Result of FASTA (omim) for
pF1KB4865
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4865, 923 aa
1>>>pF1KB4865 923 - 923 aa - 923 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3993+/-0.000405; mu= 20.4461+/- 0.025
mean_var=71.4290+/-14.555, 0's: 0 Z-trim(112.0): 319 B-trim: 42 in 1/49
Lambda= 0.151753
statistics sampled from 20429 (20786) to 20429 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.244), width: 16
Scan time: 9.810
The best scores are: opt bits E(85289)
NP_003864 (OMIM: 602069) neuropilin-1 isoform a pr ( 923) 6385 1407.9 0
XP_006717584 (OMIM: 602069) PREDICTED: neuropilin- ( 924) 6368 1404.2 0
NP_001231902 (OMIM: 602069) neuropilin-1 isoform e ( 916) 6312 1391.9 0
NP_001231901 (OMIM: 602069) neuropilin-1 isoform d ( 917) 6300 1389.3 0
NP_001316997 (OMIM: 602069) neuropilin-1 isoform f ( 906) 5644 1245.7 0
XP_006717585 (OMIM: 602069) PREDICTED: neuropilin- ( 907) 5627 1242.0 0
XP_016872354 (OMIM: 602069) PREDICTED: neuropilin- ( 899) 5566 1228.6 0
XP_016872355 (OMIM: 602069) PREDICTED: neuropilin- ( 742) 5088 1123.9 0
NP_001019799 (OMIM: 602069) neuropilin-1 isoform b ( 644) 4433 980.5 0
XP_006717589 (OMIM: 602069) PREDICTED: neuropilin- ( 663) 4428 979.4 0
XP_011518057 (OMIM: 602069) PREDICTED: neuropilin- ( 656) 4355 963.4 0
XP_006717588 (OMIM: 602069) PREDICTED: neuropilin- ( 888) 4073 901.7 0
XP_006717587 (OMIM: 602069) PREDICTED: neuropilin- ( 889) 4073 901.7 0
NP_001019800 (OMIM: 602069) neuropilin-1 isoform c ( 609) 4070 901.0 0
XP_011518058 (OMIM: 602069) PREDICTED: neuropilin- ( 628) 4065 899.9 0
XP_016860674 (OMIM: 602070) PREDICTED: neuropilin- ( 926) 2434 542.9 2.7e-153
NP_003863 (OMIM: 602070) neuropilin-2 isoform 2 pr ( 926) 2434 542.9 2.7e-153
XP_005246990 (OMIM: 602070) PREDICTED: neuropilin- ( 931) 2424 540.7 1.2e-152
XP_005246991 (OMIM: 602070) PREDICTED: neuropilin- ( 931) 2424 540.7 1.2e-152
NP_957718 (OMIM: 602070) neuropilin-2 isoform 1 pr ( 931) 2424 540.7 1.2e-152
XP_016860677 (OMIM: 602070) PREDICTED: neuropilin- ( 848) 2195 490.6 1.4e-137
XP_016860676 (OMIM: 602070) PREDICTED: neuropilin- ( 853) 2195 490.6 1.4e-137
XP_016860675 (OMIM: 602070) PREDICTED: neuropilin- ( 901) 2195 490.6 1.5e-137
NP_957719 (OMIM: 602070) neuropilin-2 isoform 5 pr ( 901) 2195 490.6 1.5e-137
NP_061004 (OMIM: 602070) neuropilin-2 isoform 4 pr ( 906) 2195 490.6 1.5e-137
NP_958436 (OMIM: 602070) neuropilin-2 isoform 3 pr ( 909) 2195 490.6 1.5e-137
NP_957716 (OMIM: 602070) neuropilin-2 isoform 6 pr ( 555) 1998 447.3 9.6e-125
NP_002584 (OMIM: 600270) procollagen C-endopeptida ( 449) 546 129.4 4e-29
NP_005919 (OMIM: 602281) lactadherin isoform a pre ( 387) 541 128.2 7.6e-29
NP_001265571 (OMIM: 606018) EGF-like repeat and di ( 470) 539 127.9 1.2e-28
NP_005702 (OMIM: 606018) EGF-like repeat and disco ( 480) 539 127.9 1.2e-28
NP_001297249 (OMIM: 602281) lactadherin isoform c ( 379) 534 126.7 2.2e-28
NP_001297248 (OMIM: 602281) lactadherin isoform d ( 343) 528 125.4 4.9e-28
NP_001297250 (OMIM: 602281) lactadherin isoform e ( 275) 506 120.5 1.2e-26
XP_011530516 (OMIM: 606742,613087) PREDICTED: toll ( 837) 475 114.0 3.2e-24
XP_016864059 (OMIM: 606742,613087) PREDICTED: toll ( 964) 475 114.0 3.6e-24
NP_036596 (OMIM: 606742,613087) tolloid-like prote (1013) 475 114.0 3.7e-24
XP_011518013 (OMIM: 261100,602997) PREDICTED: cubi (2237) 407 99.4 2.2e-19
XP_011518012 (OMIM: 261100,602997) PREDICTED: cubi (2277) 407 99.4 2.2e-19
XP_011518011 (OMIM: 261100,602997) PREDICTED: cubi (2285) 407 99.4 2.2e-19
NP_963840 (OMIM: 612320) CUB domain-containing pro ( 449) 397 96.8 2.7e-19
XP_011518010 (OMIM: 261100,602997) PREDICTED: cubi (2867) 407 99.4 2.7e-19
NP_001072 (OMIM: 261100,602997) cubilin precursor (3623) 407 99.5 3.2e-19
NP_001108086 (OMIM: 602281) lactadherin isoform b ( 335) 381 93.2 2.4e-18
NP_063916 (OMIM: 134500,300841,306700) coagulation ( 216) 356 87.6 7.3e-17
NP_036597 (OMIM: 606743) tolloid-like protein 2 pr (1015) 358 88.4 1.9e-16
XP_011542919 (OMIM: 112264,614856) PREDICTED: bone ( 622) 353 87.2 2.7e-16
XP_016869227 (OMIM: 112264,614856) PREDICTED: bone ( 717) 353 87.2 3.1e-16
NP_001190 (OMIM: 112264,614856) bone morphogenetic ( 730) 353 87.2 3.1e-16
XP_006716449 (OMIM: 112264,614856) PREDICTED: bone ( 813) 353 87.3 3.4e-16
>>NP_003864 (OMIM: 602069) neuropilin-1 isoform a precur (923 aa)
initn: 6385 init1: 6385 opt: 6385 Z-score: 7548.0 bits: 1407.9 E(85289): 0
Smith-Waterman score: 6385; 100.0% identity (100.0% similar) in 923 aa overlap (1-923:1-923)
10 20 30 40 50 60
pF1KB4 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 CHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 CMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 FEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEGD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 KNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENYN
850 860 870 880 890 900
910 920
pF1KB4 FELVDGVKLKKDKLNTQSTYSEA
:::::::::::::::::::::::
NP_003 FELVDGVKLKKDKLNTQSTYSEA
910 920
>>XP_006717584 (OMIM: 602069) PREDICTED: neuropilin-1 is (924 aa)
initn: 6366 init1: 4786 opt: 6368 Z-score: 7527.9 bits: 1404.2 E(85289): 0
Smith-Waterman score: 6368; 99.8% identity (99.9% similar) in 924 aa overlap (1-923:1-924)
10 20 30 40 50 60
pF1KB4 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_006 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
610 620 630 640 650 660
670 680 690 700 710
pF1KB4 CHWEHDNHVQLKWSVLTSKTGPIQDHT-GDGNFIYSQADENQKGKVARLVSPVVYSQNSA
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_006 CHWEHDNHVQLKWSVLTSKTGPIQDHTAGDGNFIYSQADENQKGKVARLVSPVVYSQNSA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB4 HCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQV
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB4 IFEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IFEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEG
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB4 DKNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENY
850 860 870 880 890 900
900 910 920
pF1KB4 NFELVDGVKLKKDKLNTQSTYSEA
::::::::::::::::::::::::
XP_006 NFELVDGVKLKKDKLNTQSTYSEA
910 920
>>NP_001231902 (OMIM: 602069) neuropilin-1 isoform e pre (916 aa)
initn: 4274 init1: 4274 opt: 6312 Z-score: 7461.7 bits: 1391.9 E(85289): 0
Smith-Waterman score: 6312; 99.2% identity (99.2% similar) in 923 aa overlap (1-923:1-916)
10 20 30 40 50 60
pF1KB4 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
::::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 DECDDDQANCHSGTG-------GTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
610 620 630 640 650
670 680 690 700 710 720
pF1KB4 CHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAH
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 CMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVI
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB4 FEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEGD
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB4 KNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENYN
840 850 860 870 880 890
910 920
pF1KB4 FELVDGVKLKKDKLNTQSTYSEA
:::::::::::::::::::::::
NP_001 FELVDGVKLKKDKLNTQSTYSEA
900 910
>>NP_001231901 (OMIM: 602069) neuropilin-1 isoform d pre (917 aa)
initn: 5854 init1: 4274 opt: 6300 Z-score: 7447.5 bits: 1389.3 E(85289): 0
Smith-Waterman score: 6300; 99.1% identity (99.1% similar) in 924 aa overlap (1-923:1-917)
10 20 30 40 50 60
pF1KB4 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
::::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 DECDDDQANCHSGTG-------GTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
610 620 630 640 650
670 680 690 700 710
pF1KB4 CHWEHDNHVQLKWSVLTSKTGPIQDHT-GDGNFIYSQADENQKGKVARLVSPVVYSQNSA
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
NP_001 CHWEHDNHVQLKWSVLTSKTGPIQDHTAGDGNFIYSQADENQKGKVARLVSPVVYSQNSA
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB4 HCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQV
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB4 IFEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEG
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB4 DKNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENY
840 850 860 870 880 890
900 910 920
pF1KB4 NFELVDGVKLKKDKLNTQSTYSEA
::::::::::::::::::::::::
NP_001 NFELVDGVKLKKDKLNTQSTYSEA
900 910
>>NP_001316997 (OMIM: 602069) neuropilin-1 isoform f pre (906 aa)
initn: 6603 init1: 5644 opt: 5644 Z-score: 6671.4 bits: 1245.7 E(85289): 0
Smith-Waterman score: 6224; 98.0% identity (98.2% similar) in 923 aa overlap (1-923:1-906)
10 20 30 40 50 60
pF1KB4 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 CHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 CMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 FEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEGD
::::::::::::::::::::::::::::::. ::::::::::::
NP_001 FEGEIGKGNLGGIAVDDISINNHISQEDCAR-----------------STPGYEGEGEGD
790 800 810 820
850 860 870 880 890 900
pF1KB4 KNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENYN
830 840 850 860 870 880
910 920
pF1KB4 FELVDGVKLKKDKLNTQSTYSEA
:::::::::::::::::::::::
NP_001 FELVDGVKLKKDKLNTQSTYSEA
890 900
>>XP_006717585 (OMIM: 602069) PREDICTED: neuropilin-1 is (907 aa)
initn: 6235 init1: 4786 opt: 5627 Z-score: 6651.2 bits: 1242.0 E(85289): 0
Smith-Waterman score: 6207; 97.8% identity (98.1% similar) in 924 aa overlap (1-923:1-907)
10 20 30 40 50 60
pF1KB4 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_006 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
610 620 630 640 650 660
670 680 690 700 710
pF1KB4 CHWEHDNHVQLKWSVLTSKTGPIQDHT-GDGNFIYSQADENQKGKVARLVSPVVYSQNSA
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_006 CHWEHDNHVQLKWSVLTSKTGPIQDHTAGDGNFIYSQADENQKGKVARLVSPVVYSQNSA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB4 HCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQV
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB4 IFEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEG
:::::::::::::::::::::::::::::::. :::::::::::
XP_006 IFEGEIGKGNLGGIAVDDISINNHISQEDCAR-----------------STPGYEGEGEG
790 800 810 820
840 850 860 870 880 890
pF1KB4 DKNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENY
830 840 850 860 870 880
900 910 920
pF1KB4 NFELVDGVKLKKDKLNTQSTYSEA
::::::::::::::::::::::::
XP_006 NFELVDGVKLKKDKLNTQSTYSEA
890 900
>>XP_016872354 (OMIM: 602069) PREDICTED: neuropilin-1 is (899 aa)
initn: 6199 init1: 4269 opt: 5566 Z-score: 6579.1 bits: 1228.6 E(85289): 0
Smith-Waterman score: 6146; 97.2% identity (97.4% similar) in 923 aa overlap (1-923:1-899)
10 20 30 40 50 60
pF1KB4 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_016 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 DECDDDQANCHSGTG-------GTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
610 620 630 640 650
670 680 690 700 710 720
pF1KB4 CHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAH
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 CMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVI
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB4 FEGEIGKGNLGGIAVDDISINNHISQEDCAKPADLDKKNPEIKIDETGSTPGYEGEGEGD
::::::::::::::::::::::::::::::. ::::::::::::
XP_016 FEGEIGKGNLGGIAVDDISINNHISQEDCAR-----------------STPGYEGEGEGD
780 790 800 810
850 860 870 880 890 900
pF1KB4 KNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENYN
820 830 840 850 860 870
910 920
pF1KB4 FELVDGVKLKKDKLNTQSTYSEA
:::::::::::::::::::::::
XP_016 FELVDGVKLKKDKLNTQSTYSEA
880 890
>>XP_016872355 (OMIM: 602069) PREDICTED: neuropilin-1 is (742 aa)
initn: 5088 init1: 5088 opt: 5088 Z-score: 6014.8 bits: 1123.9 E(85289): 0
Smith-Waterman score: 5088; 100.0% identity (100.0% similar) in 742 aa overlap (182-923:1-742)
160 170 180 190 200 210
pF1KB4 TTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRL
::::::::::::::::::::::::::::::
XP_016 MSEIILEFESFDLEPDSNPPGGMFCRYDRL
10 20 30
220 230 240 250 260 270
pF1KB4 EIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB4 DFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLG
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB4 LLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTDVV
160 170 180 190 200 210
400 410 420 430 440 450
pF1KB4 VAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVSGLISDSQITSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVSGLISDSQITSSN
220 230 240 250 260 270
460 470 480 490 500 510
pF1KB4 QGDRNWMPENIRLVTSRSGWALPPAPHSYINEWLQIDLGEEKIVRGIIIQGGKHRENKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGDRNWMPENIRLVTSRSGWALPPAPHSYINEWLQIDLGEEKIVRGIIIQGGKHRENKVF
280 290 300 310 320 330
520 530 540 550 560 570
pF1KB4 MRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTFPALSTRFIRIYPERATH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTFPALSTRFIRIYPERATH
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB4 GGLGLRMELLGCEVEAPTAGPTTPNGNLVDECDDDQANCHSGTGDDFQLTGGTTVLATEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLGLRMELLGCEVEAPTAGPTTPNGNLVDECDDDQANCHSGTGDDFQLTGGTTVLATEK
400 410 420 430 440 450
640 650 660 670 680 690
pF1KB4 PTVIDSTIQSEFPTYGFNCEFGWGSHKTFCHWEHDNHVQLKWSVLTSKTGPIQDHTGDGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTVIDSTIQSEFPTYGFNCEFGWGSHKTFCHWEHDNHVQLKWSVLTSKTGPIQDHTGDGN
460 470 480 490 500 510
700 710 720 730 740 750
pF1KB4 FIYSQADENQKGKVARLVSPVVYSQNSAHCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIYSQADENQKGKVARLVSPVVYSQNSAHCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQL
520 530 540 550 560 570
760 770 780 790 800 810
pF1KB4 VWMAIGHQGDHWKEGRVLLHKSLKLYQVIFEGEIGKGNLGGIAVDDISINNHISQEDCAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWMAIGHQGDHWKEGRVLLHKSLKLYQVIFEGEIGKGNLGGIAVDDISINNHISQEDCAK
580 590 600 610 620 630
820 830 840 850 860 870
pF1KB4 PADLDKKNPEIKIDETGSTPGYEGEGEGDKNISRKPGNVLKTLDPILITIIAMSALGVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADLDKKNPEIKIDETGSTPGYEGEGEGDKNISRKPGNVLKTLDPILITIIAMSALGVLL
640 650 660 670 680 690
880 890 900 910 920
pF1KB4 GAVCGVVLYCACWHNGMSERNLSALENYNFELVDGVKLKKDKLNTQSTYSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAVCGVVLYCACWHNGMSERNLSALENYNFELVDGVKLKKDKLNTQSTYSEA
700 710 720 730 740
>>NP_001019799 (OMIM: 602069) neuropilin-1 isoform b pre (644 aa)
initn: 4433 init1: 4433 opt: 4433 Z-score: 5240.7 bits: 980.5 E(85289): 0
Smith-Waterman score: 4433; 100.0% identity (100.0% similar) in 641 aa overlap (1-641:1-641)
10 20 30 40 50 60
pF1KB4 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
:::::::::::::::::::::::::::::::::::::::::
NP_001 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSGIK
610 620 630 640
670 680 690 700 710 720
pF1KB4 CHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAH
>>XP_006717589 (OMIM: 602069) PREDICTED: neuropilin-1 is (663 aa)
initn: 4428 init1: 4428 opt: 4428 Z-score: 5234.6 bits: 979.4 E(85289): 0
Smith-Waterman score: 4428; 99.8% identity (100.0% similar) in 641 aa overlap (1-641:1-641)
10 20 30 40 50 60
pF1KB4 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_006 IKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTF
:::::::::::::::::::::::::::::::::::::::::
XP_006 DECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSARLEVSTLNLSLHNPPQQK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 CHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAH
XP_006 ALI
923 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:16:28 2016 done: Mon Nov 7 20:16:29 2016
Total Scan time: 9.810 Total Display time: 0.290
Function used was FASTA [36.3.4 Apr, 2011]