Result of FASTA (omim) for
pF1KB4796
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4796, 223 aa
1>>>pF1KB4796 223 - 223 aa - 223 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9578+/-0.000409; mu= 15.9868+/- 0.026
mean_var=70.3602+/-14.212, 0's: 0 Z-trim(112.6): 169 B-trim: 607 in 2/51
Lambda= 0.152901
statistics sampled from 21408 (21642) to 21408 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.254), width: 16
Scan time: 6.060
The best scores are: opt bits E(85289)
NP_660294 (OMIM: 615814) serine/threonine/tyrosine ( 223) 1485 336.5 2.1e-92
NP_001124173 (OMIM: 615814) serine/threonine/tyros ( 223) 1485 336.5 2.1e-92
XP_011535410 (OMIM: 615814) PREDICTED: serine/thre ( 199) 1309 297.7 9.2e-81
XP_006720305 (OMIM: 615814) PREDICTED: serine/thre ( 123) 798 184.8 5.5e-47
XP_011535411 (OMIM: 615814) PREDICTED: serine/thre ( 112) 728 169.3 2.3e-42
NP_064570 (OMIM: 616778) dual specificity protein ( 184) 307 76.6 3e-14
NP_001273484 (OMIM: 616778) dual specificity prote ( 205) 307 76.7 3.3e-14
NP_004409 (OMIM: 603068) dual specificity protein ( 314) 306 76.6 5.2e-14
XP_016859035 (OMIM: 603068) PREDICTED: dual specif ( 342) 306 76.6 5.6e-14
XP_016880743 (OMIM: 606779) PREDICTED: protein pho ( 480) 302 75.9 1.3e-13
NP_543152 (OMIM: 611437) dual specificity protein ( 217) 297 74.5 1.6e-13
XP_011518234 (OMIM: 602038) PREDICTED: dual specif ( 625) 302 76.0 1.6e-13
NP_004411 (OMIM: 602038) dual specificity protein ( 625) 302 76.0 1.6e-13
XP_011518235 (OMIM: 602038) PREDICTED: dual specif ( 625) 302 76.0 1.6e-13
NP_001386 (OMIM: 300134) dual specificity protein ( 384) 298 74.9 2.1e-13
XP_011529426 (OMIM: 300134) PREDICTED: dual specif ( 384) 298 74.9 2.1e-13
NP_001305432 (OMIM: 300134) dual specificity prote ( 384) 298 74.9 2.1e-13
XP_011529425 (OMIM: 300134) PREDICTED: dual specif ( 415) 298 74.9 2.2e-13
NP_004408 (OMIM: 600714) dual specificity protein ( 367) 295 74.2 3.2e-13
NP_542178 (OMIM: 616776) dual specificity protein ( 235) 287 72.3 7.7e-13
XP_016880742 (OMIM: 606779) PREDICTED: protein pho ( 529) 289 73.0 1e-12
XP_016883146 (OMIM: 616776) PREDICTED: dual specif ( 298) 283 71.5 1.7e-12
XP_016883145 (OMIM: 616776) PREDICTED: dual specif ( 311) 283 71.5 1.8e-12
XP_016883143 (OMIM: 616776) PREDICTED: dual specif ( 335) 283 71.5 1.9e-12
NP_001307407 (OMIM: 616776) dual specificity prote ( 232) 280 70.8 2.2e-12
XP_016880741 (OMIM: 606779) PREDICTED: protein pho (1328) 288 73.1 2.5e-12
XP_011523708 (OMIM: 606779) PREDICTED: protein pho (1347) 288 73.1 2.5e-12
XP_011523709 (OMIM: 606779) PREDICTED: protein pho (1347) 288 73.1 2.5e-12
XP_011523707 (OMIM: 606779) PREDICTED: protein pho (1394) 288 73.1 2.5e-12
XP_006722212 (OMIM: 606779) PREDICTED: protein pho (1401) 288 73.1 2.6e-12
XP_011523706 (OMIM: 606779) PREDICTED: protein pho (1405) 288 73.1 2.6e-12
NP_203747 (OMIM: 606779) protein phosphatase Sling (1423) 288 73.1 2.6e-12
XP_011523704 (OMIM: 606779) PREDICTED: protein pho (1430) 288 73.2 2.6e-12
XP_005258116 (OMIM: 606779) PREDICTED: protein pho (1430) 288 73.2 2.6e-12
XP_016880740 (OMIM: 606779) PREDICTED: protein pho (1449) 288 73.2 2.6e-12
NP_001269058 (OMIM: 606779) protein phosphatase Sl (1450) 288 73.2 2.6e-12
XP_005258115 (OMIM: 606779) PREDICTED: protein pho (1450) 288 73.2 2.6e-12
NP_009138 (OMIM: 608867) dual specificity protein ( 482) 281 71.2 3.3e-12
NP_001307408 (OMIM: 616776) dual specificity prote ( 295) 276 70.0 4.9e-12
XP_016883144 (OMIM: 616776) PREDICTED: dual specif ( 332) 276 70.0 5.4e-12
NP_004410 (OMIM: 603069) dual specificity protein ( 384) 271 68.9 1.3e-11
XP_011522536 (OMIM: 606618) PREDICTED: dual specif ( 198) 266 67.6 1.7e-11
XP_005257034 (OMIM: 606618) PREDICTED: dual specif ( 198) 266 67.6 1.7e-11
NP_008957 (OMIM: 606618) dual specificity protein ( 198) 266 67.6 1.7e-11
XP_006719218 (OMIM: 607175) PREDICTED: dual specif ( 665) 271 69.1 2e-11
XP_011519159 (OMIM: 607175) PREDICTED: dual specif ( 665) 271 69.1 2e-11
XP_011519158 (OMIM: 607175) PREDICTED: dual specif ( 665) 271 69.1 2e-11
NP_085143 (OMIM: 607175) dual specificity protein ( 665) 271 69.1 2e-11
NP_001154802 (OMIM: 606778) protein phosphatase Sl ( 692) 270 68.9 2.3e-11
NP_001154803 (OMIM: 606778) protein phosphatase Sl ( 703) 270 68.9 2.4e-11
>>NP_660294 (OMIM: 615814) serine/threonine/tyrosine-int (223 aa)
initn: 1485 init1: 1485 opt: 1485 Z-score: 1780.0 bits: 336.5 E(85289): 2.1e-92
Smith-Waterman score: 1485; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
130 140 150 160 170 180
190 200 210 220
pF1KB4 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
:::::::::::::::::::::::::::::::::::::::::::
NP_660 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
190 200 210 220
>>NP_001124173 (OMIM: 615814) serine/threonine/tyrosine- (223 aa)
initn: 1485 init1: 1485 opt: 1485 Z-score: 1780.0 bits: 336.5 E(85289): 2.1e-92
Smith-Waterman score: 1485; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
130 140 150 160 170 180
190 200 210 220
pF1KB4 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
:::::::::::::::::::::::::::::::::::::::::::
NP_001 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
190 200 210 220
>>XP_011535410 (OMIM: 615814) PREDICTED: serine/threonin (199 aa)
initn: 1309 init1: 1309 opt: 1309 Z-score: 1570.9 bits: 297.7 E(85289): 9.2e-81
Smith-Waterman score: 1309; 100.0% identity (100.0% similar) in 199 aa overlap (25-223:1-199)
10 20 30 40 50 60
pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
::::::::::::::::::::::::::::::::::::
XP_011 MRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
10 20 30
70 80 90 100 110 120
pF1KB4 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB4 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
100 110 120 130 140 150
190 200 210 220
pF1KB4 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
:::::::::::::::::::::::::::::::::::::::::::
XP_011 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
160 170 180 190
>>XP_006720305 (OMIM: 615814) PREDICTED: serine/threonin (123 aa)
initn: 798 init1: 798 opt: 798 Z-score: 964.5 bits: 184.8 E(85289): 5.5e-47
Smith-Waterman score: 798; 100.0% identity (100.0% similar) in 123 aa overlap (101-223:1-123)
80 90 100 110 120 130
pF1KB4 FIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAF
::::::::::::::::::::::::::::::
XP_006 MTKEFIDGSLQMGGKVLVHGNAGISRSAAF
10 20 30
140 150 160 170 180 190
pF1KB4 VIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIER
40 50 60 70 80 90
200 210 220
pF1KB4 SLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
:::::::::::::::::::::::::::::::::
XP_006 SLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
100 110 120
>>XP_011535411 (OMIM: 615814) PREDICTED: serine/threonin (112 aa)
initn: 728 init1: 728 opt: 728 Z-score: 881.6 bits: 169.3 E(85289): 2.3e-42
Smith-Waterman score: 728; 100.0% identity (100.0% similar) in 112 aa overlap (112-223:1-112)
90 100 110 120 130 140
pF1KB4 YLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGM
::::::::::::::::::::::::::::::
XP_011 MGGKVLVHGNAGISRSAAFVIAYIMETFGM
10 20 30
150 160 170 180 190 200
pF1KB4 KYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGTTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGTTGS
40 50 60 70 80 90
210 220
pF1KB4 LKRTHEEEDDFGTMQVATAQNG
::::::::::::::::::::::
XP_011 LKRTHEEEDDFGTMQVATAQNG
100 110
>>NP_064570 (OMIM: 616778) dual specificity protein phos (184 aa)
initn: 279 init1: 239 opt: 307 Z-score: 376.8 bits: 76.6 E(85289): 3e-14
Smith-Waterman score: 307; 37.8% identity (67.1% similar) in 143 aa overlap (29-171:5-139)
10 20 30 40 50 60
pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
:..:::::..: ...: .. :.:. .:::
NP_064 MGNGMNKILPGLYIGNFKDARDAEQ--LSKNKVTHI
10 20 30
70 80 90 100 110 120
pF1KB4 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
. .... .: .. . .:: . ::.: .:. : : . .:: : . :::
NP_064 LSVHDSA-----RPMLEGV-KYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHC
40 50 60 70 80
130 140 150 160 170 180
pF1KB4 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
::.:::...:::::: . . ..::. :. : : :::.:: .::::.:
NP_064 LAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQ
90 100 110 120 130 140
190 200 210 220
pF1KB4 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
NP_064 WLKEEYGESPLQDAEEAKNILAAPGILKFWAFLRRL
150 160 170 180
>>NP_001273484 (OMIM: 616778) dual specificity protein p (205 aa)
initn: 279 init1: 239 opt: 307 Z-score: 376.2 bits: 76.7 E(85289): 3.3e-14
Smith-Waterman score: 307; 37.8% identity (67.1% similar) in 143 aa overlap (29-171:5-139)
10 20 30 40 50 60
pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
:..:::::..: ...: .. :.:. .:::
NP_001 MGNGMNKILPGLYIGNFKDARDAEQ--LSKNKVTHI
10 20 30
70 80 90 100 110 120
pF1KB4 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
. .... .: .. . .:: . ::.: .:. : : . .:: : . :::
NP_001 LSVHDSA-----RPMLEGV-KYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHC
40 50 60 70 80
130 140 150 160 170 180
pF1KB4 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
::.:::...:::::: . . ..::. :. : : :::.:: .::::.:
NP_001 LAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQ
90 100 110 120 130 140
190 200 210 220
pF1KB4 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
NP_001 WLKEEYGESPLQDAEEAKNILGKYKEQGRTEPQPGARRWSSFPALAPLTYDNYTTET
150 160 170 180 190 200
>>NP_004409 (OMIM: 603068) dual specificity protein phos (314 aa)
initn: 292 init1: 238 opt: 306 Z-score: 372.5 bits: 76.6 E(85289): 5.2e-14
Smith-Waterman score: 306; 41.8% identity (65.1% similar) in 146 aa overlap (31-175:175-312)
10 20 30 40 50 60
pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
:::: :::: : . .: : :: ::: .
NP_004 EAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLG--SCSHSSDLQGLQACGITAV
150 160 170 180 190 200
70 80 90 100 110
pF1KB4 ICIRQNIEANFIKPN-FQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVH
. :. :. :: :. :::: . . :: . .: .: . ::: . ::.::::
NP_004 L----NVSASC--PNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVH
210 220 230 240 250
120 130 140 150 160 170
pF1KB4 GNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLT
.:::::::.. .::.:.. .. .:: .:..:: :.:: .:. :: ..:. :
NP_004 CQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
260 270 280 290 300 310
180 190 200 210 220
pF1KB4 IQMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
>>XP_016859035 (OMIM: 603068) PREDICTED: dual specificit (342 aa)
initn: 292 init1: 238 opt: 306 Z-score: 371.9 bits: 76.6 E(85289): 5.6e-14
Smith-Waterman score: 306; 41.8% identity (65.1% similar) in 146 aa overlap (31-175:203-340)
10 20 30 40 50 60
pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
:::: :::: : . .: : :: ::: .
XP_016 EAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLG--SCSHSSDLQGLQACGITAV
180 190 200 210 220 230
70 80 90 100 110
pF1KB4 ICIRQNIEANFIKPN-FQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVH
. :. :. :: :. :::: . . :: . .: .: . ::: . ::.::::
XP_016 L----NVSASC--PNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVH
240 250 260 270 280
120 130 140 150 160 170
pF1KB4 GNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLT
.:::::::.. .::.:.. .. .:: .:..:: :.:: .:. :: ..:. :
XP_016 CQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
290 300 310 320 330 340
180 190 200 210 220
pF1KB4 IQMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
>>XP_016880743 (OMIM: 606779) PREDICTED: protein phospha (480 aa)
initn: 257 init1: 228 opt: 302 Z-score: 365.2 bits: 75.9 E(85289): 1.3e-13
Smith-Waterman score: 302; 36.4% identity (67.5% similar) in 151 aa overlap (31-181:337-480)
10 20 30 40 50 60
pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
.:. .::: .: :.: ::..:. .:
XP_016 EMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNA--SNLEDLQNRGVRYI
310 320 330 340 350 360
70 80 90 100 110 120
pF1KB4 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
. . ..:. :: : .:.: . . :. . ... .. : .::. . . :.: :::
XP_016 LNVTREID-NF----FPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHC
370 380 390 400 410
130 140 150 160 170 180
pF1KB4 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
. :.::::. :::: :. .: . :. ::.::: .:: .:..::.::..: ::.::
XP_016 KMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLARLTA
420 430 440 450 460 470
190 200 210 220
pF1KB4 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
.
XP_016 K
480
223 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:43:43 2016 done: Thu Nov 3 21:43:44 2016
Total Scan time: 6.060 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]