OMIM: 173321,613453) serpin B6 isofo ( 376) 608 141.0 4.8e-33
XP_011512976 (OMIM: 173321,613453) PREDICTED: serp ( 376) 608 141.0 4.8e-33
NP_004559 (OMIM: 173321,613453) serpin B6 isoform ( 376) 608 141.0 4.8e-33
XP_011512974 (OMIM: 173321,613453) PREDICTED: serp ( 454) 608 141.1 5.5e-33
NP_001121178 (OMIM: 107400,606963,613490) alpha-1- ( 418) 565 131.8 3.2e-30
NP_001121179 (OMIM: 107400,606963,613490) alpha-1- ( 418) 565 131.8 3.2e-30
NP_001002235 (OMIM: 107400,606963,613490) alpha-1- ( 418) 565 131.8 3.2e-30
NP_001002236 (OMIM: 107400,606963,613490) alpha-1- ( 418) 565 131.8 3.2e-30
NP_001121172 (OMIM: 107400,606963,613490) alpha-1- ( 418) 565 131.8 3.2e-30
NP_001121175 (OMIM: 107400,606963,613490) alpha-1- ( 418) 565 131.8 3.2e-30
NP_001121177 (OMIM: 107400,606963,613490) alpha-1- ( 418) 565 131.8 3.2e-30
NP_001121176 (OMIM: 107400,606963,613490) alpha-1- ( 418) 565 131.8 3.2e-30
XP_016876859 (OMIM: 107400,606963,613490) PREDICTE ( 418) 565 131.8 3.2e-30
NP_000286 (OMIM: 107400,606963,613490) alpha-1-ant ( 418) 565 131.8 3.2e-30
NP_001121174 (OMIM: 107400,606963,613490) alpha-1- ( 418) 565 131.8 3.2e-30
NP_001121173 (OMIM: 107400,606963,613490) alpha-1- ( 418) 565 131.8 3.2e-30
NP_002630 (OMIM: 154790) serpin B5 [Homo sapiens] ( 375) 559 130.4 7.4e-30
NP_000615 (OMIM: 601841) plasma serine protease in ( 406) 556 129.8 1.2e-29
XP_011512636 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 536 125.4 2.3e-28
XP_011512635 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 536 125.4 2.3e-28
NP_109591 (OMIM: 130135) leukocyte elastase inhibi ( 379) 536 125.4 2.3e-28
NP_005015 (OMIM: 602058) serpin B10 [Homo sapiens] ( 397) 525 123.1 1.3e-27
XP_011524329 (OMIM: 602058) PREDICTED: serpin B10 ( 397) 525 123.1 1.3e-27
NP_001137290 (OMIM: 173390) plasminogen activator ( 415) 521 122.2 2.4e-27
NP_002566 (OMIM: 173390) plasminogen activator inh ( 415) 521 122.2 2.4e-27
XP_011512978 (OMIM: 173321,613453) PREDICTED: serp ( 332) 513 120.4 6.6e-27
XP_016866430 (OMIM: 173321,613453) PREDICTED: serp ( 332) 513 120.4 6.6e-27
NP_006208 (OMIM: 605587) serpin I2 isoform 2 precu ( 405) 508 119.4 1.6e-26
NP_001012303 (OMIM: 605587) serpin I2 isoform 1 pr ( 415) 508 119.4 1.7e-26
XP_016866432 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 501 117.8 3.9e-26
XP_011512980 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 501 117.8 3.9e-26
XP_016866431 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 501 117.8 3.9e-26
NP_536723 (OMIM: 615682) serpin B11 isoform a [Hom ( 392) 498 117.2 7.1e-26
XP_011524553 (OMIM: 615682) PREDICTED: serpin B11 ( 392) 498 117.2 7.1e-26
NP_001076 (OMIM: 107280) alpha-1-antichymotrypsin ( 423) 492 116.0 1.8e-25
>>XP_011543629 (OMIM: 600943,610504,613848) PREDICTED: s (418 aa)
initn: 2692 init1: 2692 opt: 2692 Z-score: 3149.1 bits: 591.7 E(85289): 1.1e-168
Smith-Waterman score: 2692; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KB5 MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
370 380 390 400 410
>>NP_001193943 (OMIM: 600943,610504,613848) serpin H1 pr (418 aa)
initn: 2692 init1: 2692 opt: 2692 Z-score: 3149.1 bits: 591.7 E(85289): 1.1e-168
Smith-Waterman score: 2692; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KB5 MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
370 380 390 400 410
>>NP_001226 (OMIM: 600943,610504,613848) serpin H1 precu (418 aa)
initn: 2692 init1: 2692 opt: 2692 Z-score: 3149.1 bits: 591.7 E(85289): 1.1e-168
Smith-Waterman score: 2692; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KB5 MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
370 380 390 400 410
>>NP_002631 (OMIM: 601697,617115) serpin B8 isoform a [H (374 aa)
initn: 388 init1: 119 opt: 628 Z-score: 737.7 bits: 145.3 E(85289): 2.4e-34
Smith-Waterman score: 628; 31.3% identity (63.4% similar) in 377 aa overlap (43-409:4-374)
20 30 40 50 60 70
pF1KB5 LEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSPV
: : .. .:.::.. ..... .:.. ::.
NP_002 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPM
10 20 30
80 90 100 110 120 130
pF1KB5 VVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGS
..:.:..: .:.:..::.: . .: .: ..: :. :: : : :. . . ..
NP_002 SISSALAMVFMGAKGSTAAQMSQALCL--YKDGDIHRGFQSLL-SEVNRTGTQYLLRTAN
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 RLYGPSSVSFADDFVRSSKQHYNCEHSKINF-RDKRSALQSINEWAAQTTDGKLPEVTK-
::.: .. .: :: . .. :. : ...: .: . . ::.:.:. :.::. ::
NP_002 RLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDA
100 110 120 130 140 150
200 210 220 230 240
pF1KB5 -DVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMV-TRSYTVGVMMMHRTGLYNY-YD
:. .::::..:: .:.:.: .:.. ::.. : :.:: . . ... :
NP_002 GTVDPLTKLVLVNAIYFKGKWNEQFDRKYT--RGMLFKTNEEKKTVQMMFKEAKFKMGYA
160 170 180 190 200
250 260 270 280 290 300
pF1KB5 DEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMG--KMQKKAVAIS
:: . :..:.: ... :..::.: : .:: :: :..: : . :. :. : .
NP_002 DEVHT-QVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVF
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB5 LPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNP
::. .: ..::. : ::. .:.:. :::.: :: .:.. :..: : :.. .:.
NP_002 LPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTE
270 280 290 300 310 320
370 380 390 400 410
pF1KB5 FDQDIYGREELRSPKL---FYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
.. : .. : :::::.:..: ... .:: ::. :
NP_002 AAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP
330 340 350 360 370
>>NP_942130 (OMIM: 601697,617115) serpin B8 isoform a [H (374 aa)
initn: 388 init1: 119 opt: 628 Z-score: 737.7 bits: 145.3 E(85289): 2.4e-34
Smith-Waterman score: 628; 31.3% identity (63.4% similar) in 377 aa overlap (43-409:4-374)
20 30 40 50 60 70
pF1KB5 LEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSPV
: : .. .:.::.. ..... .:.. ::.
NP_942 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPM
10 20 30
80 90 100 110 120 130
pF1KB5 VVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGS
..:.:..: .:.:..::.: . .: .: ..: :. :: : : :. . . ..
NP_942 SISSALAMVFMGAKGSTAAQMSQALCL--YKDGDIHRGFQSLL-SEVNRTGTQYLLRTAN
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 RLYGPSSVSFADDFVRSSKQHYNCEHSKINF-RDKRSALQSINEWAAQTTDGKLPEVTK-
::.: .. .: :: . .. :. : ...: .: . . ::.:.:. :.::. ::
NP_942 RLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDA
100 110 120 130 140 150
200 210 220 230 240
pF1KB5 -DVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMV-TRSYTVGVMMMHRTGLYNY-YD
:. .::::..:: .:.:.: .:.. ::.. : :.:: . . ... :
NP_942 GTVDPLTKLVLVNAIYFKGKWNEQFDRKYT--RGMLFKTNEEKKTVQMMFKEAKFKMGYA
160 170 180 190 200
250 260 270 280 290 300
pF1KB5 DEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMG--KMQKKAVAIS
:: . :..:.: ... :..::.: : .:: :: :..: : . :. :. : .
NP_942 DEVHT-QVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVF
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB5 LPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNP
::. .: ..::. : ::. .:.:. :::.: :: .:.. :..: : :.. .:.
NP_942 LPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTE
270 280 290 300 310 320
370 380 390 400 410
pF1KB5 FDQDIYGREELRSPKL---FYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
.. : .. : :::::.:..: ... .:: ::. :
NP_942 AAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP
330 340 350 360 370
>>NP_001258751 (OMIM: 173321,613453) serpin B6 isoform c (390 aa)
initn: 412 init1: 167 opt: 613 Z-score: 719.9 bits: 142.1 E(85289): 2.3e-33
Smith-Waterman score: 613; 29.4% identity (65.2% similar) in 394 aa overlap (25-409:3-390)
10 20 30 40 50 60
pF1KB5 MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
:: . :: . : .::: .. .:..: ....:
NP_001 MGAAQSLPG---HRSAIMDVLAEANGTFALNLLKTLGK
10 20 30
70 80 90 100 110
pF1KB5 DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDE-EVHAGLGELLRSLS
:.. .:.. ::. .. .:..: .:.:..::.: .:: .. ..: :. :: .
NP_001 DNS-KNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEV-
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB5 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDK-RSALQSINEWAA
:.:. . ....::.: .: .: ..: : .. :. : ...: . ... . :: :.:
NP_001 NKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVA
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB5 QTTDGKLPEVTK--DVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMM
. :.::. :. . .:. .::::..:. .:::.: .. ...: : :... :.:
NP_001 EKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQM
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB5 MHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIW--M
: . . .. . ::. .: . : ..::..: .. :. .:: :: :.. : .
NP_001 MFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRL
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB5 GKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHA
:... : .:::. .: ..:... : .::.:.:.. .:::.: :: . :: :..: :
NP_001 DMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMS-QTDLSLSKVVHK
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB5 TAFELDTDGNPFDQDIYGREELRSPKL---FYADHPFIFLVRDTQSGSLLFIGRLVRPKG
. :.. .:. . .: .. : :::::.:... ......:: ::. :
NP_001 SFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP
340 350 360 370 380 390
pF1KB5 DKMRDEL
>>NP_001258752 (OMIM: 173321,613453) serpin B6 isoform d (395 aa)
initn: 381 init1: 167 opt: 612 Z-score: 718.7 bits: 141.9 E(85289): 2.7e-33
Smith-Waterman score: 612; 29.7% identity (66.1% similar) in 387 aa overlap (35-409:12-395)
10 20 30 40 50 60
pF1KB5 LLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAA---TLAERSAGLAFSLYQAMAKD
::. :.: .::: .. .:..: ....::
NP_001 MSSRQRGNFNYKLAFKSAIMDVLAEANGTFALNLLKTLGKD
10 20 30 40
70 80 90 100 110 120
pF1KB5 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDE-EVHAGLGELLRSLSN
.. .:.. ::. .. .:..: .:.:..::.: .:: .. ..: :. :: . :
NP_001 NS-KNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEV-N
50 60 70 80 90
130 140 150 160 170
pF1KB5 STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDK-RSALQSINEWAAQ
.:. . ....::.: .: .: ..: : .. :. : ...: . ... . :: :.:.
NP_001 KTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB5 TTDGKLPEVTK--DVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMM
:.::. :. . .:. .::::..:. .:::.: .. ...: : :... :.::
NP_001 KTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMM
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB5 HRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIW--MG
. . .. . ::. .: . : ..::..: .. :. .:: :: :.. : .
NP_001 FKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLD
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB5 KMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHAT
:... : .:::. .: ..:... : .::.:.:.. .:::.: :: . :: :..: : .
NP_001 MMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMS-QTDLSLSKVVHKS
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB5 AFELDTDGNPFDQDIYGREELRSPKL---FYADHPFIFLVRDTQSGSLLFIGRLVRPKGD
:.. .:. . .: .. : :::::.:... ......:: ::. :
NP_001 FVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP
340 350 360 370 380 390
pF1KB5 KMRDEL
>>XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 isofo (376 aa)
initn: 498 init1: 178 opt: 610 Z-score: 716.6 bits: 141.4 E(85289): 3.5e-33
Smith-Waterman score: 610; 29.7% identity (63.9% similar) in 377 aa overlap (42-409:3-376)
20 30 40 50 60 70
pF1KB5 LLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSP
::.. :. .:. : . . .:. .:.. ::
XP_005 METLSNASGTFAIRLLKILCQDNPSHNVFCSP
10 20 30
80 90 100 110 120 130
pF1KB5 VVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLG
: ..:.:..: ::.:..::.: .:: . .:..: .. :: . :... . . .
XP_005 VSISSALAMVLLGAKGNTATQMAQALSLNT--EEDIHRAFQSLLTEV-NKAGTQYLLRTA
40 50 60 70 80
140 150 160 170 180
pF1KB5 SRLYGPSSVSFADDFVRSSKQHYNCEHSKINF-RDKRSALQSINEWAAQTTDGKLPEVT-
.::.: .. .: . : .: : :. : ....: : . . . :: :... :.::. :.
XP_005 NRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEELLP
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB5 -KDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDD
.... .::::..:: .:.: : . .. . : ... :.::.. . ..
XP_005 GSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKLAHV
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB5 EKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGK--MQKKAVAISL
. . :..:.: :.: ::..:.: : .:: :: :.: : :.. : . :
XP_005 GEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLL
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB5 PKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPF
:: .. .:... : ::...:....::::: ::...:: :.. : . :.. .:.
XP_005 PKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEA
270 280 290 300 310 320
370 380 390 400 410
pF1KB5 DQD----IYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
. .. ..: : :::::.:..: ....:.:: ::. :
XP_005 AAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP
330 340 350 360 370
>>NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens] (376 aa)
initn: 498 init1: 178 opt: 610 Z-score: 716.6 bits: 141.4 E(85289): 3.5e-33
Smith-Waterman score: 610; 29.7% identity (63.9% similar) in 377 aa overlap (42-409:3-376)
20 30 40 50 60 70
pF1KB5 LLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSP
::.. :. .:. : . . .:. .:.. ::
NP_004 METLSNASGTFAIRLLKILCQDNPSHNVFCSP
10 20 30
80 90 100 110 120 130
pF1KB5 VVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLG
: ..:.:..: ::.:..::.: .:: . .:..: .. :: . :... . . .
NP_004 VSISSALAMVLLGAKGNTATQMAQALSLNT--EEDIHRAFQSLLTEV-NKAGTQYLLRTA
40 50 60 70 80
140 150 160 170 180
pF1KB5 SRLYGPSSVSFADDFVRSSKQHYNCEHSKINF-RDKRSALQSINEWAAQTTDGKLPEVT-
.::.: .. .: . : .: : :. : ....: : . . . :: :... :.::. :.
NP_004 NRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEELLP
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB5 -KDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDD
.... .::::..:: .:.: : . .. . : ... :.::.. . ..
NP_004 GSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKLAHV
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB5 EKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGK--MQKKAVAISL
. . :..:.: :.: ::..:.: : .:: :: :.: : :.. : . :
NP_004 GEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLL
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB5 PKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPF
:: .. .:... : ::...:....::::: ::...:: :.. : . :.. .:.
NP_004 PKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEA
270 280 290 300 310 320
370 380 390 400 410
pF1KB5 DQD----IYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
. .. ..: : :::::.:..: ....:.:: ::. :
NP_004 AAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP
330 340 350 360 370
>>NP_001182220 (OMIM: 173321,613453) serpin B6 isoform b (380 aa)
initn: 381 init1: 167 opt: 609 Z-score: 715.4 bits: 141.2 E(85289): 4.1e-33
Smith-Waterman score: 609; 29.2% identity (65.8% similar) in 383 aa overlap (36-409:1-380)
10 20 30 40 50 60
pF1KB5 LLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVE
.: .::: .. .:..: ....::.. .
NP_001 MSAIMDVLAEANGTFALNLLKTLGKDNS-K
10 20
70 80 90 100 110 120
pF1KB5 NILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDE-EVHAGLGELLRSLSNSTAR
:.. ::. .. .:..: .:.:..::.: .:: .. ..: :. :: . :.:.
NP_001 NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEV-NKTGT
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB5 NVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDK-RSALQSINEWAAQTTDG
. ....::.: .: .: ..: : .. :. : ...: . ... . :: :.:. :.:
NP_001 QYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEG
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB5 KLPEVTK--DVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTG
:. :. . .:. .::::..:. .:::.: .. ...: : :... :.:: . .
NP_001 KIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQS
150 160 170 180 190 200
250 260 270 280 290
pF1KB5 LYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIW--MGKMQK
.. . ::. .: . : ..::..: .. :. .:: :: :.. : . :..
NP_001 TFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDE
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB5 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL
. : .:::. .: ..:... : .::.:.:.. .:::.: :: . :: :..: : . :.
NP_001 EEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMS-QTDLSLSKVVHKSFVEV
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB5 DTDGNPFDQDIYGREELRSPKL---FYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRD
. .:. . .: .. : :::::.:... ......:: ::. :
NP_001 NEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP
330 340 350 360 370 380
pF1KB5 EL
418 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:14:48 2016 done: Sat Nov 5 06:14:49 2016
Total Scan time: 7.690 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]