Result of FASTA (omim) for
pF1KB4618
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4618, 746 aa
1>>>pF1KB4618 746 - 746 aa - 746 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3329+/-0.000397; mu= 14.0913+/- 0.025
mean_var=71.2243+/-14.973, 0's: 0 Z-trim(112.0): 32 B-trim: 1092 in 1/52
Lambda= 0.151971
statistics sampled from 20796 (20826) to 20796 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.244), width: 16
Scan time: 8.730
The best scores are: opt bits E(85289)
NP_000392 (OMIM: 133701,608210,616682) exostosin-2 ( 751) 4961 1097.4 0
XP_011518253 (OMIM: 133701,608210,616682) PREDICTE ( 731) 4952 1095.4 0
XP_011518252 (OMIM: 133701,608210,616682) PREDICTE ( 764) 4952 1095.4 0
NP_997005 (OMIM: 133701,608210,616682) exostosin-2 ( 718) 4882 1080.0 0
NP_001171554 (OMIM: 133701,608210,616682) exostosi ( 728) 2641 588.7 2.8e-167
XP_011542742 (OMIM: 605744) PREDICTED: exostosin-l ( 919) 915 210.3 2.9e-53
NP_001431 (OMIM: 605744) exostosin-like 3 [Homo sa ( 919) 915 210.3 2.9e-53
NP_004446 (OMIM: 601738) exostosin-like 1 [Homo sa ( 676) 850 196.0 4.2e-49
NP_000118 (OMIM: 133700,215300,608177) exostosin-1 ( 746) 735 170.8 1.8e-41
XP_005245836 (OMIM: 601738) PREDICTED: exostosin-l ( 640) 693 161.6 9.1e-39
NP_001430 (OMIM: 602411) exostosin-like 2 isoform ( 330) 411 99.7 2e-20
XP_005270678 (OMIM: 602411) PREDICTED: exostosin-l ( 330) 411 99.7 2e-20
NP_001028197 (OMIM: 602411) exostosin-like 2 isofo ( 330) 411 99.7 2e-20
NP_001248370 (OMIM: 602411) exostosin-like 2 isofo ( 338) 411 99.7 2e-20
XP_011539296 (OMIM: 602411) PREDICTED: exostosin-l ( 338) 411 99.7 2e-20
XP_011539297 (OMIM: 602411) PREDICTED: exostosin-l ( 338) 411 99.7 2e-20
XP_016856140 (OMIM: 602411) PREDICTED: exostosin-l ( 329) 394 96.0 2.6e-19
NP_001248369 (OMIM: 602411) exostosin-like 2 isofo ( 329) 394 96.0 2.6e-19
XP_011539298 (OMIM: 602411) PREDICTED: exostosin-l ( 337) 394 96.0 2.7e-19
XP_016856139 (OMIM: 601738) PREDICTED: exostosin-l ( 491) 377 92.3 5.1e-18
NP_001248371 (OMIM: 602411) exostosin-like 2 isofo ( 147) 175 48.0 3.4e-05
XP_006718411 (OMIM: 608405) PREDICTED: 1-aminocycl ( 319) 143 41.0 0.0093
>>NP_000392 (OMIM: 133701,608210,616682) exostosin-2 iso (751 aa)
initn: 4952 init1: 4952 opt: 4961 Z-score: 5873.0 bits: 1097.4 E(85289): 0
Smith-Waterman score: 4961; 99.1% identity (99.2% similar) in 738 aa overlap (11-746:14-751)
10 20 30 40 50
pF1KB4 MVVPRSSLLWPRCCVRPG--ECEEEAVCVIMCASVKYNIRGPALIPRMKTKHRIYYI
: : .: :::::::::::::::::::::::::::::::::::::
NP_000 MSCASGSGGGLRHPLRCQKPWDEECEEEAVCVIMCASVKYNIRGPALIPRMKTKHRIYYI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 TLFSIVLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TLFSIVLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 HTCFDVYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HTCFDVYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 NRACLFVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NRACLFVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 DRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYRE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB4 DLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB4 QAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB4 MQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB4 LIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB4 PLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYP
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB4 GRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCE
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB4 DIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTM
670 680 690 700 710 720
720 730 740
pF1KB4 PLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
:::::::::::::::::::::::::::::::
NP_000 PLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
730 740 750
>>XP_011518253 (OMIM: 133701,608210,616682) PREDICTED: e (731 aa)
initn: 4952 init1: 4952 opt: 4952 Z-score: 5862.5 bits: 1095.4 E(85289): 0
Smith-Waterman score: 4952; 100.0% identity (100.0% similar) in 728 aa overlap (19-746:4-731)
10 20 30 40 50 60
pF1KB4 MVVPRSSLLWPRCCVRPGECEEEAVCVIMCASVKYNIRGPALIPRMKTKHRIYYITLFSI
::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLECEEEAVCVIMCASVKYNIRGPALIPRMKTKHRIYYITLFSI
10 20 30 40
70 80 90 100 110 120
pF1KB4 VLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB4 VYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB4 FVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB4 AGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEAL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB4 QVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLS
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB4 DVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQA
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB4 RWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLPLIPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLPLIPPQ
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB4 SQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVV
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB4 RTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHL
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB4 WDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMN
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB4 FLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVV
650 660 670 680 690 700
730 740
pF1KB4 EHRADPVLYKDDFPEKLKSFPNIGSL
::::::::::::::::::::::::::
XP_011 EHRADPVLYKDDFPEKLKSFPNIGSL
710 720 730
>>XP_011518252 (OMIM: 133701,608210,616682) PREDICTED: e (764 aa)
initn: 4952 init1: 4952 opt: 4952 Z-score: 5862.2 bits: 1095.4 E(85289): 0
Smith-Waterman score: 4952; 100.0% identity (100.0% similar) in 728 aa overlap (19-746:37-764)
10 20 30 40
pF1KB4 MVVPRSSLLWPRCCVRPGECEEEAVCVIMCASVKYNIRGPALIPRMKT
::::::::::::::::::::::::::::::
XP_011 SGGGLRHPLRCQKPWDESYSELLFLLEMLLECEEEAVCVIMCASVKYNIRGPALIPRMKT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB4 KHRIYYITLFSIVLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHRIYYITLFSIVLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPER
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB4 GDLSCRMHTCFDVYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDLSCRMHTCFDVYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB4 DYYTDDINRACLFVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYYTDDINRACLFVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYN
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB4 TALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVG
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB4 LHPEYREDLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHPEYREDLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVV
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB4 LRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSI
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB4 PQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSV
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB4 SNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDS
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB4 LWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFP
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB4 DRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 DAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKF
670 680 690 700 710 720
710 720 730 740
pF1KB4 ASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
::::::::::::::::::::::::::::::::::::::
XP_011 ASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
730 740 750 760
>>NP_997005 (OMIM: 133701,608210,616682) exostosin-2 iso (718 aa)
initn: 4882 init1: 4882 opt: 4882 Z-score: 5779.7 bits: 1080.0 E(85289): 0
Smith-Waterman score: 4882; 100.0% identity (100.0% similar) in 718 aa overlap (29-746:1-718)
10 20 30 40 50 60
pF1KB4 MVVPRSSLLWPRCCVRPGECEEEAVCVIMCASVKYNIRGPALIPRMKTKHRIYYITLFSI
::::::::::::::::::::::::::::::::
NP_997 MCASVKYNIRGPALIPRMKTKHRIYYITLFSI
10 20 30
70 80 90 100 110 120
pF1KB4 VLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 VLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB4 VYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 VYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB4 FVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 FVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB4 AGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 AGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEAL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB4 QVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 QVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB4 DVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 DVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB4 RWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLPLIPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 RWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLPLIPPQ
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB4 SQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 SQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVV
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB4 RTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 RTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHL
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB4 WDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 WDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMN
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB4 FLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 FLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVV
640 650 660 670 680 690
730 740
pF1KB4 EHRADPVLYKDDFPEKLKSFPNIGSL
::::::::::::::::::::::::::
NP_997 EHRADPVLYKDDFPEKLKSFPNIGSL
700 710
>>NP_001171554 (OMIM: 133701,608210,616682) exostosin-2 (728 aa)
initn: 4733 init1: 2641 opt: 2641 Z-score: 3124.2 bits: 588.7 E(85289): 2.8e-167
Smith-Waterman score: 4716; 96.3% identity (97.1% similar) in 728 aa overlap (29-746:1-728)
10 20 30 40 50 60
pF1KB4 MVVPRSSLLWPRCCVRPGECEEEAVCVIMCASVKYNIRGPALIPRMKTKHRIYYITLFSI
::::::::::::::::::::::::::::::::
NP_001 MCASVKYNIRGPALIPRMKTKHRIYYITLFSI
10 20 30
70 80 90 100 110 120
pF1KB4 VLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB4 VYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB4 FVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB4 AGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEAL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB4 QVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB4 DVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQL
340 350 360 370 380 390
430 440 450 460 470
pF1KB4 ------RWFWEAYFQSIKAIALATLQ----IINDRIYPYAAISYEEWNDPPAVKWGSVSN
: : : ...... : ::::::::::::::::::::::::::::::
NP_001 FMEPARRENWSAANHQMNSLIWPREQWDSQIINDRIYPYAAISYEEWNDPPAVKWGSVSN
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB4 PLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLW
460 470 480 490 500 510
540 550 560 570 580 590
pF1KB4 PKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDR
520 530 540 550 560 570
600 610 620 630 640 650
pF1KB4 LVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDA
580 590 600 610 620 630
660 670 680 690 700 710
pF1KB4 HMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFAS
640 650 660 670 680 690
720 730 740
pF1KB4 VFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
::::::::::::::::::::::::::::::::::::
NP_001 VFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
700 710 720
>>XP_011542742 (OMIM: 605744) PREDICTED: exostosin-like (919 aa)
initn: 1126 init1: 496 opt: 915 Z-score: 1077.3 bits: 210.3 E(85289): 2.9e-53
Smith-Waterman score: 1216; 33.0% identity (57.9% similar) in 776 aa overlap (94-740:155-916)
70 80 90 100 110 120
pF1KB4 GLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPA--DSPIPE-RGDLSCRMHTCFD
.:. :: :. .: .. .::.:.:::
XP_011 KQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPKATRGCRLHNCFD
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB4 VYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACL
:: .. . . ::.: ..: :: .. ... .. : . : :.. . :::
XP_011 YSRCPLT--SGFPVYVYDSDQFV--FGSYLDPLVKQAFQATARA---NVYVTENADIACL
190 200 210 220 230
190 200 210 220 230
pF1KB4 FVPSIDVLNQNT-LRIKETAQAMAQLSRWDR-GTNHLLFNMLPGGPPDYNTALDVPRDRA
.: . ... . :: : . . .: .: : ::...: : : .: ::
XP_011 YVILVGEMQEPVVLRPAELEKQLYSLPHWRTDGHNHVIIN-LSRKSDTQNLLYNVSTGRA
240 250 260 270 280 290
240 250 260 270 280
pF1KB4 LLAGGGFSTWTYRQGYDVSI-PVYSPLSAE--VDLPEKGPGPRQYFL---------LSSQ
..: . : : :: :.:. . :. .: ...: . : :.:.. : :.
XP_011 MVAQSTFYTVQYRPGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSS
300 310 320 330 340 350
290 300 310 320
pF1KB4 V-----------GLHPEYRED-----LEALQVKHGESVLVLDKCTNLSEGVLSVR-KRCH
. : : .: :.:.: .. ..::: : : . : .. :
XP_011 LQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCG
360 370 380 390 400 410
330 340 350 360 370 380
pF1KB4 KHQVFDYPQVLQEATFCVVLRGA--RL----GQAV-LSDVLQAGCVPVVIADSYILPFSE
... : ..:. .:: ... . :: : :. : ..:..: ::::.... ::...
XP_011 ERE--DRLELLKLSTFALIITPGDPRLVISSGCATRLFEALEVGAVPVVLGEQVQLPYQD
420 430 440 450 460 470
390 400 410 420 430 440
pF1KB4 VLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQII
.:.:..:..:::. ....:. .:.:. . .. :.::.:..::.::.. .: ..: .:
XP_011 MLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMI
480 490 500 510 520 530
450 460
pF1KB4 NDRIYPYAAISYEEW------------------------------NDPPAVK--------
:: :: :: ..:: ..
XP_011 RTRIQIPAAPIREEAAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPRYLRNFT
540 550 560 570 580 590
470 480
pF1KB4 ---------WGSVSNPLFL-------PLIP-------------PQSQG------------
:. . .:. : :..: : . :
XP_011 LTVTDFYRSWNCAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAAL
600 610 620 630 640 650
490 500 510 520 530
pF1KB4 --------FTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRV
::...:::.: : :. . ... .: :.:..::::. : : :: ::: : :
XP_011 GGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSP-KLPSEDLLWPDIGV
660 670 680 690 700 710
540 550 560 570 580 590
pF1KB4 PLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYP
:. :::: .:.:.:::.:..::::::.:.:::: : ::..::..:::: ::.::.:
XP_011 PIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDA-HLRHDEIMFGFRVWREARDRIVGFP
720 730 740 750 760 770
600 610 620 630 640 650
pF1KB4 GRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCE
:: : :: ..: :.:... :.:::::::::.:::. :::.: :: :.. :: ..:::
XP_011 GRYHAWDIPHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCE
780 790 800 810 820 830
660 670 680 690 700 710
pF1KB4 DIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTM
::::::::...: : :::: : :.:: : ..:: :..:. :: .::: :..:.: :
XP_011 DIAMNFLVSHITRKPPIKVTSRWTFRCPGCP--QALSHDDSHFHERHKCINFFVKVYGYM
840 850 860 870 880 890
720 730 740
pF1KB4 PLKVVEHRADPVLYKDDFP-EKLKSFPNIGSL
:: .. :.: ::.: .: .: : :
XP_011 PLLYTQFRVDSVLFKTRLPHDKTKCFKFI
900 910
>>NP_001431 (OMIM: 605744) exostosin-like 3 [Homo sapien (919 aa)
initn: 1126 init1: 496 opt: 915 Z-score: 1077.3 bits: 210.3 E(85289): 2.9e-53
Smith-Waterman score: 1216; 33.0% identity (57.9% similar) in 776 aa overlap (94-740:155-916)
70 80 90 100 110 120
pF1KB4 GLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPA--DSPIPE-RGDLSCRMHTCFD
.:. :: :. .: .. .::.:.:::
NP_001 KQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPKATRGCRLHNCFD
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB4 VYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACL
:: .. . . ::.: ..: :: .. ... .. : . : :.. . :::
NP_001 YSRCPLT--SGFPVYVYDSDQFV--FGSYLDPLVKQAFQATARA---NVYVTENADIACL
190 200 210 220 230
190 200 210 220 230
pF1KB4 FVPSIDVLNQNT-LRIKETAQAMAQLSRWDR-GTNHLLFNMLPGGPPDYNTALDVPRDRA
.: . ... . :: : . . .: .: : ::...: : : .: ::
NP_001 YVILVGEMQEPVVLRPAELEKQLYSLPHWRTDGHNHVIIN-LSRKSDTQNLLYNVSTGRA
240 250 260 270 280 290
240 250 260 270 280
pF1KB4 LLAGGGFSTWTYRQGYDVSI-PVYSPLSAE--VDLPEKGPGPRQYFL---------LSSQ
..: . : : :: :.:. . :. .: ...: . : :.:.. : :.
NP_001 MVAQSTFYTVQYRPGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSS
300 310 320 330 340 350
290 300 310 320
pF1KB4 V-----------GLHPEYRED-----LEALQVKHGESVLVLDKCTNLSEGVLSVR-KRCH
. : : .: :.:.: .. ..::: : : . : .. :
NP_001 LQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCG
360 370 380 390 400 410
330 340 350 360 370 380
pF1KB4 KHQVFDYPQVLQEATFCVVLRGA--RL----GQAV-LSDVLQAGCVPVVIADSYILPFSE
... : ..:. .:: ... . :: : :. : ..:..: ::::.... ::...
NP_001 ERE--DRLELLKLSTFALIITPGDPRLVISSGCATRLFEALEVGAVPVVLGEQVQLPYQD
420 430 440 450 460 470
390 400 410 420 430 440
pF1KB4 VLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQII
.:.:..:..:::. ....:. .:.:. . .. :.::.:..::.::.. .: ..: .:
NP_001 MLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMI
480 490 500 510 520 530
450 460
pF1KB4 NDRIYPYAAISYEEW------------------------------NDPPAVK--------
:: :: :: ..:: ..
NP_001 RTRIQIPAAPIREEAAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPRYLRNFT
540 550 560 570 580 590
470 480
pF1KB4 ---------WGSVSNPLFL-------PLIP-------------PQSQG------------
:. . .:. : :..: : . :
NP_001 LTVTDFYRSWNCAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAAL
600 610 620 630 640 650
490 500 510 520 530
pF1KB4 --------FTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRV
::...:::.: : :. . ... .: :.:..::::. : : :: ::: : :
NP_001 GGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSP-KLPSEDLLWPDIGV
660 670 680 690 700 710
540 550 560 570 580 590
pF1KB4 PLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYP
:. :::: .:.:.:::.:..::::::.:.:::: : ::..::..:::: ::.::.:
NP_001 PIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDA-HLRHDEIMFGFRVWREARDRIVGFP
720 730 740 750 760 770
600 610 620 630 640 650
pF1KB4 GRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCE
:: : :: ..: :.:... :.:::::::::.:::. :::.: :: :.. :: ..:::
NP_001 GRYHAWDIPHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCE
780 790 800 810 820 830
660 670 680 690 700 710
pF1KB4 DIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTM
::::::::...: : :::: : :.:: : ..:: :..:. :: .::: :..:.: :
NP_001 DIAMNFLVSHITRKPPIKVTSRWTFRCPGCP--QALSHDDSHFHERHKCINFFVKVYGYM
840 850 860 870 880 890
720 730 740
pF1KB4 PLKVVEHRADPVLYKDDFP-EKLKSFPNIGSL
:: .. :.: ::.: .: .: : :
NP_001 PLLYTQFRVDSVLFKTRLPHDKTKCFKFI
900 910
>>NP_004446 (OMIM: 601738) exostosin-like 1 [Homo sapien (676 aa)
initn: 839 init1: 418 opt: 850 Z-score: 1002.6 bits: 196.0 E(85289): 4.2e-49
Smith-Waterman score: 991; 31.2% identity (58.8% similar) in 658 aa overlap (99-740:64-670)
70 80 90 100 110 120
pF1KB4 GMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDL--SCRMHTCFDVYRCGF
:: :. : .. :: ..:::. .:
NP_004 LPPRPRPGASQGWPRWLDAELLQSFSQPGELPEDAVSPPQAPHGGSCNWESCFDTSKCR-
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB4 NPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACLFVPSID
. .::..: . .:::. . ..: .: : .:: . :::..
NP_004 --GDGLKVFVYP-----------AVGTISETHRRILASIEGSRFYTFSPAGACLLL----
100 110 120 130
190 200 210 220 230 240
pF1KB4 VLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFS
.:. .. .:.. .. .:.:: :::.. . :. : . : .:..: .. .
NP_004 LLSLDA----QTGECSSMPLQWNRGRNHLVLRLHPA-PCPRTFQLG----QAMVAEASPT
140 150 160 170 180
250 260 270 280 290 300
pF1KB4 TWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEALQVKHGE
. ..: :.::..: . : . : .: .: : : : :. : ::. ..:
NP_004 VDSFRPGFDVALP-FLPEAH----PLRGGAPGQLRQHSPQPGVA------LLALEEERGG
190 200 210 220 230
310 320 330 340 350 360
pF1KB4 SVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQ---VLQEATFCVVLRGARLGQAV-LSDV
. .. . .. ::.. : .: .::::.. : : : . ..
NP_004 W-----RTADTGSSACPWDGRCEQDPGPGQTQRQETLPNATFCLI-SGHRPEAASRFLQA
240 250 260 270 280
370 380 390 400 410 420
pF1KB4 LQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARW
:::::.::... . ::::::.:: .:..:. :. .: . :: . .. ...:...
NP_004 LQAGCIPVLLSPRWELPFSEVIDWTKAAIVADERLPLQVLAALQEMSPARVLALRQQTQF
290 300 310 320 330 340
430 440 450 460 470
pF1KB4 FWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPP----AVKWGSVSNPLFLPLIP
.:.:::.:.. . .::..:.:::. .: ::.:: :.. :.: : .:.
NP_004 LWDAYFSSVEKVIHTTLEVIQDRIFGTSAHPSLLWNSPPGALLALSTFSTS-PQDFPFYY
350 360 370 380 390 400
480 490 500 510 520 530
pF1KB4 PQSQG------FTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPK
: :: :.:.. . . ...: :. ...::.:.:. : : ::.
NP_004 LQ-QGSRPEGRFSALIWVGPPGQPPLKLIQAVAGSQHCAQILVLWSNER---PLPSRWPE
410 420 430 440 450 460
540 550 560 570 580 590
pF1KB4 IRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLV
::: :. .. :.:.::.::. :.:.:.:..: . :: :..:.. ::. ::.:.:
NP_004 TAVPLTVI-DGHRKVSDRFYPYSTIRTDAILSLDARSSLSTS-EVDFAFLVWQSFPERMV
470 480 490 500 510 520
600 610 620 630 640 650
pF1KB4 GYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHM
:. :.::. . : : .: ::: ::::: :::::.:.. :.:...: ... .:
NP_004 GFLTSSHFWDEAHGGWGYTAERTNEFSMVLTTAAFYHRYYHTLFTHSLPKALRTLADEAP
530 540 550 560 570 580
660 670 680 690 700 710
pF1KB4 NCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVF
.: :. :::.:: :: ::: :. . : : . . .:::..:..:
NP_004 TCVDVLMNFIVAAVTKLPPIKVPYGKQRQEAAPLAPGGPGPRPKPPAPAPDCINQIAAAF
590 600 610 620 630 640
720 730 740
pF1KB4 GTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
: ::: . : ::::.:: . :..
NP_004 GHMPLLSSRLRLDPVLFKDPVSVQRKKYRSLEKP
650 660 670
>>NP_000118 (OMIM: 133700,215300,608177) exostosin-1 [Ho (746 aa)
initn: 1311 init1: 424 opt: 735 Z-score: 865.6 bits: 170.8 E(85289): 1.8e-41
Smith-Waterman score: 1433; 35.7% identity (64.9% similar) in 715 aa overlap (72-746:53-746)
50 60 70 80 90
pF1KB4 LIPRMKTKHRIYYITLFSIVLLGLIATGMFQFWPH---SIESSNDWNV---EKRSIRDVP
.:::. ... :. : :.. :
NP_000 FGGLQFRASRSHSRREEHSGRNGLHHPSPDHFWPRFPDALRPFVPWDQLENEDSSVHISP
30 40 50 60 70 80
100 110 120 130 140 150
pF1KB4 VVRLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTIS
. :.: : .: .:::..::: : :: .:::.: .: .. :.
NP_000 RQKRDANSSI-YKGK-KCRMESCFDFTLC---KKNGFKVYVYPQQK---------GEKIA
90 100 110 120
160 170 180 190 200 210
pF1KB4 REYNELLMAISDSDYYTDDINRACLFVPSIDVLNQNTLR---IKETAQAMAQLSRWDRGT
. :...: :: : .::.: ..::::: :.:.:... : ... . . .: :. :
NP_000 ESYQNILAAIEGSRFYTSDPSQACLFVLSLDTLDRDQLSPQYVHNLRSKVQSLHLWNNGR
130 140 150 160 170 180
220 230 240 250 260 270
pF1KB4 NHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPE
:::.::. : :::. . .:.:: ...:: ..: ..:::::..: .. :
NP_000 NHLIFNLYSGTWPDYTEDVGFDIGQAMLAKASISTENFRPNFDVSIPLFSKDHPRTG-GE
190 200 210 220 230 240
280 290 300 310 320
pF1KB4 KG-------PGPRQYFLLSSQ----VGLHPEYREDLEALQVKHGESVLVLDKCTNLSEGV
.: : :.:.:. . .:. . :. : .:..::.:..: : . ..
NP_000 RGFLKFNTIPPLRKYMLVFKGKRYLTGIGSDTRNAL--YHVHNGEDVVLLTTCKHGKDWQ
250 260 270 280 290 300
330 340 350 360 370
pF1KB4 LSVRKRCHK----HQVFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVVIADSYI
.:: . .. .:: ..:..::::.: :: :::. . ..:::.::::......
NP_000 KHKDSRCDRDNTEYEKYDYREMLHNATFCLVPRGRRLGSFRFLEALQAACVPVMLSNGWE
310 320 330 340 350 360
380 390 400 410 420 430
pF1KB4 LPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARWFWEAYFQSIKAIALA
::::::..:..:.:. :. . .. : ..:: : .: ...:....:::::.:.. :.:.
NP_000 LPFSEVINWNQAAVIGDERLLLQIPSTIRSIHQDKILALRQQTQFLWEAYFSSVEKIVLT
370 380 390 400 410 420
440 450 460 470 480
pF1KB4 TLQIINDRIYPYAAISYEEWNDPPA-----VKWGSVSN--PLF---LPLIPPQSQGFTAI
::.::.:::. . . . :: :. ...: . : . : : ::.. :::.
NP_000 TLEIIQDRIFKHISRNSLIWNKHPGGLFVLPQYSSYLGDFPYYYANLGLKPPSK--FTAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VLTY----DRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTA
. . .. . ...... ..: ....:.:: .: : :: ::. :..
NP_000 IHAVTPLVSQSQPVLKLLVAAAKSQYCAQIIVLWNC-DKPLPAKHRWPATAVPVVVIEGE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 ENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDH
. .:.::.:::.: :.:::..:.: . :.. :..:.. ::. ::.:.::::.: :.::.
NP_000 SKVMSSRFLPYDNIITDAVLSLDEDTV-LSTTEVDFAFTVWQSFPERIVGYPARSHFWDN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 EMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLV
..: : :.:::. ::::::::.::::..:::.. .:...:: :: ::::: :::::
NP_000 SKERWGYTSKWTNDYSMVLTGAAIYHKYYHYLYSHYLPASLKNMVDQLANCEDILMNFLV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 ANVTGKAVIKVTPRKKFKCPECTAIDGLS--LDQTHMVERSECINKFASVFGTMPLKVVE
. :: :::: .:..: . : : :...:. :.: ::: :: ::: .
NP_000 SAVTKLPPIKVTQKKQYKETMMGQTSRASRWADPDHFAQRQSCMNTFASWFGYMPLIHSQ
670 680 690 700 710 720
730 740
pF1KB4 HRADPVLYKDDFPEKLKSFPNIGSL
: ::::.::. :.. .: :
NP_000 MRLDPVLFKDQVSILRKKYRDIERL
730 740
>>XP_005245836 (OMIM: 601738) PREDICTED: exostosin-like (640 aa)
initn: 684 init1: 418 opt: 693 Z-score: 817.0 bits: 161.6 E(85289): 9.1e-39
Smith-Waterman score: 799; 29.4% identity (55.1% similar) in 657 aa overlap (99-740:64-634)
70 80 90 100 110 120
pF1KB4 GMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDL--SCRMHTCFDVYRCGF
:: :. : .. :: ..:::. .:
XP_005 LPPRPRPGASQGWPRWLDAELLQSFSQPGELPEDAVSPPQAPHGGSCNWESCFDTSKCR-
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB4 NPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACLFVPSID
. .::..: . .:::. . ..: .: : .:: . :::..
XP_005 --GDGLKVFVYP-----------AVGTISETHRRILASIEGSRFYTFSPAGACLLL----
100 110 120 130
190 200 210 220 230 240
pF1KB4 VLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFS
.:. .. .:.. .. .:.:: :::.. . :. : . : .:..: .. .
XP_005 LLSLDA----QTGECSSMPLQWNRGRNHLVLRLHPA-PCPRTFQLG----QAMVAEASPT
140 150 160 170 180
250 260 270 280 290 300
pF1KB4 TWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEALQVKHGE
. ..: :.::..: . : . : .: .: : : : :. : ::. ..:
XP_005 VDSFRPGFDVALP-FLPEAH----PLRGGAPGQLRQHSPQPGVA------LLALEEERGG
190 200 210 220 230
310 320 330 340 350 360
pF1KB4 SVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQ---VLQEATFCVVLRGARLGQAVLSDVL
. .. . .. ::.. : .: .::::.. : : : : :
XP_005 W-----RTADTGSSACPWDGRCEQDPGPGQTQRQETLPNATFCLI-SGHRPEAA--SRFL
240 250 260 270 280
370 380 390 400 410 420
pF1KB4 QAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARWF
:: .:.. ..:: : : . ...:....
XP_005 QA-----------------------LQVLAALQEMS---------PAR-VLALRQQTQFL
290 300 310
430 440 450 460 470
pF1KB4 WEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPP----AVKWGSVSNPLFLPLIPP
:.:::.:.. . .::..:.:::. .: ::.:: :.. :.: : .:.
XP_005 WDAYFSSVEKVIHTTLEVIQDRIFGTSAHPSLLWNSPPGALLALSTFSTS-PQDFPFYYL
320 330 340 350 360 370
480 490 500 510 520 530
pF1KB4 QSQG------FTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKI
: :: :.:.. . . ...: :. ...::.:.:. : : ::.
XP_005 Q-QGSRPEGRFSALIWVGPPGQPPLKLIQAVAGSQHCAQILVLWSNER---PLPSRWPET
380 390 400 410 420
540 550 560 570 580 590
pF1KB4 RVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVG
::: :. .. :.:.::.::. :.:.:.:..: . :: :..:.. ::. ::.:.::
XP_005 AVPLTVI-DGHRKVSDRFYPYSTIRTDAILSLDARSSLSTS-EVDFAFLVWQSFPERMVG
430 440 450 460 470 480
600 610 620 630 640 650
pF1KB4 YPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMN
. :.::. . : : .: ::: ::::: :::::.:.. :.:...: ... .: .
XP_005 FLTSSHFWDEAHGGWGYTAERTNEFSMVLTTAAFYHRYYHTLFTHSLPKALRTLADEAPT
490 500 510 520 530 540
660 670 680 690 700 710
pF1KB4 CEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFG
: :. :::.:: :: ::: :. . : : . . .:::..:..::
XP_005 CVDVLMNFIVAAVTKLPPIKVPYGKQRQEAAPLAPGGPGPRPKPPAPAPDCINQIAAAFG
550 560 570 580 590 600
720 730 740
pF1KB4 TMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
::: . : ::::.:: . :..
XP_005 HMPLLSSRLRLDPVLFKDPVSVQRKKYRSLEKP
610 620 630 640
746 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:39:30 2016 done: Thu Nov 3 21:39:32 2016
Total Scan time: 8.730 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]